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Y. Ozawa · SciRah

Researcher profile · Semantic Scholar

Y. Ozawa

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Y. Ozawa — researcher profile on SciRah

h-index: 14
Works: 83
Citations: 2,051

Most-cited papers

Lenvatinib plus anti-PD-1 antibody combination treatment activates CD8+ T cells through reduction of tumor-associated macrophage and activation of the interferon pathway
Yu Kato, Kimiyo Tabata, Takayuki Kimura, Ayako Yachie-Kinoshita +12 more
2019PLoS ONE434 citations Open access
Semantic Scholar
Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to mesenchymal–epithelial transition (MET) states
Taku Yoshida, Y. Ozawa, Takayuki Kimura, Yoshiaki Sato +7 more
2014British Journal of Cancer339 citations Open access
Semantic Scholar
Immunomodulatory activity of lenvatinib contributes to antitumor activity in the Hepa1‐6 hepatocellular carcinoma model
Takayuki Kimura, Yu Kato, Y. Ozawa, Kotaro Kodama +9 more
2018Cancer Science313 citations Open access
Semantic Scholar
Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models
Y. Funahashi, Kiyoshi Okamoto, Y. Adachi, T. Semba +14 more
2014Cancer Science255 citations Open access
Semantic Scholar
Inhibition of FGFR Reactivates IFNγ Signaling in Tumor Cells to Enhance the Combined Antitumor Activity of Lenvatinib with Anti-PD-1 Antibodies
Y. Adachi, H. Kamiyama, Kenji Ichikawa, S. Fukushima +10 more
2021Cancer Research146 citations Open access
Semantic Scholar
Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium.
Y. Funahashi, N. Sugi, T. Semba, Yuji Yamamoto +14 more
2002Cancer Research110 citations
Semantic Scholar
Targeting of tumor growth and angiogenesis underlies the enhanced antitumor activity of lenvatinib in combination with everolimus
M. Matsuki, Y. Adachi, Y. Ozawa, Takayuki Kimura +7 more
2017Cancer Science65 citations Open access
Semantic Scholar
E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling
K. Yamada, Yusaku Hori, Satoshi Inoue, Yuji Yamamoto +29 more
2021Cancer Research54 citations
Semantic Scholar
Therapeutic potential and molecular mechanism of a novel sulfonamide anticancer drug, indisulam (E7070) in combination with CPT-11 for cancer treatment
Y. Ozawa, Kazutomi Kusano, T. Owa, A. Yokoi +2 more
2012Cancer Chemotherapy and Pharmacology54 citations
Semantic Scholar
Functional Characterization of VEGF- and FGF-induced Tumor Blood Vessel Models in Human Cancer Xenografts.
Yusaku Hori, K. Ito, S. Hamamichi, Y. Ozawa +3 more
2017Anticancer Research33 citations Open access
Semantic Scholar
Miscibility studies on blends of Kraton block copolymer and asphalt
R. Varma, H. Takeichi, James E. Hall, Y. Ozawa +1 more
200232 citations
Semantic Scholar
Prolonged Intake of Dietary Fermented Isoflavone-Rich Soybean Reinforced with Zinc Affects Circulating Bone Biochemical Markers in Aged Individuals
M. Yamaguchi, A. Igarashi, M. Sakai, Hideyuki Degawa +1 more
200521 citations Open access
Semantic Scholar
Utilization of the synthetic juvenile hormone analog to the silkworm rearing on mulberry leaves
Akiyoshi Muroga, M. Nakajima, Soji Aomori, Y. Ozawa +1 more
197516 citations
Semantic Scholar
Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody
Yuki Niwa, Keito Adachi, Kimiyo Tabata, Ryoga Ishida +7 more
2023Molecular Cancer Therapeutics14 citations Open access
Semantic Scholar
Chemical Composition of Soybean Oil Extracted from Hypocotyle-Enriched Soybean Raw Material and Its Cholesterol Lowering Effects in Rats
Y. Ozawa, Hitoshi Sato, Akihiro Nakatani, Osamu Mori +4 more
200114 citations Open access
Semantic Scholar
Drug disposition of incadronate, a new bisphosphonate, in rats with bone metastases.
T. Usui, Shiro Tanaka, T. Sonoda, Y. Ozawa +4 more
1997Xenobiotica; the fate of foreign compounds in biological systems11 citations
Semantic Scholar
Seasonal variations in the incidence of pine wilt and infestation by its vector, Monochamus alternatus, near the northern limit of the disease in Japan
Kazumasa Ohta, Kazuhiko Hoshizaki, Katsunori Nakamura, Akihiko Nagaki +5 more
2012Journal of Forest Research10 citations
Semantic Scholar
Corrigendum to ‘E7070, a novel sulphonamide agent with potent antitumour activity in vitro and in vivo’ Eur. J. Cancer 2001, 37, 2275-2282. Y. Ozawa, N.H. Sugi, T. Nagasu, T. Owa, T. Watanabe, N. Koyanagi, H. Yoshino, K. Kitoh, K. Yoshimatsu
