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S. Plymate · SciRah

Researcher profile · Semantic Scholar

S. Plymate

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S. Plymate — researcher profile on SciRah

h-index: 69
Works: 261
Citations: 23K

Most-cited papers

Integrative clinical genomics of advanced prostate cancer
D. Robinson, E. V. Van Allen, Yi-Mi Wu, N. Schultz +69 more
2015Cell3,286 citations Open access
Semantic Scholar
Integrative Clinical Genomics of Advanced Prostate Cancer.
D. Robinson, E. V. Van Allen, Yi-Mi Wu, N. Schultz +69 more
2015Cell446 citations Open access
Semantic Scholar
Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer
A. Sharp, I. Coleman, W. Yuan, Cynthia Sprenger +18 more
2018Journal of Clinical Investigation341 citations Open access
Semantic Scholar
Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer
G. Zadra, C. Ribeiro, P. Chetta, Yeung Ho +28 more
2018Proceedings of the National Academy of Sciences of the United States of America276 citations Open access
Semantic Scholar
Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling
L. Brady, M. Kriner, I. Coleman, C. Morrissey +11 more
2021Nature Communications209 citations Open access
Semantic Scholar
Alternative splicing in prostate cancer
A. Paschalis, A. Sharp, J. Welti, A. Neeb +4 more
2018Nature Reviews Clinical Oncology167 citations
Semantic Scholar
Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer
C. Henzler, Ying-Ming Li, Ren-Dong Yang, T. McBride +16 more
2016Nature Communications159 citations Open access
Semantic Scholar
ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
Laura Cato, Jonas de Tribolet-Hardy, Irene Lee, Jaice T. Rottenberg +31 more
2019Cancer Cell151 citations Open access
Semantic Scholar
BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer
Irfan A. Asangani, K. Wilder-Romans, Vijaya L. Dommeti, P. M. Krishnamurthy +7 more
2016Molecular Cancer Research151 citations Open access
Semantic Scholar
Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC)
J. Welti, A. Sharp, W. Yuan, D. Dolling +22 more
2018Clinical Cancer Research131 citations
Semantic Scholar
A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer
M. Schweizer, K. Haugk, Jožefa S. McKiernan, R. Gulati +8 more
2018PLoS ONE131 citations Open access
Semantic Scholar
Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting
Jun Luo, G. Attard, S. Balk, C. Bevan +23 more
2017European Urology124 citations Open access
Semantic Scholar
Neoadjuvant Enzalutamide Prior to Prostatectomy
B. Montgomery, M. Tretiakova, A. Joshua, M. Gleave +20 more
2016Clinical Cancer Research123 citations Open access
Semantic Scholar
Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer
Shan Wang, R. Kollipara, N. Srivastava, Rui Li +12 more
2014Proceedings of the National Academy of Sciences of the United States of America123 citations Open access
Semantic Scholar
Intense Exercise for Survival among Men with Metastatic Castrate-Resistant Prostate Cancer (INTERVAL-GAP4): a multicentre, randomised, controlled phase III study protocol
R. Newton, S. Kenfield, N. Hart, J. Chan +17 more
2018BMJ Open120 citations Open access
Semantic Scholar
Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer
J. Welti, D. Rodrigues, A. Sharp, Shi-Hua Sun +7 more
2016European Urology117 citations Open access
Semantic Scholar
Novel androgen receptor co-regulator GRHL2 exerts both oncogenic and anti-metastatic functions in prostate cancer
S. Paltoglou, R. Das, S. Townley, Theresa E. Hickey +11 more
2017Cancer Research98 citations Open access
Semantic Scholar
Targeting androgen receptor activation function-1 with EPI to overcome resistance mechanisms in castration-resistant prostate cancer
