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H. Mehanna · SciRah

Researcher profile · Semantic Scholar

H. Mehanna

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H. Mehanna — researcher profile on SciRah

h-index: 49
Works: 332
Citations: 11K

Most-cited papers

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC)
E. Cohen, R. B. Bell, Carlo Bifulco, B. Burtness +15 more
2019Journal of Immunotherapy for Cancer622 citations Open access
Semantic Scholar
Safety and Efficacy of Durvalumab With or Without Tremelimumab in Patients With PD-L1–Low/Negative Recurrent or Metastatic HNSCC: The Phase 2 CONDOR Randomized Clinical Trial
L. Siu, C. Even, R. Mesía, É. Remenár +17 more
2019JAMA Oncology279 citations Open access
Semantic Scholar
Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis.
H. Mehanna, M. Taberna, C. von Buchwald, S. Tous +26 more
2023The Lancet Oncology254 citations Open access
Semantic Scholar
Acoustofluidic Salivary Exosome Isolation: A Liquid Biopsy Compatible Approach for Human Papillomavirus-Associated Oropharyngeal Cancer Detection.
Zeyu Wang, Feng Li, Joseph Rufo, Chuyi Chen +14 more
2019Journal of Molecular Diagnostics138 citations Open access
Semantic Scholar
International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ‐HN43: Phase IV
S. Singer, C. D. Amdal, E. Hammerlid, I. Tomaszewska +29 more
2019Head and Neck129 citations Open access
Semantic Scholar
Recommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an international consensus
H. Mehanna, J. Hardman, J. Shenson, Ahmad K. Abou-Foul +44 more
2020The Lancet Oncology107 citations Open access
Semantic Scholar
WEE1 Inhibitor: Clinical Development
A. Kong, H. Mehanna
2021Current Oncology Reports88 citations Open access
Semantic Scholar
Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer
J. Brooks, A. N. Menezes, M. Ibrahim, L. Archer +23 more
2019Clinical Cancer Research82 citations Open access
Semantic Scholar
Transoral tongue base mucosectomy for the identification of the primary site in the work-up of cancers of unknown origin: Systematic review and meta-analysis.
S. Farooq, S. Khandavilli, J. Dretzke, D. Moore +11 more
2019Oral Oncology79 citations Open access
Semantic Scholar
De-Escalation After DE-ESCALATE and RTOG 1016: A Head and Neck Cancer InterGroup Framework for Future De-Escalation Studies
H. Mehanna, D. Rischin, S. Wong, V. Grégoire +10 more
2020Journal of Clinical Oncology76 citations Open access
Semantic Scholar
Emergency changes in international guidelines on treatment for head and neck cancer patients during the COVID-19 pandemic
Aline Lauda Freitas Chaves, A. Castro, G. Marta, Gilberto Castro +16 more
2020Oral Oncology57 citations Open access
Semantic Scholar
Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI
A. Kreimer, A. Chaturvedi, L. Alemany, D. Anantharaman +27 more
2020Oral Oncology55 citations Open access
Semantic Scholar
Collagen Induces a More Proliferative, Migratory and Chemoresistant Phenotype in Head and Neck Cancer via DDR1
Sook Ling Lai, M. Tan, R. Hollows, M. Robinson +12 more
2019Cancers55 citations Open access
Semantic Scholar
Lack of predictive tools for conventional and targeted cancer therapy: Barriers to biomarker development and clinical translation
N. Batis, J. Brooks, K. Payne, N. Sharma +2 more
2021Advanced Drug Delivery Reviews49 citations Open access
Semantic Scholar
Oral Human Papillomavirus Prevalence and Genotyping Among a Healthy Adult Population in the US
A. Giuliano, Marisa A. Felsher, T. Waterboer, H. Mirghani +11 more
2023JAMA Otolaryngology - Head and Neck Surgery47 citations Open access
Semantic Scholar
Head and Neck Cancer International Group (HNCIG) Consensus Guidelines for the delivery of postoperative radiation therapy in complex cutaneous squamous cell carcinoma of the head and neck (cSCCHN).
S. Porceddu, C. Daniels, S. Yom, H. Liu +9 more
2020International Journal of Radiation Oncology, Biology, Physics40 citations Open access
Semantic Scholar
A digital score of tumour‐associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma
M. Shaban, S. E. Ahmed Raza, Maria Hassan, A. Jamshed +10 more
2021Journal of Pathology38 citations Open access
Semantic Scholar
