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C. Pastrello · SciRah

Researcher profile · Semantic Scholar

C. Pastrello

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C. Pastrello — researcher profile on SciRah

h-index: 32
Works: 107
Citations: 3,413

Most-cited papers

mirDIP 4.1—integrative database of human microRNA target predictions
T. Tokár, C. Pastrello, Andrea E. M. Rossos, M. Abovsky +4 more
2017Nucleic Acids Res.510 citations Open access
Semantic Scholar
Mechanical Stiffness Controls Dendritic Cell Metabolism and Function.
M. Chakraborty, K. Chu, A. Shrestha, Xavier S. Revelo +22 more
2021Cell Reports233 citations Open access
Semantic Scholar
Integrated interactions database: tissue-specific view of the human and model organism interactomes
M. Kotlyar, C. Pastrello, Nicholas Sheahan, I. Jurisica
2015Nucleic Acids Res.222 citations Open access
Semantic Scholar
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set
N. del-Toro, M. Duesbury, M. Koch, L. Perfetto +13 more
2019Nature Communications203 citations Open access
Semantic Scholar
IID 2018 update: context-specific physical protein–protein interactions in human, model organisms and domesticated species
M. Kotlyar, C. Pastrello, Z. Malik, I. Jurisica
2018Nucleic Acids Res.183 citations Open access
Semantic Scholar
In silico prediction of physical protein interactions and characterization of interactome orphans
M. Kotlyar, C. Pastrello, Flavia Pivetta, A. L. Sardo +13 more
2014Nature Methods145 citations
Semantic Scholar
Molecular and Clinicopathologic Characterization of Gastrointestinal Stromal Tumors (GISTs) of Small Size
S. Rossi, D. Gasparotto, L. Toffolatti, C. Pastrello +14 more
2010American Journal of Surgical Pathology131 citations
Semantic Scholar
Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients.
C. Pastrello, J. Polesel, L. Della Puppa, A. Viel +1 more
2010Carcinogenesis105 citations
Semantic Scholar
pathDIP: an annotated resource for known and predicted human gene-pathway associations and pathway enrichment analysis
Sara Rahmati, M. Abovsky, C. Pastrello, I. Jurisica
2016Nucleic Acids Res.94 citations Open access
Semantic Scholar
Towards a unified open access dataset of molecular interactions
P. Porras, E. Barrera, A. Bridge, N. del-Toro +23 more
2020Nature Communications68 citations Open access
Semantic Scholar
pathDIP 4: an extended pathway annotations and enrichment analysis resource for human, model organisms and domesticated species
Sara Rahmati, M. Abovsky, C. Pastrello, M. Kotlyar +5 more
2019Nucleic Acids Res.63 citations Open access
Semantic Scholar
Sequencing identifies a distinct signature of circulating microRNAs in early radiographic knee osteoarthritis.
S. Ali, R. Gandhi, P. Potla, S. Keshavarzi +12 more
2020Osteoarthritis and Cartilage60 citations Open access
Semantic Scholar
Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease
Sergi Clotet-Freixas, O. Zaslaver, M. Kotlyar, C. Pastrello +38 more
2024Science Translational Medicine58 citations
Semantic Scholar
MirDIP 5.2: tissue context annotation and novel microRNA curation
Anne-Christin Hauschild, C. Pastrello, Gitta Kirana Anindya Ekaputeri, D. Bethune-Waddell +5 more
2022Nucleic Acids Res.56 citations Open access
Semantic Scholar
Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies
M. F. Rai, K. H. Collins, Annemarie Lang, Tristan Maerz +11 more
2023Osteoarthritis and Cartilage55 citations Open access
Semantic Scholar
A functional biological network centered on XRCC3: a new possible marker of chemoradiotherapy resistance in rectal cancer patients
M. Agostini, A. Zangrando, C. Pastrello, E. D'Angelo +15 more
2015Cancer Biology & Therapy54 citations Open access
Semantic Scholar
The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth
