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A. P. Femia · SciRah

Researcher profile · Semantic Scholar

A. P. Femia

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A. P. Femia — researcher profile on SciRah

h-index: 25
Works: 47
Citations: 2,341

Most-cited papers

Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F344 rats.
P. Dolara, C. Luceri, C. de Filippo, A. P. Femia +6 more
2005Mutation research363 citations
Semantic Scholar
Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats.
A. P. Femia, C. Luceri, P. Dolara, A. Giannini +6 more
2002Carcinogenesis339 citations Open access
Semantic Scholar
Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: correlation with carcinogenesis.
G. Caderni, A. P. Femia, A. Giannini, Alessandro Favuzza +3 more
2003Cancer Research188 citations
Semantic Scholar
Intestinal immunity of rats with colon cancer is modulated by oligofructose-enriched inulin combined with Lactobacillus rhamnosus and Bifidobacterium lactis.
M. Roller, A. P. Femia, G. Caderni, G. Rechkemmer +1 more
2004British Journal of Nutrition133 citations Open access
Semantic Scholar
Effect of butyrate enemas on gene expression profiles and endoscopic/histopathological scores of diverted colorectal mucosa: A randomized trial.
C. Luceri, A. P. Femia, M. Fazi, C. Di Martino +3 more
2016Digestive and Liver Disease93 citations Open access
Semantic Scholar
Fecal Water Genotoxicity Is Predictive of Tumor-Preventive Activities by Inulin-Like Oligofructoses, Probiotics (Lactobacillus rhamnosus and Bifidobacterium lactis), and Their Synbiotic Combination
A. Klinder, A. Forster, G. Caderni, A. P. Femia +1 more
2004Nutrition and Cancer92 citations
Semantic Scholar
Mucin-depleted foci (MDF) in the colon of rats treated with azoxymethane (AOM) are useful biomarkers for colon carcinogenesis.
A. P. Femia, P. Dolara, G. Caderni
2003Carcinogenesis87 citations
Semantic Scholar
Aging related changes in circulating reactive oxygen species (ROS) and protein carbonyls are indicative of liver oxidative injury
C. Luceri, E. Bigagli, A. P. Femia, G. Caderni +2 more
2017Toxicology Reports82 citations Open access
Semantic Scholar
Astragali radix: could it be an adjuvant for oxaliplatin-induced neuropathy?
L. di Cesare Mannelli, A. Pacini, L. Micheli, A. P. Femia +9 more
2017Scientific Reports74 citations Open access
Semantic Scholar
Frequent mutation of Apc gene in rat colon tumors and mucin-depleted foci, preneoplastic lesions in experimental colon carcinogenesis.
A. P. Femia, P. Dolara, A. Giannini, M. Salvadori +2 more
2007Cancer Research69 citations
Semantic Scholar
Mucin‐depleted foci have β‐catenin gene mutations, altered expression of its protein, and are dose‐ and time‐dependent in the colon of 1,2‐dimethylhydrazine‐treated rats
A. P. Femia, B. Bendinelli, A. Giannini, M. Salvadori +3 more
2005International Journal of Cancer61 citations
Semantic Scholar
Arabinoxylan-oligosaccharides (AXOS) reduce preneoplastic lesions in the colon of rats treated with 1,2-dimethylhydrazine (DMH)
A. P. Femia, M. Salvadori, W. Broekaert, I. François +3 more
2010European Journal of Nutrition58 citations Open access
Semantic Scholar
Rodent Models of Colon Carcinogenesis for the Study of Chemopreventive Activity of Natural Products
A. P. Femia, G. Caderni
2008Planta Medica58 citations Open access
Semantic Scholar
Long‐term treatment with Sitagliptin, a dipeptidyl peptidase‐4 inhibitor, reduces colon carcinogenesis and reactive oxygen species in 1,2‐dimethylhydrazine‐induced rats
A. P. Femia, L. Raimondi, Giulia Maglieri, M. Lodovici +2 more
2013International Journal of Cancer57 citations Open access
Semantic Scholar
A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apcam1137)
M. Navarra, A. P. Femia, A. Romagnoli, Katia Tortora +4 more
2019European Journal of Nutrition54 citations
Semantic Scholar
Reduction of colonic inflammation in HLA-B27 transgenic rats by feeding Marie Ménard apples, rich in polyphenols†
C. Castagnini, C. Luceri, S. Toti, E. Bigagli +15 more
2009British Journal of Nutrition54 citations Open access
Semantic Scholar
Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats
A. P. Femia, C. Luceri, S. Toti, A. Giannini +2 more
2010BMC Cancer48 citations Open access
Semantic Scholar
Identification of Mucin Depleted Foci in the Human Colon
