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M. L. Giuffrida · SciRah

Researcher profile · Semantic Scholar

M. L. Giuffrida

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M. L. Giuffrida — researcher profile on SciRah

h-index: 25
Works: 60
Citations: 1,833

Most-cited papers

β-Amyloid Monomers Are Neuroprotective
M. L. Giuffrida, F. Caraci, B. Pignataro, S. Cataldo +10 more
2009Journal of Neuroscience349 citations Open access
Semantic Scholar
TGF‐β1 Pathway as a New Target for Neuroprotection in Alzheimer's Disease
F. Caraci, G. Battaglia, V. Bruno, P. Bosco +6 more
2011CNS Neuroscience & Therapeutics129 citations Open access
Semantic Scholar
Targeting Group II Metabotropic Glutamate (mGlu) Receptors for the Treatment of Psychosis Associated with Alzheimer's Disease: Selective Activation of mGlu2 Receptors Amplifies β-Amyloid Toxicity in Cultured Neurons, Whereas Dual Activation of mGlu2 and mGlu3 Receptors Is Neuroprotective
F. Caraci, G. Molinaro, G. Battaglia, M. L. Giuffrida +13 more
2011Molecular Pharmacology114 citations
Semantic Scholar
The Monomer State of Beta-Amyloid: Where the Alzheimer's Disease Protein Meets Physiology
M. L. Giuffrida, F. Caraci, P. de Bona, Giuseppe Pappalardo +3 more
2010Reviews in the Neurosciences87 citations
Semantic Scholar
Gluconjugates of 8-hydroxyquinolines as potential anti-cancer prodrugs.
V. Oliveri, M. L. Giuffrida, G. Vecchio, C. Aiello +1 more
2012Dalton Transactions62 citations
Semantic Scholar
Silencing of endogenous IGFBP-5 by micro RNA interference affects proliferation, apoptosis and differentiation of neuroblastoma cells
B. Tanno, V. Cesi, R. Vitali, Fabiola Sesti +4 more
2005Cell Death and Differentiation58 citations Open access
Semantic Scholar
Carnosine interaction with nitric oxide and astroglial cell protection
V. Nicoletti, A. Santoro, G. Grasso, Laura Irene Vagliasindi +5 more
2007Journal of Neuroscience Research56 citations
Semantic Scholar
Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type‐1 insulin‐like growth factor receptors in neuronal cells
S. Zimbone, I. Monaco, F. Gianì, G. Pandini +3 more
2017Aging Cell51 citations Open access
Semantic Scholar
A promising connection between BDNF and Alzheimer’s disease
M. L. Giuffrida, A. Copani, E. Rizzarelli
2018Aging50 citations Open access
Semantic Scholar
Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons
M. L. Giuffrida, M. Tomasello, G. Pandini, F. Caraci +13 more
2015Frontiers in Cellular Neuroscience50 citations Open access
Semantic Scholar
Neurotoxic properties of the anabolic androgenic steroids nandrolone and methandrostenolone in primary neuronal cultures
F. Caraci, V. Pistarà, A. Corsaro, F. Tomasello +4 more
2011Journal of Neuroscience Research49 citations
Semantic Scholar
A novel fully water-soluble Cu(I) probe for fluorescence live cell imaging.
M. L. Giuffrida, E. Rizzarelli, G. A. Tomaselli, C. Satriano +1 more
2014Chemical Communications43 citations
Semantic Scholar
A ratiometric naphthalimide sensor for live cell imaging of copper(I).
C. Satriano, Giuseppe Trusso Sfrazzetto, M. Amato, F. P. Ballistreri +7 more
2013Chemical Communications42 citations
Semantic Scholar
A New Ratiometric Lysosomal Copper(II) Fluorescent Probe To Map a Dynamic Metallome in Live Cells.
M. L. Giuffrida, Giuseppe Trusso Sfrazzetto, C. Satriano, S. Zimbone +3 more
2018Inorganic Chemistry41 citations
Semantic Scholar
Beta-Amyloid Monomer and Insulin/IGF-1 Signaling in Alzheimer's Disease
M. L. Giuffrida, F. Tomasello, F. Caraci, S. Chiechio +2 more
2012Molecular Neurobiology38 citations
Semantic Scholar
Aβ(25–35) and its C‐ and/or N‐blocked derivatives: Copper driven structural features and neurotoxicity
M. L. Giuffrida, G. Grasso, M. Ruvo, C. Pedone +6 more
2007Journal of Neuroscience Research37 citations
Semantic Scholar
Metallostasis and amyloid β-degrading enzymes.
G. Grasso, M. L. Giuffrida, E. Rizzarelli
2012Metallomics36 citations
Semantic Scholar
Cyclin D1-dependent regulation of B-myb activity in early stages of neuroblastoma differentiation
V. Cesi, B. Tanno, R. Vitali, Camillo Mancini +3 more
2002Cell Death and Differentiation32 citations Open access
Semantic Scholar
