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E. Deuerling · SciRah

Researcher profile · Semantic Scholar

E. Deuerling

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E. Deuerling — researcher profile on SciRah

h-index: 41
Works: 89
Citations: 6,761

Most-cited papers

Trigger factor and DnaK cooperate in folding of newly synthesized proteins
E. Deuerling, A. Schulze‐Specking, T. Tomoyasu, A. Mogk +1 more
1999Nature524 citations Open access
Semantic Scholar
Getting Newly Synthesized Proteins Minireview into Shape
B. Bukau, E. Deuerling, Christine Pfund, E. Craig
2000428 citations
Semantic Scholar
Trigger factor in complex with the ribosome forms a molecular cradle for nascent proteins
L. Ferbitz, T. Maier, H. Patzelt, B. Bukau +2 more
2004Nature427 citations Open access
Semantic Scholar
Small heat shock proteins, ClpB and the DnaK system form a functional triade in reversing protein aggregation
A. Mogk, E. Deuerling, S. Vorderwülbecke, E. Vierling +1 more
2003Molecular Microbiology377 citations Open access
Semantic Scholar
L23 protein functions as a chaperone docking site on the ribosome
G. Kramer, T. Rauch, W. Rist, S. Vorderwülbecke +5 more
2002Nature362 citations Open access
Semantic Scholar
Chaperone-based procedure to increase yields of soluble recombinant proteins produced in E. coli
A. de Marco, E. Deuerling, A. Mogk, T. Tomoyasu +1 more
2007BMC Biotechnology306 citations Open access
Semantic Scholar
A dual function for chaperones SSB–RAC and the NAC nascent polypeptide–associated complex on ribosomes
Ansgar Koplin, S. Preissler, Y. Ilina, M. Koch +3 more
2010Journal of Cell Biology228 citations Open access
Semantic Scholar
Trigger Factor and DnaK possess overlapping substrate pools and binding specificities
E. Deuerling, H. Patzelt, S. Vorderwülbecke, T. Rauch +6 more
2003Molecular Microbiology206 citations Open access
Semantic Scholar
Ribosome-associated chaperones as key players in proteostasis.
S. Preissler, E. Deuerling
2012TIBS -Trends in Biochemical Sciences. Regular ed193 citations
Semantic Scholar
Binding specificity of Escherichia coli trigger factor
H. Patzelt, S. Rüdiger, Dirk Brehmer, G. Kramer +8 more
2001Proceedings of the National Academy of Sciences of the United States of America188 citations Open access
Semantic Scholar
Molecular mechanism and structure of Trigger Factor bound to the translating ribosome
F. Merz, D. Boehringer, C. Schaffitzel, S. Preissler +7 more
2008EMBO Journal176 citations Open access
Semantic Scholar
The nascent polypeptide‐associated complex is a key regulator of proteostasis
Janine Kirstein‐Miles, Annika Scior, E. Deuerling, Richard I. Morimoto
2013EMBO Journal168 citations Open access
Semantic Scholar
The principle of antagonism ensures protein targeting specificity at the endoplasmic reticulum
M. Gamerdinger, M. A. Hanebuth, T. Frickey, E. Deuerling
2015Science142 citations
Semantic Scholar
The ftsH gene of Bacillus subtilis is involved in major cellular processes such as sporulation, stress adaptation and secretion
E. Deuerling, A. Mogk, Carolin G. Richter, Martina Purucker +1 more
1997Molecular Microbiology135 citations Open access
Semantic Scholar
Chaperone-Assisted Folding of Newly Synthesized Proteins in the Cytosol
E. Deuerling, B. Bukau
2004Critical reviews in biochemistry and molecular biology125 citations Open access
Semantic Scholar
Concerted action of the ribosome and the associated chaperone trigger factor confines nascent polypeptide folding.
Anja Hoffmann, A. H. Becker, B. Zachmann-Brand, E. Deuerling +2 more
2012Molecules and Cells119 citations Open access
Semantic Scholar
