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Y. Kfoury · SciRah

Researcher profile · Semantic Scholar

Y. Kfoury

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Y. Kfoury — researcher profile on SciRah

h-index: 27
Works: 78
Citations: 4,033

Most-cited papers

A cellular taxonomy of the bone marrow stroma in homeostasis and leukemia
N. Baryawno, D. Przybylski, Monika S. Kowalczyk, Y. Kfoury +15 more
2019Cell772 citations Open access
Semantic Scholar
Mesenchymal cell contributions to the stem cell niche.
Y. Kfoury, D. Scadden
2015Cell Stem Cell497 citations Open access
Semantic Scholar
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
D. Sykes, Y. Kfoury, F. Mercier, M. Wawer +26 more
2016Cell432 citations Open access
Semantic Scholar
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses
Taghreed Hirz, S. Mei, Hirak Sarkar, Y. Kfoury +16 more
2023Nature Communications274 citations Open access
Semantic Scholar
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment
Y. Kfoury, N. Baryawno, N. Sévère, S. Mei +14 more
2020bioRxiv261 citations
Semantic Scholar
Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin
R. Palchaudhuri, B. Saez, Jonathan Hoggatt, A. Schajnovitz +9 more
2016Nature Biotechnology203 citations Open access
Semantic Scholar
Hematopoietic Stem Cell Niche in Health and Disease.
Jonathan Hoggatt, Y. Kfoury, D. Scadden
2016Annual Review of Pathology157 citations
Semantic Scholar
Proximity-based differential single cell analysis of the niche to identify stem/progenitor cell regulators
L. Silberstein, K. Goncalves, P. Kharchenko, R. Turcotte +22 more
2016Cell Stem Cell150 citations Open access
Semantic Scholar
Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-kappaB activation.
R. Nasr, E. Chiari, M. El-Sabban, R. Mahieux +7 more
2006Blood115 citations
Semantic Scholar
Stress-induced changes in bone marrow stromal cell populations revealed through single-cell protein expression mapping
N. Sévère, N. Karabacak, K. Gustafsson, N. Baryawno +11 more
2019Cell Stem Cell108 citations Open access
Semantic Scholar
Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia
H. El Hajj, M. El-Sabban, H. Hasegawa, G. Zaatari +11 more
2010Journal of Experimental Medicine99 citations Open access
Semantic Scholar
Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-I associated adult T-cell leukemia/lymphoma
R. Nasr, M. El-Sabban, J. Karam, G. Dbaibo +7 more
2005Oncogene87 citations Open access
Semantic Scholar
Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease
D. Rohde, K. Vandoorne, I-Hsiu Lee, J. Grune +38 more
2021Nature Cardiovascular Research85 citations Open access
Semantic Scholar
ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation.
Zeina Dassouki, Umut Şahin, H. El Hajj, F. Jollivet +5 more
2015Blood73 citations Open access
Semantic Scholar
A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma
A. Alchahin, S. Mei, Ioanna Tsea, Taghreed Hirz +11 more
2022Nature Communications67 citations Open access
Semantic Scholar
Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome
Y. Kfoury, N. Setterblad, M. El-Sabban, Alessia Zamborlini +7 more
2011Retrovirology59 citations Open access
Semantic Scholar
Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions
Sheng-Lin Mei, A. Alchahin, Ioanna Tsea, Y. Kfoury +20 more
2024Genome Medicine51 citations Open access
Semantic Scholar
Arsenic trioxide induces accumulation of cytotoxic levels of ceramide in acute promyelocytic leukemia and adult T-cell leukemia/lymphoma cells through de novo ceramide synthesis and inhibition of glucosylceramide synthase activity.
G. Dbaibo, Y. Kfoury, N. Darwiche, Shoghag Panjarian +7 more
2007Haematologica51 citations Open access
Semantic Scholar
Animal models on HTLV-1 and related viruses: what did we learn?
H. El Hajj, R. Nasr, Y. Kfoury, Zeina Dassouki +5 more
2012Front. Microbio.46 citations Open access
Semantic Scholar
The multifaceted oncoprotein Tax: subcellular localization, posttranslational modifications, and NF-κB activation.
Y. Kfoury, R. Nasr, Chloé Journo, R. Mahieux +2 more
2012Advances in Cancer Research45 citations
Semantic Scholar
Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-κB pathway
Y. Kfoury, R. Nasr, O. Hermine, H. de Thé +1 more
2005Cell Death and Differentiation44 citations
Semantic Scholar
Human T Cell Leukemia Virus Type 2 Tax-Mediated NF-κB Activation Involves a Mechanism Independent of Tax Conjugation to Ubiquitin and SUMO
Chloé Journo, Amandine Bonnet, A. Favre-Bonvin, Jocelyn Turpin +7 more
2012Journal of Virology43 citations Open access
Semantic Scholar
Controversies in Targeted Therapy of Adult T Cell Leukemia/Lymphoma: ON Target or OFF Target Effects?
R. Nasr, H. El Hajj, Y. Kfoury, H. de Thé +2 more