A. P. Femia, A. Giannini, M. Fazi, E. Tarquini +5 more
2008Cancer Prevention Research48 citations
Semantic Scholar
Pomegranate By‐Products in Colorectal Cancer Chemoprevention: Effects in Apc‐Mutated Pirc Rats and Mechanistic Studies In Vitro and Ex Vivo
Katia Tortora, A. P. Femia, A. Romagnoli, Irene Sineo +4 more
2018Molecular Nutrition & Food Research38 citations Open access
Semantic Scholar
K‐ras mutations and mucin profile in preneoplastic lesions and colon tumors induced in rats by 1,2‐dimethylhydrazine
A. P. Femia, E. Tarquini, M. Salvadori, S. Ferri +3 more
2008International Journal of Cancer32 citations Open access
Semantic Scholar
Mucin‐depleted foci show strong activation of inflammatory markers in 1,2‐dimethylhydrazine‐induced carcinogenesis and are promoted by the inflammatory agent sodium dextran sulfate
A. P. Femia, P. Dolara, C. Luceri, M. Salvadori +1 more
2009International Journal of Cancer30 citations Open access
Semantic Scholar
Sulindac, 3,3’-diindolylmethane and curcumin reduce carcinogenesis in the Pirc rat, an Apc-driven model of colon carcinogenesis
A. P. Femia, Paulo Victória Soares, C. Luceri, M. Lodovici +2 more
2015BMC Cancer29 citations Open access
Semantic Scholar
Effect of polyphenolic extracts from red wine and 4–OH–coumaric acid on 1,2–dimethylhydrazine–induced colon carcinogenesis in rats
A. P. Femia, G. Caderni, F. Vignali, M. Salvadori +6 more
2005European Journal of Nutrition28 citations
Semantic Scholar
Effect of diets fortified with tomatoes or onions with variable quercetin-glycoside content on azoxymethane-induced aberrant crypt foci in the colon of rats
A. P. Femia, G. Caderni, Maura Ianni, M. Salvadori +4 more
2003European Journal of Nutrition28 citations Open access
Semantic Scholar
Multiple mucin depleted foci, high proliferation and low apoptotic response in the onset of colon carcinogenesis of the PIRC rat, mutated in Apc
A. P. Femia, C. Luceri, Paulo Victória Soares, M. Lodovici +1 more
2015International Journal of Cancer26 citations Open access
Semantic Scholar
Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin
A. P. Femia, P. Dolara, M. Salvadori, G. Caderni
2013BMC Cancer23 citations Open access
Semantic Scholar
Marie Ménard apples with high polyphenol content and a low-fat diet reduce 1,2-dimethylhydrazine-induced colon carcinogenesis in rats: effects on inflammation and apoptosis.
A. P. Femia, C. Luceri, F. Bianchini, M. Salvadori +5 more
2012Molecular Nutrition & Food Research23 citations
Semantic Scholar
Characterization of hERG1 channel role in mouse colorectal carcinogenesis
A. Fiore, L. Carraresi, A. Morabito, S. Polvani +6 more
2013Cancer Medicine19 citations Open access
Semantic Scholar
Morin‐dependent inhibition of low molecular weight protein tyrosine phosphatase (LMW‐PTP) restores sensitivity to apoptosis during colon carcinogenesis: Studies in vitro and in vivo, in an Apc‐driven model of colon cancer
Giulia Lori, P. Paoli, A. P. Femia, E. Pranzini +5 more
2019Molecular Carcinogenesis17 citations
Semantic Scholar
Sustained proliferation and resistance to apoptosis after a cytotoxic insult are early alterations in rat colon carcinogenesis
A. P. Femia, F. Salvianti, C. Luceri, P. Dolara +3 more
2012International Journal of Cancer13 citations Open access
Semantic Scholar
No effects of olive oils with different phenolic content compared to corn oil on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats
A. P. Femia, P. Dolara, M. Servili, S. Esposto +5 more
2008European Journal of Nutrition12 citations
Semantic Scholar
Mucin‐depleted foci are modulated by dietary treatments and show deregulation of proliferative activity in carcinogen‐treated rodents
A. P. Femia, G. Caderni, C. Bottini, M. Salvadori +2 more
2007International Journal of Cancer12 citations Open access
Semantic Scholar
Correspondence between flat aberrant crypt foci and mucin-depleted foci in rodent colon carcinogenesis.
A. P. Femia, J. Paulsen, P. Dolara, J. Alexander +1 more
2008Anticancer Research10 citations
Semantic Scholar
Supplementation with phytoestrogens and insoluble fibers reduces intestinal carcinogenesis and restores ER-β expression in Apc-driven colorectal carcinogenesis.
C. Luceri, A. P. Femia, Katia Tortora, Mario D’Ambrosio +3 more
2019European Journal of Cancer Prevention9 citations
Semantic Scholar
