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Hong-Biao Huang · SciRah

Researcher profile · Semantic Scholar

Hong-Biao Huang

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Hong-Biao Huang — researcher profile on SciRah

h-index: 37
Works: 89
Citations: 3,554

Most-cited papers

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth
Ning-Ning Liu, Xiao-Fen Li, Hong-Biao Huang, Chong Zhao +19 more
2014OncoTarget165 citations Open access
Semantic Scholar
Shikonin Exerts Antitumor Activity via Proteasome Inhibition and Cell Death Induction in vitro and in vivo
Huanjie Yang, P. Zhou, Hong-Biao Huang, Di Chen +9 more
2009International Journal of Cancer161 citations Open access
Semantic Scholar
Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition
Li Lu, Ai-Ping Qin, Hong-Biao Huang, P. Zhou +9 more
2011European Journal of Pharmacology157 citations Open access
Semantic Scholar
Physiological levels of ATP Negatively Regulate Proteasome Function
Hong-Biao Huang, Xiaoyan Zhang, Shu-Jue Li, Ning-Ning Liu +15 more
2010Cell Research155 citations Open access
Semantic Scholar
Gambogic Acid Induces Apoptosis in Imatinib-Resistant Chronic Myeloid Leukemia Cells via Inducing Proteasome Inhibition and Caspase-Dependent Bcr-Abl Downregulation
Xian-Ping Shi, Xin Chen, Xiao-Fen Li, X. Lan +12 more
2013Clinical Cancer Research130 citations Open access
Semantic Scholar
MiR-454-3p-Mediated Wnt/β-catenin Signaling Antagonists Suppression Promotes Breast Cancer Metastasis
L. Ren, Han Chen, Jun-Wei Song, Xuhong Chen +12 more
2019Theranostics120 citations Open access
Semantic Scholar
Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination
Yu-Ning Liao, Xiao-Hong Xia, Ning-Ning Liu, Jianyu Cai +7 more
2018Oncogene113 citations Open access
Semantic Scholar
Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor
Yu-Ning Liao, Ning-Ning Liu, X. Hua, Jianyu Cai +4 more
2017Cell Death and Disease111 citations Open access
Semantic Scholar
L-Carnitine Is an Endogenous HDAC Inhibitor Selectively Inhibiting Cancer Cell Growth In Vivo and In Vitro
Hong-Biao Huang, Ning-Ning Liu, Hai-Ping Guo, S. Liao +12 more
2012PLoS ONE95 citations Open access
Semantic Scholar
Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer
Yu-Ning Liao, Zhiqiang Guo, Xiao-Hong Xia, Yuan Liu +5 more
2019Journal of experimental & clinical cancer research : CR92 citations Open access
Semantic Scholar
Gambogic acid is a tissue-specific proteasome inhibitor in vitro and in vivo.
Xiao-Fen Li, Shou-Ting Liu, Hong-Biao Huang, Ning-Ning Liu +25 more
2013Cell Reports90 citations Open access
Semantic Scholar
Deubiquitination and stabilization of Estrogen Receptor α by Ubiquitin-Specific Protease 7 promotes breast tumorigenesis.
Xiao-Hong Xia, Yu-Ning Liao, Chuyi Huang, Yuan Liu +6 more
2019Cancer Letters87 citations
Semantic Scholar
Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide
Xiao-Hong Xia, Chuyi Huang, Yu-Ning Liao, Yuan Liu +6 more
2019Journal of experimental & clinical cancer research : CR84 citations Open access
Semantic Scholar
USP10 modulates the SKP2/Bcr-Abl axis via stabilizing SKP2 in chronic myeloid leukemia
Yu-Ning Liao, Ning-Ning Liu, Xiao-Hong Xia, Zhiqiang Guo +6 more
2019Cell Discovery82 citations Open access
Semantic Scholar
Cytoplasmic RAP1 mediates cisplatin resistance of non-small cell lung cancer
Lu Xiao, X. Lan, Xian-Ping Shi, K. Zhao +5 more
2017Cell Death and Disease76 citations Open access
Semantic Scholar
A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases
Ning-Ning Liu, Chun-Jiao Liu, Xiao-Fen Li, S. Liao +16 more
2014Scientific Reports76 citations Open access
