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K. Hallows · SciRah

Researcher profile · Semantic Scholar

K. Hallows

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K. Hallows — researcher profile on SciRah

h-index: 44
Works: 135
Citations: 6,192

Most-cited papers

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis
V. Takiar, S. Nishio, Patricia Seo-Mayer, J. D. King +6 more
2011Proceedings of the National Academy of Sciences of the United States of America325 citations Open access
Semantic Scholar
Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin*
Timothy N. Feinstein, Naofumi Yui, M. Webber, V. Wehbi +6 more
2013Journal of Biological Chemistry205 citations Open access
Semantic Scholar
AMPK, a key regulator of metabolism and autophagy, is activated by lysosomal damage via a novel galectin-directed ubiquitin signal transduction system
Jing-Yue Jia, Bhawana Bissa, Lukas Brecht, Lee Allers +8 more
2020Molecules and Cells168 citations Open access
Semantic Scholar
Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors
Zipeng Zeng, Biao Huang, Riana K. Parvez, Yidan Li +13 more
2021Nature Communications113 citations Open access
Semantic Scholar
PKA Regulates Vacuolar H+-ATPase Localization and Activity via Direct Phosphorylation of the A Subunit in Kidney Cells*
R. Alzamora, Ramon F. Thali, F. Gong, Christy Smolak +8 more
2010Journal of Biological Chemistry110 citations Open access
Semantic Scholar
Extracorporeal therapy for dabigatran removal in the treatment of acute bleeding: a single center experience.
T. Singh, T. Maw, Brian L. Henry, N. Pastor-Soler +3 more
2013American Society of Nephrology. Clinical Journal108 citations Open access
Semantic Scholar
AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells.
M. Myerburg, J. D. King, N. Oyster, A. Fitch +6 more
2010American Journal of Respiratory Cell and Molecular Biology106 citations Open access
Semantic Scholar
Vacuolar H+-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase.
F. Gong, R. Alzamora, Christy Smolak, Hui Li +4 more
2010AJP - Renal Physiology103 citations Open access
Semantic Scholar
Septic acute kidney injury: molecular mechanisms and the importance of stratification and targeting therapy
E. Morrell, J. Kellum, N. Pastor-Soler, K. Hallows
2014Critical Care85 citations Open access
Semantic Scholar
Oral Delivery of Metformin by Chitosan Nanoparticles for Polycystic Kidney Disease
Jonathan Wang, Deborah D. Chin, Christopher Poon, V. Mancino +5 more
2020Journal of Controlled Release80 citations Open access
Semantic Scholar
Interactions between HIF-1α and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease.
Hui Li, J. Satriano, Joanna L. Thomas, Satoshi Miyamoto +4 more
2015AJP - Renal Physiology78 citations Open access
Semantic Scholar
Activation of AMP-activated protein kinase (AMPK) during sepsis/inflammation improves survival by preserving cellular metabolic fitness
Kui Jin, Yujie Ma, Carlos L. Manrique-Caballero, Hui Li +15 more
2020The FASEB Journal76 citations Open access
Semantic Scholar
Design and in vivo characterization of kidney-targeting multimodal micelles for renal drug delivery
Jonathan Wang, Christopher Poon, Deborah D. Chin, Sarah Milkowski +3 more
2018Nano Reseach72 citations
Semantic Scholar
Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells.
Hui Li, Ramon F. Thali, Christy Smolak, F. Gong +6 more
2010AJP - Renal Physiology70 citations Open access
Semantic Scholar
Primary results of the randomized trial of metformin administration in polycystic kidney disease (TAME PKD)
R. Perrone, K. Abebe, T. Watnick, A. Althouse +7 more
2021Kidney International69 citations Open access
Semantic Scholar