Mucin Depleted Foci, Colonic Preneoplastic Lesions Lacking Muc2, Show Up-Regulation of Tlr2 but Not Bacterial Infiltration
A. P. Femia, A. Swidsinski, P. Dolara, M. Salvadori +2 more
2012PLoS ONE8 citations Open access
Semantic Scholar
Risk factors for colorectal cancer in man induce aberrant crypt foci in rats: Preliminary findings
Kai Yang, Sara Fard, R. Furrer, M. C. Archer +10 more
2015Nutrition and Cancer7 citations Open access
Semantic Scholar
High Sensitivity to Cholic Acid-induced Colonic Tumorigenesis Makes Female PIRC Rats (F344/NTac-Apcam1137) a Suitable Model for Studying CRC-promoting Agents
C. Luceri, A. P. Femia, Mario D’Ambrosio, G. Caderni
2019Anticancer Research6 citations Open access
Semantic Scholar
Apc‐driven colon carcinogenesis in pirc rat is strongly reduced by polyethylene glycol
A. P. Femia, C. Becherucci, S. Crucitta, G. Caderni
2015International Journal of Cancer6 citations Open access
Semantic Scholar
ISRm31, a new insertion sequence of the IS66 family in Sinorhizobium meliloti
E. Biondi, A. P. Femia, F. Favilli, M. Bazzicalupo
2003Archives of Microbiology5 citations
Semantic Scholar
Low intestinal tract adenomatous polyps regression in FAP patients by dietary-induced erbeta upregulatior
F. Tonelli, Sergio Fabbri, Ferdinando Ficari, G. Batignani +3 more
20183 citations
Semantic Scholar
Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin
A. P. Femia, P. Dolara, M. Salvadori, G. Caderni
2013BMC Cancer3 citations Open access
Semantic Scholar
Gene Expression Profile of Colon Mucosa after Cytotoxic Insult in wt and Apc-Mutated Pirc Rats: Possible Relation to Resistance to Apoptosis during Carcinogenesis
A. P. Femia, C. Luceri, M. Lodovici, S. Crucitta +1 more
2016BioMed Research International2 citations Open access
Semantic Scholar
Retraction Note: Astragali radix: could it be an adjuvant for oxaliplatin-induced neuropathy?
L. di Cesare Mannelli, A. Pacini, L. Micheli, A. P. Femia +9 more
2023Scientific Reports0 citations Open access
Semantic Scholar
POMEGRANATE BY-PRODUCTS AS A SOURCE OF POLYPHENOLS AND FIBERS: POTENTIAL COLORECTAL CANCER CHEMOPREVENTIVE ACTIVITY OF A MESOCARP DECOCTION
Katia Tortora, A. P. Femia, Irene Sineo, Mohamad Khatib +3 more
20170 citations
Semantic Scholar
INHIBITION OF SPONTANEOUS COLON TUMORIGENESIS IN PIRC RATS (F344/NTAC-APC AM1137), MUTATED IN APC, AND MECHANISTIC STUDIES IN VITRO AND EX-VIVO, SUGGEST POTENTIAL CHEMIOPREVENTIVE ACTIVITY OF A POMEGRANATE MESOCARP PREPARATION.
Katia Tortora, A. P. Femia, A. Romagnoli, Mohamad Khatib +4 more
20170 citations
Semantic Scholar
Prebiotic treatment modulates the gut-associated immune system and decreases AOM-induced carcinogesis in F344 rats
M. Roller, A. P. Femia, J. V. Van Loo, G. Caderni +2 more
20030 citations
Semantic Scholar
Carcinogenesis Colon of Azoxymethane-treated Rats : Correlation with Identification of Mucin-depleted Foci in the Unsectioned Updated Version
G. Caderni, A. P. Femia, A. Giannini, Alessandro Favuzza +3 more
20030 citations
Semantic Scholar

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G. Caderni×45
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G. Caderni — researcher profile on SciRah
P. Dolara×22
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P. Dolara — researcher profile on SciRah
M. Salvadori×19
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M. Salvadori — researcher profile on SciRah
C. Luceri×18
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C. Luceri — researcher profile on SciRah

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A. Giannini — researcher profile on SciRah

L. Giovannelli×6

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L. Giovannelli — researcher profile on SciRah

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M. Lodovici — researcher profile on SciRah

Katia Tortora×6

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Katia Tortora — researcher profile on SciRah

A. Romagnoli×4

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A. Romagnoli — researcher profile on SciRah

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M. Fazi — researcher profile on SciRah

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F. Tonelli — researcher profile on SciRah

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P. Pinzani — researcher profile on SciRah