Diagnostic challenges and prognostic implications of extranodal extension in head and neck cancer: a state of the art review and gap analysis
C. Henson, Ahmad K. Abou-Foul, D. Morton, Lachlan McDowell +10 more
2023Frontiers in Oncology35 citations Open access
Semantic Scholar
Modelling human papillomavirus biology in oropharyngeal keratinocytes
S. Roberts, D. Evans, H. Mehanna, Joanna L. Parish
2019Philosophical Transactions of the Royal Society of London. Biological Sciences35 citations Open access
Semantic Scholar
Recurrence of Papillary Thyroid Cancer: A Systematic Appraisal of Risk Factors
H. Nieto, C. Thornton, Katie Brookes, Albert Antao Nobre de Menezes +10 more
2021Journal of Clinical Endocrinology and Metabolism34 citations Open access
Semantic Scholar
Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol
A. Kong, J. Good, A. Kirkham, J. Savage +12 more
2020BMJ Open31 citations Open access
Semantic Scholar
Clinicians' Views of Patient-initiated Follow-up in Head and Neck Cancer: a Qualitative Study to Inform the PETNECK2 Trial
A. Lorenc, M. Wells, T. Fulton-Lieuw, P. Nankivell +25 more
2021Clinics in oncology30 citations Open access
Semantic Scholar
Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial.
J. Wilson, J. O'Hara, T. Fouweather, T. Homer +19 more
2023The Lancet28 citations Open access
Semantic Scholar
Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: a GORTEC internationally-reviewed HNCIG-endorsed consensus.
F. Carsuzaa, M. Lapeyre, V. Grégoire, P. Maingon +47 more
2021Radiotherapy and Oncology26 citations Open access
Semantic Scholar
Definition of locally recurrent head and neck squamous cell carcinoma: a systematic review and proposal for the Odense–Birmingham definition
M. Rohde, Tine Rosenberg, Manan Pareek, P. Nankivell +3 more
2020European Archives of Oto-Rhino-Laryngology26 citations Open access
Semantic Scholar
Circulating Tumour Cell Biomarkers in Head and Neck Cancer: Current Progress and Future Prospects
K. Payne, J. Brooks, Rachel Spruce, N. Batis +3 more
2019Cancers26 citations Open access
Semantic Scholar
Concordance of p16INK4a and E6*I mRNA among HPV-DNA-Positive Oropharyngeal, Laryngeal, and Oral Cavity Carcinomas from the ICO International Study
M. Mena, X. Wang, S. Tous, B. Quirós +16 more
2022Cancers23 citations Open access
Semantic Scholar
Upper Aerodigestive Tract Squamous Cell Carcinomas Show Distinct Overall DNA Methylation Profiles and Different Molecular Mechanisms behind WNT Signaling Disruption
S. Soares-Lima, H. Mehanna, D. Camuzi, P. T. de Souza-Santos +12 more
2021Cancers21 citations Open access
Semantic Scholar
Toxicity Reduction in the Treatment of HPV Positive Oropharyngeal Cancer: Emerging Combined Modality Approaches
S. Deschuymer, H. Mehanna, S. Nuyts
2018Frontiers in Oncology21 citations Open access
Semantic Scholar
Practical guidance for running late-phase platform protocols for clinical trials: lessons from experienced UK clinical trials units
Sharon B. Love, F. Cafferty, C. Snowdon, K. Carty +32 more
2022Trials20 citations Open access
Semantic Scholar
PTTG and PBF functionally interact with p53 and predict overall survival in head and neck cancer
Martin L Read, B. Modasia, A. Fletcher, Rebecca J. Thompson +11 more
2018Cancer Research20 citations Open access
Semantic Scholar
Dose-escalated intensity-modulated radiotherapy in patients with locally advanced laryngeal and hypopharyngeal cancers: ART DECO, a phase III randomised controlled trial.
C. Nutting, C. Griffin, P. Sanghera, B. Foran +26 more
2021European Journal of Cancer19 citations Open access
Semantic Scholar
Feasibility of mass cytometry proteomic characterisation of circulating tumour cells in head and neck squamous cell carcinoma for deep phenotyping
K. Payne, J. Brooks, N. Batis, Naeem Khan +4 more
2023British Journal of Cancer18 citations Open access
Semantic Scholar
The hidden curve behind COVID-19 outbreak: the impact of delay in treatment initiation in cancer patients and how to mitigate the additional risk of dying—the head and neck cancer model
L. L. Matos, C. H. Forster, G. Marta, Gilberto Castro +27 more
2020Cancer Causes and Control18 citations Open access
Semantic Scholar