Trigger Factor Peptidyl-prolyl cis/trans Isomerase Activity Is Not Essential for the Folding of Cytosolic Proteins in Escherichia coli*
G. Kramer, H. Patzelt, T. Rauch, T. A. Kurz +3 more
2004Journal of Biological Chemistry116 citations Open access
Semantic Scholar
Low temperature or GroEL/ES overproduction permits growth of Escherichia coli cells lacking trigger factor and DnaK
S. Vorderwülbecke, G. Kramer, F. Merz, T. A. Kurz +4 more
2004FEBS Letters114 citations Open access
Semantic Scholar
A cradle for new proteins: trigger factor at the ribosome.
T. Maier, L. Ferbitz, E. Deuerling, N. Ban
2005Current Opinion in Structural Biology112 citations Open access
Semantic Scholar
The Amino-terminal 118 Amino Acids of Escherichia coli Trigger Factor Constitute a Domain That Is Necessary and Sufficient for Binding to Ribosomes*
T. Hesterkamp, E. Deuerling, B. Bukau
1997Journal of Biological Chemistry109 citations Open access
Semantic Scholar
Dynamics of Trigger Factor Interaction with Translating Ribosomes*
A. Rutkowska, Matthias P. Mayer, Anja Hoffmann, F. Merz +5 more
2008Journal of Biological Chemistry108 citations Open access
Semantic Scholar
Three-State Equilibrium of Escherichia coli Trigger Factor
Holger Patzelt, G. Kramer, T. Rauch, H. Schönfeld +2 more
2002Biological chemistry107 citations Open access
Semantic Scholar
Molecular guardians for newborn proteins: ribosome-associated chaperones and their role in protein folding
Renee D. Wegrzyn, E. Deuerling
2005Cellular and Molecular Life Sciences (CMLS)102 citations Open access
Semantic Scholar
The C-terminal Domain of Escherichia coli Trigger Factor Represents the Central Module of Its Chaperone Activity*
F. Merz, Anja Hoffmann, A. Rutkowska, B. Zachmann-Brand +2 more
2006Journal of Biological Chemistry101 citations
Semantic Scholar
Trigger Factor Forms a Protective Shield for Nascent Polypeptides at the Ribosome*
Anja Hoffmann, F. Merz, A. Rutkowska, B. Zachmann-Brand +2 more
2006Journal of Biological Chemistry100 citations Open access
Semantic Scholar
Functional Dissection of Escherichia coli Trigger Factor: Unraveling the Function of Individual Domains
G. Kramer, A. Rutkowska, Renee D. Wegrzyn, Holger Patzelt +6 more
2004Journal of Bacteriology99 citations Open access
Semantic Scholar
Mechanisms of Protein Folding: Molecular Chaperones and Their Application in Biotechnology
A. Mogk, Matthias P. Mayer, E. Deuerling
2002ChemBioChem99 citations Open access
Semantic Scholar
A Conserved Motif Is Prerequisite for the Interaction of NAC with Ribosomal Protein L23 and Nascent Chains*
Renee D. Wegrzyn, D. Hofmann, F. Merz, R. Nikolay +3 more
2006Journal of Biological Chemistry98 citations Open access
Semantic Scholar
Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopy
Cédric Eichmann, S. Preissler, R. Riek, E. Deuerling
2010Proceedings of the National Academy of Sciences of the United States of America96 citations Open access
Semantic Scholar
Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting
A. Jomaa, M. Gamerdinger, Hao-Hsuan Hsieh, Ann-Kathrin Wallisch +7 more
2022Microscopy and Microanalysis94 citations Open access
Semantic Scholar
Chaperone Interactions at the Ribosome.
E. Deuerling, M. Gamerdinger, Stefan G. Kreft
2019Cold Spring Harbor Perspectives in Biology91 citations Open access
Semantic Scholar
Trigger factor binds to ribosome-signal-recognition particle (SRP) complexes and is excluded by binding of the SRP receptor.
Iwona A. Buskiewicz, E. Deuerling, Shan-Qing Gu, Johannes Jöckel +3 more
2004Proceedings of the National Academy of Sciences of the United States of America91 citations Open access
