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M. Bickle · SciRah

Researcher profile · Semantic Scholar

M. Bickle

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M. Bickle — researcher profile on SciRah

h-index: 28
Works: 76
Citations: 6,544

Most-cited papers

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape
J. Gilleron, W. Querbes, Anja Zeigerer, A. Borodovsky +16 more
2013Nature Biotechnology1,549 citations
Semantic Scholar
RNA buffers the phase separation behavior of prion-like RNA-binding proteins
Shovamayee Maharana, Jie Wang, D. Papadopoulos, Doris Richter +13 more
2018Science1,028 citations Open access
Semantic Scholar
Multilineage communication regulates human liver bud development from pluripotency
J. Camp, K. Sekine, Tobias Gerber, H. Loeffler-Wirth +16 more
2017Nature588 citations
Semantic Scholar
Screening out irrelevant cell-based models of disease
P. Horváth, Nathalie Aulner, M. Bickle, A. Davies +10 more
2016Nature reviews. Drug discovery497 citations Open access
Semantic Scholar
The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2.
A. Schmidt, M. Bickle, T. Beck, M. Hall
1997Cell329 citations Open access
Semantic Scholar
3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions.
Carsten Wenzel, B. Riefke, S. Gründemann, Alice Krebs +14 more
2016Experimental Cell Research233 citations Open access
Semantic Scholar
Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale
Prasath Paramasivam, Christian Franke, M. Stöter, Andreas Höijer +10 more
2020bioRxiv209 citations Open access
Semantic Scholar
Cell wall integrity modulates RHO1 activity via the exchange factor ROM2
M. Bickle, P. Delley, A. Schmidt, Michael N. Hall
1998EMBO Journal198 citations Open access
Semantic Scholar
The beautiful cell: high-content screening in drug discovery
M. Bickle
2010Analytical and Bioanalytical Chemistry180 citations
Semantic Scholar
Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour
A. Ettinger, Michaela Wilsch-Bräuninger, A. Marzesco, M. Bickle +6 more
2011Nature Communications164 citations Open access
Semantic Scholar
A Conserved RhoGAP Limits M-phase Contractility and Coordinates with Microtubule Asters to Restrict Active RhoA to the Cell Equator During Cytokinesis
E. Zanin, A. Desai, I. Poser, Y. Toyoda +6 more
2013Developmental Cell98 citations Open access
Semantic Scholar
Gender, Contraceptives and Individual Metabolic Predisposition Shape a Healthy Plasma Lipidome
Susanne Sales, J. Graessler, S. Ciucci, Rania Al-Atrib +9 more
2016Scientific Reports97 citations Open access
Semantic Scholar
Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy
Lara Marrone, I. Poser, Ian Casci, Julia Japtok +17 more
2018Stem Cell Reports96 citations Open access
Semantic Scholar
Integration of chemical and RNAi multiparametric profiles identifies triggers of intracellular mycobacterial killing.
Varadharajan Sundaramurthy, R. Barsacchi, N. Samusik, Giovanni Marsico +6 more
2013Cell Host and Microbe91 citations Open access
Semantic Scholar
Concerns, challenges and promises of high-content analysis of 3D cellular models
N. Carragher, F. Piccinini, A. Tesei, O. J. Trask +2 more
2018Nature reviews. Drug discovery86 citations Open access
Semantic Scholar
Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model
Danielle J. Borg, Marc Weigelt, Carmen Wilhelm, Michael Gerlach +4 more
2014Diabetologia83 citations
Semantic Scholar
Small molecule modulation of a redox-sensitive stress granule protein dissolves stress granules with beneficial outcomes for familial amyotrophic lateral sclerosis models
R. Wheeler, Hyun O. Lee, I. Poser, A. Pal +20 more
2019bioRxiv78 citations Open access
Semantic Scholar
Age-Dependent Labeling and Imaging of Insulin Secretory Granules
A. Ivanova, Y. Kalaidzidis, R. Dirkx, M. Sarov +12 more
2013Diabetes71 citations Open access
Semantic Scholar
Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins
Masin Abo-Rady, N. Kalmbach, A. Pal, Carina Schludi +15 more
2020Stem Cell Reports61 citations Open access
Semantic Scholar
Protective efficacy of phosphodiesterase-1 inhibition against alpha-synuclein toxicity revealed by compound screening in LUHMES cells
M. Höllerhage, Claudia Moebius, Johannes Melms, W. Chiu +7 more
2017Scientific Reports61 citations Open access
Semantic Scholar
Identification of siRNA delivery enhancers by a chemical library screen
J. Gilleron, Prasath Paramasivam, Anja Zeigerer, W. Querbes +14 more
2015Nucleic Acids Research61 citations Open access
Semantic Scholar
Selection and characterization of large collections of peptide aptamers through optimized yeast two-hybrid procedures
M. Bickle, E. Dusserre, O. Moncorgé, Hélène Bottin +1 more
2006Nature Protocols59 citations
Semantic Scholar
High Diversity in the TCR Repertoire of GAD65 Autoantigen-Specific Human CD4+ T Cells
A. Eugster, Annett Lindner, M. Catani, Anne-Kristin Heninger +7 more
2015Journal of Immunology58 citations Open access
Semantic Scholar
Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo
L. Reinhardt, Susanne Kordes, Peter Reinhardt, Michael Glatza +22 more
2019Stem Cell Reports46 citations Open access
Semantic Scholar
CellProfiler and KNIME: open source tools for high content screening.
M. Stöter, A. Niederlein, R. Barsacchi, Felix Meyenhofer +2 more
