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M. Takigawa · SciRah

Researcher profile · Semantic Scholar

M. Takigawa

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M. Takigawa — researcher profile on SciRah

h-index: 67
Works: 400
Citations: 15K

Most-cited papers

Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment
T. Eguchi, C. Sogawa, Yuka Okusha, Kenta Uchibe +17 more
2018PLoS ONE113 citations Open access
Semantic Scholar
Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer
Kisho Ono, C. Sogawa, Hotaka Kawai, M. T. Tran +13 more
2020Journal of Extracellular Vesicles81 citations Open access
Semantic Scholar
Depletion of Lipid Efflux Pump ABCG1 Triggers the Intracellular Accumulation of Extracellular Vesicles and Reduces Aggregation and Tumorigenesis of Metastatic Cancer Cells
Yuri Namba, C. Sogawa, Yuka Okusha, Hotaka Kawai +11 more
2018Frontiers in Oncology75 citations Open access
Semantic Scholar
Low-intensity pulsed ultrasound (LIPUS) treatment of cultured chondrocytes stimulates production of CCN family protein 2 (CCN2), a protein involved in the regeneration of articular cartilage: mechanism underlying this stimulation.
Takashi Nishida, S. Kubota, Eriko Aoyama, Nobuyasu Yamanaka +2 more
2017Osteoarthritis and Cartilage56 citations Open access
Semantic Scholar
UPR transducer BBF2H7 allows export of type II collagen in a cargo- and developmental stage–specific manner
Tokiro Ishikawa, Takuya Toyama, Yuki Nakamura, Kentaro Tamada +10 more
2017Journal of Cell Biology55 citations Open access
Semantic Scholar
Intracellular MMP3 Promotes HSP Gene Expression in Collaboration With Chromobox Proteins
T. Eguchi, Stuart K. Calderwood, M. Takigawa, S. Kubota +1 more
2017Journal of Cellular Biochemistry48 citations Open access
Semantic Scholar
Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer
Yuka Okusha, T. Eguchi, M. T. Tran, C. Sogawa +10 more
2020Cancers45 citations Open access
Semantic Scholar
Antiparkinson Drug Benztropine Suppresses Tumor Growth, Circulating Tumor Cells, and Metastasis by Acting on SLC6A3/DAT and Reducing STAT3
C. Sogawa, T. Eguchi, M. T. Tran, M. Ishige +10 more
2020Cancers41 citations Open access
Semantic Scholar
Low‐intensity pulsed ultrasound stimulation promotes osteoblast differentiation through hedgehog signaling
Kenichi Matsumoto, T. Shimo, N. Kurio, Tatsuo Okui +9 more
2018Journal of Cellular Biochemistry41 citations
Semantic Scholar
Catabolic effects of FGF-1 on chondrocytes and its possible role in osteoarthritis
A. El-Seoudi, T. Abdelkader, Takashi Nishida, T. Eguchi +3 more
2017Journal of cell communication and signaling33 citations Open access
Semantic Scholar
CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage
Miho Kuwahara, Koichi Kadoya, S. Kondo, Shanqi Fu +10 more
2020International Journal of Molecular Sciences27 citations Open access
Semantic Scholar
The CCN Proteins: An Overview.
M. Takigawa
2017Methods in molecular biology27 citations
Semantic Scholar
CCN family protein 2 (CCN2) promotes the early differentiation, but inhibits the terminal differentiation of skeletal myoblasts.
Takashi Nishida, S. Kubota, Eriko Aoyama, Danilo Janune +2 more
2015Journal of Biochemistry (Tokyo)27 citations Open access
Semantic Scholar
An early history of CCN2/CTGF research: the road to CCN2 via hcs24, ctgf, ecogenin, and regenerin
M. Takigawa
2018Journal of cell communication and signaling26 citations Open access
Semantic Scholar
Novel role of CCN3 that maintains the differentiated phenotype of articular cartilage
Danilo Janune, T. Abdelkader, Eriko Aoyama, Takashi Nishida +3 more
2017Journal of Bone and Mineral Metabolism25 citations
Semantic Scholar
Possible reparative effect of low-intensity pulsed ultrasound (LIPUS) on injured meniscus
Yusuke Kamatsuki, Eriko Aoyama, T. Furumatsu, S. Miyazawa +6 more
2018Journal of cell communication and signaling23 citations Open access
Semantic Scholar
A Reporter System Evaluates Tumorigenesis, Metastasis, β-catenin/MMP Regulation, and Druggability
C. Sogawa, T. Eguchi, Yuka Okusha, Kisho Ono +8 more
2019Tissue Engineering. Part A21 citations Open access
Semantic Scholar
CTGF/CCN2 facilitates LRP4‐mediated formation of the embryonic neuromuscular junction
B. Ohkawara, A. Kobayakawa, Shunsuke Kanbara, T. Hattori +7 more
2020EMBO Reports19 citations Open access
