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Yasushi Hirota · SciRah

Researcher profile · Semantic Scholar

Yasushi Hirota

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Yasushi Hirota — researcher profile on SciRah

h-index: 53
Works: 285
Citations: 8,783

Most-cited papers

Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M
Hajime Abe, N. Takeda, T. Isagawa, H. Semba +21 more
2019Nature Communications127 citations Open access
Semantic Scholar
Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations
Satoshi Inoue, Yasushi Hirota, T. Ueno, Yamato Fukui +20 more
2019Nature Communications114 citations Open access
Semantic Scholar
Uterine receptivity, embryo attachment, and embryo invasion: Multistep processes in embryo implantation
Yamato Fukui, Yasushi Hirota, Mitsunori Matsuo, Mona Gebril +3 more
2019Reproductive Medicine and Biology96 citations Open access
Semantic Scholar
Automated system for diagnosing endometrial cancer by adopting deep-learning technology in hysteroscopy
Yu Takahashi, Kenbun Sone, Katsuhiko Noda, Kaname Yoshida +18 more
2021PLoS ONE80 citations Open access
Semantic Scholar
Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS.
J. Azhary, M. Harada, Nozomi Takahashi, Emi Nose +8 more
2018Endocrinology74 citations
Semantic Scholar
HIF2&agr; in the uterine stroma permits embryo invasion and luminal epithelium detachment
L. Matsumoto, Yasushi Hirota, Tomoko Saito-Fujita, N. Takeda +11 more
2018Journal of Clinical Investigation70 citations Open access
Semantic Scholar
Endometriosis triggers excessive activation of primordial follicles via PI3K-PTEN-Akt-Foxo3 pathway.
Arisa Takeuchi, K. Koga, E. Satake, T. Makabe +10 more
2019Journal of Clinical Endocrinology and Metabolism64 citations
Semantic Scholar
Activation of Nrf2 might reduce oxidative stress in human granulosa cells.
Nana Akino, Osamu Wada-Hiraike, Hiromi Terao, Harunori Honjoh +13 more
2017Molecular and Cellular Endocrinology63 citations
Semantic Scholar
CD206+ M2-Like Macrophages Are Essential for Successful Implantation
Yosuke Ono, O. Yoshino, Takehiro Hiraoka, Erina Sato +9 more
2020Frontiers in Immunology62 citations Open access
Semantic Scholar
Androgens increase accumulation of advanced glycation end products in granulosa cells by activating ER stress in PCOS.
J. Azhary, M. Harada, C. Kunitomi, A. Kusamoto +10 more
2020Endocrinology61 citations Open access
Semantic Scholar
Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary
Nana Akino, Osamu Wada-Hiraike, Wataru Isono, Hiromi Terao +12 more
2019Reproductive Biology and Endocrinology51 citations Open access
Semantic Scholar
CD206+ macrophage is an accelerator of endometriotic-like lesion via promoting angiogenesis in the endometriosis mouse model
Yosuke Ono, O. Yoshino, Takehiro Hiraoka, Erina Sato +10 more
2021Scientific Reports47 citations Open access
Semantic Scholar
Endothelial Cells in the Decidual Bed Are Potential Therapeutic Targets for Preterm Birth Prevention
Wenbo Deng, Jia Yuan, J. Cha, Xiao-Fei Sun +4 more
2019Cell Reports45 citations Open access
Semantic Scholar
Progesterone governs endometrial proliferation-differentiation switching and blastocyst implantation.
Yasushi Hirota
2019Endocrine journal44 citations Open access
Semantic Scholar
Activation of endoplasmic reticulum stress mediates oxidative stress-induced apoptosis of granulosa cells in ovaries affected by endometrioma.
C. Kunitomi, M. Harada, Nozomi Takahashi, J. M. Azhary +10 more
2019Molecular human reproduction43 citations
Semantic Scholar
Mannose receptor is highly expressed by peritoneal dendritic cells in endometriosis.
G. Izumi, K. Koga, M. Takamura, T. Makabe +7 more
2017Fertility and Sterility43 citations
Semantic Scholar
Accumulation of advanced glycation end products in follicles is associated with poor oocyte developmental competence.
Nozomi Takahashi, M. Harada, J. Azhary, C. Kunitomi +9 more
2019Molecular human reproduction39 citations
Semantic Scholar