A. Paulitti, E. Andreuzzi, D. Bizzotto, R. Pellicani +15 more
2018Oncogene50 citations
Semantic Scholar
Proteomic and genomic profiling of plasma exosomes from patients with ankylosing spondylitis
F. Tavasolian, S. Lively, C. Pastrello, Michael Tang +8 more
2023Annals of the Rheumatic Diseases49 citations
Semantic Scholar
Prioritizing Therapeutics for Lung Cancer: An Integrative Meta-analysis of Cancer Gene Signatures and Chemogenomic Data
Kristen Fortney, Josh Griesman, M. Kotlyar, C. Pastrello +3 more
2015PLoS Comput. Biol.48 citations Open access
Semantic Scholar
IID 2021: towards context-specific protein interaction analyses by increased coverage, enhanced annotation and enrichment analysis
M. Kotlyar, C. Pastrello, Zuhaib Ahmed, Justin Chee +2 more
2021Nucleic Acids Res.46 citations Open access
Semantic Scholar
An integrated approach identifies mediators of local recurrence in Head & Neck Squamous Carcinoma
F. Citron, J. Armenia, G. Franchin, J. Polesel +17 more
2017Clinical Cancer Research44 citations Open access
Semantic Scholar
TP53 mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses
V. Mandilaras, S. Garg, M. Cabanero, Qian Tan +14 more
2019International Journal of Gynecologic Cancer43 citations Open access
Semantic Scholar
An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer
Marco Agostini, K. Janssen, ll-Jin Kim, E. D'Angelo +13 more
2015OncoTarget40 citations Open access
Semantic Scholar
Integrated analysis of unclassified variants in mismatch repair genes
C. Pastrello, E. Pin, F. Marroni, C. Bedin +8 more
2011Genetics in Medicine40 citations Open access
Semantic Scholar
The IMEx coronavirus interactome: an evolving map of Coronaviridae–host molecular interactions
L. Perfetto, C. Pastrello, N. del-Toro, M. Duesbury +16 more
2020bioRxiv38 citations Open access
Semantic Scholar
A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency.
K. Kaufmann, Laura Garcia-Prat, Qiang Liu, Stanley W. K. Ng +16 more
2019Blood38 citations Open access
Semantic Scholar
Extracellular Matrix Injury of Kidney Allografts in Antibody-Mediated Rejection: A Proteomics Study.
Sergi Clotet-Freixas, C. Mcevoy, Ihor Batruch, C. Pastrello +22 more
2020Journal of the American Society of Nephrology37 citations Open access
Semantic Scholar
Drugst.One — a plug-and-play solution for online systems medicine and network-based drug repurposing
Andreas Maier, Michael Hartung, M. Abovsky, Klaudia Adamowicz +36 more
2024Nucleic Acids Research32 citations Open access
Semantic Scholar
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis
Li Li, K. K. N. Guturi, Brandon Gautreau, Parasvi S. Patel +19 more
2018Journal of Clinical Investigation32 citations Open access
Semantic Scholar
Integration, visualization and analysis of human interactome.
C. Pastrello, E. Pasini, M. Kotlyar, D. Otasek +4 more
2014Biochemical and Biophysical Research Communications - BBRC32 citations
Semantic Scholar
Circulating plant miRNAs can regulate human gene expression in vitro
C. Pastrello, Mike J. Tsay, Rosanne McQuaid, M. Abovsky +10 more
2016Scientific Reports30 citations Open access
Semantic Scholar
Estrogen Receptor 1 Inhibition of Wnt/β-Catenin Signaling Contributes to Sex Differences in Hepatocarcinogenesis
M. Bhat, E. Pasini, C. Pastrello, M. Angeli +6 more
2021Frontiers in Oncology29 citations Open access
Semantic Scholar
Circulating microRNAs differentiate fast-progressing from slow-progressing and non-progressing knee osteoarthritis in the Osteoarthritis Initiative cohort
S. Ali, O. Espin-Garcia, A. K. Wong, P. Potla +6 more
2022Therapeutic Advances in Musculoskeletal Disease28 citations Open access
Semantic Scholar
PathDIP 5: improving coverage and making enrichment analysis more biologically meaningful
