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L. Salmena · SciRah

Researcher profile · Semantic Scholar

L. Salmena

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L. Salmena — researcher profile on SciRah

h-index: 39
Works: 153
Citations: 22K

Most-cited papers

Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium
J. Chow, L. Salmena
2020Genes106 citations Open access
Semantic Scholar
microRNAs and Acute Myeloid Leukemia Chemoresistance: A Mechanistic Overview
M. Gabra, L. Salmena
2017Frontiers in Oncology73 citations Open access
Semantic Scholar
Mapping the cellular origin and early evolution of leukemia in Down syndrome
Elvin Wagenblast, Joana Araújo, O. Gan, Sarah K. Cutting +25 more
2021Science68 citations Open access
Semantic Scholar
Mitochondrion-targeted RNA therapies as a potential treatment strategy for mitochondrial diseases
Timofei Chernega, Jaehyoung Choi, L. Salmena, A. Andreazza
2022Molecular Therapy: Nucleic Acids33 citations Open access
Semantic Scholar
Plasma osteoprotegerin and breast cancer risk in BRCA1 and BRCA2 mutation carriers
L. Odén, M. Akbari, Tasnim Zaman, C. Singer +4 more
2016OncoTarget33 citations Open access
Semantic Scholar
Recent advances in PTEN signalling axes in cancer
J. Chow, L. Salmena
2020Faculty Reviews25 citations Open access
Semantic Scholar
Stroma-derived miR-214 coordinates tumor dissemination
F. Orso, Federico Virga, D. Dettori, Alberto Dalmasso +15 more
2023Journal of experimental & clinical cancer research : CR21 citations Open access
Semantic Scholar
PTENP1 is a ceRNA for PTEN: it’s CRISPR clear
M. Vitiello, Monica Evangelista, Yang Zhang, L. Salmena +2 more
2020Journal of Hematology & Oncology21 citations Open access
Semantic Scholar
Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition
G. Saffi, Evan Tang, Sami Mamand, Subothan Inpanathan +3 more
2021PLoS ONE20 citations Open access
Semantic Scholar
PTEN: History of a Tumor Suppressor.
L. Salmena
2016Methods in molecular biology18 citations
Semantic Scholar
The Complex Landscape of PTEN mRNA Regulation.
E. Sellars, M. Gabra, L. Salmena
2019Cold Spring Harbor Perspectives in Medicine16 citations Open access
Semantic Scholar
Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity
G. Saffi, Cheng-An Wang, E. Mangialardi, J. Vacher +2 more
2022Journal of Biological Chemistry15 citations Open access
Semantic Scholar
Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML
Gabriela Krivdova, V. Voisin, E. Schoof, Sajid A. Marhon +21 more
2022Cell Reports15 citations Open access
Semantic Scholar
SubID, a non-median dichotomization tool for heterogeneous populations, reveals the pan-cancer significance of INPP4B and its regulation by EVI1 in AML
I. Dzneladze, J. Woolley, Carla Rossell, Youqi Han +5 more
2018PLoS ONE15 citations Open access
Semantic Scholar
Discovery of miRNA–mRNA regulatory networks in glioblastoma reveals novel insights into tumor microenvironment remodeling
I. Grigore, A. Rajagopal, J. T. Chow, T. Stone +1 more
2024Scientific Reports14 citations Open access
Semantic Scholar
Uninterrupted Sedentary Behavior Downregulates BRCA1 Gene Expression
Rachael Pettapiece-Phillips, M. Kotlyar, Rania Chehade, L. Salmena +4 more
2015Cancer Prevention Research14 citations
Semantic Scholar
INPP4B promotes PDAC aggressiveness via PIKfyve and TRPML-1–mediated lysosomal exocytosis
G. Saffi, Lydia To, Nicholas Kleine, Me-Lo M. P. Che +8 more
2024Journal of Cell Biology13 citations Open access
Semantic Scholar
