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F. Alén · SciRah

Researcher profile · Semantic Scholar

F. Alén

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F. Alén — researcher profile on SciRah

h-index: 22
Works: 59
Citations: 1,410

Most-cited papers

Oleoylethanolamide prevents neuroimmune HMGB1/TLR4/NF‐kB danger signaling in rat frontal cortex and depressive‐like behavior induced by ethanol binge administration
María Antón, F. Alén, Raquel Gómez de Heras, A. Serrano +5 more
2017Addiction Biology110 citations
Semantic Scholar
Systemic Administration of Oleoylethanolamide Protects from Neuroinflammation and Anhedonia Induced by LPS in Rats
A. Sayd, María Antón, F. Alén, J. Caso +5 more
2015International Journal of Neuropsychopharmacology102 citations Open access
Semantic Scholar
Oleoylethanolamide, Neuroinflammation, and Alcohol Abuse
L. Orio, F. Alén, F. Pavón, A. Serrano +1 more
2019Frontiers in Molecular Neuroscience90 citations Open access
Semantic Scholar
A neuropsychological assessment of frontal cognitive functions in Prader-Willi syndrome.
J. Jauregi, C. Arias, O. Vegas, F. Alén +3 more
2007Journal of Intellectual Disability Research88 citations
Semantic Scholar
Role for the satiety factor Oleoylethanolamide in alcoholism
A. Bilbao, A. Serrano, A. Cippitelli, F. Pavón +12 more
2015Addiction Biology64 citations Open access
Semantic Scholar
Alcohol‐induced cognitive deficits are associated with decreased circulating levels of the neurotrophin BDNF in humans and rats
Daniel Silva-Peña, N. García-Marchena, F. Alén, P. Araos +12 more
2018Addiction Biology63 citations
Semantic Scholar
Plasma concentrations of oleoylethanolamide in a primary care sample of depressed patients are increased in those treated with selective serotonin reuptake inhibitor‐type antidepressants
P. Romero-Sanchiz, R. Nogueira-Arjona, A. Pastor, P. Araos +10 more
2019Neuropharmacology46 citations Open access
Semantic Scholar
Cocaine-Induced Behavioral Sensitization Is Associated With Changes in the Expression of Endocannabinoid and Glutamatergic Signaling Systems in the Mouse Prefrontal Cortex
E. Blanco, F. Pavón, A. Palomino, M. Luque-Rojas +7 more
2014International Journal of Neuropsychopharmacology43 citations Open access
Semantic Scholar
Adaptive Stress Coping in Awake Bruxism
Xabier A Soto-Goñi, F. Alén, Leticia Buiza-González, Danielle Marcolino-Cruz +4 more
2020Frontiers in Neurology42 citations Open access
Semantic Scholar
Exposure to a Highly Caloric Palatable Diet During Pregestational and Gestational Periods Affects Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Adiposity and Anxiety-Like Behaviors in Male Rat Offspring
M. Ramírez-López, M. Vázquez, L. Bindila, Ermelinda Lomazzo +11 more
2016Frontiers in Behavioral Neuroscience40 citations Open access
Semantic Scholar
Maternal Caloric Restriction Implemented during the Preconceptional and Pregnancy Period Alters Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Overweight and Increased Adiposity at Adulthood in Male Rat Offspring
M. Ramírez-López, M. Vázquez, L. Bindila, Ermelinda Lomazzo +12 more
2016Frontiers in Behavioral Neuroscience39 citations Open access
Semantic Scholar
Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.
Keiko Horiuchi, S. Pérez-Cerezales, Panagiotis K. Papasaikas, P. Ramos-Ibeas +15 more
2018Cell Reports37 citations Open access
Semantic Scholar
A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity.
Javier García-Cárceles, J. Decara, Henar Vázquez-Villa, Ramón Rodríguez +11 more
2017Journal of Medicinal Chemistry36 citations Open access
Semantic Scholar
Cannabinoid-induced increase in relapse-like drinking is prevented by the blockade of the glycine-binding site of N-methyl-D-aspartate receptors.
F. Alén, Angel Santos, G. Moreno-Sanz, G. González-Cuevas +4 more
2009Neuroscience36 citations
Semantic Scholar
Ghrelin-Induced Orexigenic Effect in Rats Depends on the Metabolic Status and Is Counteracted by Peripheral CB1 Receptor Antagonism
F. Alén, I. Crespo, M. Ramírez-López, N. Jagerovic +4 more
2013PLoS ONE34 citations Open access
Semantic Scholar
Pharmacological activation of CB1 and D2 receptors in rats: predominant role of CB1 in the increase of alcohol relapse
F. Alén, G. Moreno-Sanz, Ana Isabel de Tena, Rayna D. Brooks +3 more