C. Pastrello, M. Kotlyar, M. Abovsky, Richard Lu +1 more
2023Nucleic Acids Research27 citations Open access
Semantic Scholar
Visual Data Mining of Biological Networks: One Size Does Not Fit All
C. Pastrello, D. Otasek, Kristen Fortney, Giuseppe Agapito +3 more
2013PLoS Comput. Biol.27 citations Open access
Semantic Scholar
Visual Data Mining: Effective Exploration of the Biological Universe
D. Otasek, C. Pastrello, Andreas Holzinger, I. Jurisica
2014Interactive Knowledge Discovery and Data Mining in Biomedical Informatics25 citations
Semantic Scholar
BioPAX-Parser: parsing and enrichment analysis of BioPAX pathways
Giuseppe Agapito, C. Pastrello, P. Guzzi, I. Jurisica +1 more
2020Bioinform.21 citations Open access
Semantic Scholar
Evolution and advancements in genomics and epigenomics in OA research: How far we have come.
Y. Ramos, Sarah J. Rice, S. A. Ali, C. Pastrello +11 more
2024Osteoarthritis and Cartilage19 citations Open access
Semantic Scholar
Informed Use of Protein-Protein Interaction Data: A Focus on the Integrated Interactions Database (IID)
C. Pastrello, M. Kotlyar, I. Jurisica
2020Protein-Protein Interaction Networks16 citations
Semantic Scholar
MUTYH c.933+3A>C, associated with a severely impaired gene expression, is the first Italian founder mutation in MUTYH‐Associated Polyposis
E. Pin, C. Pastrello, R. Tricarico, L. Papi +11 more
2013International Journal of Cancer16 citations Open access
Semantic Scholar
Tumor cell endogenous HIF-1α activity induces aberrant angiogenesis and interacts with TRAF6 pathway required for colorectal cancer development
Jesus F. Glaus Garzon, C. Pastrello, I. Jurisica, M. Hottiger +2 more
2020Neoplasia15 citations Open access
Semantic Scholar
Vesicular traffic-mediated cell-to-cell signaling at the immune synapse in Ankylosing Spondylitis
F. Tavasolian, C. Pastrello, Zuhaib Ahmed, I. Jurisica +1 more
2023Frontiers in Immunology14 citations Open access
Semantic Scholar
Increased Autoantibodies Against Ro/SS-A, CENP-B, and La/SS-B in Patients With Kidney Allograft Antibody-mediated Rejection
Sergi Clotet-Freixas, M. Kotlyar, C. Mcevoy, C. Pastrello +14 more
2021Transplantation Direct13 citations Open access
Semantic Scholar
Normothermic Ex-vivo Kidney Perfusion in a Porcine Auto-Transplantation Model Preserves the Expression of Key Mitochondrial Proteins: An Unbiased Proteomics Analysis
C. Mcevoy, Sergi Clotet-Freixas, T. Tokár, C. Pastrello +13 more
2020bioRxiv13 citations Open access
Semantic Scholar
GSOAP: a tool for visualization of gene set over-representation analysis
T. Tokár, C. Pastrello, I. Jurisica
2020Bioinform.13 citations Open access
Semantic Scholar
SDREGION: Fast Spotting of Changing Communities in Biological Networks
Serene W. H. Wong, C. Pastrello, M. Kotlyar, C. Faloutsos +1 more
2018Knowledge Discovery and Data Mining13 citations Open access
Semantic Scholar
Robust quantitative scratch assay
Andrea Vargas, M. Angeli, C. Pastrello, Rosanne McQuaid +3 more
2015Bioinform.13 citations Open access
Semantic Scholar
Proximal and classic epithelioid sarcomas are distinct molecular entities defined by MYC/GATA3 and SOX17/endothelial markers, respectively.
L. Sigalotti, A. Frezza, M. Sbaraglia, Elisa Del Savio +22 more
2024Modern Pathology11 citations Open access
Semantic Scholar
Comprehensive pathway enrichment analysis workflows: COVID-19 case study
Giuseppe Agapito, C. Pastrello, I. Jurisica
2020Briefings Bioinform.11 citations Open access
Semantic Scholar
Osteoarthritis Data Integration Portal (OsteoDIP): A web-based gene and non-coding RNA expression database
C. Pastrello, M. Abovsky, Richard Lu, Zuhaib Ahmed +3 more
2022Osteoarthritis and Cartilage Open10 citations Open access
Semantic Scholar

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