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Kenji Funami · SciRah

Researcher profile · Semantic Scholar

Kenji Funami

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Kenji Funami — researcher profile on SciRah

h-index: 32
Works: 59
Citations: 4,706

Most-cited papers

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3–mediated interferon-β induction
H. Oshiumi, M. Matsumoto, Kenji Funami, T. Akazawa +1 more
2003Nature Immunology1,093 citations
Semantic Scholar
Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells
M. Matsumoto, Kenji Funami, M. Tanabe, H. Oshiumi +4 more
2003Journal of Immunology418 citations Open access
Semantic Scholar
Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells 1
M. Matsumoto, Kenji Funami, M. Tanabe, H. Oshiumi +4 more
2003Journal of Immunology412 citations Open access
Semantic Scholar
Toll‐Like Receptor 3: A Link between Toll‐Like Receptor, Interferon and Viruses
M. Matsumoto, Kenji Funami, H. Oshiumi, T. Seya
2004Microbiology and immunology197 citations Open access
Semantic Scholar
The cytoplasmic 'linker region' in Toll-like receptor 3 controls receptor localization and signaling.
Kenji Funami, M. Matsumoto, H. Oshiumi, T. Akazawa +2 more
2004International Immunology191 citations
Semantic Scholar
Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense
Kei-ichiro Arimoto, Kenji Funami, Y. Saeki, Keiji Tanaka +5 more
2010Proceedings of the National Academy of Sciences of the United States of America175 citations Open access
Semantic Scholar
NAK-Associated Protein 1 Participates in Both the TLR3 and the Cytoplasmic Pathways in Type I IFN Induction1
Miwa Sasai, M. Shingai, Kenji Funami, M. Yoneyama +3 more
2006Journal of Immunology157 citations Open access
Semantic Scholar
Infectivity of Hepatitis C Virus Is Influenced by Association with Apolipoprotein E Isoforms
Takayuki Hishiki, Y. Shimizu, Reiri Tobita, K. Sugiyama +9 more
2010Journal of Virology136 citations Open access
Semantic Scholar
Surface-Expressed TLR6 Participates in the Recognition of Diacylated Lipopeptide and Peptidoglycan in Human Cells1
Y. Nakao, Kenji Funami, S. Kikkawa, M. Taniguchi +4 more
2005Journal of Immunology128 citations Open access
Semantic Scholar
Combinational recognition of bacterial lipoproteins and peptidoglycan by chicken Toll-like receptor 2 subfamily.
Megumi Higuchi, A. Matsuo, M. Shingai, K. Shida +6 more
2008Developmental and Comparative Immunology110 citations Open access
Semantic Scholar
The Clathrin-Mediated Endocytic Pathway Participates in dsRNA-Induced IFN-β Production1
K. Itoh, A. Watanabe, Kenji Funami, T. Seya +1 more
2008Journal of Immunology98 citations
Semantic Scholar
Spatiotemporal Mobilization of Toll/IL-1 Receptor Domain-Containing Adaptor Molecule-1 in Response to dsRNA1
Kenji Funami, Miwa Sasai, Y. Ohba, H. Oshiumi +2 more
2007Journal of Immunology98 citations Open access
Semantic Scholar
This information is current as Activation Monoacylated MDP Confers TLR 2 / TLR 4 Muramyl Dipeptide ( MDP ) Derivatives : Dendritic Cell Maturation Induced by Shoichi Kusumoto and Tsukasa Seya
J. Uehori, K. Fukase, T. Akazawa, S. Uematsu +8 more
200587 citations
Semantic Scholar
Hepatitis C Virus Infection Induces Inflammatory Cytokines and Chemokines Mediated by the Cross Talk between Hepatocytes and Stellate Cells
H. Nishitsuji, Kenji Funami, Y. Shimizu, S. Ujino +4 more
2013Journal of Virology86 citations Open access
Semantic Scholar
Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway.
Miwa Sasai, Megumi Tatematsu, H. Oshiumi, Kenji Funami +3 more
2010Molecular Immunology84 citations
Semantic Scholar
Soluble G protein of respiratory syncytial virus inhibits Toll-like receptor 3/4-mediated IFN-beta induction.
M. Shingai, M. Azuma, Takashi Ebihara, Miwa Sasai +6 more
2008International Immunology84 citations Open access
Semantic Scholar
