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A. Ligon · SciRah

Researcher profile · Semantic Scholar

A. Ligon

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A. Ligon — researcher profile on SciRah

h-index: 66
Works: 187
Citations: 28K

Most-cited papers

Nivolumab in Patients With Relapsed or Refractory Hematologic Malignancy: Preliminary Results of a Phase Ib Study.
A. Lesokhin, S. Ansell, P. Armand, E. Scott +19 more
2016Journal of Clinical Oncology946 citations Open access
Semantic Scholar
Nivolumab for classical Hodgkin lymphoma after autologous stem-cell transplantation and brentuximab vedotin failure: a prospective phase 2 multi-cohort study
A. Younes, A. Santoro, M. Shipp, P. Zinzani +17 more
2016The Lancet Oncology764 citations Open access
Semantic Scholar
PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome.
M. Roemer, R. Advani, A. Ligon, Y. Natkunam +13 more
2016Journal of Clinical Oncology717 citations Open access
Semantic Scholar
Mechanisms and therapeutic implications of hypermutation in gliomas
M. Touat, Yvonne Y. Li, A. Boynton, L. Spurr +74 more
2020Nature553 citations Open access
Semantic Scholar
Targetable genetic features of primary testicular and primary central nervous system lymphomas.
B. Chapuy, M. Roemer, Chip Stewart, Yu-Xiang Tan +27 more
2014Blood517 citations Open access
Semantic Scholar
Validation of OncoPanel: A Targeted Next-Generation Sequencing Assay for the Detection of Somatic Variants in Cancer.
E. Garcia, A. Minkovsky, Yonghui Jia, Matthew D. Ducar +8 more
2017Archives of Pathology & Laboratory Medicine448 citations Open access
Semantic Scholar
Institutional implementation of clinical tumor profiling on an unselected cancer population.
L. Sholl, K. Do, Priyanka Shivdasani, E. Cerami +36 more
2016JCI Insight403 citations Open access
Semantic Scholar
Selumetinib in Children with BRAF-Aberrant or Neurofibromatosis type 1-Associated Recurrent, Refractory or Progressive Low-Grade Glioma: a Multi-Center Phase II Trial
J. Fangusaro, A. Onar-Thomas, T. Poussaint, Sheng-Jie Wu +30 more
2019The Lancet Oncology391 citations Open access
Semantic Scholar
Major Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma.
M. Roemer, R. Redd, F. Cader, Christine J. Pak +25 more
2018Journal of Clinical Oncology326 citations Open access
Semantic Scholar
Nivolumab for Relapsed/Refractory Diffuse Large B-Cell Lymphoma in Patients Ineligible for or Having Failed Autologous Transplantation: A Single-Arm, Phase II Study.
S. Ansell, M. Minnema, P. Johnson, J. Timmerman +14 more
2019Journal of Clinical Oncology318 citations Open access
Semantic Scholar
Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma.
Malak S. Abedalthagafi, W. Bi, A. Aizer, Parker Merrill +18 more
2016Neuro-Oncology275 citations Open access
Semantic Scholar
MYB-QKI rearrangements in Angiocentric Glioma drive tumorigenicity through a tripartite mechanism
P. Bandopadhayay, L. Ramkissoon, P. Jain, G. Bergthold +58 more
2016Nature Genetics243 citations Open access
Semantic Scholar
Pembrolizumab in Relapsed or Refractory Primary Mediastinal Large B-Cell Lymphoma
P. Armand, S. Rodig, V. Melnichenko, C. Thieblemont +25 more
2019Journal of Clinical Oncology232 citations Open access
Semantic Scholar
Nivolumab for Newly Diagnosed Advanced-Stage Classic Hodgkin Lymphoma: Safety and Efficacy in the Phase II CheckMate 205 Study.
R. Ramchandren, E. Domingo-Domènech, A. Rueda, M. Trněný +16 more
2019Journal of Clinical Oncology212 citations Open access
Semantic Scholar
A molecularly integrated grade for meningioma
Joseph Driver, Samantha E. Hoffman, S. Tavakol, Eleanor L. Woodward +24 more
2021Neuro-Oncology202 citations Open access
Semantic Scholar
A NOVEL SS18-SSX FUSION-SPECIFIC ANTIBODY FOR THE DIAGNOSIS OF SYNOVIAL SARCOMA
E. Baranov, M. McBride, A. Bellizzi, A. Ligon +3 more
2020American Journal of Surgical Pathology196 citations Open access
Semantic Scholar
Classical Hodgkin Lymphoma with Reduced β2M/MHC Class I Expression is Associated with Inferior Outcome Independent of 9p24.1 Status
M. Roemer, R. Advani, R. Redd, G. Pinkus +12 more
2016Cancer immunology research176 citations Open access
Semantic Scholar
Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas
G. Shankar, Malak S. Abedalthagafi, R. Vaubel, Parker Merrill +26 more
