Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

R. Mallis · SciRah

Researcher profile · Semantic Scholar

R. Mallis

Share profile

R. Mallis — researcher profile on SciRah

h-index: 20
Works: 75
Citations: 2,030

Most-cited papers

Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A
K. Brazin, R. Mallis, D. Fulton, A. Andreotti
2002Proceedings of the National Academy of Sciences of the United States of America267 citations Open access
Semantic Scholar
Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime
D. Das, Yinnian Feng, R. Mallis, Xiao-Long Li +7 more
2015Proceedings of the National Academy of Sciences of the United States of America247 citations Open access
Semantic Scholar
Oxidative modification of H-ras: S-thiolation and S-nitrosylation of reactive cysteines.
R. Mallis, J. Buss, James A. Thomas
2001Biochemical Journal181 citations Open access
Semantic Scholar
Mechanosensing drives acuity of αβ T-cell recognition
Yinnian Feng, K. Brazin, E. Kobayashi, R. Mallis +2 more
2017Proceedings of the National Academy of Sciences of the United States of America172 citations Open access
Semantic Scholar
Aging and oxidation of reactive protein sulfhydryls.
James A. Thomas, R. Mallis
2001Experimental Gerontology133 citations
Semantic Scholar
Structural characterization of a proline-driven conformational switch within the Itk SH2 domain
R. Mallis, K. Brazin, D. Fulton, A. Andreotti
2002Nature Structural Biology122 citations
Semantic Scholar
Irreversible Thiol Oxidation in Carbonic Anhydrase III: Protection by S-Glutathiolation and Detection in Aging Rats
R. Mallis, Michael J. Hamann, Wei Zhao, Tie-Quan Zhang +2 more
2002Biological chemistry102 citations Open access
Semantic Scholar
TCR Mechanobiology: Torques and Tunable Structures Linked to Early T Cell Signaling
Sun Taek Kim, Yongdae Shin, K. Brazin, R. Mallis +4 more
2012Front. Immun.90 citations Open access
Semantic Scholar
Crystal structure of S‐glutathiolated carbonic anhydrase III
R. Mallis, B. Poland, T. K. Chatterjee, R. Fisher +3 more
2000FEBS Letters76 citations
Semantic Scholar
Pre-TCR ligand binding impacts thymocyte development before αβTCR expression
R. Mallis, Kevin Bai, H. Arthanari, R. E. Hussey +9 more
2015Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
Structural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC Discrimination
K. Brazin, R. Mallis, D. Das, Yinnian Feng +5 more
2015Frontiers in Immunology64 citations Open access
Semantic Scholar
The T cell antigen receptor α transmembrane domain coordinates triggering through regulation of bilayer immersion and CD3 subunit associations
K. Brazin, R. Mallis, A. Boeszoermenyi, Yinnian Feng +11 more
2018Immunity62 citations Open access
Semantic Scholar
The αβTCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site
W. Hwang, R. Mallis, Matthew J. Lang, E. Reinherz
2020Proceedings of the National Academy of Sciences of the United States of America61 citations Open access
Semantic Scholar
Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands*♦
D. Das, R. Mallis, J. Duke-Cohan, R. E. Hussey +5 more
2016Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Effect of S-nitrosothiols on cellular glutathione and reactive protein sulfhydryls.
R. Mallis, James A. Thomas
2000Archives of Biochemistry and Biophysics41 citations
Semantic Scholar
CTL recognition of a protective immunodominant influenza A virus nucleoprotein epitope utilizes a highly restricted Vbeta but diverse Valpha repertoire: functional and structural implications.
W. Zhong, S. Dixit, R. Mallis, H. Arthanari +4 more
2007Journal of Molecular Biology31 citations
Semantic Scholar
Molecular design of the γδT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing
R. Mallis, J. Duke-Cohan, D. Das, Akitsu Aoi +14 more
2021Proceedings of the National Academy of Sciences of the United States of America28 citations Open access
Semantic Scholar
Pre–T cell receptors topologically sample self-ligands during thymocyte β-selection
