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G. Pandini · SciRah

Researcher profile · Semantic Scholar

G. Pandini

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G. Pandini — researcher profile on SciRah

h-index: 35
Works: 64
Citations: 6,749

Most-cited papers

Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.
A. Belfiore, F. Frasca, G. Pandini, L. Sciacca +1 more
2009Endocrine reviews1,027 citations
Semantic Scholar
Insulin Receptor Isoform A, a Newly Recognized, High-Affinity Insulin-Like Growth Factor II Receptor in Fetal and Cancer Cells
F. Frasca, G. Pandini, Pierluigi Scalia, L. Sciacca +5 more
1999Molecular and Cellular Biology933 citations Open access
Semantic Scholar
Insulin/Insulin-like Growth Factor I Hybrid Receptors Have Different Biological Characteristics Depending on the Insulin Receptor Isoform Involved*
G. Pandini, F. Frasca, R. Mineo, L. Sciacca +2 more
2002Journal of Biological Chemistry509 citations Open access
Semantic Scholar
The role of insulin receptors and IGF-I receptors in cancer and other diseases
F. Frasca, G. Pandini, L. Sciacca, V. Pezzino +3 more
2008Archives of Physiology and Biochemistry445 citations
Semantic Scholar
Diabetes and cancer.
P. Vigneri, F. Frasca, L. Sciacca, G. Pandini +1 more
2009Endocrine-Related Cancer408 citations Open access
Semantic Scholar
Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism
L. Sciacca, A. Costantino, G. Pandini, R. Mineo +6 more
1999Oncogene300 citations
Semantic Scholar
Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling.
G. Pandini, R. Vigneri, A. Costantino, F. Frasca +5 more
1999Clinical Cancer Research276 citations
Semantic Scholar
A novel autocrine loop involving IGF-II and the insulin receptor isoform-A stimulates growth of thyroid cancer.
V. Vella, G. Pandini, L. Sciacca, R. Mineo +3 more
2002Journal of Clinical Endocrinology and Metabolism247 citations Open access
Semantic Scholar
Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells.
G. Pandini, R. Mineo, F. Frasca, C. Roberts +3 more
2005Cancer Research208 citations Open access
Semantic Scholar
The IGF system in thyroid cancer: new concepts
V. Vella, L. Sciacca, G. Pandini, R. Mineo +3 more
2001Molecular Pathology185 citations Open access
Semantic Scholar
In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A
L. Sciacca, R. Mineo, G. Pandini, Antonella Murabito +2 more
2002Oncogene174 citations Open access
Semantic Scholar
Insulin receptor isoforms and insulin-like growth factor receptor in human follicular cell precursors from papillary thyroid cancer and normal thyroid.
R. Malaguarnera, F. Frasca, A. Garozzo, F. Gianì +4 more
2011Journal of Clinical Endocrinology and Metabolism154 citations
Semantic Scholar
Efficacy of and resistance to anti-IGF-1R therapies in Ewing's sarcoma is dependent on insulin receptor signaling
C. Garofalo, M. Manara, G. Nicoletti, M. Marino +8 more
2011Oncogene145 citations Open access
Semantic Scholar
Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling
L. Sciacca, M. Cassarino, M. Genua, G. Pandini +3 more
2010Diabetologia138 citations Open access
Semantic Scholar
Insulin/IGF-I hybrid receptors play a major role in IGF-I signaling in thyroid cancer.
A. Belfiore, G. Pandini, V. Vella, S. Squatrito +1 more
1999Biochimie109 citations
Semantic Scholar
Peroxisomal proliferator-activated receptor-gamma agonists induce partial reversion of epithelial-mesenchymal transition in anaplastic thyroid cancer cells.
A. Aiello, G. Pandini, F. Frasca, Enrico Conte +5 more
2006Endocrinology107 citations Open access
Semantic Scholar
Proinsulin binds with high affinity the insulin receptor isoform A and predominantly activates the mitogenic pathway.
R. Malaguarnera, A. Sacco, C. Voci, G. Pandini +2 more
2012Endocrinology102 citations
Semantic Scholar
Differential Gene Expression Induced by Insulin and Insulin-like Growth Factor-II through the Insulin Receptor Isoform A*
G. Pandini, E. Medico, Enrico Conte, L. Sciacca +2 more
2003Journal of Biological Chemistry96 citations Open access
Semantic Scholar