2016Neuro-Oncology152 citations Open access
Semantic Scholar
Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial.
Patrick Y. Wen, M. Touat, B. Alexander, I. Mellinghoff +40 more
2019Journal of Clinical Oncology144 citations Open access
Semantic Scholar
Atypical Spindle Cell Lipomatous Tumor: Clinicopathologic Characterization of 232 Cases Demonstrating a Morphologic Spectrum
A. Mariño-Enríquez, A. Nascimento, A. Ligon, Cher-Wei Liang +1 more
2017American Journal of Surgical Pathology140 citations
Semantic Scholar
A Phase 2 Trial of Selumetinib in Children with Recurrent Optic Pathway and Hypothalamic Low-Grade Glioma without NF1: A Pediatric Brain Tumor Consortium Study.
J. Fangusaro, A. Onar-Thomas, T. Poussaint, Sheng-Jie Wu +19 more
2021Neuro-Oncology136 citations Open access
Semantic Scholar
Genetic Basis for PD-L1 Expression in Squamous Cell Carcinomas of the Cervix and Vulva.
B. Howitt, Heather H. Sun, M. Roemer, Alyssa Kelley +18 more
2016JAMA Oncology130 citations Open access
Semantic Scholar
Molecular and clinicopathologic features of gliomas harboring NTRK fusions
Matthew Torre, V. Vasudevaraja, J. Serrano, M. DeLorenzo +15 more
2020Acta Neuropathologica Communications113 citations Open access
Semantic Scholar
Combination inhibition of PI3K and mTORC1 yields durable remissions in orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases
Jing Ni, S. Ramkissoon, Shao-Zhen Xie, S. Goel +21 more
2016Nature Medicine112 citations Open access
Semantic Scholar
Landscape of genomic alterations in pituitary adenomas
W. Bi, Peleg M. Horowitz, Noah F. Greenwald, Malak S. Abedalthagafi +16 more
2016Clinical Cancer Research106 citations Open access
Semantic Scholar
Preclinical efficacy of the MDM2 inhibitor RG7112 in MDM2 amplified and TP53 wild-type glioblastomas
M. Verreault, C. Schmitt, L. Goldwirt, K. Pelton +15 more
2015Clinical Cancer Research102 citations Open access
Semantic Scholar
ARID1A and TERT promoter mutations in dedifferentiated meningioma
Malak S. Abedalthagafi, W. Bi, Parker Merrill, W. Gibson +8 more
2015Cancer Genetics82 citations Open access
Semantic Scholar
A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma.
A. Aizer, Malak S. Abedalthagafi, W. Bi, M. Horvath +14 more
2015Neuro-Oncology77 citations Open access
Semantic Scholar
Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors
S. Ramkissoon, P. Bandopadhayay, Jaeho Hwang, L. Ramkissoon +33 more
2017Neuro-Oncology75 citations Open access
Semantic Scholar
Spatial Signatures Identify Immune Escape via PD-1 as a Defining Feature of T-cell/Histiocyte-rich Large B-cell Lymphoma.
G. Griffin, J. Weirather, M. Roemer, Mikel Lipschitz +27 more
2020Blood49 citations Open access
Semantic Scholar
Detection of ERBB2 Amplification by Next-Generation Sequencing Predicts HER2 Expression in Colorectal Carcinoma.
Odise Cenaj, A. Ligon, J. Hornick, L. Sholl
2019American Journal of Clinical Pathology49 citations Open access
Semantic Scholar
Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma.
S. Ramkissoon, W. Bi, S. Schumacher, Lori A. Ramkissoon +38 more
2015Neuro-Oncology47 citations Open access
Semantic Scholar
Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.
G. Bergthold, P. Bandopadhayay, Y. Hoshida, S. Ramkissoon +21 more
2015Neuro-Oncology45 citations Open access
Semantic Scholar
PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome
M. Roemer, R. Advani, A. Ligon, Y. Natkunam +11 more
201538 citations
Semantic Scholar
Contemporary prognostic signatures and refined risk stratification of gliomas: An analysis of 4400 tumors
H. Ghosh, R. Patel, E. Woodward, N. Greenwald +26 more
2024Neuro-Oncology33 citations Open access
Semantic Scholar
Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions
Harshabad Singh, Yvonne Y. Li, L. Spurr, A. Shinagare +26 more
2021Clinical Cancer Research29 citations Open access
Semantic Scholar
Detection of ERBB2 amplification in uterine serous carcinoma by next-generation sequencing: an approach highly concordant with standard assays
Carrie Robinson, B. Harrison, A. Ligon, Fei Dong +4 more
2020Modern Pathology28 citations Open access
Semantic Scholar
Leveraging molecular datasets for biomarker-based clinical trial design in glioblastoma
S. Tanguturi, L. Trippa, S. Ramkissoon, K. Pelton +9 more