Xiao-Long Li, R. Mizsei, K. Tan, R. Mallis +10 more
2020Science26 citations Open access
Semantic Scholar
NMR: An Essential Structural Tool for Integrative Studies of T Cell Development, pMHC Ligand Recognition and TCR Mechanobiology.
R. Mallis, K. Brazin, J. Duke-Cohan, W. Hwang +5 more
2019Journal of Biomolecular NMR25 citations Open access
Semantic Scholar
Constitutively Oxidized CXXC Motifs within the CD3 Heterodimeric Ectodomains of the T Cell Receptor Complex Enforce the Conformation of Juxtaposed Segments*
K. Brazin, R. Mallis, Chen Li, D. Keskin +6 more
2014Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Pre-T cell receptor Self-MHC Sampling Restricts Thymocyte Dedifferentiation
J. Duke-Cohan, Akitsu Aoi, R. Mallis, Cameron M. Messier +5 more
2022bioRxiv20 citations Open access
Semantic Scholar
A Conserved Hydrophobic Patch on Vβ Domains Revealed by TCRβ Chain Crystal Structures: Implications for Pre-TCR Dimerization
Bo Zhou, Qiang Chen, R. Mallis, Hongmin Zhang +3 more
2011Front. Immun.19 citations Open access
Semantic Scholar
Protein S-Thiolation, S-Nitrosylation, and Irreversible Sulfhydryl Oxidation: Roles in Redox Regulation
James A. Thomas, R. Mallis, H. Sies
200318 citations
Semantic Scholar
Parsing digital or analog TCR performance through piconewton forces
Akitsu Aoi, Eiji Kobayashi, Yinnian Feng, Hannah M. Stephens +15 more
2024Science Advances16 citations Open access
Semantic Scholar
NMR-directed design of pre-TCRβ and pMHC molecules implies a distinct geometry for pre-TCR relative to αβTCR recognition of pMHC
R. Mallis, H. Arthanari, Matthew J. Lang, E. Reinherz +1 more
2017Journal of Biological Chemistry13 citations Open access
Semantic Scholar
Cryopreservation of rooster semen in thirteen and sixteen percent glycerol.
S. Gill, E. Buss, R. Mallis
1996Poultry Science13 citations Open access
Semantic Scholar
Biophysical and Structural Features of αβT‐Cell Receptor Mechanosensing: A Paradigmatic Shift in Understanding T‐Cell Activation
R. Mallis, K. Brazin, J. Duke-Cohan, Akitsu Aoi +16 more
2024Immunological Reviews12 citations Open access
Semantic Scholar
Efficient and economic protein labeling for NMR in mammalian expression systems: Application to a preT‐cell and T‐cell receptor protein
R. Mallis, Jonathan J. Lee, A. van den Berg, K. Brazin +9 more
2024Protein Science11 citations
Semantic Scholar
Asymmetric framework motion of TCRαβ controls load-dependent peptide discrimination
A. Chang-Gonzalez, R. Mallis, Matthew J. Lang, E. Reinherz +1 more
2023bioRxiv6 citations Open access
Semantic Scholar
Asymmetric framework motion of TCRαβ controls load-dependent peptide discrimination
A. Chang-Gonzalez, R. Mallis, Matthew J. Lang, E. Reinherz +1 more
2024eLife5 citations Open access
Semantic Scholar
Measuring αβ T-Cell Receptor-Mediated Mechanosensing Using Optical Tweezers Combined with Fluorescence Imaging.
Hannah M. Stephens, K. Brazin, R. Mallis, Yinnian Feng +3 more
2022Methods in molecular biology5 citations
Semantic Scholar
A general chemical crosslinking strategy for structural analyses of weakly interacting proteins applied to preTCR–pMHC complexes
R. Mizsei, Xiao-Long Li, Wan-Na Chen, Mónika Szabó +4 more
2021Journal of Biological Chemistry5 citations Open access
Semantic Scholar
Backbone Resonance Assignment of N15, N30 and D10 T cell Receptor β subunits
R. Mallis, E. Reinherz, G. Wagner, H. Arthanari
2015Biomolecular NMR Assignments5 citations Open access
Semantic Scholar
Immunodominant-peptide recognition: beta testing TCRalphabeta.
Jia-Huai Wang, R. Mallis, E. Reinherz
2008Immunity4 citations Open access
Semantic Scholar
Atomistic TCR-ligand interactions instruct memory T-cell differentiation
Akitsu Aoi, Ke-Min Tan, R. Mallis, Matthew A. Booker +16 more
2025bioRxiv2 citations
Semantic Scholar
Load-based divergence in the dynamic allostery of two TCRs recognizing the same pMHC
