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J. Zabkiewicz · SciRah

Researcher profile · Semantic Scholar

J. Zabkiewicz

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J. Zabkiewicz — researcher profile on SciRah

h-index: 10
Works: 24
Citations: 771

Most-cited papers

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling.
P. Hole, J. Zabkiewicz, C. Munje, Z. Newton +7 more
2013Blood234 citations Open access
Semantic Scholar
Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
G. Dolton, C. Rius, A. Wall, Barbara Szomolay +29 more
2023Cell138 citations Open access
Semantic Scholar
MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine
O. Sansom, J. Zabkiewicz, S. M. Bishop, J. Guy +2 more
2003Oncogene102 citations Open access
Semantic Scholar
Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine
B. Shorning, J. Zabkiewicz, Afshan Mccarthy, Helen B Pearson +4 more
2009PLoS ONE69 citations Open access
Semantic Scholar
The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts
J. Zabkiewicz, L. Pearn, R. Hills, R. Morgan +3 more
2014Haematologica54 citations Open access
Semantic Scholar
Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors.
L. Chilukamarri, Anne L. Hancock, Sally Malik, J. Zabkiewicz +7 more
2007Neoplasia50 citations Open access
Semantic Scholar
DNA damage-induced apoptosis: insights from the mouse.
J. Zabkiewicz, A. Clarke
2004Biochimica et Biophysica Acta33 citations
Semantic Scholar
Characterization of synthetic and commercial trisiloxane surfactant materials
L. Bonnington, W. Henderson, J. Zabkiewicz
200429 citations
Semantic Scholar
Tinkering under the Hood: Metabolic Optimisation of CAR-T Cell Therapy
Yasmin R. Jenkins, J. Zabkiewicz, O. Ottmann, Nicholas Jones
2021Antibodies21 citations Open access
Semantic Scholar
The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias
J. Zabkiewicz, M. Gilmour, R. Hills, P. Vyas +4 more
2016OncoTarget10 citations Open access
Semantic Scholar
Tris(8-hydroxyquinolinato)gallium(III)-loaded copolymer micelles as cytotoxic nanoconstructs for cosolvent-free organometallic drug delivery.
A. Collins, J. Zabkiewicz, Chiara Ghiggi, Jonathan Hauser +2 more
2011Small5 citations
Semantic Scholar
Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine
B. Shorning, J. Zabkiewicz, Afshan Mccarthy, Helen B Pearson +4 more
2009PLoS ONE5 citations Open access
Semantic Scholar
Results of a Phase 2 Trial of the Monocyte-Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) in Chronic Myelomonocytic Leukemia (CMML) — the UK Monocle Study
S. Knapper, M. Dennis, M. Drummond, R. Hills +12 more
2018Blood4 citations
Semantic Scholar
Axl/ Mer Inhibitor ONO-9330547 As a Novel Therapeutic Agent in a Stromal Co-Culture Model of Primary Acute Myeloid Leukaemia (AML)
M. Gilmour, A. Scholtz, O. Ottmann, R. Hills +2 more
20164 citations
Semantic Scholar
Combination of a mitogen‐activated protein kinase inhibitor with the tyrosine kinase inhibitor pacritinib combats cell adhesion‐based residual disease and prevents re‐expansion of FLT3‐ITD acute myeloid leukaemia
J. Zabkiewicz, M. Lazenby, G. Edwards, C. Bygrave +7 more
2020British Journal of Haematology3 citations Open access
Semantic Scholar
Adipogeneis in the Bone Marrow Microenvironment Confers a Proliferative Advantage in Residual Leukaemic Cell Populations in Acute Myeloid Leukaemia after Allogeneic Stem Cell Transplantation
Felicity May, Caroline Alvares, O. Ottmann, J. Zabkiewicz
2018Blood3 citations Open access
Semantic Scholar
Pacritinib Suppresses Leukemic Outgrowth from FLT3-ITD Positive Stroma-Adherent Primary AML Cells
C. Marrin, G. Edwards, S. Knapper, A. Burnett +2 more
20143 citations
Semantic Scholar
Extracellular Microvesicle Cytokines Secreted from Bone Marrow Mesenchymal Cells Mediate Proliferative and Survival Advantage in Acute Myeloid Leukaemia
M. Lazenby, O. Ottmann, K. WIlson, Caroline Alvares +1 more
2018Blood2 citations Open access
Semantic Scholar
Bone Marrow Stromal Cells Mediate Adhesion Based Drug Resistance in Acute Myeloid Leukaemia through Reciprocal Feedback of the β-Catenin/CD44 Signalling Axis
Lihui Zhuang, R. Darley, O. Ottmann, J. Zabkiewicz +1 more
2018Blood1 citations
Semantic Scholar
The Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) Shows Selective In Vitro Efficacy In Monocytoid-Lineage Acute Myeloid Leukaemia (AML)
J. Zabkiewicz, R. Hills, E. Bone, A. Davidson +2 more
20131 citations
Semantic Scholar
Investigating KAT2A protac therapy for targeting leukemic blast differentiation in acute myeloid leukaemia.
A. Zerdelis, Claudia Chriches, Loren Waters, L. Sadeghi +4 more
2025Blood0 citations
Semantic Scholar
Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine
B. Shorning, J. Zabkiewicz, Afshan Mccarthy, Helen B Pearson +4 more
2019PLoS ONE0 citations Open access
Semantic Scholar
PDK1 Overexpression In Acute Myeloid Leukemia; Clinical Significance and Potential as a Therapeutic Target
J. Zabkiewicz, L. Pearn, R. Hills, R. Morgan +3 more
20100 citations
Semantic Scholar
In vivo modelling of tumour suppressor gene function
J. Zabkiewicz
20050 citations
Semantic Scholar

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