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Giulia Schiroli · SciRah

Researcher profile · Semantic Scholar

Giulia Schiroli

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Giulia Schiroli — researcher profile on SciRah

h-index: 10
Works: 40
Citations: 1,548

Most-cited papers

Targeted Genome Editing in Human Repopulating Hematopoietic Stem Cells
P. Genovese, Giulia Schiroli, Giulia Escobar, T. Di Tomaso +12 more
2014Nature564 citations Open access
Semantic Scholar
Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response
Giulia Schiroli, Anastasia Conti, S. Ferrari, Lucrezia della Volpe +15 more
2019Cell Stem Cell309 citations Open access
Semantic Scholar
Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1
Giulia Schiroli, S. Ferrari, Anthony Conway, Aurélien Jacob +15 more
2017Science Translational Medicine198 citations Open access
Semantic Scholar
Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells
C. Petrillo, Lucy G. Thorne, G. Unali, Giulia Schiroli +12 more
2018Cell Stem Cell101 citations Open access
Semantic Scholar
Sleep exerts lasting effects on hematopoietic stem cell function and diversity
C. McAlpine, Máté G. Kiss, F. Zuraikat, David Cheek +19 more
2022Journal of Experimental Medicine75 citations Open access
Semantic Scholar
NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.
S. Mastaglio, P. Genovese, Z. Magnani, E. Ruggiero +21 more
2017Blood74 citations Open access
Semantic Scholar
Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients
B. Díez, P. Genovese, F. Román-Rodríguez, L. Álvarez +10 more
2017EMBO Molecular Medicine58 citations Open access
Semantic Scholar
Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper‐IgM syndrome
V. Vavassori, E. Mercuri, G. Marcovecchio, M. C. Castiello +19 more
2021EMBO Molecular Medicine42 citations Open access
Semantic Scholar
Retrieval of vector integration sites from cell-free DNA
D. Cesana, A. Calabria, L. Rudilosso, P. Gallina +18 more
2021Nature Medicine38 citations Open access
Semantic Scholar
Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections
J. Elferich, Giulia Schiroli, D. Scadden, N. Grigorieff
2022bioRxiv21 citations Open access
Semantic Scholar
Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors.
Catherine Rhee, Elizabeth W. Scadden, L. Wong, Giulia Schiroli +12 more
2023Blood10 citations Open access
Semantic Scholar
Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
Giulia Schiroli, Vinay K. Kartha, Fabiana M. Duarte, Trine A. Kristiansen +8 more
2024Nature Communications9 citations Open access
Semantic Scholar
The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression
Y. Kfoury, Fei Ji, E. Jain, M. Mazzola +10 more
2023Blood Advances7 citations Open access
Semantic Scholar
Title : NY-ESO-1 TCR single edited central memory and memory stem T cells to treat multiple myeloma without inducing GvHD
S. Mastaglio, P. Genovese, Z. Magnani, E. Ruggiero +21 more
20176 citations
Semantic Scholar
In Vivo RNA delivery by targeted lipid nanoparticles enable gene editing in hematopoietic stem cells and T cells
Rahul Palchaudhuri, Michael T. Monte, Mohit Gupta, Giulia Schiroli +21 more
2025Blood5 citations
Semantic Scholar
Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
Giulia Schiroli, Vinay K. Kartha, Fabiana M. Duarte, Trine A. Kristiansen +8 more
2023bioRxiv5 citations
Semantic Scholar
In Vivo HSC Gene Editing for Correction of the Sickle Cell Mutation Using RNA Gene Writers
Lorenzo Tozzi, Giulia Schiroli, Yaser Heshmati, Yu Cao +13 more
2024Blood4 citations
Semantic Scholar
Deploying an RNA-Based Gene Writer System and Lipid Nanoparticle (LNP) Delivery to Generate Functional Chimeric Antigen Receptor (CAR) T Cells with in Vitro and In Vivo Anti-Tumor Activity
M. Magee, Alberto De Iaco, Jason Rodriguez, James B. Rottman +12 more
2023Blood4 citations Open access
Semantic Scholar
481. Targeted Genome Editing in Mouse Hematopoietic Stem/Progenitor Cells (HSPC) To Model Gene Correction of SCID-X1
Giulia Schiroli, P. Genovese, M. C. Castiello, Valentina Capo +6 more
20154 citations Open access
Semantic Scholar
Selection of human hematopoietic stem cells bearing the intended functional edit by transient AND-gate reporters.