2008European Journal of Neuroscience30 citations
Semantic Scholar
Oleoylethanolamide Modulates BDNF-ERK Signaling and Neurogenesis in the Hippocampi of Rats Exposed to Δ9-THC and Ethanol Binge Drinking During Adolescence
Daniel Silva-Peña, P. Rivera, F. Alén, A. Vargas +6 more
2019Frontiers in Molecular Neuroscience29 citations Open access
Semantic Scholar
Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat Offspring
M. Ramírez-López, R. Arco, J. Decara, M. Vázquez +5 more
2016PLoS ONE29 citations Open access
Semantic Scholar
Effects of acute versus repeated cocaine exposure on the expression of endocannabinoid signaling-related proteins in the mouse cerebellum
A. Palomino, F. Pavón, Eduardo Blanco-Calvo, A. Serrano +8 more
2014Frontiers in Integrative Neuroscience27 citations Open access
Semantic Scholar
Increased plasma oleoylethanolamide and palmitoleoylethanolamide levels correlate with inflammatory changes in alcohol binge drinkers: the case of HMGB1 in women
María Antón, A. Rodríguez-González, Inmaculada Concepción Rodríguez-Rojo, A. Pastor +8 more
2018Addiction Biology26 citations
Semantic Scholar
Involvement of the ghrelin system in the maintenance and reinstatement of cocaine-motivated behaviors: a role of adrenergic action at peripheral β1 receptors
Zhi-Bing You, E. Galaj, F. Alén, Bin Wang +9 more
2021Neuropsychopharmacology25 citations Open access
Semantic Scholar
Antianhedonic and Antidepressant Effects of Affron®, a Standardized Saffron (Crocus Sativus L.) Extract
L. Orio, F. Alén, A. Ballesta, Raquel Martín +1 more
2020Molecules23 citations Open access
Semantic Scholar
Systemic blockade of LPA1/3 lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior
L. Sánchez-Marín, David Ladrón de Guevara-Miranda, Carmen M. Mañas‐Padilla, F. Alén +10 more
2018Neuropharmacology22 citations Open access
Semantic Scholar
Long-Term Effects of Prenatal Exposure to Undernutrition on Cannabinoid Receptor-Related Behaviors: Sex and Tissue-Specific Alterations in the mRNA Expression of Cannabinoid Receptors and Lipid Metabolic Regulators
M. Ramírez-López, Rocío Arco, J. Decara, M. Vázquez +6 more
2016Frontiers in Behavioral Neuroscience21 citations Open access
Semantic Scholar
Increased alcohol consumption in rats after subchronic antidepressant treatment.
F. Alén, L. Orio, M. A. Gorriti, R. G. de Heras +3 more
2013International Journal of Neuropsychopharmacology21 citations Open access
Semantic Scholar
Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration.
C. Reyes-Cabello, F. Alén, R. Gómez, A. Serrano +4 more
2012Pharmacology, Biochemistry and Behavior21 citations Open access
Semantic Scholar
Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for “Diabesity”
J. Decara, Henar Vázquez-Villa, J. Bréa, M. Alonso +18 more
2022Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
A moderate diet restriction during pregnancy alters the levels of endocannabinoids and endocannabinoid-related lipids in the hypothalamus, hippocampus and olfactory bulb of rat offspring in a sex-specific manner
M. Ramírez-López, M. Vázquez, Ermelinda Lomazzo, Clementine Hofmann +11 more
2017PLoS ONE19 citations Open access
Semantic Scholar
Role of the galanin N-terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system
Carmelo Millón, A. Flores-Burgess, B. Gago, F. Alén +6 more
2019Journal of Psychopharmacology16 citations Open access
Semantic Scholar
Preparation, characterization and in vivo evaluation of nanoemulsions for the controlled delivery of the antiobesity agent N-oleoylethanolamine.
Miguel Wulff-Pérez, F. Pavón, A. Martín-Rodríguez, J. de Vicente +4 more
2014Nanomedicine16 citations
Semantic Scholar
Effects of Synchronous and Asynchronous Embryo Transfer on Postnatal Development, Adult Health, and Behavior in Mice1
A. López-Cardona, R. Fernández-González, M. Pérez-Crespo, F. Alén +3 more
2015Biology of Reproduction15 citations Open access
Semantic Scholar
Cerebellar and cortical TLR4 activation and behavioral impairments in Wernicke-Korsakoff Syndrome: Pharmacological effects of oleoylethanolamide.
M. Moya, D. Felipe, A. Ballesta, F. Alén +4 more
2020Progress in Neuro-psychopharmacology and Biological Psychiatry14 citations
Semantic Scholar
Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala
