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F. Ziyadeh · SciRah

Researcher profile · Semantic Scholar

F. Ziyadeh

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F. Ziyadeh — researcher profile on SciRah

h-index: 64
Works: 160
Citations: 16K

Most-cited papers

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation.
Xue-Liang Du, D. Edelstein, L. Rossetti, I. Fantus +4 more
2000Proceedings of the National Academy of Sciences of the United States of America1,179 citations Open access
Semantic Scholar
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-β antibody in db/db diabetic mice
F. Ziyadeh, B. B. Hoffman, Dong Cheol Han, M. C. I. la Cruz +5 more
2000954 citations Open access
Semantic Scholar
Leptin and renal disease.
G. Wolf, Sheldon Chen, D. Han, F. Ziyadeh
2002American Journal of Kidney Diseases653 citations
Semantic Scholar
From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy.
G. Wolf, Sheldon Chen, F. Ziyadeh
2005Diabetes594 citations Open access
Semantic Scholar
Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation.
F. Strutz, M. Zeisberg, F. Ziyadeh, Chang-qing Yang +5 more
2002Kidney International498 citations Open access
Semantic Scholar
Molecular mechanisms of diabetic renal hypertrophy.
G. Wolf, F. Ziyadeh
1999Kidney International489 citations Open access
Semantic Scholar
Mediators of Diabetic Renal Disease: The Case for TGF-β as the Major Mediator
F. Ziyadeh
2004440 citations Open access
Semantic Scholar
Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy.
F. Ziyadeh, G. Wolf
2008Current Diabetes Reviews397 citations
Semantic Scholar
Leptin stimulates proliferation and TGF-β expression in renal glomerular endothelial cells: Potential role in glomerulosclerosis1
G. Wolf, A. Hamann, D. Han, U. Helmchen +3 more
1999362 citations Open access
Semantic Scholar
Cellular and Molecular Mechanisms of Proteinuria in Diabetic Nephropathy
G. Wolf, F. Ziyadeh
2007Nephron Physiology271 citations
Semantic Scholar
Diabetic nephropathy and transforming growth factor-beta: transforming our view of glomerulosclerosis and fibrosis build-up.
Sheldon Chen, Belinda Jim, F. Ziyadeh
2003Seminars in Nephrology263 citations
Semantic Scholar
Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice.
S. Sung, F. Ziyadeh, Amy Wang, Petr E. Pyagay +2 more
2006Journal of the American Society of Nephrology215 citations
Semantic Scholar
Mediators of diabetic renal disease: the case for tgf-Beta as the major mediator.
F. Ziyadeh
2004Journal of the American Society of Nephrology204 citations
Semantic Scholar
Leptin and renal fibrosis.
G. Wolf, F. Ziyadeh
2006Contributions to Nephrology186 citations
Semantic Scholar
Captopril-induced reduction of serum levels of transforming growth factor-beta1 correlates with long-term renoprotection in insulin-dependent diabetic patients.
K. Sharma, B. O. Eltayeb, T. Mcgowan, S. Dunn +4 more
1999American Journal of Kidney Diseases166 citations
Semantic Scholar
The urine/plasma electrolyte ratio: a predictive guide to water restriction.
H. Furst, K. Hallows, Jarrod Post, Sheldon Chen +4 more
2000American Journal of the Medical Sciences158 citations
Semantic Scholar
High glucose stimulates proliferation and collagen type I synthesis in renal cortical fibroblasts: mediation by autocrine activation of TGF-beta.
Dong Cheol Han, M. Isono, B. B. Hoffman, F. Ziyadeh
1999Journal of the American Society of Nephrology149 citations
Semantic Scholar
Leptin stimulates proliferation and TGF-beta expression in renal glomerular endothelial cells: potential role in glomerulosclerosis [seecomments].
G. Wolf, A. Hamann, D. C. Han, U. Helmchen +3 more
1999Kidney International145 citations
Semantic Scholar
Reversibility of established diabetic glomerulopathy by anti-TGF-beta antibodies in db/db mice.