Y. Ozawa
20029 citations
Semantic Scholar
Synthesis and Biological Activity of Analogs of the Cecropia Juvenile Hormone with Different Alkyl Substituents at C-7 and C-11
Y. Ozawa, K. Mori, M. Matsui
19739 citations
Semantic Scholar
Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor
Kiyoshi Okamoto, D. Ito, K. Miyazaki, Saori Watanabe +15 more
2011International Journal of Molecular Medicine8 citations Open access
Semantic Scholar
Novel peptides with orally active and long-lasting antihypertensive activity.
T. Morikawa, K. Takada, Terutoshi Kimura, Shumpei Sakakibara +5 more
1984Biochemical and Biophysical Research Communications - BBRC8 citations
Semantic Scholar
Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium
J. Eng, Yu Kato, Y. Adachi, B. Swaminathan +25 more
2024Cancer Research Communications7 citations Open access
Semantic Scholar
Synthesis and biological evaluation of N-(7-indolyl)-3-pyridinesulfonamide derivatives as potent antitumor agents.
T. Owa, H. Yoshino, T. Okauchi, Tadashi Okabe +6 more
2002Bioorganic & Medicinal Chemistry Letters7 citations
Semantic Scholar
Effect of Novel Analogs of the Juvenile Hormone. : I. Effect of Juvenile Hormone Analogs with Different Alkyl Substituents at C-7 and C-11 on the Silkworm, Bombyx mori L. (Lepidoptera : Bombycidae)
Masazumi Nihmura, Soji Aomori, Y. Ozawa, K. Mori +1 more
19747 citations Open access
Semantic Scholar
Synthesis and property of end‐functionalized poly(cis‐1,4‐butadiene) and its application to rubber compound
Y. Ozawa, T. Takata
2019Journal of Applied Polymer Science6 citations
Semantic Scholar
Abstract 5177: E7386 : First-in-class orally active CBP/beta-catenin modulator as an anticancer agent
K. Yamada, Yusaku Hori, Atsumi Yamaguchi, M. Matsuki +22 more
20176 citations
Semantic Scholar
Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors.
S. Nagao, Y. Yamane, S. Funasaka, Keigo Tanaka +9 more
2014Bioorganic & Medicinal Chemistry6 citations Open access
Semantic Scholar
A novel antitumor agent ER-35744, targeting G1 phase II Antitumor activities in vitro and in vivo
N. Sugi, Y. Ozawa, Tatsuo Watanabe, T. Nagasu +4 more
19965 citations
Semantic Scholar
Timely administration of synthetic compounds with the juvenile hormone activity to silkworm larvae reared on an artificial diet
Soji Aomori, Y. Ozawa, Masazumi Nihmura
19775 citations
Semantic Scholar
Synthesis and Juvenile Hormone Activity of Some Terpenoid Phenyl Ethers
Y. Ozawa, K. Mori, M. Matsui
19745 citations
Semantic Scholar
Abstract 4089: Antitumor activity of eribulin in combination with anti-PD1 antibody in a mouse syngeneic breast cancer model
T. Semba, Kimiyo Tabata, Y. Ozawa, S. W. Miyano +2 more
2019Immunology4 citations
Semantic Scholar
420 The combination of Indisulam (E7070) with cisplatin, oxaliplatin and 5-fluorouracil are synergistic in vitro and in vivo
Y. Ozawa, T. Owa, A. Yokoi, K. Yoshimatsu +1 more
20044 citations
Semantic Scholar
427 Identification of response marker genes of the antitumor sulfonamide indisulam (E7070)
T. Owa, Y. Ozawa, A. Yokoi, T. Nagasu +2 more
20044 citations
Semantic Scholar
Synthesis of Isocoumarins Part II
M. Matsui, K. Mori, Y. Ozawa
19664 citations Open access
Semantic Scholar
Anionic Polymerization of Dienes Using Homogeneous Lithium Amide (N-Li) Initiators, and Determination of Polymer-Bound Amines
D. Lawson, D. R. Brumbaugh, M. Stayer, J. Schreffler +5 more
19983 citations
Semantic Scholar
Abstract 2927: Antitumor and antiangiogenesis activities of E7386, an orally active CBP/β-catenin modulator, as a single agent and in combination with lenvatinib in human HCC xenograft models
K. Yamada, Yusaku Hori, H. Kamiyama, Takayuki Kimura +3 more
2018Experimental and Molecular Therapeutics2 citations
Semantic Scholar
Abstract 5176: E7386, an orally active CBP/beta-catenin modulator, effects tumor microenvironment, resulting to the enhancement of antitumor activity of lenvatinib
Y. Ozawa, Yusaku Hori, K. Yamada, Y. Funahashi +3 more
20172 citations
Semantic Scholar
Abstract 3264: Lenvatinib in combination with everolimus demonstrated enhanced antiangiogenesis and antitumor activity in human RCC xenograft models