Reduced BRCA1 transcript levels in freshly isolated blood leukocytes from BRCA1 mutation carriers is mutation specific
Rania Chehade, Rachael Pettapiece-Phillips, L. Salmena, M. Kotlyar +4 more
2016Breast Cancer Research12 citations Open access
Semantic Scholar
Pseudogenes: Four Decades of Discovery.
L. Salmena
2021Methods in molecular biology11 citations
Semantic Scholar
Serum osteoprotegerin levels and mammographic density among high-risk women
O. Moran, Tasnim Zaman, A. Eisen, R. Demsky +9 more
2018Cancer Causes and Control8 citations
Semantic Scholar
A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
E. Sellars, Margarita Savguira, Jie Wu, Sabrina Cancelliere +8 more
2024iScience6 citations Open access
Semantic Scholar
Increased Serum Mir-150-3p Expression Is Associated with Radiological Lung Injury Improvement in Patients with COVID-19
Larissa C M Bueno, L. Paim, E. O. Minin, Luis M. da Silva +12 more
2022Viruses6 citations Open access
Semantic Scholar
INPP4B promotes leukemia by restricting leukemic stem cell differentiation through regulation of lysosomal functions
J. Woolley, Ke-Yue Chen, G. Genç, Daniel K. C. Lee +18 more
20216 citations Open access
Semantic Scholar
Plasma RANKL levels are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers
Tasnim Zaman, P. Sun, S. Narod, L. Salmena +1 more
2019OncoTarget6 citations Open access
Semantic Scholar
Essential gene networks in acute myeloid leukemia identified using a microRNA-knockout CRISPR library screen
M. Gabra, C. Pastrello, Nicole Machado, J. Chow +4 more
2019bioRxiv5 citations Open access
Semantic Scholar
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li +6 more
2025Molecular Oncology4 citations Open access
Semantic Scholar
A microRNA CRISPR screen reveals microRNA-483-3p as an apoptotic regulator in prostate cancer cells
J. T. Chow, Ayeisha Desjardins, Daniel K. C. Lee, I. Grigore +6 more
2025Cell Death and Disease4 citations Open access
Semantic Scholar
Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts
E. Mangialardi, Ke-Yue Chen, Brittany Salmon, J. Vacher +1 more
2019OncoTarget4 citations Open access
Semantic Scholar
The lipid phosphatase INPP4B controls pancreatic cancer cell migration and invasion by regulating fibronectin exocytosis
G. Saffi, Nicholas Kleine, L. Salmena
2025Journal of Biological Chemistry2 citations Open access
Semantic Scholar
Phosphoinositide-focused CRISPR screen identifies novel genetic vulnerabilities in PDAC and AML cells
Daniel K. C. Lee, Ryan Loke, Jonathan T S Chow, M. Gabra +1 more
2024bioRxiv2 citations
Semantic Scholar
Mapping the Cellular Origin and Early Evolution of Leukemia in Down Syndrome
Elvin Wagenblast, Joana Araújo, Olga I. Gan, Sarah K. Cutting +19 more
2020bioRxiv2 citations Open access
Semantic Scholar
Measurement of PTEN by Flow Cytometry.
J. Woolley, L. Salmena
2016Methods in molecular biology2 citations
Semantic Scholar
Delineating the relationship between circulating osteoprotegerin and bone health in women with a pathogenic variant in BRCA1: A cross-sectional analysis
Aghaghia Mokhber, E. Hall, Aleksandra Uzelac, L. Salmena +4 more
2024Bone Reports1 citations Open access
Semantic Scholar
‘One way, or another, I’m gonna find ya’: miR-221-3p finds its targets via small extracellular vesicles
J. T. Chow, L. Salmena
2024Haematologica1 citations Open access
Semantic Scholar
The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate and Akt signalling
Victoria Chan, Leslie N. Bone, Karen E. Anderson, Kai Zhang +12 more
2023bioRxiv1 citations Open access
Semantic Scholar