J. Suárez, S. Khom, F. Alén, Luis A. Natividad +10 more
2019Addiction Biology14 citations Open access
Semantic Scholar
PPAR&agr;/CB1 receptor dual ligands as a novel therapy for alcohol use disorder: Evaluation of a novel oleic acid conjugate in preclinical rat models
F. Alén, J. Decara, Gloria Brunori, Zhi-Bing You +10 more
2018Biochemical Pharmacology14 citations
Semantic Scholar
Effects of Adolescent Intermittent Alcohol Exposure on the Expression of Endocannabinoid Signaling-Related Proteins in the Spleen of Young Adult Rats
F. Pavón, E. Marco, M. Vázquez, Laura Sánchez +12 more
2016PLoS ONE14 citations Open access
Semantic Scholar
Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain
P. Rivera, E. Blanco, L. Bindila, F. Alén +7 more
2015Frontiers in Cellular Neuroscience14 citations Open access
Semantic Scholar
Sex-Dimorphic Behavioral Alterations and Altered Neurogenesis in U12 Intron Splicing-Defective Zrsr1 Mutant Mice
F. Alén, I. Gómez-Redondo, P. Rivera, J. Suárez +8 more
2019International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
Cannabinoid receptors and cholecystokinin in feeding inhibition.
F. Alén, M. Ramírez-López, Raquel Gómez de Heras, F. Rodríguez de Fonseca +1 more
2013Vitamins and hormones12 citations
Semantic Scholar
Nicotine causes opposite effects on alcohol intake: Evidence in an animal experimental model of abstinence and relapse from alcohol.
F. Alén, R. Gómez, G. González-Cuevas, M. Navarro +1 more
2009Nicotine & Tobacco Research12 citations
Semantic Scholar
Hyperplastic Obesity and Liver Steatosis as Long-Term Consequences of Suboptimal In Vitro Culture of Mouse Embryos1
A. Serrano, J. Decara, R. Fernández-González, A. López-Cardona +5 more
2014Biology of Reproduction11 citations Open access
Semantic Scholar
Converging action of alcohol consumption and cannabinoid receptor activation on adult hippocampal neurogenesis.
F. Alén, A. Mouret, Maria-Paz Viveros, R. Llorente +3 more
2010International Journal of Neuropsychopharmacology11 citations Open access
Semantic Scholar
concentrations of
N. Pavón, U. A. Boronat, P. Romero-Sanchiz, R. Nogueira-Arjona +9 more
11 citations
Semantic Scholar
The administration of atomoxetine during alcohol deprivation induces a time-limited increase in alcohol consumption after relapse.
F. Alén, A. Serrano, M. A. Gorriti, F. Pavón +6 more
2014International Journal of Neuropsychopharmacology9 citations Open access
Semantic Scholar
Pharmacological activation of CB 2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain
P. Rivera, E. Blanco, L. Bindila, F. Alén +7 more
20158 citations
Semantic Scholar
Sudden cessation of fluoxetine before alcohol drinking reinstatement alters microglial morphology and TLR4/inflammatory neuroadaptation in the rat brain
J. Aranda, M. Fernández-Arjona, F. Alén, P. Rivera +7 more
2021Brain Structure and Function6 citations Open access
Semantic Scholar
Bupropion, a possible antidepressant without negative effects on alcohol relapse.
A. Ballesta, L. Orio, Rocío Arco, A. Vargas +10 more
2019European Neuropsychopharmacology5 citations Open access
Semantic Scholar
Abrupt cessation of reboxetine along alcohol deprivation results in alcohol intake escalation after reinstatement of drinking
A. Ballesta, F. Alén, L. Orio, Rocío Arco +9 more
2020Addiction Biology4 citations Open access
Semantic Scholar
Gestational saccharin consumption disrupts gut-brain axis glucose homeostasis control in adolescent offspring rats in a sex-dependent manner
Beatriz Pacheco-Sánchez, S. Melgar-Locatelli, Raquel López-Merchán, María José Benítez-Marín +10 more
2025Biology of Sex Differences3 citations Open access
Semantic Scholar
Sex‐specific behavioral and neurogenic responses to cocaine in mice lacking and blocking dopamine D1 or dopamine D2 receptors
P. Rivera, J. Aranda, F. Alén, A. Vargas +7 more
2020The Journal of comparative neurology2 citations Open access
Semantic Scholar
ADDITIONS AND CORRECTIONS. Effects of Synchronous and Asynchronous Embryo Transfer on Postnatal Development, Adult Health, and Behavior in Mice.
A. López-Cardona, R. Fernández-González, M. Pérez-Crespo, F. Alén +3 more
2016Biology of Reproduction2 citations
Semantic Scholar

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F. D. de Fonseca×11

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