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Harumi Kawaki · SciRah

Researcher profile · Semantic Scholar

Harumi Kawaki

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Harumi Kawaki — researcher profile on SciRah

h-index: 22
Works: 74
Citations: 1,267

Most-cited papers

Cooperative Regulation of Chondrocyte Differentiation by CCN2 and CCN3 Shown by a Comprehensive Analysis of the CCN Family Proteins in Cartilage
Harumi Kawaki, S. Kubota, Akiko Suzuki, N. Lazar +7 more
2008Journal of Bone and Mineral Research115 citations Open access
Semantic Scholar
CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes
Takashi Nishida, Harumi Kawaki, Ruth M. Baxter, R. Deyoung +2 more
2007Journal of cell communication and signaling91 citations Open access
Semantic Scholar
Regulation of chondrocytic phenotype by micro RNA 18a: Involvement of Ccn2/Ctgf as a major target gene
T. Ohgawara, S. Kubota, Harumi Kawaki, S. Kondo +5 more
2009FEBS Letters82 citations
Semantic Scholar
Differential roles of CCN family proteins during osteoblast differentiation: Involvement of Smad and MAPK signaling pathways.
Harumi Kawaki, S. Kubota, Akiko Suzuki, Makoto Suzuki +9 more
2011Bone79 citations
Semantic Scholar
Suppressive effect of overexpressed connective tissue growth factor on tumor cell growth in a human oral squamous cell carcinoma-derived cell line.
Norifumi H. Moritani, S. Kubota, Takashi Nishida, Harumi Kawaki +3 more
2003Cancer Letters61 citations
Semantic Scholar
Functional requirement of CCN2 for intramembranous bone formation in embryonic mice.
Harumi Kawaki, S. Kubota, Akiko Suzuki, Tomohiro Yamada +6 more
2008Biochemical and Biophysical Research Communications - BBRC52 citations Open access
Semantic Scholar
Immunomodulatory aspects in the progression and treatment of oral malignancy
N. Kondoh, M. Mizuno-Kamiya, Naoki Umemura, E. Takayama +4 more
2019Japanese Dental Science Review51 citations Open access
Semantic Scholar
Expression and physiological role of CCN4/Wnt‐induced secreted protein 1 mRNA splicing variants in chondrocytes
Takeshi Yanagita, S. Kubota, Harumi Kawaki, Kazumi Kawata +4 more
2007The FEBS Journal50 citations Open access
Semantic Scholar
Promotion of Bone Regeneration by CCN2 Incorporated into Gelatin Hydrogel
Takeshi Kikuchi, S. Kubota, K. Asaumi, Harumi Kawaki +6 more
2008Tissue Engineering. Part A41 citations Open access
Semantic Scholar
Possible role of LRP1, a CCN2 receptor, in chondrocytes.
Kazumi Kawata, T. Eguchi, S. Kubota, Harumi Kawaki +3 more
2006Biochemical and Biophysical Research Communications - BBRC37 citations
Semantic Scholar
Compressive Force‐Produced CCN2 Induces Osteocyte Apoptosis Through ERK1/2 Pathway
Kenji Hoshi, Harumi Kawaki, Ichiro Takahashi, N. Takeshita +8 more
2014Journal of Bone and Mineral Research35 citations
Semantic Scholar
Downregulation of rheumatoid arthritis‐related antigen RA‐A47 (HSP47/colligin‐2) in chondrocytic cell lines induces apoptosis and cell‐surface expression of RA‐A47 in association with CD9
T. Hattori, K. von der Mark, Harumi Kawaki, Y. Yutani +5 more
2005Journal of Cellular Physiology35 citations Open access
Semantic Scholar
Role of Mechanical Stress-induced Glutamate Signaling-associated Molecules in Cytodifferentiation of Periodontal Ligament Cells*
C. Fujihara, S. Yamada, N. Ozaki, N. Takeshita +3 more
2010Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Transcriptional induction of connective tissue growth factor/hypertrophic chondrocyte-specific 24 gene by dexamethasone in human chondrocytic cells.
S. Kubota, Norifumi H. Moritani, Harumi Kawaki, H. Mimura +2 more
2003Bone29 citations
Semantic Scholar
Novel effects of CCN3 that may direct the differentiation of chondrocytes
Danilo Janune, S. Kubota, Takashi Nishida, Harumi Kawaki +3 more
2011FEBS Letters28 citations
Semantic Scholar
Increased expression of matrilin-3 not only in osteoarthritic articular cartilage but also in cartilage-forming tumors, and down-regulation of SOX9 via epidermal growth factor domain 1-dependent signaling.
Jean-Baptiste Vincourt, J. Vignaud, F. Lionneton, F. Sirveaux +9 more
2008Arthritis & Rheumatism27 citations
Semantic Scholar
Posttranscriptional Regulation of Chicken ccn2 Gene Expression by Nucleophosmin/B23 during Chondrocyte Differentiation
Y. Mukudai, S. Kubota, Harumi Kawaki, S. Kondo +5 more
2008Molecular and Cellular Biology27 citations Open access