INPP4B drives lysosome biogenesis to restrict leukemic stem cell differentiation and promote leukemogenesis
J. Woolley, Ke-Yue Chen, G. Saffi, G. Genç +22 more
2022bioRxiv1 citations Open access
Semantic Scholar
Faculty Opinions recommendation of Cancer/testis antigen-Plac1 promotes invasion and metastasis of breast cancer through Furin/NICD/PTEN signaling pathway.
L. Salmena
2020Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature1 citations Open access
Semantic Scholar
Author Correction: Exploring the coronavirus pandemic with the WashU Virus Genome Browser
Andrea Lunardi, U. Ala, M. Epping, L. Salmena +17 more
2020Nature Genetics1 citations Open access
Semantic Scholar
Inositol Polyphosphate-4-Phosphatase Type II promotes gemcitabine resistance in pancreatic ductal adenocarcinoma cells via lysosomal exocytosis
C. Melo, Candaice A. Newell, G. Saffi, Nathan Ng +5 more
2026bioRxiv0 citations Open access
Semantic Scholar
Abstract A039: Novel microRNA-mediated G2/M vulnerabilities in glioblastoma revealed by a CRISPR/Cas9 screen
I. Grigore, Athulram Rajagopal, Jonathan Tak-Sum Chow, Yu-Meng Zhou +3 more
2026Cancer Research0 citations
Semantic Scholar
When fibrinogen stops clotting and starts plotting: discovery of a new miRNA-GPCR axis in acute myeloid leukemia progression.
Byeong Yeop Lee, L. Salmena
2026Haematologica0 citations Open access
Semantic Scholar
A microRNA CRISPR screen reveals miR-483-3p as an apoptotic regulator in prostate cancer
J. T. Chow, Ayeisha Desjardins, Daniel K. C. Lee, I. Grigore +5 more
2025bioRxiv0 citations
Semantic Scholar
Abstract B042: A screen to identify modifiers of BRCA1 protein level for cancer prevention and treatment
E. Sellars, Margarita Savguira, J. Kotsopoulos, L. Salmena
2024Cancer Research0 citations
Semantic Scholar
The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling
Victoria Chan, Cristina Camardi, Kai Zhang, Laura A. Orofiamma +12 more
2024bioRxiv0 citations Open access
Semantic Scholar
Abstract P036: Circulating osteoprotegerin levels and breast cancer risk among women with a BRCA1 mutation: A prospective study
Shana J. Kim, Tasnim Zaman, Aleksandra Uzelac, P. Sun +4 more
2023Cancer Prevention Research0 citations
Semantic Scholar
Correlates of circulating osteoprotegerin in women with a pathogenic or likely pathogenic variant in the BRCA1 gene.
Sarah S Park, Tasnim Zaman, Shana J. Kim, Jennifer D Brooks +5 more
2023Cancer Epidemiology, Biomarkers and Prevention0 citations
Semantic Scholar
Abstract P037: Association between circulating osteoprotegerin levels and estimated risk of BRCA1-associated breast cancer
Sarah S Park, Tasnim Zaman, Shana J. Kim, Jennifer D. Brooks +5 more
2023Cancer Prevention Research0 citations
Semantic Scholar
Discovery of Essential microRNA in Prostate Cancer Cells
J. Chow, D. K. Lee, K. Chen, N. Fu +3 more
2022European Journal of Cancer0 citations Open access
Semantic Scholar
Identification of Global miRNA Targetomes within Human Hematopoietic Progenitors and Acute Myeloid Leukemia Uncovers Unique Molecular Networks Centered on Mitochondria Function in Leukemic Stem Cells
Gabriela Krivdova, Brian A. Yee, S. Aigner, M. Gabra +11 more
2022Blood0 citations Open access
Semantic Scholar
A 5-microRNA signature derived from core binding factor-AML is predictive in adult and childhood AML.
M. Gabra, J. Chow, TaeHyung Kim, M. Son +5 more
2022Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis0 citations
Semantic Scholar

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