Semantic Scholar
The ftsH gene of Bacillus subtilis is transiently induced after osmotic and temperature upshift
E. Deuerling, Bettina Paeslack, W. Schumann
1995Journal of Bacteriology90 citations Open access
Semantic Scholar
Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC.
M. Gamerdinger, K. Kobayashi, A. Wallisch, Stefan G. Kreft +7 more
2019Molecules and Cells83 citations Open access
Semantic Scholar
Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
R. Nikolay, T. Hilal, S. Schmidt, B. Qin +11 more
2021Molecules and Cells67 citations Open access
Semantic Scholar
Functional Dissection of Trigger Factor and DnaK: Interactions with Nascent Polypeptides and Thermally Denatured Proteins
Elke Schaffitzel, S. Rüdiger, B. Bukau, E. Deuerling
2001Biological chemistry59 citations Open access
Semantic Scholar
Not4‐dependent translational repression is important for cellular protein homeostasis in yeast
S. Preissler, J. Reuther, M. Koch, Annika Scior +3 more
2015EMBO Journal58 citations Open access
Semantic Scholar
Cotranslational sorting and processing of newly synthesized proteins in eukaryotes.
M. Gamerdinger, E. Deuerling
2023TIBS -Trends in Biochemical Sciences. Regular ed53 citations Open access
Semantic Scholar
NAC controls cotranslational N-terminal methionine excision in eukaryotes
M. Gamerdinger, Min Jia, Renate Schloemer, Laurenz Rabl +10 more
2023Science48 citations
Semantic Scholar
Directed PCR-free engineering of highly repetitive DNA sequences
Annika Scior, S. Preissler, M. Koch, E. Deuerling
2011BMC Biotechnology48 citations Open access
Semantic Scholar
Insights into the Aggregation Mechanism of PolyQ Proteins with Different Glutamine Repeat Lengths.
T. Yushchenko, E. Deuerling, K. Hauser
2018Biophysical Journal47 citations Open access
Semantic Scholar
Molecular basis of the TRAP complex function in ER protein biogenesis
M. Jaskolowski, A. Jomaa, M. Gamerdinger, Sandeep Shrestha +3 more
2022bioRxiv39 citations Open access
Semantic Scholar
NAC guides a ribosomal multienzyme complex for nascent protein processing
A. Lentzsch, D. Yudin, M. Gamerdinger, S. Chandrasekar +5 more
2024Nature36 citations
Semantic Scholar
Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies
Ko-Ning Shen, M. Gamerdinger, Rebecca Chan, Karina Gense +11 more
2019Molecules and Cells35 citations Open access
Semantic Scholar
Structural Analysis of the Ribosome-associated Complex (RAC) Reveals an Unusual Hsp70/Hsp40 Interaction*
Jocelyne Fiaux, J. Horst, Annika Scior, S. Preissler +3 more
2009Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Functional Dissection of the Nascent Polypeptide-Associated Complex in Saccharomyces cerevisiae
A. Ott, L. Locher, M. Koch, E. Deuerling
2015PLoS ONE30 citations Open access
Semantic Scholar
Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction
M. A. Hanebuth, Roman Kityk, Sandra J Fries, Alok Jain +7 more
2016Nature Communications28 citations Open access
Semantic Scholar
Target-directed proteolysis at the ribosome.
T. Henrichs, N. Mikhaleva, Charlotte Conz, E. Deuerling +5 more
2005Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
Dissecting functional similarities of ribosome‐associated chaperones from Saccharomyces cerevisiae and Escherichia coli
T. Rauch, H. Hundley, Christine Pfund, Renee D. Wegrzyn +5 more
2005Molecular Microbiology24 citations Open access
Semantic Scholar
Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins
Esther M. Martin, M. P. Jackson, M. Gamerdinger, Karina Gense +5 more
2018Journal of Biological Chemistry23 citations Open access
Semantic Scholar

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