Differential roles of uterine epithelial and stromal STAT3 coordinate uterine receptivity and embryo attachment
Takehiro Hiraoka, Yasushi Hirota, Yamato Fukui, Mona Gebril +12 more
2020Scientific Reports38 citations Open access
Semantic Scholar
Mdm2‐p53‐SF1 pathway in ovarian granulosa cells directs ovulation and fertilization by conditioning oocyte quality
Hirofumi Haraguchi, Yasushi Hirota, Tomoko Saito-Fujita, Tomoki Tanaka +11 more
2018The FASEB Journal38 citations Open access
Semantic Scholar
Oil-Soluble Contrast Medium (OSCM) for Hysterosalpingography Modulates Dendritic Cell and Regulatory T Cell Profiles in the Peritoneal Cavity: A Possible Mechanism by Which OSCM Enhances Fertility
G. Izumi, K. Koga, M. Takamura, Wang Bo +8 more
2017Journal of Immunology38 citations Open access
Semantic Scholar
Thoracic endometriosis syndrome: Comparison between catamenial pneumothorax or endometriosis-related pneumothorax and catamenial hemoptysis.
Shinya Fukuda, T. Hirata, Kazuaki Neriishi, Akari Nakazawa +8 more
2018European Journal of Obstetrics, Gynecology, and Reproductive Biology37 citations
Semantic Scholar
The EZH2–PRC2–H3K27me3 axis governs the endometrial cell cycle and differentiation for blastocyst invasion
Yamato Fukui, Yasushi Hirota, S. Aikawa, A. Sakashita +10 more
2023Cell Death and Disease33 citations Open access
Semantic Scholar
Uterine epithelial progesterone receptor governs uterine receptivity through epithelial cell differentiation.
Mona Gebril, Yasushi Hirota, S. Aikawa, Yamato Fukui +12 more
2020Endocrinology32 citations Open access
Semantic Scholar
Niclosamide suppresses macrophage-induced inflammation in endometriosis†
Nikola Sekulovski, Allison E. Whorton, Tomoki Tanaka, Yasushi Hirota +7 more
2020Biology of Reproduction31 citations Open access
Semantic Scholar
The Role of Cellular Senescence in Cyclophosphamide-Induced Primary Ovarian Insufficiency
Zi-Xin Xu, Nozomi Takahashi, M. Harada, C. Kunitomi +8 more
2023International Journal of Molecular Sciences29 citations Open access
Semantic Scholar
Preoperative assessment of factors associated with difficulty in performing total laparoscopic hysterectomy
Ako Saito, T. Hirata, K. Koga, M. Takamura +8 more
2017The journal of obstetrics and gynaecology research29 citations
Semantic Scholar
Current perspectives on endometrial receptivity: A comprehensive overview of etiology and treatment
Takehiro Hiraoka, Y. Osuga, Yasushi Hirota
2023The journal of obstetrics and gynaecology research28 citations Open access
Semantic Scholar
Induction of aryl hydrocarbon receptor in granulosa cells by endoplasmic reticulum stress contributes to pathology of polycystic ovary syndrome.
C. Kunitomi, M. Harada, A. Kusamoto, J. M. Azhary +10 more
2021Molecular human reproduction28 citations
Semantic Scholar
Uterine epithelial LIF receptors contribute to implantation chamber formation in blastocyst attachment.
Yamato Fukui, Yasushi Hirota, Tomoko Saito-Fujita, S. Aikawa +9 more
2021Endocrinology25 citations Open access
Semantic Scholar
Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion
Shun Akaeda, Yasushi Hirota, Yamato Fukui, S. Aikawa +11 more
2021EMBO Reports24 citations Open access
Semantic Scholar
Levonorgestrel inhibits embryo attachment by eliminating uterine induction of leukemia inhibitory factor.
Mitsunori Matsuo, Yasushi Hirota, Yamato Fukui, Hidetoshi Fujita +13 more
2020Endocrinology23 citations
Semantic Scholar
Clinical aspects and management of inguinal endometriosis: A case series of 20 patients
Tomoko Arakawa, T. Hirata, K. Koga, Kazuaki Neriishi +9 more
2019The journal of obstetrics and gynaecology research22 citations
Semantic Scholar
A survey of public attitudes toward uterus transplantation, surrogacy, and adoption in Japan
Akari Nakazawa, T. Hirata, Tomoko Arakawa, Natsuki Nagashima +10 more
2019PLoS ONE22 citations Open access
Semantic Scholar
Notch Signaling Induced by Endoplasmic Reticulum Stress Regulates Cumulus-Oocyte Complex Expansion in Polycystic Ovary Syndrome