Green Light-Triggerable Chemo-Photothermal Activity of Cytarabine-Loaded Polymer Carbon Dots: Mechanism and Preliminary In Vitro Evaluation
G. M. L. Consoli, M. L. Giuffrida, S. Zimbone, Loredana Ferreri +5 more
2023ACS Applied Materials and Interfaces31 citations Open access
Semantic Scholar
Ratiometric fluorescence sensing and cellular imaging of Cu2+ by a new water soluble trehalose-naphthalimide based chemosensor
G. Grasso, S. Gentile, M. L. Giuffrida, C. Satriano +5 more
201330 citations
Semantic Scholar
Ac‐LPFFD‐Th: A Trehalose‐Conjugated Peptidomimetic as a Strong Suppressor of Amyloid‐β Oligomer Formation and Cytotoxicity
A. Sinopoli, A. Giuffrida, M. Tomasello, M. L. Giuffrida +9 more
2016ChemBioChem29 citations
Semantic Scholar
Trehalose conjugates of silybin as prodrugs for targeting toxic Aβ aggregates.
S. García‐Viñuales, Rashik Ahmed, M. Sciacca, V. Lanza +10 more
2020ACS Chemical Neuroscience28 citations
Semantic Scholar
Enhanced expression of ERalpha in astrocytes modifies the response of cortical neurons to beta-amyloid toxicity.
V. Carbonaro, F. Caraci, M. L. Giuffrida, S. Merlo +4 more
2009Neurobiology of Disease28 citations Open access
Semantic Scholar
Porphyrin Cyclodextrin Conjugates Modulate Amyloid Beta Peptide Aggregation and Cytotoxicity.
V. Oliveri, S. Zimbone, M. L. Giuffrida, F. Bellia +2 more
2018Chemistry26 citations
Semantic Scholar
Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity.
S. Merlo, L. Basile, M. L. Giuffrida, M. Sortino +2 more
2015Journal of Natural Products25 citations
Semantic Scholar
Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: a comparative study with the respective full-length parent polypeptides.
M. Tomasello, A. Sinopoli, F. Attanasio, M. L. Giuffrida +3 more
2014European journal of medicinal chemistry25 citations
Semantic Scholar
Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity.
F. Caraci, G. Pappalardo, L. Basile, A. Giuffrida +8 more
2015European Journal of Pharmacology23 citations
Semantic Scholar
KLVFF oligopeptide-decorated amphiphilic cyclodextrin nanomagnets for selective amyloid beta recognition and fishing.
A. Mazzaglia, G. Di Natale, Rita Tosto, A. Scala +9 more
2022Journal of Colloid and Interface Science22 citations Open access
Semantic Scholar
Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ’s Oligomers Cytotoxicity In Vitro
G. M. L. Consoli, Rita Tosto, Ausilia Baglieri, S. Petralia +5 more
2021ACS Chemical Neuroscience22 citations Open access
Semantic Scholar
β-amyloid monomers drive up neuronal aerobic glycolysis in response to energy stressors
R. Santangelo, M. L. Giuffrida, C. Satriano, M. Tomasello +2 more
2021Aging20 citations Open access
Semantic Scholar
Exploring the Role of Hsp60 in Alzheimer’s Disease and Type 2 Diabetes: Suggestion for Common Drug Targeting
S. Zimbone, M. D. Di Rosa, S. Chiechio, M. L. Giuffrida
2023International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer’s Disease
E. Simoni, R. Caporaso, C. Bergamini, J. Fiori +9 more
2016ACS Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
C/EBP α and β mimic retinoic acid activation of IGFBP-5 in neuroblastoma cells by a mechanism independent from binding to their site
V. Cesi, M. L. Giuffrida, R. Vitali, B. Tanno +3 more
200516 citations Open access
Semantic Scholar
Electrostatically driven interaction of silica-supported lipid bilayer nanoplatforms and a nerve growth factor-mimicking peptide
Alessio Travaglia, C. Satriano, M. L. Giuffrida, D. La Mendola +3 more
201315 citations
Semantic Scholar
VDAC1‐Targeted NHK1 Peptide Recovers Mitochondrial Dysfunction Counteracting Amyloid‐β Oligomers Toxicity in Alzheimer's Disease
F. Cavallaro, Stefano Conti Nibali, S. M. Cubisino, Pietro Caruso +7 more
2025Aging Cell14 citations Open access
Semantic Scholar
Exploring the therapeutic potential of Aloin: unraveling neuroprotective and anticancer mechanisms, and strategies for enhanced stability and delivery
S. Zimbone, V. Romanucci, A. Zarrelli, M. L. Giuffrida +8 more
2024Scientific Reports14 citations Open access
Semantic Scholar
Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models
M. Sciacca, Irina Naletova, M. L. Giuffrida, F. Attanasio
2022ACS Chemical Neuroscience14 citations Open access
Semantic Scholar