Semantic Scholar
Suppression of adipocyte differentiation by low‐intensity pulsed ultrasound via inhibition of insulin signaling and promotion of CCN family protein 2
Takashi Nishida, Yurika Nagao, Satoko Hashitani, Nobuyasu Yamanaka +2 more
2020Journal of Cellular Biochemistry18 citations
Semantic Scholar
A Tumor Suppressor Gene Product, Platelet‐Derived Growth Factor Receptor‐Like Protein Controls Chondrocyte Proliferation and Differentiation
Kazumi Kawata, S. Kubota, T. Eguchi, Eriko Aoyama +4 more
2017Journal of Cellular Biochemistry17 citations
Semantic Scholar
Physical interaction of CCN2 with diverse growth factors involved in chondrocyte differentiation during endochondral ossification
H. Khattab, Eriko Aoyama, S. Kubota, M. Takigawa
2015Journal of cell communication and signaling17 citations Open access
Semantic Scholar
Metabolic regulation of the CCN family genes by glycolysis in chondrocytes
Sho Akashi, Takashi Nishida, A. El-Seoudi, M. Takigawa +2 more
2017Journal of cell communication and signaling16 citations Open access
Semantic Scholar
Physiological role of urothelial cancer‐associated one long noncoding RNA in human skeletogenic cell differentiation
Takanori Ishikawa, Takashi Nishida, M. Ono, T. Takarada +8 more
2018Journal of Cellular Physiology14 citations
Semantic Scholar
Regulatory mechanism of CCN2 production by serotonin (5-HT) via 5-HT2A and 5-HT2B receptors in chondrocytes
Ayaka Hori, Takashi Nishida, S. Takashiba, S. Kubota +1 more
2017PLoS ONE14 citations Open access
Semantic Scholar
Selective Agonists of Nuclear Retinoic Acid Receptor Gamma Inhibit Growth of HCS-2/8 Chondrosarcoma Cells
William Shield, Ashley L Cellini, Hongying Tian, Kimberly Wilson +10 more
2019Journal of Orthopaedic Research13 citations Open access
Semantic Scholar
CCN2/CTGF binds the small leucine rich proteoglycan protein Tsukushi
K. Ohta, Eriko Aoyama, Shah Adil Ishtiyaq Ahmad, Naofumi Ito +3 more
2018Journal of cell communication and signaling13 citations Open access
Semantic Scholar
Fibroblast Growth Factors and Cellular Communication Network Factors: Intimate Interplay by the Founding Members in Cartilage
S. Kubota, Eriko Aoyama, M. Takigawa, Takashi Nishida
2022International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
Role of CCN2 in Amino Acid Metabolism of Chondrocytes
Yurika Murase, T. Hattori, Eriko Aoyama, Takashi Nishida +6 more
2016Journal of Cellular Biochemistry12 citations Open access
Semantic Scholar
RFX1‐mediated CCN3 induction that may support chondrocyte survival under starved conditions
Tomomi Mizukawa, Takashi Nishida, Sho Akashi, Kazumi Kawata +5 more
2021Journal of Cellular Physiology11 citations Open access
Semantic Scholar
Regulation of cellular communication factor 2 (CCN2) in breast cancer cells via the cell-type dependent interplay between CCN2 and glycolysis.
Sho Akashi, Takashi Nishida, Tomomi Mizukawa, Kazumi Kawata +3 more
2020Journal of Oral Biosciences11 citations Open access
Semantic Scholar
Promoter Analyses of CCN Genes.
T. Eguchi, S. Kubota, M. Takigawa
2017Methods in molecular biology11 citations
Semantic Scholar
The BMP-2 mutant L51P: a BMP receptor IA binding-deficient inhibitor of noggin
H. Khattab, S. Kubota, M. Takigawa, T. Kuboki +1 more
2019Journal of Bone and Mineral Metabolism10 citations
Semantic Scholar
Elevated Expression of CCN3 in Articular Cartilage Induces Osteoarthritis in Hip Joints Irrespective of Age and Weight Bearing
Kazuki Hirose, Miho Kuwahara, E. Nakata, Tomonori Tetsunaga +6 more
2022International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Effect of Angiotensin II on Chondrocyte Degeneration and Protection via Differential Usage of Angiotensin II Receptors
Takashi Nishida, Sho Akashi, M. Takigawa, S. Kubota
2021International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Roles of matricellular CCN2 deposited by osteocytes in osteoclastogenesis and osteoblast differentiation
Takashi Nishida, S. Kubota, H. Yokoi, M. Mukoyama +1 more
2019Scientific Reports8 citations Open access
Semantic Scholar
CCN Proteins (Cellular Communication Network Factors): Expanding Their Repertoire Toward a New Concept.
M. Takigawa
2023Methods in molecular biology7 citations
Semantic Scholar
Do not overwork: cellular communication network factor 3 for life in cartilage
