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M. Dockendorf · SciRah

Researcher profile · Semantic Scholar

M. Dockendorf

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M. Dockendorf — researcher profile on SciRah

h-index: 18
Works: 46
Citations: 1,200

Most-cited papers

The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer’s disease patients
M. Kennedy, A. Stamford, Xia Chen, K. Cox +20 more
2016Science Translational Medicine386 citations
Semantic Scholar
Safety, Tolerability and Pharmacokinetics of Doravirine, a Novel HIV Non-Nucleoside Reverse Transcriptase Inhibitor, after Single and Multiple doses in Healthy Subjects
Matt S. Anderson, Jocelyn Gilmartin, C. Cilissen, I. de Lepeleire +8 more
2015Antiviral Therapy76 citations Open access
Semantic Scholar
Pharmacokinetics and Safety of Caspofungin in Older Infants and Toddlers
M. Neely, H. Jafri, N. Seibel, K. Knapp +8 more
2008Antimicrobial Agents and Chemotherapy71 citations Open access
Semantic Scholar
Digitally Enabled, Patient‐Centric Clinical Trials: Shifting the Drug Development Paradigm
M. Dockendorf, Bryan J Hansen, K. Bateman, Matthew Moyer +2 more
2020Clinical and Translational Science55 citations Open access
Semantic Scholar
An Integrated Strategy for Implementation of Dried Blood Spots in Clinical Development Programs
P. Kothare, K. Bateman, M. Dockendorf, J. Stone +3 more
2016AAPS Journal51 citations Open access
Semantic Scholar
Precompetitive Consensus Building to Facilitate the Use of Digital Health Technologies to Support Parkinson Disease Drug Development through Regulatory Science
D. Stephenson, R. Alexander, Varun Aggarwal, Reham Badawy +38 more
2020Digital Biomarkers49 citations Open access
Semantic Scholar
Population PK Analyses of Ubrogepant (MK‐1602), a CGRP Receptor Antagonist: Enriching In‐Clinic Plasma PK Sampling With Outpatient Dried Blood Spot Sampling
Chi-Chung Li, M. Dockendorf, K. Kowalski, Bei Yang +10 more
2018Journal of clinical pharmacology41 citations
Semantic Scholar
Oral Sessions: O1-06: Therapeutics: Clinical Trials I P139 O1-06-04 EFFICACY OF SOLANEZUMAB IN PATIENTS WITH MILD OR MODERATE ALZHEIMER’S DISEASE: POOLED ANALYSES FINDINGS FROM TWO PHASE III STUDIES
Joel Raskin, H. Kleijn, M. Dockendorf, J. Palcza +25 more
201341 citations
Semantic Scholar
Atogepant Has No Clinically Relevant Effects on the Pharmacokinetics of an Ethinyl Estradiol/Levonorgestrel Oral Contraceptive in Healthy Female Participants
Wendy Ankrom, Jialin Xu, Marie-Helene Vallee, M. Dockendorf +3 more
2020Journal of clinical pharmacology39 citations Open access
Semantic Scholar
Human-Centered Design Strategies for Device Selection in mHealth Programs: Development of a Novel Framework and Case Study
A. Polhemus, J. Novák, José Ferrão, S. Simblett +17 more
2020JMIR mHealth and uHealth38 citations Open access
Semantic Scholar
Population Pharmacokinetics and Pharmacodynamics of Caspofungin in Pediatric Patients
Chi-Chung Li, Peng Sun, Ying-Wen Dong, S. Bi +6 more
2011Antimicrobial Agents and Chemotherapy38 citations Open access
Semantic Scholar
Data Visualization for Chronic Neurological and Mental Health Condition Self-management: Systematic Review of User Perspectives
A. Polhemus, J. Novák, Shazmin Majid, S. Simblett +6 more
2022JMIR Mental Health37 citations Open access
Semantic Scholar
Atogepant Is Not Associated With Clinically Meaningful Alanine Aminotransferase Elevations in Healthy Adults
K. Min, W. Kraft, Bondiskey Phung, Francheska M. Colón-González +7 more
2020Clinical and Translational Science29 citations Open access
Semantic Scholar
Facial and Vocal Markers of Schizophrenia Measured Using Remote Smartphone Assessments: Observational Study
Anzar Abbas, Bryan J. Hansen, Vidya Koesmahargyo, V. Yadav +7 more
2020JMIR Formative Research28 citations Open access
Semantic Scholar
Model-Based Development of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor
