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Martina P. Pasillas · SciRah

Researcher profile · Semantic Scholar

Martina P. Pasillas

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Martina P. Pasillas — researcher profile on SciRah

h-index: 23
Works: 42
Citations: 4,952

Most-cited papers

An environment-dependent transcriptional network specifies human microglia identity
D. Gosselin, Dylan Skola, N. Coufal, I. Holtman +13 more
2017Science1,125 citations Open access
Semantic Scholar
Brain cell type-specific enhancer-promoter interactome maps and disease risk association
A. Nott, I. Holtman, N. Coufal, J. Schlachetzki +22 more
2019Science683 citations Open access
Semantic Scholar
NUP98–NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis
G. Wang, Ling Cai, Martina P. Pasillas, M. Kamps
2007Nature Cell Biology462 citations
Semantic Scholar
Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis
J. Seidman, T. Troutman, Mashito Sakai, Anita Gola +19 more
2020Immunity397 citations Open access
Semantic Scholar
Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8
G. Wang, K. Calvo, Martina P. Pasillas, D. Sykes +2 more
2006Nature Methods395 citations
Semantic Scholar
Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain Kupffer cell identity
Mashito Sakai, T. Troutman, J. Seidman, Zhengyu Ouyang +18 more
2019Immunity361 citations Open access
Semantic Scholar
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis
Xiao-Li Sun, J. Seidman, Peng Zhao, T. Troutman +15 more
2019Cell Metabolism179 citations Open access
Semantic Scholar
Hoxa9 Immortalizes a Granulocyte-Macrophage Colony-Stimulating Factor-Dependent Promyelocyte Capable of Biphenotypic Differentiation to Neutrophils or Macrophages, Independent of Enforced Meis Expression
K. Calvo, D. Sykes, Martina P. Pasillas, M. Kamps
2000Molecular and Cellular Biology139 citations Open access
Semantic Scholar
Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus.
G. Wang, Martina P. Pasillas, M. Kamps
2005Blood135 citations Open access
Semantic Scholar
Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1
K. Calvo, D. Sykes, Martina P. Pasillas, M. Kamps
2002Oncogene126 citations
Semantic Scholar
Heterogeneity of hepatic stellate cells in a mouse model of non-alcoholic steatohepatitis (NASH)
S. Rosenthal, Xiao Liu, Souradipta Ganguly, D. Dhar +7 more
2021Hepatology122 citations Open access
Semantic Scholar
Meis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: Potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia
K. Calvo, P. Knoepfler, D. Sykes, Martina P. Pasillas +1 more
2001Proceedings of the National Academy of Sciences of the United States of America110 citations Open access
Semantic Scholar
Persistent Transactivation by Meis1 Replaces Hox Function in Myeloid Leukemogenesis Models: Evidence for Co-Occupancy of Meis1-Pbx and Hox-Pbx Complexes on Promoters of Leukemia-Associated Genes
G. Wang, Martina P. Pasillas, M. Kamps
2006Molecular and Cellular Biology109 citations
Semantic Scholar
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4
Maud Gratuze, J. Schlachetzki, Ricardo D’Oliveira Albanus, Nimansha Jain +14 more
2022Neuron93 citations Open access
Semantic Scholar
SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity
Bethany R. Fixsen, Claudia Z. Han, Yi Zhou, N. Spann +18 more
2023Nature Immunology78 citations Open access
Semantic Scholar
HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation
P. Knoepfler, D. Sykes, Martina P. Pasillas, M. Kamps
2001Oncogene69 citations
Semantic Scholar
Human microglia maturation is underpinned by specific gene regulatory networks
Claudia Z. Han, Rick Z. Li, E. Hansen, S. Trescott +32 more
2023Immunity65 citations Open access
Semantic Scholar
NSD1 PHD domains bind methylated H3K4 and H3K9 using interactions disrupted by point mutations in human sotos syndrome
Martina P. Pasillas, Meera Shah, M. Kamps
2011Human Mutation55 citations Open access
Semantic Scholar
Somatic Mosaicism Reveals Clonal Distributions of Neocortical Development
Martin W. Breuss, Xiaoxu Yang, J. Schlachetzki, D. Antaki +21 more
2022Nature52 citations Open access
Semantic Scholar
Proteomic Analysis Reveals a Role for Bcl2-associated Athanogene 3 and Major Vault Protein in Resistance to Apoptosis in Senescent Cells by Regulating ERK1/2 Activation*
Martina P. Pasillas, Sarah-Kim Shields, Rebecca Reilly, J. Strnádel +6 more
2014Molecular & Cellular Proteomics37 citations Open access
Semantic Scholar
EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1
Xin-Yu Fu, S. Mcgrath, Martina P. Pasillas, S. Nakazawa +1 more
1999Oncogene37 citations
Semantic Scholar
Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism
Tania Manchenkov, Martina P. Pasillas, G. Haddad, Farhad B. Imam
2015G3: Genes, Genomes, Genetics33 citations Open access
Semantic Scholar
Transcriptional Profiling During the Early Differentiation of Granulocyte and Monocyte Progenitors Controlled by Conditional Versions of the E2a–Pbx1 Oncoprotein
