Researcher profile · Semantic Scholar

P. Akçakaya

h-index: 16
Works: 32
Citations: 1,773

Most-cited papers

Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq
B. Wienert, S. Wyman, C. Richardson, Charles D. Yeh +10 more
2018Science372 citations Open access
Semantic Scholar
In vivo CRISPR editing with no detectable genome-wide off-target mutations
P. Akçakaya, Maggie L. Bobbin, Jimmy A. Guo, José Malagón-López +18 more
2018Nature284 citations Open access
Semantic Scholar
The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma
D. Ozata, S. Caramuta, D. Velázquez-Fernández, P. Akçakaya +6 more
2011Endocrine-Related Cancer202 citations Open access
Semantic Scholar
miR-185 and miR-133b deregulation is associated with overall survival and metastasis in colorectal cancer.
P. Akçakaya, Susanne Ekelund, I. Kolosenko, S. Caramuta +5 more
2011International Journal of Oncology165 citations Open access
Semantic Scholar
Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing
Sandra Wimberger, N. Akrap, M. Firth, Johan Brengdahl +24 more
2022bioRxiv106 citations Open access
Semantic Scholar
Serum microRNA expression in pregnancies with preeclampsia.
Tuba Gunel, Y. G. Zeybek, P. Akçakaya, I. Kalelioğlu +3 more
2011Genetics and Molecular Research93 citations Open access
Semantic Scholar
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
A. Carreras, L. S. Pane, R. Nitsch, K. Madeyski-Bengtson +16 more
2019BMC Biology69 citations Open access
Semantic Scholar
Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma
S. Caramuta, Linkiat Lee, D. Ozata, P. Akçakaya +8 more
2013Blood Cancer Journal67 citations Open access
Semantic Scholar
Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma
S. Caramuta, Linkiat Lee, D. Ozata, P. Akçakaya +6 more
2013Endocrine-Related Cancer65 citations Open access
Semantic Scholar
Adenomatous polyposis coli-mediated control of β-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors
R. Miclea, M. Karperien, Cathy A. J. Bosch, G. van der Horst +9 more
2009BMC Developmental Biology63 citations Open access
Semantic Scholar
Functional role of the Ca²⁺-activated Cl⁻ channel DOG1/TMEM16A in gastrointestinal stromal tumor cells.
E. Berglund, P. Akçakaya, D. Berglund, F. Karlsson +8 more
2014Experimental Cell Research50 citations
Semantic Scholar
microRNA expression signatures of gastrointestinal stromal tumours: associations with imatinib resistance and patient outcome
P. Akçakaya, S. Caramuta, J. Åhlén, M. Ghaderi +5 more
2014British Journal of Cancer49 citations Open access
Semantic Scholar
miR‐125a‐5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors
Wen-Kuan Huang, P. Akçakaya, Anastasia Gangaev, Linkiat Lee +8 more
2018Experimental Cell Research36 citations Open access
Semantic Scholar
Negative DNA supercoiling induces genome-wide Cas9 off-target activity.
Matthew D. Newton, Marialucrezia Losito, Quentin M. Smith, Nishita Parnandi +9 more
2023Molecules and Cells31 citations Open access
Semantic Scholar
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes
Mihaela Zabulica, Raghuraman C. Srinivasan, P. Akçakaya, Gabriella Allegri +20 more
2021Molecular Therapy26 citations Open access
Semantic Scholar
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo
Burcu Bestas, Sandra Wimberger, Dmitrii Degtev, Alexandra Madsen +23 more
2023Nature Communications16 citations Open access
Semantic Scholar
Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells
E. Berglund, S. A. Ubhayasekera, F. Karlsson, P. Akçakaya +9 more
2014Anti-Cancer Drugs16 citations
Semantic Scholar
Evidence for Ca2+-Regulated ATP Release in Gastrointestinal Stromal Tumors
E. Berglund, D. Berglund, P. Akçakaya, M. Ghaderi +8 more
2013Experimental Cell Research14 citations Open access
Semantic Scholar
Imatinib Regulates miR-483-3p and Mitochondrial Respiratory Complexes in Gastrointestinal Stromal Tumors
Wen-Kuan Huang, Hao Shi, P. Akçakaya, K. Zeljić +6 more
2021International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
The functional SLC11A1 gene polymorphisms are associated with sarcoidosis in Turkish population
P. Akçakaya, Benura Azeroglu, Ipek Even, O. Ateş +3 more
2012Molecular Biology Reports10 citations
Semantic Scholar
In vivo CRISPR-Cas gene editing with no detectable genome-wide off-target mutations
P. Akçakaya, Maggie L. Bobbin, Jimmy A. Guo, J. M. López +18 more
2018bioRxiv9 citations Open access
Semantic Scholar
Negative DNA Supercoiling Induces Genome Wide Cas9 Off-Target Activity
Matthew D. Newton, Marialucrezia Losito, Quentin M. Smith, Nishita Parnandi +8 more
2022Social Science Research Network8 citations Open access
Semantic Scholar
Secretome protein signature of human gastrointestinal stromal tumor cells.
E. Berglund, E. Daré, R. Branca, P. Akçakaya +9 more
2015Experimental Cell Research7 citations
Semantic Scholar
MicroRNAs and Gastrointestinal Stromal Tumor.
P. Akçakaya, W. Lui
2015Advances in Experimental Medicine and Biology4 citations
Semantic Scholar
Molecular mechanisms of imatinib resistance in gastrointestinal stromal tumor with focus on microRNAs
P. Akçakaya
20141 citations
Semantic Scholar
Peer Review #1 of "DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness (v0.1)"
K. Jansen, F. Büscheck, K. Moeller, M. Kluth +342 more
20210 citations Open access
Semantic Scholar
Abstract 5317: Evidence for intracellular calcium-regulated secretion in gastrointestinal stromal tumor.
E. Berglund, D. Berglund, P. Akçakaya, M. Ghaderi +7 more
20130 citations
Semantic Scholar
Abstract 4940: Microrna expression profiling in adrenocortical neoplasia: Implications on tumor size and functionality
D. Velázquez-Fernández, S. Caramuta, D. Ozata, P. Akçakaya +6 more
20110 citations
Semantic Scholar
Immediate action of imatinib mesylate on calcium signaling in gastrointestinal stromal tumors (GIST).
Erik Berglund, Ming-You Lu, P. Akçakaya, J. Zedenius +5 more
2011Journal of Clinical Oncology0 citations
Semantic Scholar
The functional SLC11A1 gene polymorphisms are associated with sarcoidosis in Turkish population
P. Akçakaya, Benura Azeroglu, Ipek Even, O. Ateş +3 more
2011Molecular Biology Reports0 citations
Semantic Scholar
732 Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphomas
S. Caramuta, M. Berglund, D. Ozata, P. Akçakaya +5 more
20100 citations
Semantic Scholar
889 The involvement of miR-483 and its host gene IGF2 in development of adrenal cortical carcinoma
D. Ozata, S. Caramuta, P. Akçakaya, Hong Xie +3 more
20100 citations
Semantic Scholar

Marcello Maresca

×9

S. Caramuta×9

D. Ozata×7

E. Berglund×7

M. Firth×5

G. Sauter×5

M. Porritt×4

M. Bohlooly-y×4