R. Krishna, A. Bergman, Michèle Green, M. Dockendorf +2 more
2011AAPS Journal25 citations Open access
Semantic Scholar
Pharmacokinetics and Pharmacodynamics of the BACE1 Inhibitor Verubecestat (MK‐8931) in Healthy Japanese Adults: A Randomized, Placebo‐Controlled Study
K. Min, M. Dockendorf, J. Palcza, J. Tseng +9 more
2019Clinical pharmacology and therapy22 citations
Semantic Scholar
Ubrogepant Is Not Associated With Clinically Meaningful Elevations of Alanine Aminotransferase in Healthy Adult Males
Wendy Ankrom, Bondiskey Phung, Chi-Chung Li, J. Palcza +10 more
2020Clinical and Translational Science20 citations Open access
Semantic Scholar
Leveraging Digital Health Technologies and Outpatient Sampling in Clinical Drug Development: A Phase I Exploratory Study
M. Dockendorf, G. Murthy, K. Bateman, P. Kothare +10 more
2018Clinical pharmacology and therapy20 citations Open access
Semantic Scholar
Accelerating Parkinson’s Disease drug development with federated learning approaches
Amit Khanna, Jamie L. Adams, C. Antoniades, B. Bloem +31 more
2024npj Parkinson's Disease18 citations Open access
Semantic Scholar
Facial and vocal markers of schizophrenia measured using remote smartphone assessments
I. Galatzer-Levy, A. Abbas, Vidya Koesmahargyo, V. Yadav +7 more
2020medRxiv16 citations Open access
Semantic Scholar
Safety, Tolerability, and Pharmacokinetics of the β‐Site Amyloid Precursor Protein‐Cleaving Enzyme 1 Inhibitor Verubecestat (MK‐8931) in Healthy Elderly Male and Female Subjects
M. Forman, J. Palcza, J. Tseng, J. Stone +4 more
2019Clinical and Translational Science16 citations Open access
Semantic Scholar
Experiences of health tracking in mobile apps for multiple sclerosis: A qualitative content analysis of user reviews.
A. Polhemus, S. Simblett, Erin Dawe Lane, Benjamin Elliott +8 more
2022Multiple Sclerosis and Related Disorders8 citations Open access
Semantic Scholar
Pharmacokinetics of vorapaxar and its metabolite following oral administration in healthy Chinese and American subjects.
Xia Chen, T. Kosoglou, P. Statkevich, B. Kumar +9 more
2014International journal of clinical pharmacology and therapeutics8 citations
Semantic Scholar
Pharmacokinetics, safety and tolerability of long‐acting parenteral intramuscular injection formulations of doravirine
Ka L. Yee, S. Mittal, L. Fan, Ilias Triantafyllou +5 more
2020Journal of Clinical Pharmacy and Therapeutics7 citations Open access
Semantic Scholar
P1‐221: Safety and pharmacokinetics of the novel BACE inhibitor MK‐8931 in healthy subjects following single‐ and Multiple‐Dose administration
J. Tseng, M. Dockendorf, G. Krishna, Lei Ma +9 more
20127 citations
Semantic Scholar
P4‐196: The novel BACE inhibitor MK‐8931 dramatically lowers cerebrospinal fluid Aβ peptides in healthy subjects following single‐ and multiple‐dose administration
Mark A. Forman, J. Palcza, J. Tseng, Jos Leempoels +11 more
20127 citations
Semantic Scholar
Pharmacokinetic and pharmacodynamic assessments of atogepant in healthy male adults: Results from phase 1 studies
R. Boinpally, M. Depre, G. Van Lancker, M. Dockendorf +8 more
2023Cephalalgia Reports6 citations Open access
Semantic Scholar
Effects of CYP3A4 and P-glycoprotein inhibition or induction on the pharmacokinetics of ubrogepant in healthy adults: Two phase 1, open-label, fixed-sequence, single-center, crossover trials
Abhijeet S. Jakate, R. Boinpally, M. Butler, Wendy Ankrom +2 more
2021Cephalalgia Reports6 citations Open access
Semantic Scholar
A Model-Based Approach to Bridging Plasma and Dried Blood Spot Concentration Data for Phase 3 Verubecestat Trials
M. Dockendorf, D. Jaworowicz, Rebecca L. Humphrey, M. Anderson +11 more
2022AAPS Journal5 citations
Semantic Scholar
Leveraging model-informed approaches for drug discovery and development in the cardiovascular space
M. Dockendorf, R. Vargo, F. Gheyas, A. Chain +2 more
2018Journal of Pharmacokinetics and Pharmacodynamics5 citations Open access