Potential therapeutics of Alzheimer's diseases: New insights into the neuroprotective role of trehalose‐conjugated beta sheet breaker peptides
G. Di Natale, S. Zimbone, F. Bellia, M. Tomasello +3 more
2018Peptide Science14 citations
Semantic Scholar
A novel material based on an antibacterial choline-calixarene nanoassembly embedded in thin films
Loredana Ferreri, G. M. L. Consoli, G. Clarizia, D. Zampino +6 more
2022Journal of Materials Science13 citations Open access
Semantic Scholar
Aβ8-20 Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer’s Disease Treatment
S. Zimbone, M. L. Giuffrida, Giuseppina Sabatino, G. Di Natale +5 more
2023ACS Chemical Neuroscience12 citations Open access
Semantic Scholar
Insulin‐like Growth Factor Binding Protein 5: Contribution to Growth and Differentiation of Neuroblastoma Cells
V. Cesi, R. Vitali, B. Tanno, M. L. Giuffrida +3 more
2004Annals of the New York Academy of Sciences12 citations
Semantic Scholar
A novel facile one-pot synthesis of photothermally responsive carbon polymer dots as promising drug nanocarriers.
G. M. L. Consoli, M. L. Giuffrida, C. Satriano, T. Musumeci +2 more
2022Chemical Communications11 citations
Semantic Scholar
Red-Light-Photosensitized Tyrosine 10 Nitration of β-Amyloid1-42 Diverts the Protein from Forming Toxic Aggregates.
Sarah Basile, Cristina Parisi, F. Bellia, S. Zimbone +6 more
2024ACS Chemical Neuroscience7 citations Open access
Semantic Scholar
C/EBP alpha and beta mimic retinoic acid activation of IGFBP-5 in neuroblastoma cells by a mechanism independent from binding to their site.
V. Cesi, M. L. Giuffrida, R. Vitali, B. Tanno +3 more
2005Experimental Cell Research7 citations
Semantic Scholar
Memantine and Amantadine KLVFF peptide conjugates: Synthesis, structure determination, amyloid-β interaction and effects on recognition memory in mice.
Eleonora Bocchieri, S. Zimbone, M. L. Giuffrida, G. Di Natale +4 more
2025European Journal of Pharmacology6 citations Open access
Semantic Scholar
Amyloid β and Alzheimer’s Disease: Molecular Updates from Physiology to Pathology
M. L. Giuffrida
2023International Journal of Molecular Sciences6 citations Open access
Semantic Scholar
Molecular Connections between DNA Replication and Cell Death in β-Amyloid-Treated Neurons
F. Caraci, A. Fidilio, R. Santangelo, Giuseppe Caruso +4 more
2023Current Neuropharmacology6 citations Open access
Semantic Scholar
Investigation on the solid-phase synthesis of silybin prodrugs and their timed-release.
V. Romanucci, Maddalena Giordano, Rita Pagano, S. Zimbone +4 more
2021Bioorganic & Medicinal Chemistry5 citations
Semantic Scholar
A VEGF Fragment Encompassing Residues 10-30 Inhibits Aβ1-42 Amyloid Aggregation and Exhibits Neuroprotective Properties Matching the Full-Length Protein.
S. Zimbone, M. L. Giuffrida, M. Sciacca, R. Carrotta +3 more
2024ACS Chemical Neuroscience3 citations
Semantic Scholar
A zinc–porphyrin–peptide conjugate via “click-chemistry”: synthesis and amyloid-β interaction
Rita Tosto, S. Zimbone, G. Di Natale, M. L. Giuffrida +3 more
2024New Journal of Chemistry3 citations Open access
Semantic Scholar

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A. Copani×19
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A. Copani — researcher profile on SciRah
S. Zimbone×18
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S. Zimbone — researcher profile on SciRah
E. Rizzarelli×14
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E. Rizzarelli — researcher profile on SciRah
F. Caraci×12
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G. Pappalardo — researcher profile on SciRah

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M. Tomasello×7

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M. Tomasello — researcher profile on SciRah

F. Nicoletti×6

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F. Nicoletti — researcher profile on SciRah

G. M. L. Consoli×6

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G. M. L. Consoli — researcher profile on SciRah

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M. Sortino — researcher profile on SciRah

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B. Tanno — researcher profile on SciRah