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A. Myers · SciRah

Researcher profile · Semantic Scholar

A. Myers

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A. Myers — researcher profile on SciRah

h-index: 19
Works: 41
Citations: 1,857

Most-cited papers

High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability
L. Cheung, B. Hennessy, Jie Li, Shuang-Xing Yu +13 more
2011Cancer Discovery484 citations Open access
Semantic Scholar
Oncogenic mutations in cervical cancer: genomic differences between adenocarcinomas and squamous cell carcinomas of the cervix
Alexi A. Wright, B. Howitt, A. Myers, S. Dahlberg +12 more
2013Cancer259 citations Open access
Semantic Scholar
Essential and opposing roles of zebrafish β-catenins in the formation of dorsal axial structures and neurectoderm
G. Bellipanni, Máté Varga, S. Maegawa, Y. Imai +5 more
2006Development152 citations
Semantic Scholar
What a Tangled Web We Weave: Emerging Resistance Mechanisms to Inhibition of the Phosphoinositide 3-kinase Pathway
S. Klempner, A. Myers, L. Cantley
2013Cancer Discovery150 citations Open access
Semantic Scholar
A first-in-human phase 1/2 study of FGF401 and combination of FGF401 with spartalizumab in patients with hepatocellular carcinoma or biomarker-selected solid tumors
S. Chan, M. Schuler, Yoon-Koo Kang, C. Yen +32 more
2022Journal of experimental & clinical cancer research : CR75 citations Open access
Semantic Scholar
Canakinumab as Adjuvant Therapy in Patients With Completely Resected Non–Small-Cell Lung Cancer: Results From the CANOPY-A Double-Blind, Randomized Clinical Trial
E. Garon, Shun Lu, Y. Goto, P. D. de Marchi +15 more
2023Journal of Clinical Oncology73 citations
Semantic Scholar
Characterization of Mouse Rsk4 as an Inhibitor of Fibroblast Growth Factor-RAS-Extracellular Signal-Regulated Kinase Signaling
A. Myers, L. Corson, J. Rossant, J. Baker
2004Molecular and Cellular Biology64 citations Open access
Semantic Scholar
New Strategies in Endometrial Cancer: Targeting the PI3K/mTOR Pathway—The Devil Is in the Details
A. Myers
2013Clinical Cancer Research60 citations Open access
Semantic Scholar
A Phase I Study of IDH305 in Patients with Advanced Malignancies Including Relapsed/Refractory AML and MDS That Harbor IDH1R132 Mutations
C. Dinardo, A. Schimmer, K. Yee, A. Hochhaus +17 more
201657 citations Open access
Semantic Scholar
A genetic mouse model of invasive endometrial cancer driven by concurrent loss of Pten and Lkb1 is highly responsive to mTOR inhibition
Hai-Ling Cheng, Pi-Xu Liu, Fan Zhang, Erbo Xu +10 more
2013Cancer Research56 citations Open access
Semantic Scholar
PTEN loss is a context-dependent outcome determinant in obese and non-obese endometrioid endometrial cancer patients
S. Westin, Z. Ju, R. Broaddus, C. Krakstad +11 more
2015Molecular Oncology50 citations Open access
Semantic Scholar
β-Catenin mutations in recurrent FIGO IA grade I endometrioid endometrial cancers.
A. Myers, W. Barry, M. Hirsch, U. Matulonis +1 more
2014Gynecologic Oncology49 citations
Semantic Scholar
Phase II, 2-Stage, 2-Arm, PIK3CA Mutation Stratified Trial of MK-2206 in Recurrent Endometrial Cancer
A. Myers, P. Konstantinopoulos, W. Barry, W. Luo +14 more
2019International Journal of Cancer43 citations Open access
Semantic Scholar
Phase I dose‐escalation study of capmatinib (INC280) in Japanese patients with advanced solid tumors
T. Esaki, F. Hirai, A. Makiyama, T. Seto +8 more
2019Cancer Science38 citations Open access
Semantic Scholar
Targeting a Common Collaborator in Cancer Development
A. Myers, L. Cantley
2010Science Translational Medicine35 citations Open access
Semantic Scholar
Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study
A. Myers, V. Filiaci, Yuping Zhang, M. Pearl +10 more
2015Gynecologic Oncology28 citations Open access
Semantic Scholar
Phase II, two-stage, two-arm, PIK3CA mutation stratified trial of MK-2206 in recurrent endometrial cancer (EC).
A. Myers, R. Broaddus, V. Makker, P. Konstantinopoulos +13 more
201324 citations
Semantic Scholar
Abstract C45: Phase I study of WNT974, a first-in-class Porcupine inhibitor, in advanced solid tumors
F. Janku, R. Connolly, P. LoRusso, M. D. de Jonge +9 more
201523 citations
Semantic Scholar
A phase 1b study of the MET inhibitor capmatinib combined with cetuximab in patients with MET-positive colorectal cancer who had progressed following anti-EGFR monoclonal antibody treatment
J. Delord, G. Argilés, J. Fayette, L. Wirth +13 more
2020Investigational new drugs21 citations
Semantic Scholar
Abstract CT106: Ph I/II study of FGF401 in adult pts with HCC or solid tumors characterized by FGFR4/KLB expression
S. Chan, Jui-Yen Chia, M. Schuler, Chia-Chi Lin +12 more
201719 citations
Semantic Scholar