Sheldon Chen, M. C. I. la Cruz, Belinda Jim, S. Hong +2 more
2003Biochemical and Biophysical Research Communications - BBRC136 citations Open access
Semantic Scholar
Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells.
M. Isono, M. C. I. la Cruz, Sheldon Chen, S. Hong +1 more
2000Journal of the American Society of Nephrology131 citations
Semantic Scholar
Glycated albumin stimulates TGF-beta 1 production and protein kinase C activity in glomerular endothelial cells.
Sheldon Chen, M. P. Cohen, G. Lautenslager, C. Shearman +1 more
2001Kidney International122 citations Open access
Semantic Scholar
Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria.
Amy Wang, F. Ziyadeh, Eun Young Lee, Petr E. Pyagay +4 more
2007AJP - Renal Physiology118 citations
Semantic Scholar
Therapy with antisense TGF-beta1 oligodeoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice.
Dong Cheol Han, B. B. Hoffman, Soon Won Hong, Jia Guo +1 more
2000AJP - Renal Physiology118 citations Open access
Semantic Scholar
The utility of the transtubular potassium gradient in the evaluation of hyperkalemia.
Michael J. Choi, F. Ziyadeh
2008Journal of the American Society of Nephrology114 citations
Semantic Scholar
Assessment of 115 candidate genes for diabetic nephropathy by transmission/disequilibrium test.
K. Ewens, R. A. George, K. Sharma, F. Ziyadeh +1 more
2005Diabetes111 citations Open access
Semantic Scholar
Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes.
Sheldon Chen, Yuki Kasama, Joseph S. Lee, Belinda Jim +2 more
2004Diabetes105 citations Open access
Semantic Scholar
Angiotensin II stimulates α3(IV) collagen production in mouse podocytes via TGF-β and VEGF signalling: implications for diabetic glomerulopathy
Sheldon Chen, Joseph S. Lee, M. C. I. la Cruz, Amy Wang +5 more
200594 citations Open access
Semantic Scholar
Uremia induces functional incompetence of bone marrow-derived stromal cells.
H. Noh, Mi R. Yu, H. J. Kim, J. Jeon +8 more
2012Nephrology, Dialysis and Transplantation90 citations Open access
Semantic Scholar
Overview: combating diabetic nephropathy.
F. Ziyadeh, K. Sharma
2003Journal of the American Society of Nephrology90 citations Open access
Semantic Scholar
Angiotensin II stimulates expression of transforming growth factor β receptor type II in cultured mouse proximal tubular cells
G. Wolf, F. Ziyadeh, R. Stahl
1999Journal of molecular medicine89 citations
Semantic Scholar
Heat shock protein 90 inhibitor attenuates renal fibrosis through degradation of transforming growth factor-β type II receptor
H. Noh, H. J. Kim, Mi R. Yu, W. Kim +6 more
2012Laboratory Investigation83 citations Open access
Semantic Scholar
Amadori-glycated albumin in diabetic nephropathy: pathophysiologic connections.
Sheldon Chen, M. P. Cohen, F. Ziyadeh
2000Kidney international. Supplement82 citations Open access
Semantic Scholar
Different roles for TGF-beta and VEGF in the pathogenesis of the cardinal features of diabetic nephropathy.
F. Ziyadeh
2008Diabetes Research and Clinical Practice79 citations
Semantic Scholar
Amadori-modified glycated serum proteins and accelerated atherosclerosis in diabetes: pathogenic and therapeutic implications.
M. P. Cohen, F. Ziyadeh, Sheldon Chen
2006Journal of Laboratory and Clinical Medicine75 citations Open access
Semantic Scholar
Albumin up-regulates the type II transforming growth factor-beta receptor in cultured proximal tubular cells.
G. Wolf, R. Schroeder, F. Ziyadeh, R. Stahl
2004Kidney International74 citations Open access
Semantic Scholar
Evidence linking glycated albumin to altered glomerular nephrin and VEGF expression, proteinuria, and diabetic nephropathy.
M. P. Cohen, Sheldon Chen, F. Ziyadeh, Elizabeth A. Shea +3 more
