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R. Grosschedl · SciRah

Researcher profile · Semantic Scholar

R. Grosschedl

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R. Grosschedl — researcher profile on SciRah

h-index: 77
Works: 173
Citations: 27K

Most-cited papers

Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma
J. Okosun, C. Bödör, Jun Wang, Shamzah Araf +30 more
2013Nature Genetics813 citations Open access
Semantic Scholar
SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation.
G. Dobreva, Maria H. Chahrour, M. Dautzenberg, Laura Chirivella +4 more
2006Cell549 citations Open access
Semantic Scholar
Dynamics and interplay of nuclear architecture, genome organization, and gene expression.
Robert Schneider, R. Grosschedl
2007Genes & Development435 citations Open access
Semantic Scholar
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.
M. Dawlaty, Liviu A. Malureanu, Karthik B. Jeganathan, E. Kao +5 more
2008Cell317 citations Open access
Semantic Scholar
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
J. Pongubala, Daniel L. Northrup, D. Lancki, K. Medina +6 more
2008Nature Immunology270 citations
Semantic Scholar
Assembling a gene regulatory network for specification of the B cell fate.
K. Medina, J. Pongubala, K. Reddy, D. Lancki +4 more
2004Developmental Cell255 citations Open access
Semantic Scholar
Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin.
T. Treiber, Elizabeth M. Mandel, Sebastian Pott, I. Győry +3 more
2010Immunity237 citations Open access
Semantic Scholar
miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2
Jian-Wen Wei, Yu Shi, Li-Hua Zheng, Bin Zhou +5 more
2012Journal of Cell Biology226 citations Open access
Semantic Scholar
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
J. Skokowa, G. Cario, Murat Uenalan, A. Schambach +10 more
2006Nature Medicine206 citations Open access
Semantic Scholar
LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis.
Juan Galceran, C. Sustmann, Shu-Chi Hsu, S. Folberth +1 more
2004Genes & Development205 citations Open access
Semantic Scholar
Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells
Robert Nechanitzky, Duygu Akbas, S. Scherer, I. Győry +4 more
2013Nature Immunology202 citations
Semantic Scholar
Distinct Promoters Mediate the Regulation of Ebf1 Gene Expression by Interleukin-7 and Pax5
S. Roessler, I. Győry, Sascha Imhof, Mikhail Spivakov +4 more
2006Molecular and Cellular Biology192 citations Open access
Semantic Scholar
A network of genetic repression and derepression specifies projection fates in the developing neocortex
Karpagam Srinivasan, Dino P. Leone, Rosalie K Bateson, G. Dobreva +4 more
2012Proceedings of the National Academy of Sciences of the United States of America185 citations Open access
Semantic Scholar
Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis
C. Kokubu, U. Heinzmann, T. Kokubu, Norio Sakai +7 more
2004Development185 citations Open access
Semantic Scholar
The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis.
Oliver Bischof, K. Schwamborn, Nadine Martin, A. Werner +3 more
2006Molecules and Cells174 citations Open access
Semantic Scholar
Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex.
Dino P. Leone, Whitney E. Heavner, Emily Ferenczi, G. Dobreva +3 more
2015Cerebral Cortex160 citations Open access
Semantic Scholar
Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells.
I. Győry, S. Boller, Robert Nechanitzky, Elizabeth M. Mandel +3 more
2012Genes & Development158 citations Open access
Semantic Scholar
Wnt signaling interacts with Shh to regulate taste papilla development
K. Iwatsuki, Hong-Xiang Liu, Albert Grónder, Meredith A. Singer +4 more
2007Proceedings of the National Academy of Sciences of the United States of America151 citations Open access
Semantic Scholar
Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression.
F. Savarese, Amparo Dávila, Robert Nechanitzky, I. A. de la Rosa-Velázquez +7 more
2009Genes & Development144 citations Open access
Semantic Scholar
Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland.
Kata Boras-Granic, Hong Chang, R. Grosschedl, P. Hamel
2006Developmental Biology142 citations Open access
Semantic Scholar
Hindgut defects and transformation of the gastro‐intestinal tract in Tcf4−/−/Tcf1−/− embryos
A. Gregorieff, R. Grosschedl, H. Clevers
2004EMBO Journal132 citations Open access
Semantic Scholar
Transcription control of early B cell differentiation.
Elizabeth M. Mandel, R. Grosschedl
2010Current Opinion in Immunology131 citations
Semantic Scholar
LEF1 is a critical epithelial survival factor during tooth morphogenesis.
Tomoyo Sasaki, Yoshihiro Ito, Xun Xu, Jun Han +5 more
2005Developmental Biology127 citations Open access
Semantic Scholar
EBF2 regulates osteoblast-dependent differentiation of osteoclasts.
M. Kieslinger, S. Folberth, G. Dobreva, T. Dorn +4 more
2005Developmental Cell125 citations Open access
Semantic Scholar
Mzb1 Protein Regulates Calcium Homeostasis, Antibody Secretion, and Integrin Activation in Innate-like B Cells