Semantic Scholar
Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms
Xin Chen, Xian-Ping Shi, Chong Zhao, Xiao-Fen Li +12 more
2014OncoTarget74 citations Open access
Semantic Scholar
Gambogic acid enhances proteasome inhibitor-induced anticancer activity
Hong-Biao Huang, Di Chen, Shu-Jue Li, Xiao-Fen Li +13 more
2011Cancer Letters67 citations Open access
Semantic Scholar
Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo
Hong-Biao Huang, Yu-Ning Liao, Ning-Ning Liu, X. Hua +12 more
2015OncoTarget65 citations Open access
Semantic Scholar
Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy
Yu-Ning Liao, Yuan Liu, Xiao-Hong Xia, Zhen-Long Shao +6 more
2020Theranostics64 citations Open access
Semantic Scholar
NCAPG confers trastuzumab resistance via activating SRC/STAT3 signaling pathway in HER2-positive breast cancer
Li-Li Jiang, L. Ren, Han Chen, Jinyuan Pan +12 more
2020Cell Death and Disease59 citations Open access
Semantic Scholar
HSP90β Impedes STUB1‐Induced Ubiquitination of YTHDF2 to Drive Sorafenib Resistance in Hepatocellular Carcinoma
Yu-Ning Liao, Yuan Liu, Cuifu Yu, Q. Lei +8 more
2023Advancement of science58 citations Open access
Semantic Scholar
Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer
Xiao-Hong Xia, Yu-Ning Liao, Zhiqiang Guo, Yan-Ling Li +8 more
2018Oncogenesis58 citations Open access
Semantic Scholar
Deubiquitination of CD36 by UCHL1 promotes foam cell formation
Xiao-Hong Xia, Qiong Xu, Mingke Liu, Xu-Ke Chen +7 more
2020Cell Death and Disease55 citations Open access
Semantic Scholar
USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells
Yu-Ning Liao, Zhen-Long Shao, Yuan Liu, Xiao-Hong Xia +12 more
2021Journal of experimental & clinical cancer research : CR47 citations Open access
Semantic Scholar
Overexpression of PIMREG promotes breast cancer aggressiveness via constitutive activation of NF-κB signaling
Li-Li Jiang, L. Ren, Xiao-Lan Zhang, Han Chen +11 more
2019EBioMedicine47 citations Open access
Semantic Scholar
The deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression
Xiao-Hong Xia, Chuyi Huang, Yu-Ning Liao, Yuan Liu +7 more
2021Cell Death and Disease44 citations Open access
Semantic Scholar
A novel deubiquitinase inhibitor b-AP15 triggers apoptosis in both androgen receptor-dependent and -independent prostate cancers
Jianyu Cai, Xiao-Hong Xia, Yu-Ning Liao, Ning-Ning Liu +10 more
2017OncoTarget44 citations Open access
Semantic Scholar
Anacardic acid induces cell apoptosis associated with induction of ATF4-dependent endoplasmic reticulum stress.
Hong-Biao Huang, X. Hua, Ning-Ning Liu, Xiao-Fen Li +7 more
2014Toxicology Letters43 citations
Semantic Scholar
Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds
Ning-Ning Liu, Hong-Biao Huang, Ping Q. Dou, Jin-Bao Liu
2015Oncoscience42 citations Open access
Semantic Scholar
USP14 inhibition promotes recovery by protecting BBB integrity and attenuating neuroinflammation in MCAO mice
Wen-Zhong Hou, Jian-Ping Yao, Jun-Jie Liu, Xiaohong Lin +6 more
2023CNS Neuroscience & Therapeutics40 citations Open access
Semantic Scholar
Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases
Chong Zhao, Xin Chen, Chang-Shan Yang, D. Zang +14 more
2017OncoTarget39 citations Open access
Semantic Scholar
A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance
Yu-Ning Liao, Yuan Liu, Zhen-Long Shao, Xiao-Hong Xia +11 more
2021Oncogene38 citations
Semantic Scholar
Selective degradation of AR-V7 to overcome castration resistance of prostate cancer
Yuan Liu, Cuifu Yu, Zhen-Long Shao, Xiao-Hong Xia +7 more
2021Cell Death and Disease38 citations Open access
Semantic Scholar