Hiroshi Koike, M. Harada, A. Kusamoto, C. Kunitomi +9 more
2022Biomolecules21 citations Open access
Semantic Scholar
IFITM1 is a Novel, Highly Sensitive Marker for Endometriotic Stromal Cells in Ovarian and Extragenital Endometriosis
Hui Sun, Shinya Fukuda, T. Hirata, Tomoko Arakawa +13 more
2019Reproductive Sciences21 citations Open access
Semantic Scholar
Pharmacology of Parsabiv® (etelcalcetide, ONO‐5163/AMG 416), a novel allosteric modulator of the calcium‐sensing receptor, for secondary hyperparathyroidism in hemodialysis patients
Kazutsune Harada, A. Fujioka, M. Konno, Atsuto Inoue +2 more
2019European Journal of Pharmacology20 citations Open access
Semantic Scholar
A gene network of uterine luminal epithelium organizes mouse blastocyst implantation
S. Aikawa, Yasushi Hirota, Yamato Fukui, Chihiro Ishizawa +7 more
2022Reproductive Medicine and Biology19 citations Open access
Semantic Scholar
Expression of ALDH1A Isozymes in Human Endometrium with and without Endometriosis and in Ovarian Endometrioma
Suke Ma, T. Hirata, Tomoko Arakawa, Hui Sun +10 more
2020Reproductive Sciences19 citations
Semantic Scholar
Role of oxidative stress in follicular fluid on embryos of patients undergoing assisted reproductive technology treatment
Hiromi Terao, Osamu Wada-Hiraike, Aiko Nagumo, C. Kunitomi +7 more
2019The journal of obstetrics and gynaecology research19 citations
Semantic Scholar
Differences in the incidence of obstetric complications depending on the extent and location of adenomyosis lesions
A. Hashimoto, Takayuki Iriyama, S. Sayama, Asuka Okamura +9 more
2023Journal of Maternal-Fetal & Neonatal Medicine16 citations Open access
Semantic Scholar
Levonorgestrel-Releasing Intrauterine System Improves Menorrhagia-Related Quality of Life in Patients with Symptomatic Adenomyosis
Chihiro Ishizawa, Yasushi Hirota, Rei Iida, Tetsuaki Kaku +7 more
2022Reproductive Sciences16 citations
Semantic Scholar
Constant activation of STAT3 contributes to the development of adenomyosis in females.
Takehiro Hiraoka, Yasushi Hirota, S. Aikawa, Rei Iida +9 more
2022Endocrinology16 citations Open access
Semantic Scholar
Acquired contractile ability in human endometrial stromal cells by passive loading of cyclic tensile stretch
Jeonghyun Kim, T. Ushida, K. Montagne, Yasushi Hirota +4 more
2020Scientific Reports16 citations Open access
Semantic Scholar
Use of selective PGE2 receptor antagonists on human endometriotic stromal cells and peritoneal macrophages
T. Makabe, K. Koga, Hiroshi Nagabukuro, Mari Asada +10 more
2020Molecular human reproduction16 citations Open access
Semantic Scholar
PAX8: A Highly Sensitive Marker for the Glands in Extragenital Endometriosis.
Tomoko Arakawa, Shinya Fukuda, T. Hirata, Kazuaki Neriishi +11 more
2019Reproductive Sciences16 citations Open access
Semantic Scholar
Uterine Receptivity is Reflected by LIF Expression in the Cervix
Yamato Fukui, Yasushi Hirota, S. Aikawa, Chihiro Ishizawa +7 more
2021Reproductive Sciences15 citations
Semantic Scholar
Guidelines for Reproductive Medicine in Japan
Mitsutoshi Yamada, T. Ishikawa, T. Iwasa, H. Oishi +41 more
2022Reproductive Medicine and Biology14 citations Open access
Semantic Scholar
How does adenomyosis impact endometrial receptivity? An updated systematic review of clinical and molecular insights
Takehiro Hiraoka, Yasushi Hirota, Y. Osuga
2022F&S Reviews14 citations Open access
Semantic Scholar
PAX8: A Highly Sensitive Marker for the Glands in Extragenital Endometriosis
Tomoko Arakawa, Shinya Fukuda, T. Hirata, Kazuaki Neriishi +11 more
2020Reproductive Sciences14 citations
Semantic Scholar
The effects of tokishakuyakusan, a traditional Japanese medicine (kampo), ferulic acid and paeoniflorin, on human endometriotic stromal cells and peritoneal macrophages.
Arisa Takeuchi, K. Koga, Yohei Tokita, Takashi Matsumoto +11 more
2020Journal of Reproductive Immunology14 citations
Semantic Scholar

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