Insulin has multiple antiamyloidogenic effects on human neuronal cells.
G. Pandini, Vincenza Pace, A. Copani, S. Squatrito +2 more
2013Endocrinology92 citations Open access
Semantic Scholar
Differential signaling activation by insulin and insulin-like growth factors I and II upon binding to insulin receptor isoform A.
A. Sacco, A. Morcavallo, G. Pandini, R. Vigneri +1 more
2009Endocrinology79 citations Open access
Semantic Scholar
Functional responses and in vivo anti-tumour activity of h7C10: a humanised monoclonal antibody with neutralising activity against the insulin-like growth factor-1 (IGF-1) receptor and insulin/IGF-1 hybrid receptors.
G. Pandini, T. Wurch, B. Akla, N. Corvaia +2 more
2007European Journal of Cancer79 citations
Semantic Scholar
Insulin and Hybrid Insulin/IGF Receptors Are Major Regulators of Breast Cancer Cells
F. Frasca, G. Pandini, R. Vigneri, I. Goldfine
2003Breast Disease64 citations
Semantic Scholar
Overexpression of membrane glycoprotein PC-1 in MDA-MB231 breast cancer cells is associated with inhibition of insulin receptor tyrosine kinase activity.
A. Belfiore, A. Costantino, F. Frasca, G. Pandini +5 more
1996Molecular Endocrinology62 citations Open access
Semantic Scholar
Research resource: New and diverse substrates for the insulin receptor isoform A revealed by quantitative proteomics after stimulation with IGF-II or insulin.
A. Morcavallo, M. Gaspari, G. Pandini, A. Palummo +4 more
2011Molecular Endocrinology55 citations Open access
Semantic Scholar
Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type‐1 insulin‐like growth factor receptors in neuronal cells
S. Zimbone, I. Monaco, F. Gianì, G. Pandini +3 more
2017Aging Cell51 citations Open access
Semantic Scholar
Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons
M. L. Giuffrida, M. Tomasello, G. Pandini, F. Caraci +13 more
2015Frontiers in Cellular Neuroscience50 citations Open access
Semantic Scholar
IGF‐II Binding to Insulin Receptor Isoform A Induces a Partially Different Gene Expression Profile from Insulin Binding
G. Pandini, Enrico Conte, E. Medico, L. Sciacca +2 more
2004Annals of the New York Academy of Sciences47 citations
Semantic Scholar
Role of cyclic AMP response element-binding protein in insulin-like growth factor-i receptor up-regulation by sex steroids in prostate cancer cells.
M. Genua, G. Pandini, D. Sisci, G. Castoria +3 more
2009Cancer Research45 citations Open access
Semantic Scholar
Palmitate affects insulin receptor phosphorylation and intracellular insulin signal in a pancreatic alpha-cell line.
S. Piro, E. Maniscalchi, Adelina Monello, G. Pandini +3 more
2010Endocrinology43 citations Open access
Semantic Scholar
Interleukin-4 stimulates papillary thyroid cancer cell survival: implications in patients with thyroid cancer and concomitant Graves' disease.
V. Vella, R. Mineo, F. Frasca, E. Mazzon +3 more
2004Journal of Clinical Endocrinology and Metabolism42 citations Open access
Semantic Scholar
Reactivation of p53 mutants by p53 reactivation and induction of massive apoptosis in thyroid cancer cells
Rosa Linda Messina, Mariangela Sanfilippo, V. Vella, G. Pandini +5 more
201239 citations Open access
Semantic Scholar
HMGA1 protein is a positive regulator of the insulin-like growth factor-I receptor gene.
A. Aiello, G. Pandini, R. Sarfstein, H. Werner +3 more
2010European Journal of Cancer38 citations
Semantic Scholar
Role of c-Abl in Directing Metabolic versus Mitogenic Effects in Insulin Receptor Signaling*
F. Frasca, G. Pandini, R. Malaguarnera, A. Mandarino +4 more
2007Journal of Biological Chemistry37 citations Open access
Semantic Scholar
The Copper(II)-Assisted Connection between NGF and BDNF by Means of Nerve Growth Factor-Mimicking Short Peptides
Irina Naletova, C. Satriano, A. Pietropaolo, F. Gianì +9 more
2019Cells35 citations Open access
Semantic Scholar
17β-Estradiol Up-regulates the Insulin-like Growth Factor Receptor through a Nongenotropic Pathway in Prostate Cancer Cells
G. Pandini, M. Genua, F. Frasca, S. Squatrito +2 more
200735 citations
Semantic Scholar