Extracellular RNA Sensing by Pattern Recognition Receptors
Megumi Tatematsu, Kenji Funami, T. Seya, M. Matsumoto
2018Journal of Innate Immunity78 citations Open access
Semantic Scholar
Endosomal Localization of TLR8 Confers Distinctive Proteolytic Processing on Human Myeloid Cells
N. Ishii, Kenji Funami, Megumi Tatematsu, T. Seya +1 more
2014Journal of Immunology74 citations Open access
Semantic Scholar
Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling
Yoshiaki Enokizono, H. Kumeta, Kenji Funami, M. Horiuchi +6 more
2013Proceedings of the National Academy of Sciences of the United States of America74 citations Open access
Semantic Scholar
Cleaved/Associated TLR3 Represents the Primary Form of the Signaling Receptor
F. Toscano, Y. Estornes, François Virard, A. Garcia-Cattaneo +12 more
2013Journal of Immunology72 citations Open access
Semantic Scholar
Hepatitis C virus utilizes lipid droplet for production of infectious virus
Kazuya Ogawa, Takayuki Hishiki, Y. Shimizu, Kenji Funami +3 more
2009Proceedings of the Japan Academy. Series B, Physical and biological sciences69 citations Open access
Semantic Scholar
Homo-oligomerization Is Essential for Toll/Interleukin-1 Receptor Domain-containing Adaptor Molecule-1-mediated NF-κB and Interferon Regulatory Factor-3 Activation*
Kenji Funami, Miwa Sasai, H. Oshiumi, T. Seya +1 more
2008Journal of Biological Chemistry69 citations Open access
Semantic Scholar
UNC93B1 Physically Associates with Human TLR8 and Regulates TLR8-Mediated Signaling
Hiroki Itoh, Megumi Tatematsu, A. Watanabe, Katsunori Iwano +3 more
2011PLoS ONE68 citations Open access
Semantic Scholar
Toll‐like receptor‐mediated tyrosine phosphorylation of paxillin via MyD88‐dependent and ‐independent pathways
K. Hazeki, N. Masuda, Kenji Funami, Naoe Sukenobu +5 more
2003European Journal of Immunology65 citations Open access
Semantic Scholar
Raftlin Controls Lipopolysaccharide-Induced TLR4 Internalization and TICAM-1 Signaling in a Cell Type–Specific Manner
Megumi Tatematsu, Ryuji Yoshida, Yuka Morioka, N. Ishii +5 more
2016Journal of Immunology60 citations Open access
Semantic Scholar
Lipoprotein lipase and hepatic triglyceride lipase reduce the infectivity of hepatitis C virus (HCV) through their catalytic activities on HCV-associated lipoproteins.
Y. Shimizu, Takayuki Hishiki, K. Sugiyama, Kazuya Ogawa +6 more
2010Virology53 citations Open access
Semantic Scholar
Interferon-stimulated gene of 20 kDa protein (ISG20) degrades RNA of hepatitis B virus to impede the replication of HBV in vitro and in vivo
C. Leong, Kenji Funami, H. Oshiumi, Deng Mengao +6 more
2016OncoTarget44 citations Open access
Semantic Scholar
Functional interfaces between TICAM-2/TRAM and TICAM-1/TRIF in TLR4 signaling.
Kenji Funami, M. Matsumoto, H. Oshiumi, F. Inagaki +1 more
2017Biochemical Society Transactions39 citations Open access
Semantic Scholar
C-terminal LRRs of human Toll-like receptor 3 control receptor dimerization and signal transmission.
E. Takada, Satoyo Okahira, Miwa Sasai, Kenji Funami +2 more
2007Molecular Immunology39 citations
Semantic Scholar
LRRC59 Regulates Trafficking of Nucleic Acid–Sensing TLRs from the Endoplasmic Reticulum via Association with UNC93B1
Megumi Tatematsu, Kenji Funami, N. Ishii, T. Seya +2 more
2015Journal of Immunology35 citations Open access
Semantic Scholar
Genetic Analysis of Hepatitis C Virus with Defective Genome and Its Infectivity in Vitro
K. Sugiyama, Kenji Suzuki, T. Nakazawa, Kenji Funami +10 more
2009Journal of Virology35 citations Open access
Semantic Scholar
Increased expression of Toll-like receptor 3 in intrahepatic biliary epithelial cells at sites of ductular reaction in diseased livers
Minoru Nakamura, Kenji Funami, A. Komori, Terufumi Yokoyama +13 more
2008Hepatology International32 citations Open access
Semantic Scholar
Lipoprotein component associated with hepatitis C virus is essential for virus infectivity.