Henrik Flach, M. Rosenbaum, M. Duchniewicz, Sola Kim +4 more
2010Immunity124 citations Open access
Semantic Scholar
MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress
M. Rosenbaum, Virginia Andreani, Tanya Kapoor, Simone Herp +3 more
2014Genes & Development120 citations Open access
Semantic Scholar
Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming.
S. Boller, Senthilkumar Ramamoorthy, Duygu Akbas, Robert Nechanitzky +4 more
2016Immunity118 citations Open access
Semantic Scholar
The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function
S. Boller, R. Grosschedl
2014Immunological Reviews117 citations Open access
Semantic Scholar
Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice
H. Yanai, S. Chiba, S. Hangai, K. Kometani +10 more
2018Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
Roles of SATB2 in Osteogenic Differentiation and Bone Regeneration
Jin Zhang, Q. Tu, R. Grosschedl, Min Seok Kim +4 more
2011Tissue Engineering. Part A95 citations Open access
Semantic Scholar
PIASy-Deficient Mice Display Modest Defects in IFN and Wnt Signaling1
Wera Roth, C. Sustmann, M. Kieslinger, Andrea Gilmozzi +4 more
2004Journal of Immunology92 citations Open access
Semantic Scholar
Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF–triggered granulopoiesis
J. Skokowa, M. Klimiankou, O. Klimenkova, D. Lan +12 more
2012Nature Medicine86 citations Open access
Semantic Scholar
Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming
Rui Li, P. Cauchy, Senthilkumar Ramamoorthy, S. Boller +2 more
2018Genes & Development81 citations Open access
Semantic Scholar
Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function
Virginia Andreani, Senthilkumar Ramamoorthy, Abhinav Pandey, Ekaterina Lupar +3 more
2018Proceedings of the National Academy of Sciences of the United States of America70 citations Open access
Semantic Scholar
A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin.
Yuanting Wang, N. Zolotarev, Cheng-Yuan Yang, Angelika S. Rambold +2 more
2020Immunity67 citations Open access
Semantic Scholar
Cell-Type-Specific Function of BCL9 Involves a Transcriptional Activation Domain That Synergizes with β-Catenin
C. Sustmann, Henrik Flach, Hanna Ebert, Q. Eastman +1 more
2008Molecular and Cellular Biology57 citations Open access
Semantic Scholar
Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner.
M. Kieslinger, Silvia Hiechinger, G. Dobreva, G. Consalez +1 more
2010Cell Stem Cell56 citations Open access
Semantic Scholar
Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins.
N. Treiber, T. Treiber, G. Zocher, R. Grosschedl
2010Genes & Development54 citations Open access
Semantic Scholar
DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity
Roshni Roy, Senthilkumar Ramamoorthy, Benjamin D. Shapiro, M. Kaileh +26 more
2021Immunity49 citations Open access
Semantic Scholar
Sensory map transfer to the neocortex relies on pretarget ordering of thalamic axons.
Ludmilla Lokmane, Rémi D. Proville, N. Narboux-Nême, I. Győry +6 more
2013Current Biology45 citations Open access
Semantic Scholar
Defining B Cell Chromatin: Lessons from EBF1.
S. Boller, Rui Li, R. Grosschedl
2018Trends in Genetics44 citations
Semantic Scholar
Satb2 is required for the development of a spinal exteroceptive microcircuit that modulates limb position
Kathryn L. Hilde, Ariel J. Levine, C. Hinckley, M. Hayashi +7 more
2016Neuron44 citations Open access
Semantic Scholar
Active intermixing of indirect and direct neurons builds the striatal mosaic
Andrea Tinterri, Fabien Menardy, M. Diana, Ludmilla Lokmane +11 more
2018Nature Communications39 citations Open access
Semantic Scholar
PIAS proteins as repressors of Oct4 function.
E. Tolkunova, Anna Malashicheva, V. Parfenov, C. Sustmann +2 more
2007Journal of Molecular Biology36 citations
Semantic Scholar
EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential
Marta Derecka, J. Herman, P. Cauchy, Senthilkumar Ramamoorthy +3 more
2020Nature Immunology34 citations Open access
Semantic Scholar
Satb 2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex
Dino P. Leone, Whitney E. Heavner, Emily Ferenczi, G. Dobreva +3 more
201434 citations
Semantic Scholar
Comprehensive Proteomic Investigation of Ebf1 Heterozygosity in Pro-B Lymphocytes Utilizing Data Independent Acquisition.
Y. Musa, S. Boller, M. Puchalska, R. Grosschedl +1 more
2018Journal of Proteome Research32 citations
Semantic Scholar
The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription
A. Rodríguez-Gil, Olesja Ritter, Vera V. Saul, J. Wilhelm +6 more
2017Scientific Reports32 citations Open access
Semantic Scholar
Interaction of CCR4–NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis
Cheng-Yuan Yang, Senthilkumar Ramamoorthy, S. Boller, M. Rosenbaum +5 more
2016Genes & Development30 citations Open access
Semantic Scholar
MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells
Tanya Kapoor, Mauro Corrado, Erika L. Pearce, E. Pearce +1 more
2020Scientific Reports26 citations Open access
Semantic Scholar

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