The Inorganic Side of NGF: Copper(II) and Zinc(II) Affect the NGF Mimicking Signaling of the N-Terminus Peptides Encompassing the Recognition Domain of TrkA Receptor
G. Pandini, C. Satriano, A. Pietropaolo, F. Gianì +4 more
2016Frontiers in Neuroscience31 citations Open access
Semantic Scholar
Reactivation of p53 mutants by prima-1 [corrected] in thyroid cancer cells.
Rosa Linda Messina, Mariangela Sanfilippo, V. Vella, G. Pandini +5 more
2012International Journal of Cancer31 citations Open access
Semantic Scholar
Androgens Upregulate the Insulin-like Growth Factor-I Receptor in Prostate Cancer Cells
G. Pandini, R. Mineo, F. Frasca, C. Roberts +3 more
200531 citations
Semantic Scholar
c-Abl and insulin receptor signalling.
M. Genua, G. Pandini, M. Cassarino, Rosa Linda Messina +1 more
2009Vitamins and hormones28 citations
Semantic Scholar
Chromosome 15 structural abnormalities: effect on IGF1R gene expression and function
R. Cannarella, T. Mattina, R. Condorelli, L. Mongioì +3 more
2017Endocrine Connections27 citations Open access
Semantic Scholar
TAp73α Increases p53 Tumor Suppressor Activity in Thyroid Cancer Cells via the Inhibition of Mdm2-Mediated Degradation
R. Malaguarnera, V. Vella, G. Pandini, Mariangela Sanfilippo +3 more
2008Molecular Cancer Research22 citations Open access
Semantic Scholar
Effect of low-dose tungsten on human thyroid stem/precursor cells and their progeny.
F. Gianì, G. Pandini, N. Scalisi, P. Vigneri +7 more
2019Endocrine-Related Cancer19 citations Open access
Semantic Scholar
Sex Steroids Upregulate the IGF‐1R in Prostate Cancer Cells through a Nongenotropic Pathway
G. Pandini, M. Genua, F. Frasca, R. Vigneri +1 more
2009Annals of the New York Academy of Sciences19 citations
Semantic Scholar
Interleukin-1 blocks insulin and insulin-like growth factor-stimulated growth in MCF-7 human breast cancer cells by inhibiting receptor tyrosine kinase activity.
A. Costantino, C. Vinci, R. Mineo, F. Frasca +4 more
1996Endocrinology19 citations
Semantic Scholar
Identification of a novel EphB4 phosphodegron regulated by the autocrine IGFII/IRA axis in malignant mesothelioma
Pierluigi Scalia, G. Pandini, V. Carnevale, A. Giordano +1 more
2019Oncogene17 citations Open access
Semantic Scholar
Thyroid Stem Cells But Not Differentiated Thyrocytes Are Sensitive to Slightly Increased Concentrations of Heavy Metals
F. Gianì, Roberta Masto, M. Trovato, A. Franco +2 more
2021Frontiers in Endocrinology16 citations Open access
Semantic Scholar
17beta-estradiol up-regulates the insulin-like growth factor receptor through a nongenotropic pathway in prostate cancer cells.
G. Pandini, M. Genua, F. Frasca, S. Squatrito +2 more
2007Cancer Research15 citations
Semantic Scholar
Neurotrophin-mimicking peptides at the biointerface with gold respond to copper ion stimuli.
C. Satriano, Giuseppe Forte, A. Magrì, P. Di Pietro +4 more
2016Physical Chemistry, Chemical Physics - PCCP7 citations
Semantic Scholar
Effects of prophylaxis with iodised salt in an area of endemic goitre in north-eastern Sicily.
C. Regalbuto, G. Scollo, G. Pandini, R. Ferrigno +1 more
2010Journal of Endocrinological Investigation4 citations
Semantic Scholar
Effects of prophylaxis with iodised salt in an area of endemic goitre in north-eastern Sicily
Concetto Regalbuto, G. Scollo, G. Pandini, R. Ferrigno +1 more
20104 citations
Semantic Scholar

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R. Vigneri×36
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R. Vigneri — researcher profile on SciRah
A. Belfiore×30
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A. Belfiore — researcher profile on SciRah
F. Frasca×23
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L. Sciacca×13
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R. Mineo — researcher profile on SciRah

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F. Gianì — researcher profile on SciRah

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S. Squatrito — researcher profile on SciRah

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M. Genua — researcher profile on SciRah

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