Y. Shimizu, Takayuki Hishiki, S. Ujino, K. Sugiyama +2 more
2011Current Opinion in Virology28 citations
Semantic Scholar
The Anti-Oxidant Ergothioneine Augments the Immunomodulatory Function of TLR Agonists by Direct Action on Macrophages
Sumito Yoshida, H. Shime, Kenji Funami, Hiromi Takaki +3 more
2017PLoS ONE27 citations Open access
Semantic Scholar
Antibodies against human Toll-like receptors (TLRs): TLR distribution and localization in human dendritic cells
T. Seya, Kenji Funami, M. Taniguchi, M. Matsumoto
2005Journal of Endotoxin Research27 citations
Semantic Scholar
Mapping of the sites responsible for factor I-cofactor activity for cleavage of C3b and C4b on human C4b-binding protein (C4bp) by deletion mutagenesis.
Aya Fukui, Tomoko Yuasa-Nakagawa, Y. Murakami, Kenji Funami +5 more
2002Journal of Biochemistry (Tokyo)27 citations
Semantic Scholar
Assessment of the Toll-like receptor 3 pathway in endosomal signaling.
M. Matsumoto, Kenji Funami, Megumi Tatematsu, M. Azuma +1 more
2014Methods in Enzymology24 citations
Semantic Scholar
14-3-3-zeta participates in TLR3-mediated TICAM-1 signal-platform formation.
Kenji Funami, M. Matsumoto, C. Obuse, T. Seya
2016Molecular Immunology22 citations
Semantic Scholar
Type I Interferon-Independent Dendritic Cell Priming and Antitumor T Cell Activation Induced by a Mycoplasma fermentans Lipopeptide
Yohei Takeda, M. Azuma, Kenji Funami, H. Shime +2 more
2018Frontiers in Immunology16 citations Open access
Semantic Scholar
Interferon (IFN) and Cellular Immune Response Evoked in RNA-Pattern Sensing During Infection with Hepatitis C Virus (HCV)
M. Nakai, H. Oshiumi, Kenji Funami, Masaaki Okamoto +3 more
2015Italian National Conference on Sensors15 citations Open access
Semantic Scholar
Toll-IL-1-receptor-containing adaptor molecule-1: a signaling adaptor linking innate immunity to adaptive immunity.
M. Matsumoto, Kenji Funami, H. Oshiumi, T. Seya
2013Progress in Molecular Biology and Translational Science13 citations
Semantic Scholar
Multi-Step Regulation of Interferon Induction by Hepatitis C Virus
H. Oshiumi, Kenji Funami, Hussein H. Aly, M. Matsumoto +1 more
2013Archivum Immunologiae et Therapiae Experimentalis13 citations Open access
Semantic Scholar
Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells
J. Kasamatsu, Meng Deng, M. Azuma, Kenji Funami +5 more
2016BMC Immunology12 citations Open access
Semantic Scholar
Identification of a Regulatory Acidic Motif as the Determinant of Membrane Localization of TICAM-2
Kenji Funami, M. Matsumoto, Yoshiaki Enokizono, N. Ishii +4 more
2015Journal of Immunology8 citations
Semantic Scholar
Cytoplasmic dsRNA induces the expression of OCT3/4 and NANOG mRNAs in differentiated human cells
Guan-Ming Wang, T. Kouwaki, Kazuki Mugikura, Masaaki Okamoto +4 more
2019Journal of Biological Chemistry6 citations Open access
Semantic Scholar
The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc in ApcMin/+ mice
J. Ono, H. Shime, Hiromi Takaki, Ken Takashima +6 more
2017Journal of Biomedical Sciences5 citations Open access
Semantic Scholar
UNC 93 B 1 Physically Associates with Human TLR 8 and Regulates TLR 8-Mediated Signaling
Hiroki Itoh, Megumi Tatematsu, A. Watanabe, Katsunori Iwano +3 more
20182 citations
Semantic Scholar
The dataset of proteins specifically interacted with activated TICAM-1
Kenji Funami, M. Matsumoto, H. Oshiumi, C. Obuse +1 more
2016Data in Brief1 citations Open access
Semantic Scholar
ignaling in a Cell Type TLR 4 Internalization and TICAM-1 S Raftlin Controls Lipopolysaccharide-Induced
Megumi Tatematsu, Ryuji Yoshida, Yuka Morioka, N. Ishii +4 more
20160 citations
Semantic Scholar
Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells
J. Kasamatsu, M. Deng, M. Azuma, Kenji Funami +5 more
2016BMC Immunology0 citations Open access
Semantic Scholar

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