Y. Adachi, M. Matsuki, Atsumi Yamaguchi, Y. Ozawa +9 more
20162 citations
Semantic Scholar
Abstract A296: Eribulin mesylate suppresses experimental metastasis in the MX-1 human breast cancer model by reversing phenotypic states between epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET).
Taku Yoshida, G. Kuznetsov, Takayuki Kimura, N. Sugi +12 more
20132 citations
Semantic Scholar
Abstract 1413: Eribulin caused re-modeling of tumor vasculature altering gene expression profiling in angiogenesis and Epithelial Mesenchymal Transition (EMT) signaling pathway of host cells within human breast cancer cell (BCC) xenografts in nude mice.
J. Matsui, O. Toyama, M. Ino, T. Semba +14 more
20132 citations
Semantic Scholar
A Focused Compound Library of Novel N‐(7‐Indolyl)benzenesulfonamides for the Discovery of Potent Cell Cycle Inhibitors.
T. Owa, T. Okauchi, K. Yoshimatsu, N. Sugi +6 more
20002 citations
Semantic Scholar
Abstract 5136: Development of a novel gene expression signature that correlates with intratumor microvessel density and antitumor activity of lenvatinib
M. Kuronishi, Y. Ozawa, Takayuki Kimura, Yu Kato
2022Cancer Research1 citations
Semantic Scholar
Abstract 1437: E7386, a CREB binding protein (CBP)/β-catenin interaction inhibitor, suppresses the hypoxic response induced by angiogenesis inhibition in hepatocellular carcinoma models
Mizuki Kimura, Yusaku Hori, M. Kuronishi, Takayuki Kimura +4 more
2021Experimental and Molecular Therapeutics1 citations
Semantic Scholar
Abstract 6637: Inhibition of FGFR signaling by lenvatinib activates tumor interferon gamma signaling pathway and potentiates antitumor activity of anti-PD-1 antibody
Y. Adachi, H. Kamiyama, Kenji Ichikawa, Y. Ozawa +8 more
2020Immunology1 citations
Semantic Scholar
Abstract 5172: E7386, an orally active CBP/beta-catenin modulator, induces T cells infiltration into tumor and enhances antitumor activity of anti-PD-1 mAb in Wnt1 tumor syngeneic mice model
Yusaku Hori, K. Yamada, Yu Kato, Y. Ozawa +6 more
20171 citations
Semantic Scholar
The antitumor activity of lenvatinib (LEN) in combination with everolimus (EVE) in human renal cell carcinoma (RCC) xenograft models is dependent on VEGFR and FGFR signaling
Takayuki Kimura, Y. Adachi, M. Matsuki, Atsumi Yamaguchi +9 more
20161 citations Open access
Semantic Scholar
Abstract 3262: Effects of lenvatinib mesilate in combination with everolimus on VEGF and FGF-driven angiogenesis and tumor growth
K. Mitsuhashi, Takayuki Kimura, Taisuke Hoshi, O. Tohyama +9 more
20161 citations
Semantic Scholar
Abstract 1374: Lenvatinib, tri-specific targeted therapy to VEGFR/FGFR/RET, suppresses angiogenesis through the inhibition of both VEGFR and FGFR signaling pathways
Kenji Ichikawa, S. W. Miyano, Y. Adachi, Yuji Yamamoto +5 more
20151 citations
Semantic Scholar
36 Suppression of metastasis and improvement of drug distribution by eribulin mesylate
Y. Ozawa, Kiyoshi Okamoto, Y. Adachi, M. Asano +3 more
20141 citations
Semantic Scholar
E7107: Antitumor activity on human SCLC and cervical cancer xenografts in relation to its potential predictive markers of response.
Masao Iwata, T. Uenaka, Y. Ozawa, Y. Kotake +2 more
20071 citations
Semantic Scholar

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Y. Funahashi×21
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Y. Funahashi — researcher profile on SciRah
J. Matsui×20
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Takayuki Kimura×12
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Y. Adachi×11
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T. Owa — researcher profile on SciRah

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Yu Kato — researcher profile on SciRah

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Yusaku Hori — researcher profile on SciRah

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M. Matsuki — researcher profile on SciRah

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Kiyoshi Okamoto — researcher profile on SciRah

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A. Yokoi — researcher profile on SciRah

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K. Yamada — researcher profile on SciRah

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K. Nomoto — researcher profile on SciRah