Semantic Scholar
Module-specific antibodies against human connective tissue growth factor: utility for structural and functional analysis of the factor as related to chondrocytes.
M. Minato, S. Kubota, Harumi Kawaki, Takashi Nishida +5 more
2004Journal of Biochemistry (Tokyo)27 citations
Semantic Scholar
Multiple activation of mitogen-activated protein kinases by purified independent CCN2 modules in vascular endothelial cells and chondrocytes in culture.
S. Kubota, Harumi Kawaki, Seiji Kondo, Gen Yosimichi +5 more
2006Biochimie26 citations
Semantic Scholar
Promotion of Hydroxyapatite-Associated, Stem Cell-Based Bone Regeneration by CCN2
M. Ono, S. Kubota, Takuo Fujisawa, W. Sonoyama +9 more
2008Cell Transplantation25 citations
Semantic Scholar
CCN2 as a Novel Molecule Supporting Energy Metabolism of Chondrocytes
Aya Maeda-Uematsu, S. Kubota, Harumi Kawaki, Kazumi Kawata +7 more
2014Journal of Cellular Biochemistry24 citations Open access
Semantic Scholar
Effect of 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin suggests abnormal palate development after palatal fusion
Hideto Imura, Tomohiro Yamada, K. Mishima, K. Fujiwara +5 more
2010Congenital Anomalies23 citations
Semantic Scholar
Promotion of attachment of human bone marrow stromal cells by CCN2.
M. Ono, S. Kubota, Takuo Fujisawa, W. Sonoyama +8 more
2007Biochemical and Biophysical Research Communications - BBRC21 citations
Semantic Scholar
Downregulation of a rheumatoid arthritis‐related antigen (RA‐A47) by ra‐a47 antisense oligonucleotides induces inflammatory factors in chondrocytes
T. Hattori, Harumi Kawaki, S. Kubota, Y. Yutani +3 more
2003Journal of Cellular Physiology20 citations
Semantic Scholar
A Tumor Suppressor Gene Product, Platelet‐Derived Growth Factor Receptor‐Like Protein Controls Chondrocyte Proliferation and Differentiation
Kazumi Kawata, S. Kubota, T. Eguchi, Eriko Aoyama +4 more
2017Journal of Cellular Biochemistry17 citations
Semantic Scholar
Increase of peripheral blood CD57+ T-cells in patients with oral squamous cell carcinoma.
M. Iida, E. Takayama, Kosuke Naganawa, K. Mitsudo +13 more
2014Anticancer Research15 citations
Semantic Scholar
Cellular communication network factor 3 in cartilage development and maintenance
S. Kubota, Harumi Kawaki, B. Perbal, Kazumi Kawata +2 more
2021Journal of cell communication and signaling14 citations Open access
Semantic Scholar
Mechanisms of the immunosuppressive effects of mouse adipose tissue-derived mesenchymal stromal cells on mouse alloreactively stimulated spleen cells
R. Nagaya, M. Mizuno-Kamiya, E. Takayama, Harumi Kawaki +4 more
2013Experimental and Therapeutic Medicine14 citations Open access
Semantic Scholar
Association of the metastatic phenotype with CCN family members among breast and oral cancer cells
T. Ohgawara, S. Kubota, Harumi Kawaki, N. Kurio +7 more
2011Journal of cell communication and signaling14 citations Open access
Semantic Scholar
Tumor growth limited to subcutaneous site vs tumor growth in pulmonary site exhibit differential effects on systemic immunities.
Junko Masuda, E. Takayama, W. Strober, Ayano Satoh +15 more
2017Oncology Report13 citations Open access
Semantic Scholar
Role of CCN2 in Amino Acid Metabolism of Chondrocytes
Yurika Murase, T. Hattori, Eriko Aoyama, Takashi Nishida +6 more
2016Journal of Cellular Biochemistry12 citations Open access
Semantic Scholar
RFX1‐mediated CCN3 induction that may support chondrocyte survival under starved conditions
Tomomi Mizukawa, Takashi Nishida, Sho Akashi, Kazumi Kawata +5 more
2021Journal of Cellular Physiology11 citations Open access
Semantic Scholar
Thrombopoietic-mesenchymal interaction that may facilitate both endochondral ossification and platelet maturation via CCN2
K. Sumiyoshi, S. Kubota, R. A. Furuta, K. Yasui +6 more
2009Journal of cell communication and signaling10 citations Open access
Semantic Scholar
The luminance ratio of autofluorescence in a xenograft mouse model is stable through tumor growth stages
S. Sumi, Naoki Umemura, M. Adachi, Takahisa Ohta +5 more
2018Clinical and Experimental Dental Research9 citations Open access
Semantic Scholar
Metastasized murine oral squamous cell carcinoma cells induce intratumoral polymorphonuclear myeloid derived suppressor cells.
S. Sumi, Naoki Umemura, E. Takayama, E. Ohkoshi +6 more
2017Oncology Report9 citations Open access