Yu-Chi Yang, C. A. Banuelos, N. Mawji, Jun Wang +5 more
2016Clinical Cancer Research96 citations Open access
Semantic Scholar
The link between androgen receptor splice variants and castration resistant prostate cancer
Cynthia C. T. Sprenger, S. Plymate
2014Hormones & cancer78 citations Open access
Semantic Scholar
Clinical Utility of Circulating Tumour Cell Androgen Receptor Splice Variant-7 Status in Metastatic Castration-resistant Prostate Cancer.
A. Sharp, J. Welti, M. Lambros, D. Dolling +31 more
2019European Urology72 citations Open access
Semantic Scholar
A phase I dose-escalation study of enzalutamide in combination with the AKT inhibitor AZD5363 (capivasertib) in patients with metastatic castration-resistant prostate cancer
M. Kolinsky, P. Rescigno, D. Bianchini, Z. Zafeiriou +26 more
2020Annals of Oncology68 citations Open access
Semantic Scholar
Small Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer
Kimberly McClinch, Rita A. Avelar, David Callejas, S. Izadmehr +26 more
2018Cancer Research68 citations Open access
Semantic Scholar
Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer
Ying-Ming Li, Ren-Dong Yang, C. Henzler, Yeung Ho +15 more
2020Clinical Cancer Research67 citations Open access
Semantic Scholar
Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer
T. Uo, Cynthia C. T. Sprenger, S. Plymate
2020Frontiers in Oncology66 citations Open access
Semantic Scholar
The androgen receptor regulates a druggable translational regulon in advanced prostate cancer
Yuzhen Liu, Jessie L. Horn, Kalyan Banda, Asha Z. Goodman +20 more
2019Science Translational Medicine65 citations Open access
Semantic Scholar
Novel Junction-specific and Quantifiable In Situ Detection of AR-V7 and its Clinical Correlates in Metastatic Castration-resistant Prostate Cancer
Yezi Zhu, A. Sharp, Courtney M. Anderson, J. Silberstein +20 more
2017European Urology56 citations Open access
Semantic Scholar
SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer.
Evan Y. Yu, Hongli Li, C. Higano, N. Agarwal +15 more
2015Journal of Clinical Oncology52 citations Open access
Semantic Scholar
Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs
Dong Han, M. Labaf, Yawei Zhao, Jude Owiredu +26 more
2024Journal of Clinical Investigation43 citations Open access
Semantic Scholar
Differential Effects of Meal Challenges on Cognition, Metabolism, and Biomarkers for Apolipoprotein E ɛ4 Carriers and Adults with Mild Cognitive Impairment.
A. Hanson, J. Bayer, L. Baker, B. Cholerton +7 more
2015Journal of Alzheimer's Disease41 citations
Semantic Scholar
The potential of AR-V7 as a therapeutic target
T. Uo, S. Plymate, Cynthia C. T. Sprenger
2018Expert opinion on therapeutic targets38 citations
Semantic Scholar
Classical and non-classical roles for pre-receptor control of DHT metabolism in prostate cancer progression
Ai-Lin Zhang, Jia-Wei Zhang, S. Plymate, E. Mostaghel
2016Hormones & cancer38 citations Open access
Semantic Scholar
Supraphysiologic Testosterone Therapy in the Treatment of Prostate Cancer: Models, Mechanisms and Questions
O. .. Mohammad, Michael D Nyquist, M. Schweizer, S. Balk +4 more
2017Cancers36 citations Open access
Semantic Scholar
MED1 mediates androgen receptor splice variant induced gene expression in the absence of ligand
Gang Liu, Cynthia C. T. Sprenger, Pin-Jou Wu, Shi-Hua Sun +4 more
2014OncoTarget33 citations Open access
Semantic Scholar
JMJD6 is a druggable oxygenase that regulates AR-V7 expression in prostate cancer
A. Paschalis, J. Welti, A. Neeb, W. Yuan +29 more
2021Cancer Research32 citations Open access
Semantic Scholar