2005Kidney International72 citations Open access
Semantic Scholar
TGF-beta: a crucial component of the pathogenesis of diabetic nephropathy.
S. Goldfarb, F. Ziyadeh
2001Transactions of the American Clinical and Climatological Association72 citations
Semantic Scholar
Glycated albumin stimulation of PKC-β activity is linked to increased collagen IV in mesangial cells.
M. P. Cohen, F. Ziyadeh, G. Lautenslager, J. Cohen +1 more
1999AJP - Renal Physiology66 citations
Semantic Scholar
20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway
Stéphanie A. Eid, Rita Maalouf, A. Jaffa, J. Nassif +4 more
2013PLoS ONE63 citations Open access
Semantic Scholar
Overview of the physiology and pathophysiology of leptin with special emphasis on its role in the kidney.
M. Nasrallah, F. Ziyadeh
2013Seminars in Nephrology60 citations
Semantic Scholar
Retinoids as a potential treatment for experimental puromycin‐induced nephrosis
V. Moreno-Manzano, F. Mampaso, J. C. Sepúlveda-Muñoz, M. Alique +11 more
2003British Journal of Pharmacology60 citations Open access
Semantic Scholar
The cardiorenal syndrome in diabetes mellitus.
H. Karnib, F. Ziyadeh
2010Diabetes Research and Clinical Practice53 citations
Semantic Scholar
Taurine Intestinal Absorption and Renal Excretion Test in Diabetic Patients
M. Merheb, R. Daher, M. Nasrallah, R. Sabra +2 more
2007Diabetes Care52 citations Open access
Semantic Scholar
Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy.
Sheldon Chen, Joseph S. Lee, M. C. I. la Cruz, Amy Wang +5 more
2005Nephrology, Dialysis and Transplantation47 citations
Semantic Scholar
The Renal TGF-β System in the db/db Mouse Model of Diabetic Nephropathy
M. P. Cohen, K. Sharma, Jia Guo, B. O. Eltayeb +1 more
1998Nephron Experimental Nephrology46 citations
Semantic Scholar
Glomerular Hyperfiltration and Proteinuria in Transfusion-Independent Patients with β-Thalassemia Intermedia
F. Ziyadeh, K. Musallam, Naji S. Mallat, S. Mallat +4 more
2012Nephron Clinical Practice44 citations
Semantic Scholar
Differential expression of type IV collagen isoforms in rat glomerular endothelial and mesangial cells.
M. Zeisberg, M. Ericksen, Y. Hamano, E. Neilson +2 more
2002Biochemical and Biophysical Research Communications - BBRC44 citations
Semantic Scholar
Inhibiting Albumin Glycation Ameliorates Diabetic Nephropathy in the db/db Mouse
M. P. Cohen, N. Masson, E. Hud, F. Ziyadeh +2 more
2000Nephron Experimental Nephrology41 citations
Semantic Scholar
Angiotensin II stimulates expression of transforming growth factor beta receptor type II in cultured mouse proximal tubular cells.
G. Wolf, F. Ziyadeh, R. Stahl
1999Journal of molecular medicine41 citations
Semantic Scholar
Leptin stimulates type I collagen production in db/db mesangial cells: glucose uptake and TGF-beta type II receptor expression.
D. C. Han, M. Isono, S. Chen, A. Casaretto +3 more
2001Kidney International35 citations
Semantic Scholar

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Sheldon Chen×16
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Sheldon Chen — researcher profile on SciRah
G. Wolf×14
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M. P. Cohen×7
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M. C. I. la Cruz×6
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D. Han — researcher profile on SciRah

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M. Isono — researcher profile on SciRah

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Amy Wang — researcher profile on SciRah

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K. Sharma — researcher profile on SciRah

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R. Stahl — researcher profile on SciRah

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