S. Kubota, Harumi Kawaki, B. Perbal, M. Takigawa +3 more
2023Journal of cell communication and signaling6 citations Open access
Semantic Scholar
Roles of Interaction between CCN2 and Rab14 in Aggrecan Production by Chondrocytes
M. Hoshijima, T. Hattori, Eriko Aoyama, Takashi Nishida +3 more
2020International Journal of Molecular Sciences6 citations Open access
Semantic Scholar
Production of Recombinant CCN2 Protein by Mammalian Cells.
Takashi Nishida, S. Kubota, M. Takigawa
2017Methods in molecular biology6 citations
Semantic Scholar
New functional aspects of CCN2 revealed by trans-omic approaches
S. Kubota, Aya Maeda-Uematsu, Takashi Nishida, M. Takigawa
20156 citations
Semantic Scholar
Bipartite regulation of cellular communication network factor 2 and fibroblast growth factor 1 genes by fibroblast growth factor 1 through histone deacetylase 1 and fork head box protein A1
A. Elseoudi, Takashi Nishida, Tomomi Mizukawa, T. Hattori +4 more
2021Journal of cell communication and signaling5 citations Open access
Semantic Scholar
Involvement of multiple CCN family members in platelets that support regeneration of joint tissues
Chikako Hara, S. Kubota, Takashi Nishida, Miki Hiasa +5 more
2016Modern Rheumatology5 citations Open access
Semantic Scholar
Correction: Cellular and molecular actions of CCN2/CTGF and its role under physiological and pathological conditions.
S. Kubota, M. Takigawa
2015Clinical science5 citations Open access
Semantic Scholar
Dual roles of cellular communication network factor 6 (CCN6) in the invasion and metastasis of oral cancer cells to bone via binding to BMP2 and RANKL
Hiroaki Hochi, S. Kubota, M. Takigawa, Takashi Nishida
2023Carcinogenesis4 citations Open access
Semantic Scholar
[The role of osteocytes in bone remodeling.]
Takashi Nishida, S. Kubota, M. Takigawa
2017Clinical calcium4 citations
Semantic Scholar
The Evaluation of Meniscus Regenerative Effects of LIPUS-Induced CCN Proteins: Induction by LIPUS of CCN2 and Meniscus-Related Genes in Cultured Meniscus Cells and Meniscus Tissues.
Yusuke Kamatsuki, Eriko Aoyama, T. Furumatsu, Toshifumi Ozaki +1 more
2023Methods in molecular biology3 citations
Semantic Scholar
Jiadifenolide induces the expression of cellular communication network factor (CCN) genes, and CCN2 exhibits neurotrophic activity in neuronal precursor cells derived from human induced pluripotent stem cells.
Masaki Shoji, M. Ueda, Megumi Nishioka, H. Minato +8 more
2019Biochemical and Biophysical Research Communications - BBRC3 citations Open access
Semantic Scholar
Proinsulin C-peptide regulates ribosomal RNA expression.
E. Lindahl, Ulrika Nyman, F. Zaman, C. Palmberg +6 more
2017Journal of Biological Chemistry3 citations Open access
Semantic Scholar
Evaluation of Molecular Interaction between CCN2 Protein and Its Binding Partners by Surface Plasmon Resonance (SPR).
Eriko Aoyama, M. Takigawa
2017Methods in molecular biology3 citations
Semantic Scholar
Cell Biological Assays for Measuring Angiogenic Activities of CCN Proteins.
T. Shimo, M. Takigawa
2017Methods in molecular biology3 citations
Semantic Scholar

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S. Kubota×33
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S. Kubota — researcher profile on SciRah
Takashi Nishida×23
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Takashi Nishida — researcher profile on SciRah
Eriko Aoyama×18
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Eriko Aoyama — researcher profile on SciRah
T. Eguchi×10
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T. Hattori — researcher profile on SciRah

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K. Kozaki — researcher profile on SciRah

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C. Sogawa — researcher profile on SciRah

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Yuka Okusha — researcher profile on SciRah

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K. Okamoto — researcher profile on SciRah

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Kisho Ono — researcher profile on SciRah

S. Calderwood×5

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S. Calderwood — researcher profile on SciRah

Kazumi Kawata×5

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Kazumi Kawata — researcher profile on SciRah