Semantic Scholar
P1‐334: Development and application of a mathematical model of modulation of cerebrospinal fluid Aβ40 after treatment with gamma‐ and beta‐secretase inhibitors
H. Kleijn, Lei Ma, M. Dockendorf, R. de Greef +4 more
20125 citations Open access
Semantic Scholar
A novel machine learning based framework for developing composite digital biomarkers of disease progression
Song Zhai, Andy Liaw, Ju-Dong Shen, Yuting Xu +7 more
2024medRxiv4 citations Open access
Semantic Scholar
An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat
M. Anderson, M. Dockendorf, Ian Mcintosh, Iris H. Xie +9 more
2022AAPS Journal4 citations
Semantic Scholar
P1‐225: A study to evaluate the pharmacokinetics and pharmacodynamics of single and multiple oral doses of the novel BACE inhibitor MK‐8931 in Japanese subjects
K. Min, M. Forman, M. Dockendorf, J. Palcza +8 more
20124 citations Open access
Semantic Scholar
Data visualization in chronic neurological and mental health condition self-management: a systematic review of user perspectives (Preprint)
A. Polhemus, J. Novák, Shazmin Majid, S. Simblett +5 more
20202 citations Open access
Semantic Scholar
Multiple, Once-Daily, Oral Doses of 150 mg Ubrogepant Administered for 28 Days Are Generally Well Tolerated, With No Clinically Significant Elevation of Alanine Aminotransferase in Healthy Adult Males (P2.10-024)
Wendy Ankrom, Bondiskey Phung, Wen Liu, J. Palcza +7 more
2019Neurology2 citations
Semantic Scholar
Digital endpoints in clinical trials: building the business case for systematic adoption.
Jennifer C. Goldsack, Sarah Ernst, M. Dockendorf, T. Perumal +1 more
2026Nature reviews. Drug discovery1 citations Open access
Semantic Scholar
P2‐002: AN INTEGRATED MECHANISTIC AMYLOID PATHWAY MODEL INFORMED BY CLINICAL BIOMARKER DATA FROM VERUBECESTAT AND OTHER BACE INHIBITORS
C. Rasmussen, H. Kleijn, J. Kalinina, M. Dockendorf +4 more
2019Alzheimer's & Dementia1 citations
Semantic Scholar
Human-Centered Design Strategies for Device Selection in mHealth Programs: Development of a Novel Framework and Case Study (Preprint)
A. Polhemus, J. Novák, José Ferrão, S. Simblett +17 more
20191 citations Open access
Semantic Scholar
5th Conference Clinical Trials on Alzheimer’s Disease
F. M, Egan, M. Forman, J. Palcza +20 more
2012The Journal of Nutrition, Health & Aging1 citations Open access
Semantic Scholar
Absence of Clinically Significant Drug Interactions With Coadministration of Atogepant and an Ethinyl Estradiol/Levonorgestrel Oral Contraceptive in Healthy Female Subjects: A Phase 1 Pharmacokinetic Analysis (P1.10-019)
Wendy Ankrom, Jialin Xu, Marie-Helene Vallee, M. Dockendorf +3 more
2019Neurology0 citations
Semantic Scholar
P3-040: VERUBECESTAT PHARMACOKINETIC AND EXPOSURE-RESPONSE RESULTS FROM APECS, A PHASE 3 TRIAL IN PRODROMAL ALZHEIMER'S DISEASE
J. Stone, H. Kleijn, D. Jaworowicz, J. Passarell +6 more
2019Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Mathematical modeling of left ventricle hypertrophy and dilatation in response to volume overload in heart failure: a coupled renal‐cardiac model
Sommer Anjum, Guido H. Jajamovich, Richard J. Allen, Anna Sher +3 more
20180 citations
Semantic Scholar
P1‐038: VERUBECESTAT PHARMACOKINETIC AND EXPOSURE‐RESPONSE RESULTS FROM EPOCH: A PHASE 3 TRIAL IN MILD‐TO‐MODERATE ALZHEIMER'S DISEASE
Julie A. Stone, H. Kleijn, David J. Jaworowicz, M. Dockendorf +5 more
20180 citations
Semantic Scholar
Population Modeling Is a Critical Element of Bridging Pharmacokinetic Data From Dried Blood Spot and Plasma Across Clinical Programs
M. Dockendorf, K. Kowalski, B. Yang, L. Ma +10 more
20140 citations
Semantic Scholar
P1‐229: Population pharmacokinetic modeling of the novel BACE inhibitor MK‐8931 following single and multiple dose administration in healthy subjects
Lei Ma, M. Dockendorf, Gopal Krishna, H. Kleijn +3 more
20120 citations
Semantic Scholar

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