Semantic Scholar
Novel Enzyme-Linked Immunosorbent Assay Systems for the Quantitative Analysis of Connective Tissue Growth Factor (CTGF/Hcs24/CCN2): Detection of HTLV-I Tax-Induced CTGF from a Human Carcinoma Cell Line
Harumi Kawaki, S. Kubota, M. Minato, Norifumi H. Moritani +6 more
2003DNA and Cell Biology9 citations
Semantic Scholar
Effects of multi-components released from S-PRG filler on the activities of human dental pulp-derived stem cells.
Hiroshi Ishigure, Harumi Kawaki, K. Shintani, Kyohei Ueno +5 more
2021Dental materials journal7 citations Open access
Semantic Scholar
Gene expression analyses associated with malignant phenotypes of metastatic sub-clones derived from a mouse oral squamous cell carcinoma Sq-1979 cell line.
Mitsutaka Adachi, M. Mizuno-Kamiya, E. Takayama, Harumi Kawaki +8 more
2017Oncology Letters7 citations Open access
Semantic Scholar
Producing Capabilities of Interferon-gamma and Interleukin-10 in Peripheral Blood from Oral Squamous Cell Carcinoma Patients
Kosuke Naganawa, E. Takayama, M. Adachi, K. Mitsudo +10 more
2015Open Dentistry Journal7 citations Open access
Semantic Scholar
Design and utility of CCN2 anchor peptide aptamers.
Harumi Kawaki, S. Kubota, Eriko Aoyama, N. Fujita +4 more
2010Biochimie7 citations
Semantic Scholar
Do not overwork: cellular communication network factor 3 for life in cartilage
S. Kubota, Harumi Kawaki, B. Perbal, M. Takigawa +3 more
2023Journal of cell communication and signaling6 citations Open access
Semantic Scholar
Enhanced production of IL-2 from anti-CD3 antibody-stimulated mouse spleen cells by artepillin C, a major component of Brazilian green propolis.
Hanemi Tsuruta, M. Mizuno-Kamiya, Moe Takahashi, Megumi Ando +8 more
2022Journal of Oral Biosciences5 citations
Semantic Scholar
Effects of silica sputtering on adhesion between zirconia and composite resin cores.
M. Uno, Harumi Kawaki, H. Ishigami, Y. Yokogawa +1 more
2021Dental materials journal4 citations Open access
Semantic Scholar
Immunosuppressive Effect of Mesenchymal Stromal Cells is Enhanced by IL-1α from Oral Squamous Cell Carcinoma Cells
Hiroe Morimoto-Ito, M. Mizuno-Kamiya, Naoki Umemura, Yoshinori Inagaki +5 more
2019Open Dentistry Journal4 citations Open access
Semantic Scholar
The producing capabilities of Interferon-γ and Interleukin-10 of spleen cells in primary and metastasized oral squamous cell carcinoma cells-implanted mice
Yasuka Azuma, M. Mizuno-Kamiya, E. Takayama, Harumi Kawaki +4 more
20174 citations
Semantic Scholar
Evaluation of the mechanical properties and biocompatibility of gypsum-containing calcium silicate cements.
Y. Hayashi, Harumi Kawaki, M. Hori, K. Shintani +6 more
2021Dental materials journal3 citations Open access
Semantic Scholar
Augmented secretion of IL-1α from mouse oral squamous cell carcinoma (OSCC) cells caused by serum deprivation and hypoxia promotes immune suppressive activity of mesenchymal stromal cells.
Akihiro Matsunami, M. Mizuno-Kamiya, Harumi Kawaki, E. Takayama +6 more
2021Journal of Oral Biosciences3 citations
Semantic Scholar
Suppressive effect of mesenchymal stromal cells on interferon-γ-producing capability of spleen cells was specifically enhanced through humoral mediator(s) from mouse oral squamous cell carcinoma Sq-1979 Cells In Vitro
T. Inagaki, M. Mizuno-Kamiya, E. Takayama, Harumi Kawaki +4 more
20183 citations Open access
Semantic Scholar
Bioactivity of human dental pulp-derived stem cells with boron-controlled S-PRG filler eluate by anion exchange.
Y. Tatsumi, Harumi Kawaki, K. Shintani, Kyohei Ueno +4 more
2024Dental materials journal2 citations Open access
Semantic Scholar
Enhanced production of IL-2 from anti-CD3 antibody-stimulated mouse spleen cells by caffeic acid phenethyl ester, a major component of Chinese propolis.
Megumi Ando, Moe Takahashi, M. Mizuno-Kamiya, Hiroe Morimoto-Ito +8 more
2023Journal of Oral Biosciences2 citations
Semantic Scholar

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M. Takigawa×28
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S. Kubota×27
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N. Kondoh×16
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E. Takayama×15
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Takashi Nishida

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Kazumi Kawata×9

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