D. Sykes, J. Scheele, Martina P. Pasillas, M. Kamps
2003Leukemia and Lymphoma27 citations
Semantic Scholar
Procedures for the biochemical enrichment and proteomic analysis of the cytoskeletome
Sunkyu Choi, J. Kelber, Xin-Ning Jiang, J. Strnádel +4 more
2013Analytical Biochemistry19 citations Open access
Semantic Scholar
Somatic mosaicism in the mature brain reveals clonal cellular distributions during cortical development
Martin W. Breuss, Xiaoxu Yang, D. Antaki, J. Schlachetzki +16 more
2020bioRxiv16 citations Open access
Semantic Scholar
Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes
Hunter R. Bennett, T. Troutman, Enchen Zhou, N. Spann +11 more
2023Nature Immunology15 citations Open access
Semantic Scholar
Cell type-specific enhancer-promoter connectivity maps in the human brain and disease risk association
A. Nott, I. Holtman, N. Coufal, J. Schlachetzki +21 more
201911 citations Open access
Semantic Scholar
Decreased transcript expression coincident with impaired glycosylation in the beta2-adrenergic receptor gene does not result from differences in the primary sequence.
Richard J. Hughes, Martina P. Pasillas, J. Sáiz, Jeffrey R. Jasper +1 more
1997Biochimica et Biophysica Acta7 citations Open access
Semantic Scholar
Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model
Christopher D. Balak, J. Schlachetzki, Addison J. Lana, Elizabeth West +13 more
2024bioRxiv4 citations Open access
Semantic Scholar
Lysosomal dysfunction drives a transcriptional and epigenetic signature characteristic of disease-associated microglia in neurodegenerative diseases
Christopher D. Balak, J. Schlachetzki, Addison J. Lana, Elizabeth West +17 more
2026Immunity1 citations Open access
Semantic Scholar
Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in NASH
J. Seidman, T. Troutman, Mashito Sakai, Anita Gola +19 more
2020Social Science Research Network1 citations
Semantic Scholar
Design and Fabrication of a Micro Electro Discharge Machining System
J. Cole, Salem Alzofiri, V. Gallardo, Martina P. Pasillas +1 more
20171 citations
Semantic Scholar
Cell type-specific histone acetylation landscape in Alzheimer’s disease reveals a putative role of MITF in microglia
Charbel Gergian, Paulina Urbanaviciute, Philippa M. Wells, J. Transfeld +14 more
2026bioRxiv0 citations Open access
Semantic Scholar
Systematic analysis of transcriptional and epigenetic effects of genetic variation in Kupffer cells enables discrimination of cell intrinsic and environment-dependent mechanisms
Hunter R. Bennett, T. Troutman, E. Zhou, N. Spann +11 more
2022bioRxiv0 citations Open access
Semantic Scholar
264 Interrogating altered enhancer landscapes to decode pathogenic changes in macrophages during chronic inflammatory disease
J. Seidman, T. Troutman, Mashito Sakai, R. Li +10 more
20200 citations Open access
Semantic Scholar
Exploiting altered enhancer landscapes to decode pathogenic changes in gene expression of diverse hepatic macrophages
T. Troutman, J. Seidman, Mashito Sakai, Anita Gola +11 more
2019Journal of Immunology0 citations
Semantic Scholar
Deciphering liver environmental signaling pathways for Kupffer cell identity
Mashito Sakai, T. Troutman, J. Seidman, Zhengyu Ouyang +14 more
2019Journal of Immunology0 citations
Semantic Scholar
Hepatic Myeloid Cell Diversity During Fibrosis and Nonalcoholic Steatohepatitis
T. Troutman, J. Seidman, Verena M. Link, M. Hosseini +5 more
2018Journal of Immunology0 citations
Semantic Scholar
Title Novel genes critical for hypoxic preconditioning in zebrafish are regulators of insulin and glucose metabolism
Tania Manchenkov, Martina P. Pasillas, G. Haddad, Farhad B. Imam
20150 citations
Semantic Scholar
Abstract LB-18: Bcl2-associated athanogene 3 and major vault protein regulate cell survival and resistance to apoptosis in senescent cells by regulating ERK activation
Martina P. Pasillas, Sarah-Kim Shields, Rebecca Reilly, L. Mulrane +6 more
20140 citations
Semantic Scholar
of the Meis1 C-terminus using a mechanism that requires interaction with PBX and a novel function Meis1 programs transcription of FLT3 and cancer stem cell character,
G. Wang, Martina P. Pasillas, M. Kamps
20130 citations
Semantic Scholar
Fusion to Vp16 Converts MEIS1 into an Oncoprotein That Immortalizes Progenitors and Causes AML in the Absence of Coexpressed Hox Genes: Hoxa7 and Hoxa9 Induced Further Stem Cell Gene Transcription in Vp16MEIS1 Progenitors.
G. Wang, Martina P. Pasillas, M. Kamps
20050 citations
Semantic Scholar

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N. Spann×13
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J. Schlachetzki×11
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T. Troutman — researcher profile on SciRah

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Mashito Sakai×10

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Hunter R. Bennett×9

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Cassi M. Bruni×7

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D. Gosselin — researcher profile on SciRah