Clinical Investigation of Receptor and Non-Receptor Tyrosine Kinase Inhibitors for the Treatment of Epithelial Ovarian Cancer
S. Klempner, A. Myers, G. Mills, S. Westin
2013Expert Opinion on Pharmacotherapy19 citations Open access
Semantic Scholar
A phase II study of MK-2206, an AKT inhibitor, in uterine serous carcinoma
E. Stover, N. Xiong, A. Myers, N. Tayob +15 more
2022Gynecologic Oncology Reports16 citations Open access
Semantic Scholar
Contribution of machine learning to tumor growth inhibition modeling for hepatocellular carcinoma patients under Roblitinib (FGF401) drug treatment
M. Wilbaux, D. Demanse, Yi Gu, A. Jullion +3 more
2022CPT: Pharmacometrics & Systems Pharmacology10 citations Open access
Semantic Scholar
Model‐based dose selection to inform translational clinical oncology development of WNT974, a first‐in‐class Porcupine inhibitor
Yan Ji, Pai‐Hsi Huang, Steve Woolfenden, A. Myers
2022Clinical and Translational Science9 citations Open access
Semantic Scholar
Integration of Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy into Model‐Informed Dose Selection in Oncology First‐in‐Human Study: A Case of Roblitinib (FGF401)
M. Wilbaux, Shu Yang, A. Jullion, D. Demanse +4 more
2022Clinical pharmacology and therapy8 citations
Semantic Scholar
Phase II, single stage, cohort expansion study of MK-2206 in recurrent endometrial serous cancer.
P. Konstantinopoulos, V. Makker, W. Barry, Joyce F. Liu +12 more
20147 citations
Semantic Scholar
Repurposing the Pap Smear: One Step Closer to Gynecologic Cancer Screening
S. Westin, G. Mills, A. Myers
2013Science Translational Medicine7 citations Open access
Semantic Scholar
Sugar free, cancer free?
A. Myers, L. Cantley
2012Nutrition (Burbank, Los Angeles County, Calif.)7 citations Open access
Semantic Scholar
Biomarker-integrated study of single agent targeting molecular alterations of PI3KCA, MET, ALK, ROS1, KRAS, NRAS or BRAF in advanced NSCLC: Phase 2 umbrella trial in China (CTONG1505).
Qing Zhou, Xu-Chao Zhang, H. Tu, Bin Gan +13 more
2018Annals of Oncology5 citations Open access
Semantic Scholar
JCSE01.09 Cluster Trial: Ph2 Biomarker-Integrated Study of Single Agent Alpelisib, Capmatinib, Ceritinib and Binimetinib in advNSCLC
Y. Wu, Q. Zhou, X. Zhang, H. Tu +14 more
2018Journal of Thoracic Oncology4 citations Open access
Semantic Scholar
A first-in-human phase 1/2 study of FGF401 and combination of FGF401 with spartalizumab in patients with hepatocellular carcinoma or biomarker-selected solid tumors
S. Chan, M. Schuler, Yoon-Koo Kang, C. Yen +32 more
2022Journal of experimental & clinical cancer research : CR2 citations Open access
Semantic Scholar
PTEN loss as a context-dependent determinant of patient outcomes in obese and non-obese endometrioid endometrial cancer patients.
Z. Ju, S. Westin, R. Broaddus, Jie Li +7 more
20132 citations
Semantic Scholar
ACTR-74. A PHASE IB/II, OPEN-LABEL, MULTICENTER STUDY OF CAPMATINIB (INC280) ALONE AND IN COMBINATION WITH BUPARLISIB (BKM120) IN ADULT PATIENTS WITH RECURRENT GLIOBLASTOMA
M. J. van den Bent, A. Azaro, F. D. de Vos, J. Sepúlveda +12 more
20171 citations Open access
Semantic Scholar
Abstract 2140: Dual Wnt and EGFR-MAPK dependency ofBRAFV600E-mutant colorectal cancer
Youzhen Wang, Michael R. Palmer, S. Jaeger, Linda Bagdasarian +11 more
20151 citations
Semantic Scholar
Mutation and functional analysis of PIK3CA and PIK3R1 in endometrial cancer
L. Cheung, B. Hennessy, Jie Li, Shuang-Xing Yu +12 more
20111 citations
Semantic Scholar
Getting Knit-PI3Ky: PIK3CA Mutation Status to Direct Multimodality Therapy?
A. Myers, J. Meyerhardt, L. Cantley
2009Clinical Cancer Research1 citations Open access
Semantic Scholar
Translational PBPK modeling and model-informed drug development of IDH305, a complex CYP3A4 modulator.
Yan Ji, Wen Lin, Tycho Heimbach, A. Myers
2026Journal of Pharmacy and Science0 citations
Semantic Scholar
Phase I/II study of FGF401 in adult patients (pts) with hepatocellular carcinoma (HCC) or solid tumors and positive FGFR4/KLB expression
M. Schuler, S. Chan, C. Yen, Chia-Chi Lin +12 more
20170 citations
Semantic Scholar
Procédés de traitement de cancers colorectaux avec mutations en amont de la voie wnt
Linda Bagdasarian, Feng Cong, S. Jaeger, Margaret Elise Claughlin +7 more
20150 citations
Semantic Scholar
The Phosphatidylinositol 3‐Kinase Pathway in Human Malignancies
S. Klempner, Thanh-Trang T. Vo, A. Myers, L. Cantley
20150 citations
Semantic Scholar
Abstract 4265: Derivation and characterization of endometrial cancer cells resistant to phosphatidylinositol-3-kinase (PI3K) pathway inhibitors.
S. Klempner, A. Myers, Jane Li, G. Mills +1 more
20130 citations
Semantic Scholar

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