Atsuto Inoue

Most-cited papers

1. Using zebrafish in systems toxicology for developmental toxicity testing

   Yuhei Nishimura, Atsuto Inoue, Shota Sasagawa, J. Koiwa +5 more

   2016Congenital Anomalies181 citations Open access

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2. Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma.

   Satoshi Itadani, Kentaro Yashiro, Yoshiyuki Aratani, Tetsuya Sekiguchi +25 more

   2015Journal of Medicinal Chemistry21 citations Open access

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3. Pharmacology of Parsabiv® (etelcalcetide, ONO‐5163/AMG 416), a novel allosteric modulator of the calcium‐sensing receptor, for secondary hyperparathyroidism in hemodialysis patients

   Kazutsune Harada, A. Fujioka, M. Konno, Atsuto Inoue +2 more

   2019European Journal of Pharmacology20 citations Open access

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4. Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs

   Atsuto Inoue, Yuhei Nishimura, Norihito Matsumoto, Noriko Umemoto +9 more

   201620 citations Open access

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5. Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a guinea pig model of asthma.

   Y. Yonetomi, Tomohiko Sekioka, M. Kadode, T. Kitamine +10 more

   2015European Journal of Pharmacology18 citations

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6. The pharmacological profile and the clinical efficacy of the world's 1st intravenous calcimimetics; etelcalcetide hydrochloride (Parsabiv®).

   Kazutsune Harada, Atsuto Inoue, Akinori Yamauchi, Akifumi Fujii

   2017Nihon yakurigaku zasshi. Folia pharmacologica Japonica8 citations Open access

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7. Discovery of a potent, orally available dual CysLT₁ and CysLT₂ antagonist with dicarboxylic acid.

   Satoshi Itadani, S. Takahashi, Masaki Ima, Tetsuya Sekiguchi +8 more

   2015Bioorganic & Medicinal Chemistry6 citations Open access

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8. [The Discovery, Research and Development of Etelcalcetide Hydrochloride, the World 1st Intravenous Calcimimetics.]

   Atsuto Inoue, Kazutsune Harada

   2017Clinical calcium4 citations

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9. Etelcalcetide decreases the PTH–calcium setpoint without changing maximum and minimum PTH secretion in mice with primary hyperparathyroidism

   Noriyuki Hayashi, Y. Imanishi, T. Hirakawa, Ikue Kobayashi +9 more

   2020Journal of Bone and Mineral Metabolism1 citations

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10. Effect of etelcalcetide on parathyroid hormone secretion by primary hyperparathyroidism patient-derived primary parathyroid cells

    A. Fujioka, Y. Imanishi, Ikue Kobayashi, T. Hirakawa +9 more

    2020Journal of Bone and Mineral Metabolism1 citations

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11. FP031ETELCALCETIDE (PARSABIV®, AMG 416/ONO-5163) DIRECTLY REDUCED PARATHYROID HORMONE LEVELS IN HUMAN PARATHYROID CELL CULTURE

    Atsuto Inoue, A. Fujioka, Kazutsune Harada, M. Taguchi +5 more

    2019Nephrology, Dialysis and Transplantation0 citations

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