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J. Fangusaro · SciRah

Researcher profile · Semantic Scholar

J. Fangusaro

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J. Fangusaro — researcher profile on SciRah

h-index: 43
Works: 194
Citations: 6,598

Most-cited papers

Selumetinib in Children with BRAF-Aberrant or Neurofibromatosis type 1-Associated Recurrent, Refractory or Progressive Low-Grade Glioma: a Multi-Center Phase II Trial
J. Fangusaro, A. Onar-Thomas, T. Poussaint, Sheng-Jie Wu +30 more
2019The Lancet Oncology391 citations Open access
Semantic Scholar
Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.
J. Fangusaro, O. Witt, Pablo Hernáiz Driever, A. Bag +21 more
2020The Lancet Oncology153 citations
Semantic Scholar
Pediatric low-grade gliomas: next biologically driven steps
David T. W. Jones, M. Kieran, E. Bouffet, S. Alexandrescu +25 more
2018Neuro-Oncology146 citations Open access
Semantic Scholar
A Phase 2 Trial of Selumetinib in Children with Recurrent Optic Pathway and Hypothalamic Low-Grade Glioma without NF1: A Pediatric Brain Tumor Consortium Study.
J. Fangusaro, A. Onar-Thomas, T. Poussaint, Sheng-Jie Wu +19 more
2021Neuro-Oncology136 citations Open access
Semantic Scholar
Management of Pediatric Low-Grade Glioma
P. de Blank, P. Bandopadhayay, D. Haas-Kogan, M. Fouladi +1 more
2019Current opinion in pediatrics114 citations Open access
Semantic Scholar
Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma
Nalin Gupta, L. Goumnerova, P. Manley, Susan N. Chi +60 more
2018Neuro-Oncology101 citations Open access
Semantic Scholar
Pineoblastoma segregates into molecular sub-groups with distinct clinicopathologic features: A Rare Brain Tumor Consortium registry study
Bryan Li, A. Vasiljevic, C. Dufour, F. Yao +40 more
2019Acta Neuropathologica92 citations Open access
Semantic Scholar
MEK Inhibitors for Neurofibromatosis Type 1 Manifestations: Clinical Evidence and Consensus.
P. de Blank, A. Gross, S. Akshintala, J. Blakeley +28 more
2022Neuro-Oncology88 citations Open access
Semantic Scholar
Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival
Amanda E Marinoff, Clement Ma, D. Guo, M. Snuderl +13 more
2017Journal of Neuro-Oncology84 citations Open access
Semantic Scholar
Phase II Trial of Response-Based Radiation Therapy for Patients With Localized CNS Nongerminomatous Germ Cell Tumors: A Children's Oncology Group Study.
J. Fangusaro, Sheng-Jie Wu, S. MacDonald, E. Murphy +11 more
2019Journal of Clinical Oncology83 citations Open access
Semantic Scholar
The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science
Jena V. Lilly, J. L. Rokita, Jennifer L. Mason, Tatiana S. Patton +96 more
2022bioRxiv78 citations Open access
Semantic Scholar
A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.
P. Sin‐Chan, Iqra Mumal, Tannu Suwal, Ben Ho +50 more
2019Cancer Cell74 citations Open access
Semantic Scholar
Improved neuropsychological outcomes following proton therapy relative to x-ray therapy for pediatric brain tumor patients.
J. Gross, S. Powell, F. Zelko, W. Hartsell +6 more
2019Neuro-Oncology74 citations Open access
Semantic Scholar
Pediatric low-grade glioma: State-of-the-art and ongoing challenges.
J. Fangusaro, D. Jones, R. Packer, David H. Gutmann +8 more
2023Neuro-Oncology69 citations Open access
Semantic Scholar
A Phase I Trial of Panobinostat in Children with Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium (PBTC-047).
Michelle Monje, Tabitha Cooney, J. Glod, Jie Huang +15 more
2023Neuro-Oncology57 citations
Semantic Scholar
Implications of new understandings of gliomas in children and adults with NF1: report of a consensus conference
R. Packer, A. Iavarone, David T. W. Jones, J. Blakeley +15 more
2020Neuro-Oncology56 citations Open access
Semantic Scholar
Clinical Pharmacokinetics and Pharmacodynamics of Selumetinib
O. Campagne, K. Yeo, J. Fangusaro, C. Stewart
2020Clinical Pharmacokinetics53 citations Open access
Semantic Scholar
Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial
Theodore S. Johnson, T. MacDonald, R. Pacholczyk, D. Aguilera +34 more
2023Neuro-Oncology46 citations Open access
Semantic Scholar
Clinical Activity of Mitogen-Activated Protein Kinase–Targeted Therapies in Patients With Non–V600 BRAF-Mutant Tumors