Role of AMP-activated protein kinase in kidney tubular transport, metabolism, and disease
R. Rajani, N. Pastor-Soler, K. Hallows
2017Current opinion in nephrology and hypertension66 citations
Semantic Scholar
A Randomized Clinical Trial of Metformin to treat Autosomal Dominant Polycystic Kidney Disease
S. Seliger, K. Abebe, K. Hallows, D. Miskulin +3 more
2018American Journal of Nephrology60 citations Open access
Semantic Scholar
Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.
Ankita Roy, Lama Al-Qusairi, Bridget F. Donnelly, Caroline Ronzaud +8 more
2015Journal of Clinical Investigation56 citations Open access
Semantic Scholar
Neural Precursor Cell-expressed Developmentally Down-regulated Protein 4-2 (Nedd4-2) Regulation by 14-3-3 Protein Binding at Canonical Serum and Glucocorticoid Kinase 1 (SGK1) Phosphorylation Sites*
S. Chandran, Hui Li, Wu-Xing Dong, K. Krasinska +5 more
2011Journal of Biological Chemistry54 citations Open access
Semantic Scholar
AMP-activated protein kinase regulates the vacuolar H+-ATPase via direct phosphorylation of the A subunit (ATP6V1A) in the kidney.
R. Alzamora, M. Al-Bataineh, Wen Liu, F. Gong +8 more
2013AJP - Renal Physiology52 citations Open access
Semantic Scholar
Metformin Improves Relevant Disease Parameters in an Autosomal Dominant Polycystic Kidney Disease Mouse Model.
N. Pastor-Soler, Hui Li, Jessica Pham, Daniel Rivera +4 more
2021AJP - Renal Physiology50 citations
Semantic Scholar
AMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells.
R. Alzamora, F. Gong, C. Rondanino, Jeffrey K. Lee +3 more
2010AJP - Renal Physiology50 citations Open access
Semantic Scholar
Long term expandable mouse and human induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
Biao Huang, Zipeng Zeng, Sunghyun Kim, Connor C. Fausto +30 more
2024Cell Stem Cell49 citations Open access
Semantic Scholar
AMP-activated protein kinase regulation of kidney tubular transport
N. Pastor-Soler, K. Hallows
2012Current opinion in nephrology and hypertension49 citations
Semantic Scholar
Phosphopeptide Screen Uncovers Novel Phosphorylation Sites of Nedd4-2 That Potentiate Its Inhibition of the Epithelial Na+ Channel*
K. Hallows, Vivek Bhalla, N. Oyster, M. Wijngaarden +8 more
2010Journal of Biological Chemistry45 citations Open access
Semantic Scholar
AMPK is activated during lysosomal damage via a galectin-ubiquitin signal transduction system.
Jing-Yue Jia, Bhawana Bissa, Lukas Brecht, Lee Allers +8 more
2020Autophagy40 citations Open access
Semantic Scholar
Muc1 is protective during kidney ischemia-reperfusion injury.
N. Pastor-Soler, T. A. Sutton, Henry E. Mang, C. Kinlough +11 more
2015AJP - Renal Physiology40 citations Open access
Semantic Scholar
Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.
C. Rondanino, P. Poland, C. Kinlough, Hui Li +9 more
2011AJP - Renal Physiology40 citations Open access
Semantic Scholar
Epithelial transport during septic acute kidney injury.
E. Morrell, J. Kellum, K. Hallows, N. Pastor-Soler
2014Nephrology, Dialysis and Transplantation34 citations Open access
Semantic Scholar
Renoprotective Effects of Metformin are Independent of Organic Cation Transporters 1 & 2 and AMP-activated Protein Kinase in the Kidney
Michael Christensen, J. Jensen, S. Jakobsen, N. Jessen +7 more
2016Scientific Reports33 citations Open access
Semantic Scholar
Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-activated Protein Kinase
J. D. King, Jeffrey K. Lee, C. Riemen, D. Neumann +5 more
2012Journal of Biological Chemistry32 citations Open access
Semantic Scholar
CFTR regulation by phosphorylation.
R. Alzamora, J. D. King, K. Hallows
2011Methods in molecular biology29 citations
Semantic Scholar