D. Canarutto, Martina Fiumara, Vigneshwaran Venkatesan, Chiara Gaddoni +17 more
2026Nature Biotechnology3 citations Open access
Semantic Scholar
OGFOD1 enables AML chemo- and nutrient stress resistance by regulating protein synthesis
C. Mayerhofer, Dan Li, Trine A. Kristiansen, Ernst Mayerhofer +16 more
2025Cell Metabolism3 citations Open access
Semantic Scholar
In Vivo correction of the sickle cell disease mutation in hematopoietic stem cells using RNA gene writers
Yaser Heshmati, Giulia Schiroli, Lorenzo Tozzi, Michael T. Monte +17 more
2025Blood3 citations
Semantic Scholar
Delivery of Gene Writers In Vivo to Hematopoietic Stem Cells and T Cells Using Targeted and Untargeted Lipid Nanoparticles (LNP)
Michael T. Monte, Lorenzo Tozzi, Rahul Palchaudhuri, Apiwat Wangweerawong +14 more
2024Blood3 citations Open access
Semantic Scholar
245 Leveraging RNA gene writer and lipid nanoparticle delivery to engineer T cellsin vivousing all-RNA compositions
Yu Cao, Christina Ferren, Jessica Desmond, Kartika Venugopal +18 more
2024Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
Cap-Independent Protein Translation in Hematopoiesis
M. Mazzola, Ting Zhao, K. Gustafsson, Trine Kristiansen +11 more
2022Blood1 citations Open access
Semantic Scholar
Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1
Giulia Schiroli
20201 citations
Semantic Scholar
42. Correction of SCID-X1 by Targeted Genome Editing of Hematopoietic Stem/Progenitor Cells (HSPC) in the Mouse Model
Giulia Schiroli, P. Genovese, Valentina Capo, M. C. Castiello +6 more
20161 citations Open access
Semantic Scholar
Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress
Michael Mazzola, Ting Zhao, Anna Kiem, Trine A. Kristiansen +24 more
2026Science Advances0 citations Open access
Semantic Scholar
A 3D "nichoid" boost for gene-engineered blood stem cells.
Giulia Schiroli, Pietro Genovese
2026Cell Stem Cell0 citations
Semantic Scholar
Systemic delivery of phagocytosis-shielded retroviral vectors enables in vivo HSC gene therapy for sickle cell disease
Denise Klatt, Adele Mucci, Bo-Ya Liu, Marie Peschers +9 more
2026Cell Stem Cell0 citations Open access
Semantic Scholar
Differentiation stage-specific use of cap-independent and cap-dependent translation initiation in hematopoiesis
Michael Mazzola, Ting Zhao, Anna Kiem, Trine A. Kristiansen +21 more
2025bioRxiv0 citations
Semantic Scholar
Modulating mRNA Translation Fidelity As a Novel Mechanism for AML Chemoresistance
C. Mayerhofer, Dan Li, Trine A. Kristiansen, Ernst Mayerhofer +14 more
2024Blood0 citations
Semantic Scholar
In Vivo Delivery of RNA By Lipid Nanoparticles (LNP) to Hematopoietic Stem Cells and T Cells in Humanized Mice and Non-Human Primates
Michael T. Monte, Han Gu, Laura Saunders, Mohit Gupta +16 more
2023Blood0 citations Open access
Semantic Scholar
Abstract 2456: Transcriptional signatures of stem cell phenotypes in normal and clonal hematopoiesis
Ruslan Soldatov, Giulia Schiroli, P. Kharchenko, D. Scadden
2023Cancer Research0 citations
Semantic Scholar
Rigidity of Cell Fate and Function Among Monocytes
Catherine Rhee, Elizabeth W. Scadden, L. Wong, Giulia Schiroli +12 more
2021Blood0 citations Open access
Semantic Scholar
752. Single Chain TCR Gene Editing in Adoptive Cell Therapy for Multiple Myeloma
S. Mastaglio, P. Genovese, Z. Magnani, Elisa Landoni +20 more
20160 citations Open access
Semantic Scholar
558. Targeted Gene Therapy in CD34+ Cells from Healthy Donors and Fanconi Anemia Patients
B. Díez, Pietro Genovesse, Giulia Schiroli, L. Álvarez +7 more
20160 citations Open access
Semantic Scholar
37. Towards Clinical Translation of Hematopoietic Stem Cell Gene Editing for the Correction of SCID-X1 Mutations
P. Genovese, Giulia Schiroli, Anthony Conway, S. Ferrari +12 more
20160 citations Open access
Semantic Scholar
209. TCR Gene Editing in a Single Step of T Cell Activation To Redirect T Cell Specificity and Prevent GvHD
P. Genovese, S. Mastaglio, Z. Magnani, Elisa Landoni +13 more
20150 citations Open access
Semantic Scholar
NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD
S. Mastaglio, P. Genovese, Z. Magnani, Elisa Landoni +13 more
20140 citations
Semantic Scholar

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