2013Methods in molecular biology43 citations
Semantic Scholar
Simulation of amoxicillin pharmacokinetics in humans for the prevention of streptococcal endocarditis in rats
U. Flúckiger, P. Moreillon, J. Blaser, M. Bickle +2 more
1994Antimicrobial Agents and Chemotherapy35 citations Open access
Semantic Scholar
Peptide aptamers for small molecule drug discovery.
Carine Bardou, Christophe Borie, M. Bickle, B. Rudkin +1 more
2009Methods in molecular biology32 citations
Semantic Scholar
Loss of a gluconeogenic muscle enzyme contributed to adaptive metabolic traits in hummingbirds
E. Osipova, R. Barsacchi, Tom Brown, K. Sadanandan +10 more
2023Science31 citations
Semantic Scholar
Live-Cell High Content Screening in Drug Development.
M. Esner, Felix Meyenhofer, M. Bickle
2018Methods in molecular biology26 citations
Semantic Scholar
Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen
Varadharajan Sundaramurthy, R. Barsacchi, M. Chernykh, M. Stöter +4 more
2014Nature Protocols23 citations
Semantic Scholar
A Comparative Analysis of Perturbations Caused by a Gene Knock-out, a Dominant Negative Allele, and a Set of Peptide Aptamers*S
N. Abed, M. Bickle, B. Mari, M. Schapira +9 more
2007Molecular & Cellular Proteomics23 citations Open access
Semantic Scholar
A high-throughput siRNA screen identifies genes that regulate mannose 6-phosphate receptor trafficking
Mihaela Anitei, R. Chenna, C. Czupalla, M. Esner +7 more
2014Journal of Cell Science21 citations Open access
Semantic Scholar
An Antiproliferative Genetic Screening Identifies a Peptide Aptamer That Targets Calcineurin and Up-regulates Its Activity*
B. de Chassey, I. Mikaelian, Anne-Laure Mathieu, M. Bickle +5 more
2007Molecular & Cellular Proteomics21 citations Open access
Semantic Scholar
A RasGAP SH3 Peptide Aptamer Inhibits RasGAP-Aurora Interaction and Induces Caspase-Independent Tumor Cell Death
P. Pamonsinlapatham, Réda Hadj-Slimane, Françoise Raynaud, M. Bickle +13 more
2008PLoS ONE19 citations Open access
Semantic Scholar
High-content screening: a new primary screening tool?
M. Bickle
2008IDrugs. The Investigational Drugs Journal18 citations
Semantic Scholar
Image analysis in high-content screening.
A. Niederlein, Felix Meyenhofer, Daniel White, M. Bickle
2009Combinatorial chemistry & high throughput screening17 citations
Semantic Scholar
Inhibition of vaccinia virus replication by peptide aptamers.
L. Saccucci, J. Crance, P. Colas, M. Bickle +2 more
2009Antiviral Research17 citations
Semantic Scholar
Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy.
Shrestha Sinha Ray, Debdeep Dutta, Cassandra N. Dennys, Samantha Powers +13 more
2022Cell Reports15 citations Open access
Semantic Scholar
Characterization of peptide aptamers targeting Bfl-1 anti-apoptotic protein.
G. Brien, Anne-Laure Debaud, M. Bickle, M. Trescol-Biémont +3 more
2011Biochemistry15 citations
Semantic Scholar
In Vivo Chemical Screen in Zebrafish Embryos Identifies Regulators of Hematopoiesis Using a Semiautomated Imaging Assay
Guruchandar Arulmozhivarman, M. Stöter, M. Bickle, M. Kräter +6 more
2016Journal of biomolecular screening14 citations Open access
Semantic Scholar
Image Analysis in High Content Screening
A. Niederlein, Felix Meyenhofer, Daniel White, M. Bickle
200914 citations
Semantic Scholar
Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation
J. Carthy, M. Stöter, C. Bellomo, M. Vanlandewijck +9 more
2016Scientific Reports12 citations Open access
Semantic Scholar
High Content Screening in Drug Discovery
M. Bickle
201012 citations
Semantic Scholar
A Human Retinal Pigment Epithelium-Based Screening Platform Reveals Inducers of Photoreceptor Outer Segments Phagocytosis
Sven Schreiter, K. Vafia, R. Barsacchi, Stephen H. Tsang +5 more
2020Stem Cell Reports11 citations Open access
Semantic Scholar
Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs
E. Kemter, Andreas Müller, Martin Neukam, A. Ivanova +15 more
2021Proceedings of the National Academy of Sciences of the United States of America10 citations Open access
Semantic Scholar
Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery
S. Poser, O. Otto, Carina Arps-Forker, Yan Ge +21 more
2019The FASEB Journal10 citations Open access
Semantic Scholar
CellProfiler and KNIME: Open-Source Tools for High-Content Screening.
M. Stöter, Antje Janosch, R. Barsacchi, M. Bickle
2019Methods in molecular biology10 citations
Semantic Scholar
Layer-by-Layer Assembly of Heparin and Peptide-Polyethylene Glycol Conjugates to Form Hybrid Nanothin Films of Biomatrices.
A. K. Thomas, Robert Wieduwild, R. Zimmermann, Weilin Lin +5 more
2018ACS Applied Materials and Interfaces10 citations Open access
Semantic Scholar
Zebrafish In-Vivo Screening for Compounds Amplifying Hematopoietic Stem and Progenitor Cells: - Preclinical Validation in Human CD34+ Stem and Progenitor Cells
Guruchandar Arulmozhivarman, Martin Kräter, M. Wobus, J. Friedrichs +13 more
2017Scientific Reports10 citations Open access
Semantic Scholar
Viral Infections Exacerbate FUS-ALS Phenotypes in iPSC-Derived Spinal Neurons in a Virus Species-Specific Manner
J. Bellmann, A. Monette, Vadreenath Tripathy, Anna Sojka +6 more
2019Frontiers in Cellular Neuroscience9 citations Open access
Semantic Scholar

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