Effects of Hydrochlorothiazide and Metformin on Aquaresis and Nephroprotection by a Vasopressin V2 Receptor Antagonist in ADPKD
B. Kramers, Iris W. Koorevaar, Maatje D. A. van Gastel, H. van Goor +9 more
2022American Society of Nephrology. Clinical Journal27 citations Open access
Semantic Scholar
Akt recruits Dab2 to albumin endocytosis in the proximal tubule.
K. Koral, Hui Li, Nandita Ganesh, M. Birnbaum +2 more
2014AJP - Renal Physiology27 citations Open access
Semantic Scholar
Spatially-patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
Biao Huang, Pedro Medina, Jincan He, Zipeng Zeng +32 more
2025Cell Stem Cell21 citations Open access
Semantic Scholar
Activation of the metabolic sensor AMP-activated protein kinase inhibits aquaporin-2 function in kidney principal cells.
M. Al-Bataineh, Hui Li, K. Ohmi, F. Gong +9 more
2016AJP - Renal Physiology21 citations Open access
Semantic Scholar
AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1.
S. Fraser, S. Choy, N. Pastor-Soler, Hui Li +11 more
2013AJP - Renal Physiology21 citations Open access
Semantic Scholar
Resveratrol Inhibits the Epithelial Sodium Channel via Phopshoinositides and AMP-Activated Protein Kinase in Kidney Collecting Duct Cells
K. Weixel, Allison L. Marciszyn, R. Alzamora, Hui Li +4 more
2013PLoS ONE21 citations Open access
Semantic Scholar
Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats
T. Pavlov, V. Levchenko, D. Ilatovskaya, Hui Li +4 more
2017Frontiers in Physiology18 citations Open access
Semantic Scholar
Association of Longitudinal Urinary Metabolic Biomarkers With ADPKD Severity and Response to Metformin in TAME-PKD Clinical Trial Participants
K. Hallows, K. Abebe, Hui Li, Biagio Saitta +7 more
2022Kidney International Reports16 citations Open access
Semantic Scholar
Investigation of Basolateral Targeting Micelles for Drug Delivery Applications in Polycystic Kidney Disease.
Yi Huang, A. Osouli, Jessica Pham, Valeria Mancino +6 more
2024Biomacromolecules15 citations
Semantic Scholar
Beneficial effects of bempedoic acid treatment in polycystic kidney disease cells and mice
K. Hallows, Hui Li, Biagio Saitta, Saman Sepehr +7 more
2022bioRxiv15 citations Open access
Semantic Scholar
A1 adenosine receptor–stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation
H. S. Prakasam, Luciana I. Gallo, Hui Li, W. Ruiz +2 more
2014Molecular Biology of the Cell15 citations Open access
Semantic Scholar
β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells
Pei-Yin Ho, Hui Li, T. Pavlov, Roland D. Tuerk +5 more
2018Journal of Biological Chemistry14 citations Open access
Semantic Scholar
Female protection against diabetic kidney disease is regulated by kidney-specific AMPK activity.
Hak Joo Lee, Liang Min, Jing-Li Gao, S. Matta +13 more
2024Diabetes13 citations Open access
Semantic Scholar
Baseline Characteristics and Patient-Reported Outcomes of ADPKD Patients in the Multicenter TAME-PKD Clinical Trial
S. Seliger, T. Watnick, A. Althouse, R. Perrone +4 more
2020Kidney36012 citations Open access
Semantic Scholar
Hemodialysis for the Treatment of Severe Accidental Hypothermia
T. Singh, K. Hallows
2014Seminars in dialysis12 citations
Semantic Scholar
Opening lines of communication in the distal nephron.
T. Kleyman, L. Satlin, K. Hallows
2013Journal of Clinical Investigation12 citations Open access
Semantic Scholar
Oral delivery of nanomedicine for genetic kidney disease
Yi Huang, Jonathan Wang, Valeria Mancino, Jessica Pham +10 more
2024PNAS Nexus11 citations Open access
Semantic Scholar
Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cells.
M. Al-Bataineh, R. Alzamora, K. Ohmi, Pei-Yin Ho +5 more
2016AJP - Renal Physiology11 citations Open access
Semantic Scholar

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