A. Chang-Gonzalez, Akitsu Aoi, R. Mallis, Matthew J. Lang +2 more
2024bioRxiv2 citations Open access
Semantic Scholar
A Conserved Hydrophobic Patch on V \(\beta\) Domains Revealed by TCR \(\beta\) Chain Crystal Structures: Implications for Pre-TCR Dimerization
Bo Zhou, Qiang Chen, R. Mallis, Hongmin Zhang +3 more
20112 citations
Semantic Scholar
Cancers modulate processing and presentation of p53 neoantigens to evade T cell detection
Koji Haratani, Bruce R. Reinhold, J. Duke-Cohan, Caroline G. Fahey +22 more
2026Immunity1 citations Open access
Semantic Scholar
Cancers modulate p53 truncal neoantigen display to evade T cell detection
Koji Haratani, Bruce R. Reinhold, J. Duke-Cohan, Caroline G. Fahey +22 more
2025bioRxiv1 citations
Semantic Scholar
Load-dependent conformational behavior of the A6 TCR HLA-A2/Tax pMHC complex
A. Chang-Gonzalez, R. Mallis, Matthew J. Lang, E. Reinherz +1 more
2022Biophysical Journal1 citations Open access
Semantic Scholar
Proteins: the complete works.
R. Mallis, K. Brazin, Joseph M. Jez, Emma Wilson +3 more
2001TIBS -Trends in Biochemical Sciences. Regular ed1 citations
Semantic Scholar
BPS2026 – Molecular dynamics simulations under load of three distinct T cell receptors recognizing the same truncal tumor TP53 neoantigen reveal differential stability of their TCR-pHLA complexes
Mahoora N. Naghinejad, R. Mallis, Matthew J. Lang, E. Reinherz +1 more
2026Biophysical Journal0 citations
Semantic Scholar
Atomistic TCR-ligand interactions instruct memory T-cell differentiation 2330211
Akitsu Aoi, Ke-Min Tan, R. Mallis, Matthew A. Booker +17 more
2026Journal of Immunology0 citations Open access
Semantic Scholar
Extended local deuteration of leucine enhances methyl NMR of large proteins expressed in eukaryotic cells
Sebastian Schindler, A. Dubey, R. Mallis, D. Radeva +6 more
2026Chemical Communications0 citations Open access
Semantic Scholar
BPS2026 – Loading-direction-dependent responses of alpha beta T cell receptors
Wonmuk Hwang, Akitsu Aoi, K. Brazin, J. Duke-Cohan +7 more
2026Biophysical Journal0 citations
Semantic Scholar
Atomistic TCR-pMHC interactions bias CD8 memory fate within a single antigen-specific repertoire.
Akitsu Aoi, Ke-Min Tan, R. Mallis, Matthew A. Booker +17 more
2026Cell Reports0 citations Open access
Semantic Scholar
Heterogeneity of mechanical responses of αβ T-cell receptors 2257683
Wonmuk Hwang, Akitsu Aoi, K. Brazin, J. Duke-Cohan +7 more
2026Journal of Immunology0 citations
Semantic Scholar
Dynamic allostery of T-cell receptor chassis motion for pMHC discrimination under applied load 2768
Wonmuk Hwang, A. Chang-Gonzalez, Evan H. Kirkpatrick, Hannah M. Stephens +3 more
2025Journal of Immunology0 citations
Semantic Scholar
BPS2025 - Kinetic model of load-dependent TCR-pMHC conformational transition and dissociation
Wonmuk Hwang, Hannah M. Stephens, R. Mallis, E. Reinherz +1 more
2025Biophysical Journal0 citations Open access
Semantic Scholar
BPS2025 - Allosteric control of TCRγδ innate-like interface by the introduction of Cαβ domains
Sofiya B. Bettencourt, R. Mallis, Matthew J. Lang, E. Reinherz +1 more
2025Biophysical Journal0 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

E. Reinherz×40
Invite
E. Reinherz — researcher profile on SciRah
K. Brazin×19
Invite
K. Brazin — researcher profile on SciRah
J. Duke-Cohan×16
Invite
J. Duke-Cohan — researcher profile on SciRah
Matthew J. Lang×15
Invite
Matthew J. Lang — researcher profile on SciRah

Matthew J. Lang

×14

Invite

Matthew J. Lang — researcher profile on SciRah

Invite

G. Wagner — researcher profile on SciRah

Wonmuk Hwang×13

Invite

Wonmuk Hwang — researcher profile on SciRah

Invite

Akitsu Aoi — researcher profile on SciRah

H. Arthanari×11

Invite

H. Arthanari — researcher profile on SciRah

Jia-Huai Wang×8

Invite

Jia-Huai Wang — researcher profile on SciRah

Invite

W. Hwang — researcher profile on SciRah

Hannah M. Stephens×8

Invite

Hannah M. Stephens — researcher profile on SciRah