2017Neuro-Oncology28 citations Open access
Semantic Scholar
Pembrolizumab in Patients with Relapsed or Refractory Primary Mediastinal Large B-Cell Lymphoma (PMBCL): Data from the Keynote-013 and Keynote-170 Studies
P. Armand, S. Rodig, V. Melnichenko, C. Thieblemont +25 more
2018Blood24 citations Open access
Semantic Scholar
A phase II prospective study of selumetinib in children with recurrent or refractory low-grade glioma (LGG): A Pediatric Brain Tumor Consortium (PBTC) study.
J. Fangusaro, A. Onar-Thomas, T. Young-Poussaint, Sheng-Jie Wu +16 more
201723 citations
Semantic Scholar
Genomic characterization of recurrent high-grade astroblastoma.
T. Bale, Malak S. Abedalthagafi, W. Bi, Yun J. Kang +8 more
2016Cancer Genetics23 citations
Semantic Scholar
Characterization of molecular signatures of supratentorial ependymomas
Matthew Torre, S. Alexandrescu, A. Dubuc, A. Ligon +2 more
2019Modern Pathology17 citations Open access
Semantic Scholar
A Phase 2 PBTC Study of Selumetinib for Recurrent/Progressive Pediatric Low-Grade Glioma: Strata 2, 5, and 6 with Long-term Outcomes on Strata 1, 3, and 4.
J. Fangusaro, A. Onar-Thomas, T. Young-Poussaint, Shelly Lensing +15 more
2025Neuro-Oncology16 citations Open access
Semantic Scholar
ALK amplification and rearrangements are recurrent targetable events in congenital and adult glioblastoma
A. Blandin, Ross M. Giglio, M. Graham, Guadalupe Garcia +42 more
2023Clinical Cancer Research15 citations Open access
Semantic Scholar
Integrated Genomic Characterization of a Pineal Parenchymal Tumor of Intermediate Differentiation.
Yun J. Kang, W. Bi, A. Dubuc, Louine Martineau +7 more
2016World Neurosurgery12 citations
Semantic Scholar
Chromosomal microarray analysis in pregnancy loss: Is it time for a consensus approach?
S. Schilit, C. Studwell, Pamela Flatley, M. Listewnik +3 more
2022Prenatal Diagnosis11 citations
Semantic Scholar
Case Report: Next generation sequencing identifies a NAB2-STAT6 fusion in Glioblastoma
P. Diamandis, R. Ferrer-Luna, Raymond Y. Huang, R. Folkerth +5 more
2016Diagnostic Pathology11 citations Open access
Semantic Scholar
LGG-08. A PHASE II PROSPECTIVE STUDY OF SELUMETINIB IN CHILDREN WITH RECURRENT OR REFRACTORY LOW-GRADE GLIOMA (LGG): A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY
J. Fangusaro, A. Onar-Thomas, T. Poussaint, Sheng-Jie Wu +30 more
20178 citations Open access
Semantic Scholar
LTBK-01. UPDATES ON THE PHASE II AND RE-TREATMENT STUDY OF AZD6244 (SELUMETINIB) FOR CHILDREN WITH RECURRENT OR REFRACTORY PEDIATRIC LOW GRADE GLIOMA: A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY
J. Fangusaro, A. Onar-Thomas, T. Poussaint, Sheng-Jie Wu +15 more
2018Neuro-Oncology7 citations Open access
Semantic Scholar
Chromosome 9p24.1/PD-L1/PD-L2Alterations and PD-L1 Expression and Treatment Outcomes in Patients with Classical Hodgkin Lymphoma Treated with Nivolumab (PD-1 Blockade)
M. Roemer, A. Ligon, A. Engert, A. Younes +19 more
20167 citations
Semantic Scholar

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R. Beroukhim×16
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R. Beroukhim — researcher profile on SciRah
S. Ramkissoon×15
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S. Ramkissoon — researcher profile on SciRah
K. Ligon×15
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K. Ligon — researcher profile on SciRah
M. Shipp×14
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M. Shipp — researcher profile on SciRah

×13

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S. Rodig — researcher profile on SciRah

S. Santagata×11

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S. Santagata — researcher profile on SciRah

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P. Armand — researcher profile on SciRah

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M. Roemer — researcher profile on SciRah

N. Lindeman×10

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N. Lindeman — researcher profile on SciRah

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W. Bi — researcher profile on SciRah

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I. Dunn — researcher profile on SciRah

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D. Neuberg — researcher profile on SciRah