M. Dankner, Yi-Fan Wang, R. Fazelzad, Benny Johnson +25 more
2022JCO Precision Oncology44 citations Open access
Semantic Scholar
Central nervous system tumors in adolescents and young adults: A Society for Neuro-Oncology consensus review on diagnosis, management, and future directions.
M. Lim-Fat, J. Bennett, Q. Ostrom, M. Touat +36 more
2024Neuro-Oncology26 citations Open access
Semantic Scholar
The transcriptional repressor REST drives lineage-stage-specific chromatin compaction at Ptch1 and AKT hyperactivation in medulloblastoma
Tara H. W. Dobson, R. Tao, Jyothishmathi Swaminathan, S. Maegawa +19 more
2019Science Signaling25 citations Open access
Semantic Scholar
Resistance, rebound, and recurrence regrowth patterns in pediatric low-grade glioma treated by MAPK inhibition: A modified Delphi approach to build international consensus-based definitions—International Pediatric Low-Grade Glioma Coalition
Patricia O’Hare, Tabitha Cooney, P. de Blank, David H. Gutmann +29 more
2024Neuro-Oncology22 citations Open access
Semantic Scholar
Towards Consistency in Pediatric Brain Tumor Measurements: Challenges, Solutions, and the Role of AI-Based Segmentation.
A. Familiar, Anahita Fathi Kazerooni, A. Vossough, J. Ware +17 more
2024Neuro-Oncology21 citations Open access
Semantic Scholar
Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium
S. Vajapeyam, Douglas L. Brown, C. Billups, Z. Patay +8 more
2020American Journal of Neuroradiology20 citations Open access
Semantic Scholar
Pineoblastoma in Children Less Than Six Years of Age: The Head Start I, II and III Experience
M. Abdelbaki, M. Abu-Arja, T. Davidson, J. Fangusaro +5 more
2020Pediatric Blood & Cancer17 citations Open access
Semantic Scholar
Advances in the classification and treatment of pediatric brain tumors
J. Fangusaro, P. Bandopadhayay
2020Current opinion in pediatrics17 citations
Semantic Scholar
Population Pharmacokinetics of Selumetinib and Its Metabolite N‐desmethyl‐selumetinib in Adult Patients With Advanced Solid Tumors and Children With Low‐Grade Gliomas
Y. Patel, V. Daryani, P. Patel, Diansong Zhou +5 more
2017CPT: Pharmacometrics & Systems Pharmacology17 citations Open access
Semantic Scholar
Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical Care
R. Summers, S. Castellino, C. C. Porter, T. MacDonald +13 more
2022JCO Precision Oncology15 citations
Semantic Scholar
LGG-04. A PHASE II RE-TREATMENT STUDY OF SELUMETINIB FOR RECURRENT OR PROGRESSIVE PEDIATRIC LOW-GRADE GLIOMA (pLGG): A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY
J. Fangusaro, A. Onar-Thomas, Sheng-Jie Wu, T. Poussaint +9 more
2020Neuro-Oncology15 citations Open access
Semantic Scholar
Nervous system (NS) Tumors in Cancer Predisposition Syndromes
Prabhumallikarjun Patil, B. Pencheva, Vinayak Mahesh Patil, J. Fangusaro
2022Neurotherapeutics14 citations Open access
Semantic Scholar
A Phase 2 Trial of Response-Based Radiation Therapy for Localized Central Nervous System Germ Cell Tumors: Patterns of Failure and Radiation Dosimetry for Nongerminomatous Germ Cell Tumors
E. Murphy, G. Dhall, J. Fangusaro, U. Bartels +13 more
2022International Journal of Radiation Oncology, Biology, Physics13 citations Open access
Semantic Scholar
REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature
S. Shaik, Bridget A. Kennis, S. Maegawa, Keri L. Schadler +8 more
2017OncoTarget13 citations Open access
Semantic Scholar
Paediatric Strategy Forum for medicinal product development in mitogen-activated protein kinase pathway inhibitors: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
A. Pearson, Carl E. Allen, J. Fangusaro, C. Hutter +34 more
2022European Journal of Cancer12 citations Open access
Semantic Scholar
DIPG-22. A PHASE 1 TRIAL OF THE HISTONE DEACETYLASE INHIBITOR PANOBINOSTAT IN PEDIATRIC PATIENTS WITH RECURRENT OR REFRACTORY DIFFUSE INTRINSIC PONTINE GLIOMA: A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY
Tabitha Cooney, A. Onar-Thomas, Jie Huang, R. Lulla +7 more
2018Neuro-Oncology12 citations Open access
Semantic Scholar
Children’s Oncology Group’s 2023 Blueprint for Research: Central Nervous System Tumors
S. Leary, A. Onar-Thomas, J. Fangusaro, N. Gottardo +5 more