Assessment of Androgen Receptor splice variant-7 as a biomarker of clinical response in castration-sensitive prostate cancer
A. Sowalsky, I. Figueiredo, R. Lis, I. Coleman +27 more
2022medRxiv29 citations Open access
Semantic Scholar
Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth.
Michael D Nyquist, Lisa S. Ang, Alexandra Corella, I. Coleman +17 more
2021Journal of Clinical Investigation26 citations Open access
Semantic Scholar
Molecular determinants of response to high dose androgen therapy in prostate cancer.
Michael D Nyquist, Alexandra Corella, O. Mohamad, I. Coleman +7 more
2019JCI Insight26 citations Open access
Semantic Scholar
Correction: A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer
M. Schweizer, K. Haugk, Jožefa S. McKiernan, R. Gulati +8 more
2018PLoS ONE22 citations Open access
Semantic Scholar
Taxane resistance in prostate cancer mediated by AR-independent GATA2 regulation of IGF2.
S. Plymate, R. Bhatt, S. Balk
2015Cancer Cell19 citations Open access
Semantic Scholar
Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer
Irfan A. Asangani, I. Blair, G. Van Duyne, V. Hilser +5 more
2020Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Randomized Trial Evaluating the Role of Weight Loss in Overweight and Obese Men with Early Stage Prostate Cancer on Active Surveillance: Rationale and Design of the Prostate Cancer Active Lifestyle Study (PALS)
J. Schenk, M. Neuhouser, Sarah J. Beatty, M. VanDoren +6 more
2019Contemporary Clinical Trials16 citations Open access
Semantic Scholar
Druggable Metabolic Vulnerabilities Are Exposed and Masked during Progression to Castration Resistant Prostate Cancer
S. Choi, C. Ribeiro, Yu-Zhuo Wang, M. Loda +2 more
2022Biomolecules15 citations Open access
Semantic Scholar
Anti-Tumor Activity of the IGF-1/IGF-2-Neutralizing Antibody Xentuzumab (BI 836845) in Combination with Enzalutamide in Prostate Cancer Models
Ulrike Weyer-Czernilofsky, M. H. Hofmann, K. Friedbichler, Rosa Baumgartinger +9 more
2020Molecular Cancer Therapeutics15 citations Open access
Semantic Scholar
The androgen receptor mediates antiapoptotic function in myometrial cells
H. Li, Y. Li, D. Morin, S. Plymate +2 more
2014Cell Death and Disease15 citations Open access
Semantic Scholar
Nuclear Circulating Tumor Cell Androgen Receptor Variant 7 in Castration-Resistant Prostate Cancer: The Devil Is in the Detail.
S. Plymate, A. Sharp, J. de Bono
2018JAMA Oncology14 citations
Semantic Scholar
Metformin Effects on Biochemical Recurrence and Metabolic Signaling in the Prostate
B. Winters, S. Plymate, S. Zeliadt, S. Holt +8 more
2015The Prostate12 citations Open access
Semantic Scholar
Allosteric Alterations in the Androgen Receptor and Activity in Prostate Cancer
T. Uo, S. Plymate, Cynthia C. T. Sprenger
2017Endocrine-Related Cancer11 citations Open access
Semantic Scholar
UDP-glucuronosyltransferase Enzymes in Prostate Cancer Progression: Is Only Androgen Catabolism Involved?
E. Mostaghel, Ai-Lin Zhang, S. Plymate
2016European Urology11 citations Open access
Semantic Scholar
Intense exercise for survival among men with metastatic castrate-resistant prostate cancer (INTERVAL – MCRPC): A Movember funded multicenter, randomized, controlled phase III study.
F. Saad, S. Kenfield, J. Chan, N. Hart +16 more
201611 citations Open access
Semantic Scholar
Supraphysiological Androgens Promote the Tumor Suppressive Activity of the Androgen Receptor through cMYC Repression and Recruitment of the DREAM Complex
Michael D Nyquist, I. Coleman, Jared M. Lucas, Da-Pei Li +7 more
2023Cancer Research10 citations Open access
Semantic Scholar

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