Auranofin lethality to prostate cancer includes inhibition of proteasomal deubiquitinases and disrupted androgen receptor signaling
Ning-Ning Liu, Zhiqiang Guo, Xiao-Hong Xia, Yu-Ning Liao +8 more
2019European Journal of Pharmacology38 citations
Semantic Scholar
Parkin facilitates proteasome inhibitor-induced apoptosis via suppression of NF-κB activity in hepatocellular carcinoma
Xiao-Lan Zhang, Chun Lin, Jun-Wei Song, Han Chen +13 more
2019Cell Death and Disease38 citations Open access
Semantic Scholar
Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy
Chong Zhao, Xin Chen, D. Zang, X. Lan +14 more
2016Biochemical Pharmacology38 citations Open access
Semantic Scholar
Bilirubin neurotoxicity is associated with proteasome inhibition
Hong-Biao Huang, Mingxing Guo, Ning-Ning Liu, Chong Zhao +16 more
2017Cell Death and Disease37 citations Open access
Semantic Scholar
Ubiquitin-specific protease 14 regulates cardiac hypertrophy progression by increasing GSK-3β phosphorylation.
Ning-Ning Liu, Ren-Jie Chai, Bin Liu, Zhen-Hui Zhang +9 more
2016Biochemical and Biophysical Research Communications - BBRC37 citations
Semantic Scholar
HDAC Inhibitor L-Carnitine and Proteasome Inhibitor Bortezomib Synergistically Exert Anti-Tumor Activity In Vitro and In Vivo
Hong-Biao Huang, Ning-Ning Liu, Chang-Shan Yang, S. Liao +13 more
2012PLoS ONE33 citations Open access
Semantic Scholar
A microRNA-mediated decrease in eukaryotic initiation factor 2α promotes cell survival during PS-341 treatment
Li-Li Jiang, D. Zang, Songgang Yi, Xiao-Fen Li +11 more
2016Scientific Reports32 citations Open access
Semantic Scholar
Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis
Shuo-yi Jiang, Xiao-Ge Wang, Yuan-ming He, Hong-Biao Huang +6 more
2021Cell Death and Disease31 citations Open access
Semantic Scholar
Sanggenon C decreases tumor cell viability associated with proteasome inhibition
Hong-Biao Huang, Ning-Ning Liu, K. Zhao, Chenchen Zhu +17 more
2011Frontiers in Bioscience30 citations Open access
Semantic Scholar
Gambogic acid induces apoptosis in diffuse large B-cell lymphoma cells via inducing proteasome inhibition
Xian-Ping Shi, X. Lan, Xin Chen, Chong Zhao +9 more
2015Scientific Reports28 citations Open access
Semantic Scholar
Intracellular ATP Concentration Contributes to the Cytotoxic and Cytoprotective Effects of Adenosine
Shu-Jue Li, Xiao-Fen Li, Hai-Ping Guo, Shou-Ting Liu +5 more
2013PLoS ONE26 citations Open access
Semantic Scholar
SNS-023 sensitizes hepatocellular carcinoma to sorafenib by inducing degradation of cancer drivers SIX1 and RPS16
Yuan Liu, Wei-Yao Kong, Cuifu Yu, Zhen-Long Shao +11 more
2022Acta Pharmacologica Sinica25 citations Open access
Semantic Scholar
Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation.
Ning-Ning Liu, Hong-Biao Huang, Shou-Ting Liu, Xiao-Fen Li +3 more
2014Toxicology in Vitro25 citations
Semantic Scholar
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression
Xiao-Hong Xia, Tumei Hu, Xiao-Yue He, Yuan Liu +6 more
2023International Journal on Biological Sciences24 citations Open access
Semantic Scholar
The combination of proteasome inhibitors bortezomib and gambogic acid triggers synergistic cytotoxicity in vitro but not in vivo.
Ning-Ning Liu, Hong-Biao Huang, Li Xu, X. Hua +8 more
2014Toxicology Letters24 citations
Semantic Scholar
USP10 deletion inhibits macrophage-derived foam cell formation and cellular-oxidized low density lipoprotein uptake by promoting the degradation of CD36
Xiao-Hong Xia, Tumei Hu, Jinchan He, Qiong Xu +6 more
2020Aging23 citations Open access
Semantic Scholar

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