2023Pediatric Blood & Cancer11 citations Open access
Semantic Scholar
Optimizing preclinical pediatric low-grade glioma models for meaningful clinical translation.
T. Milde, J. Fangusaro, Michael J. Fisher, C. Hawkins +5 more
2023Neuro-Oncology11 citations Open access
Semantic Scholar
Phase 1 Study of Pomalidomide in Children with Recurrent, Refractory and Progressive Central Nervous System Tumors: A Pediatric Brain Tumor Consortium Trial
J. Fangusaro, D. Mitchell, M. Koçak, G. Robinson +7 more
2020Pediatric Blood & Cancer11 citations Open access
Semantic Scholar
Imaging response assessment for CNS germ cell tumours: consensus recommendations from the European Society for Paediatric Oncology Brain Tumour Group and North American Children's Oncology Group.
G. Morana, D. Shaw, S. MacDonald, C. Alapetite +19 more
2022The Lancet Oncology9 citations Open access
Semantic Scholar
Phase II Trial of Response-Based Radiation Therapy for Patients with Localized Germinoma: A Children's Oncology Group Study.
U. Bartels, A. Onar-Thomas, Sunita K. Patel, D. Shaw +14 more
2021Neuro-Oncology8 citations Open access
Semantic Scholar
Phase 2 Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors
J. Fangusaro, M. Cefalo, M. Garrè, L. Marshall +12 more
2021Frontiers in Oncology8 citations Open access
Semantic Scholar
CNSC-02. PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC)-056: A PHASE 1 STUDY OF THE ADAM-10 INHIBITOR, INCB007839, IN CHILDREN WITH RECURRENT/PROGRESSIVE HIGH-GRADE GLIOMAS TO TARGET MICROENVIRONMENTAL NEUROLOGIN-3
Alicia C. Lenzen, S. Partap, C. Billups, T. Poussaint +10 more
2024Neuro-Oncology7 citations Open access
Semantic Scholar
Evaluating Focal Areas of Signal Intensity (FASI) in Children with Neurofibromatosis Type-1 (NF1) Treated with Selumetinib on Pediatric Brain Tumor Consortium (PBTC)-029B
Natasha Pillay-Smiley, J. Leach, A. Lane, T. Hummel +2 more
2023Cancers7 citations Open access
Semantic Scholar
Neonatal Central Nervous System Tumors.
Shubin W Shahab, J. Fangusaro
2021Clinics of Perinatology7 citations
Semantic Scholar
A phase II clinical study of pomalidomide (CC-4047) monotherapy for children and young adults with recurrent or progressive primary brain tumors.
J. Fangusaro, F. Locatelli, M. Garrè, L. Marshall +12 more
2019Journal of Clinical Oncology7 citations
Semantic Scholar
LTBK-01. UPDATES ON THE PHASE II AND RE-TREATMENT STUDY OF AZD6244 (SELUMETINIB) FOR CHILDREN WITH RECURRENT OR REFRACTORY PEDIATRIC LOW GRADE GLIOMA: A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY
J. Fangusaro, A. Onar-Thomas, T. Poussaint, Sheng-Jie Wu +15 more
2018Neuro-Oncology7 citations Open access
Semantic Scholar
GERM-15. A PHASE 2 TRIAL OF RESPONSE-BASED RADIATION THERAPY FOR PATIENTS WITH LOCALIZED CENTRAL NERVOUS SYSTEM GERM CELL TUMORS (CNS GCT): A CHILDREN’S ONCOLOGY GROUP (COG) STUDY
J. Fangusaro, Sheng-Jie Wu, S. MacDonald, E. Murphy +13 more
20186 citations Open access
Semantic Scholar
Primary Diffuse Leptomeningeal Melanomatosis in a Child with Extracranial Metastasis: Case Report
Shubin W Shahab, Prabhumallikarjun Patil, J. Fangusaro, Brooke Patteson +5 more
2024Current Oncology5 citations Open access
Semantic Scholar
Consensus framework for conducting phase I/II clinical trials for children, adolescents, and young adults with pediatric low-grade glioma: Guidelines established by the International Pediatric Low-Grade Glioma Coalition Clinical Trial Working Group.
Sabine Mueller, J. Fangusaro, A. O. Thomas, Thomas S. Jacques +14 more
2023Neuro-Oncology5 citations Open access
Semantic Scholar
DIPG-10. A Phase I trial of panobinostat following radiation therapy in children with diffuse intrinsic pontine glioma (DIPG) or H3K27M-mutated thalamic diffuse midline glioma (DMG): Report from the Pediatric Brain Tumor Consortium (PBTC-047)
Michelle Monje, Tabitha Cooney, J. Glod, Jie Huang +11 more
2022Neuro-Oncology5 citations Open access
Semantic Scholar
Multicenter Analysis of Genomically Targeted Single Patient Use Requests for Pediatric Neoplasms
Himalee S. Sabnis, D. Shulman, B. Mizukawa, N. Bouvier +12 more
2021Journal of Clinical Oncology5 citations Open access
Semantic Scholar

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