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Masao Iwata · SciRah

Researcher profile · Semantic Scholar

Masao Iwata

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Masao Iwata — researcher profile on SciRah

h-index: 10
Works: 27
Citations: 1,911

Most-cited papers

Splicing factor SF3b as a target of the antitumor natural product pladienolide
Y. Kotake, K. Sagane, T. Owa, Y. Mimori-Kiyosue +5 more
2007Nature Chemical Biology636 citations Open access
Semantic Scholar
Antitumor Activity of Lenvatinib (E7080): An Angiogenesis Inhibitor That Targets Multiple Receptor Tyrosine Kinases in Preclinical Human Thyroid Cancer Models
O. Tohyama, J. Matsui, Kotaro Kodama, N. Hata-Sugi +5 more
2014Journal of Thyroid Research436 citations Open access
Semantic Scholar
Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models.
Kiyoshi Okamoto, Kotaro Kodama, Kazuma Takase, N. Sugi +3 more
2013Cancer Letters272 citations Open access
Semantic Scholar
Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities.
Y. Mizui, Takashi Sakai, Masao Iwata, T. Uenaka +5 more
2004Journal of antibiotics (Tokyo. 1968)179 citations Open access
Semantic Scholar
Biological validation that SF3b is a target of the antitumor macrolide pladienolide
A. Yokoi, Y. Kotake, Kentaro Takahashi, T. Kadowaki +7 more
2011The FEBS Journal164 citations Open access
Semantic Scholar
E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling
K. Yamada, Yusaku Hori, Satoshi Inoue, Yuji Yamamoto +29 more
2021Cancer Research54 citations
Semantic Scholar
High antitumor activity of pladienolide B and its derivative in gastric cancer
Momoko Sato, N. Muguruma, Tadahiko Nakagawa, Koichi Okamoto +11 more
2013Cancer Science50 citations Open access
Semantic Scholar
E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models
Saori Watanabe Miyano, Yuji Yamamoto, Kotaro Kodama, Yukiko Miyajima +18 more
2016Molecular Cancer Therapeutics39 citations Open access
Semantic Scholar
Novel ATP-Competitive MEK Inhibitor E6201 Is Effective against Vemurafenib-Resistant Melanoma Harboring the MEK1-C121S Mutation in a Preclinical Model
Y. Narita, Kiyoshi Okamoto, M. Kawada, Kazuma Takase +5 more
2014Molecular Cancer Therapeutics29 citations Open access
Semantic Scholar
Radiolabeled liposome imaging determines an indication for liposomal anticancer agent in ovarian cancer mouse xenograft models
K. Ito, S. Hamamichi, M. Asano, Yusaku Hori +5 more
2015Cancer Science27 citations Open access
Semantic Scholar
E7107, a new 7-urethane derivative of pladienolide D: Discovery of a novel antitumor agent
J. Niijima, Y. Kotake, R. M. Kanada, M. Nagai +11 more
20049 citations
Semantic Scholar
Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium
J. Eng, Yu Kato, Y. Adachi, B. Swaminathan +25 more
2024Cancer Research Communications7 citations Open access
Semantic Scholar
Abstract 5177: E7386 : First-in-class orally active CBP/beta-catenin modulator as an anticancer agent
K. Yamada, Yusaku Hori, Atsumi Yamaguchi, M. Matsuki +22 more
20176 citations
Semantic Scholar
Abstract 770: E7090: A potent and selective FGFR inhibitor with activity in multiple FGFR-driven cancer models with distinct mechanisms of activation
S. W. Miyano, Yuji Yamamoto, Kotaro Kodama, S. Funasaka +18 more
20152 citations
Semantic Scholar
(111) In-encapsulated liposome-distribution in mouse xenografts of human ovarian cancer.
K. Ito, S. Hamamichi, M. Asano, Yusaku Hori +5 more
2016Cancer Science1 citations Open access
Semantic Scholar
307 Anti-tumor Activities of Lenvatinib Against RET Gene Fusion Driven Tumor Models
Kiyoshi Okamoto, Kotaro Kodama, Kazuma Takase, Kazutaka Nakamoto +5 more
20121 citations
Semantic Scholar
E7107: Antitumor activity on human SCLC and cervical cancer xenografts in relation to its potential predictive markers of response.
Masao Iwata, T. Uenaka, Y. Ozawa, Y. Kotake +2 more
20071 citations
Semantic Scholar
Addition of real-time capability to the Japanese dense GPS Network
Y. Hatanaka, A. Yamagiwa, Masao Iwata, Shigeru Otaki
20041 citations
Semantic Scholar
Correction: Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium
J. Eng, Yu Kato, Y. Adachi, B. Swaminathan +25 more
2025Cancer Research Communications0 citations
Semantic Scholar
Abstract 1485: E7011, a novel anti-angiogenesis inhibitor targeting Notch4 receptor signal pathway
Y. Adachi, Yoshimasa Sakamoto, Youya Nakazawa, Sho Tachino +19 more
2020Tumor Biology0 citations
Semantic Scholar
Abstract 3778: In vitro and in vivo characterization of E7090, a novel and selective FGFR inhibitor, for the treatment of endometrial cancer
S. W. Miyano, Yuji Yamamoto, Kotaro Kodama, N. Sugi +3 more
20160 citations
Semantic Scholar
Abstract 1376: Receptor tyrosine kinase (RTK) signaling pathway in preclinical thyroid cancer models: Antitumor and antiangiogenic activity of lenvatinib to target VEGFR/FGFR/RET
O. Tohyama, J. Matsui, Kotaro Kodama, N. Sugi +5 more
20150 citations
Semantic Scholar
Abstract A289: Novel ATP-competitive MEK inhibitor E6201 is effective against vemurafenib-resistant melanoma harboring the MEK1-C121S mutation.
Y. Narita, Kiyoshi Okamoto, M. Kawada, Kazuma Takase +3 more
20130 citations
Semantic Scholar
平成23年(2011年)東北地方太平洋沖地震に伴う基準点測量成果の改定
洋平檜山, Yohei Hiyama, 敦史山際, A. Yamagiwa +16 more
20110 citations
Semantic Scholar
Procédé pour l'examen d'une action d'un agent anti-cancéreux utilisant un défaut d'épissage en tant que mesure
Yoshiharu Mizui, Naoko Hata, Masao Iwata, Koji Sagane +3 more
20080 citations
Semantic Scholar
Results from the real-time analysis of GEONET
T. Yahagi, T. Yutsudo, Hideki Kojima, Tomomi Amagai +2 more
20050 citations
Semantic Scholar
Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107. Part 3. In vitro and in vivo Antitumor Activities.
Y. Mizui, Takashi Sakai, Masao Iwata, T. Uenaka +5 more
20040 citations
Semantic Scholar

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J. Matsui×11
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J. Matsui — researcher profile on SciRah
Y. Minoshima×11
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Y. Minoshima — researcher profile on SciRah
Kiyoshi Okamoto×10
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Kiyoshi Okamoto — researcher profile on SciRah
Kotaro Kodama×9
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Kotaro Kodama — researcher profile on SciRah

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Y. Funahashi — researcher profile on SciRah

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T. Uenaka — researcher profile on SciRah

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Y. Mizui — researcher profile on SciRah

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N. Sugi — researcher profile on SciRah

Yuji Yamamoto×6

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Yuji Yamamoto — researcher profile on SciRah

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A. Tsuruoka — researcher profile on SciRah

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Y. Ozawa — researcher profile on SciRah

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K. Ito — researcher profile on SciRah