Lead Time to Recurrence After Posttreatment Plasma and Saliva HPV DNA Testing in Patients With Low-Risk HPV Oropharynx Cancer.
J. Califano, Andrew Yousef, Heba H. Mostafa, A. Valsamakis +8 more
2023JAMA Otolaryngology - Head and Neck Surgery17 citations Open access
Semantic Scholar
The anti-tumour activity of DNA methylation inhibitor 5-aza-2′-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress
Hannah J. Gleneadie, Amy H. Baker, N. Batis, J. Bryant +14 more
2020Cancer Letters17 citations Open access
Semantic Scholar
Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma
J. Bryant, N. Batis, A. Franke, Gabriella Clancey +10 more
2019OncoTarget17 citations Open access
Semantic Scholar
Immediate Sample Fixation Increases Circulating Tumour Cell (CTC) Capture and Preserves Phenotype in Head and Neck Squamous Cell Carcinoma: Towards a Standardised Approach to Microfluidic CTC Biomarker Discovery
K. Payne, J. Brooks, G. Taylor, N. Batis +4 more
2021Cancers16 citations Open access
Semantic Scholar
Concurrent cisplatin or cetuximab with radiotherapy for HPV-positive oropharyngeal cancer: Medical resource use, costs, and quality-adjusted survival from the De-ESCALaTE HPV trial
David A. Jones, P. Mistry, M. Dalby, T. Fulton-Lieuw +4 more
2019European Journal of Cancer16 citations Open access
Semantic Scholar
Exploring the views of patients' and their family about patient‐initiated follow‐up in head and neck cancer: A mixed methods study
A. Lorenc, C. Greaves, J. Duda, J. Brett +8 more
2022European Journal of Cancer Care15 citations Open access
Semantic Scholar
Methodological approach for determining the Minimal Important Difference and Minimal Important Change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the Swallowing scale
S. Singer, E. Hammerlid, I. Tomaszewska, C. D. Amdal +27 more
2021Quality of Life Research14 citations Open access
Semantic Scholar
Post‐Treatment Head and Neck Cancer Care: National Audit and Analysis of Current Practice in the United Kingdom
Matthew Ellis, G. Garas, J. Hardman, Maha Khan +6 more
2020Clinical Otolaryngology14 citations
Semantic Scholar
Systematic review of patients’ and healthcare professionals’ views on patient‐initiated follow‐up in treated cancer patients
J. Dretzke, A. Lorenc, Ada Adriano, Clare P. Herd +24 more
2023Cancer Medicine13 citations Open access
Semantic Scholar
Human papilloma virus detection in oropharyngeal carcinomas with in situ hybridisation using hand crafted morphological features and deep central attention residual networks
Shereen Fouad, G. Landini, M. Robinson, Tzu-Hsi Song +1 more
2021Comput. Medical Imaging Graph.13 citations Open access
Semantic Scholar
Comparison of different guidelines for oral cancer
H. F. Köhler, H. Mehanna, J. Shah, Á. Sanabria +6 more
2020European Archives of Oto-Rhino-Laryngology12 citations Open access
Semantic Scholar
Routine restaging after primary non-surgical treatment of laryngeal squamous cell carcinoma—a review
C. Seebauer, B. Hackenberg, J. Grosse, J. Rennert +7 more
2020Strahlentherapie und Onkologie (Print)12 citations Open access
Semantic Scholar
A multicenter randomized trial for quality of life evaluation by non-invasive intelligent tools during post-curative treatment follow-up for head and neck cancer: Clinical study protocol
S. Cavalieri, C. Vener, Marissa LeBlanc, L. López-Pérez +19 more
2023Frontiers in Oncology11 citations Open access
Semantic Scholar
Circulating Tumour Cell Expression of Immune Markers as Prognostic and Therapeutic Biomarkers in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis
K. Payne, M. Pugh, J. Brooks, N. Batis +3 more
2020International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Ultra-Low DNA Input into Whole Genome Methylation Assays and Detection of Oncogenic Methylation and Copy Number Variants in Circulating Tumour DNA
C. Whalley, K. Payne, E. Domingo, A. Blake +7 more
2021Epigenomes10 citations Open access
Semantic Scholar
Improvement in Dysphagia Outcomes Following Clinical Target Volume Reduction in the De-ESCALaTE Study.
M. Vreugdenhil, C. Fong, G. Iqbal, T. Roques +14 more
2021Clinics in oncology10 citations Open access
Semantic Scholar

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