2011Viruses42 citations Open access
Semantic Scholar
EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I-associated adult T-cell leukemia/lymphoma.
Georges Moarbess, H. El Hajj, Y. Kfoury, M. El-Sabban +5 more
2008Blood42 citations Open access
Semantic Scholar
tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche
Y. Kfoury, Fei Ji, M. Mazzola, D. Sykes +14 more
2021bioRxiv36 citations Open access
Semantic Scholar
Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation
M. Shirinian, Y. Kfoury, Zeina Dassouki, H. El Hajj +1 more
2013Frontiers in Microbiology36 citations Open access
Semantic Scholar
KSHV-transformed primary effusion lymphoma cells induce a VEGF-dependent angiogenesis and establish functional gap junctions with endothelial cells
L. Haddad, H. El Hajj, R. Abou-Merhi, Y. Kfoury +3 more
2008Leukemia32 citations
Semantic Scholar
Amino acid–insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells
Demetrios Kalaitzidis, Dongjun Lee, A. Efeyan, Y. Kfoury +9 more
2017Journal of Clinical Investigation25 citations Open access
Semantic Scholar
SnapShot: The hematopoietic stem cell niche.
Y. Kfoury, F. Mercier, D. Scadden
2014Cell21 citations Open access
Semantic Scholar
In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies
F. Mercier, Jian-Tao Shi, D. Sykes, T. Oki +11 more
2022Blood Advances20 citations Open access
Semantic Scholar
Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors
Dongjun Lee, S. Sykes, Demetrios Kalaitzidis, A. Lane +5 more
2014Stem Cell Reports20 citations Open access
Semantic Scholar
Shipping mouse bone marrow: Keep it in the bone.
Ani Papazian, Y. Kfoury, D. Scadden
2017Experimental Hematology8 citations Open access
Semantic Scholar
The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression
Y. Kfoury, Fei Ji, E. Jain, M. Mazzola +10 more
2023Blood Advances7 citations Open access
Semantic Scholar
tiRNA signaling occurs via stress-regulated vesicle transfer in the hematopoietic niche
Y. Kfoury, Fei Ji, Michael Mazzola, David B. Sykes +15 more
2021Cell Stem Cell7 citations Open access
Semantic Scholar
Impact of metastatic prostate cancer on human bone marrow
N. Baryawno, Y. Kfoury, N. Sévère, S. Mei +11 more
20204 citations
Semantic Scholar
Cellular thrust and parry in the leukemic niche.
Y. Kfoury, D. Scadden
2014Blood4 citations Open access
Semantic Scholar
Inhibition of the Enzyme Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
D. Sykes, Y. Kfoury, F. Mercier, M. Wawer +8 more
20163 citations
Semantic Scholar
Embigin Regulates HSPC Homing and Quiescence and Acts As a Cell Surface Marker for a Niche Factor-Enriched Subset of Osteolineage Cells
L. Silberstein, P. Kharchenko, Y. Kfoury, F. Mercier +7 more
20153 citations
Semantic Scholar
Transfer of mRNA Encoding CEBPA in Lipid Nanoparticles to CEBPA Mutated Leukemia Cell Line KO52 and Primary AML Reduces Cell Growth and Induces Myeloid Differentiation
Chunxiao Zhang, Brenda Loera, Jian-Ying Zhang, Richard Gelinas +4 more
2023Blood2 citations Open access
Semantic Scholar
Myelodysplastic syndromes disable support of human hematopoietic stem and progenitor cells by CD271, VCAM- 1 and CD146 expressing marrow niche cells
Yuko Kawano, Hiroki Kawano, Dalia Ghoneim, Thomas J. Fountaine +15 more
2023bioRxiv2 citations Open access
Semantic Scholar
Integrated single-cell and spatial transcriptomic analyses unravel the heterogeneity of the prostate tumor microenvironment
Taghreed Hirz, S. Mei, Hirak Sarkar, Y. Kfoury +16 more
2022bioRxiv2 citations Open access
Semantic Scholar
A Genome-Wide, In Vivo, Dropout CRISPR Screen in Acute Myeloid Leukemia Identifies an Essential Role for Beta-Galactosylation in Leukemic Cell Homing
F. Mercier, Jian-Tao Shi, D. Sykes, Elizabeth Miller +8 more
20172 citations
Semantic Scholar
Cap-Independent Protein Translation in Hematopoiesis
M. Mazzola, Ting Zhao, K. Gustafsson, Trine Kristiansen +11 more
2022Blood1 citations Open access
Semantic Scholar
A Specific Mesenchymal Stem and Progenitor Cell (MSPC) Subpopulation with a Multi-Potent Gene Signature Is Transcriptionally Altered in the Setting of Myelodysplastic Syndrome (MDS) in Primary Human Bone Marrow Aspirates
Thomas J. Fountaine, M. LaMere, D. Byun, Jason R. Myers +6 more
2019Blood1 citations Open access
Semantic Scholar
DHODH Inhibitors in the Treatment of Acute Myeloid Leukemia: Defining the Mechanism of Action and the Basis of the Metabolic Therapeutic Window
Peggy P. Hsu, Y. Kfoury, N. Aziz, Jenna Elkhoury +4 more
2018Blood1 citations Open access
Semantic Scholar
Distinct Stress Responses of Bone Marrow Stromal Cell Subgroups Defined by Unbiased Single-Cell Mass-Cytometry Analysis
N. Sévère, M. Karabacak, N. Baryawno, K. Gustafsson +3 more
20161 citations
Semantic Scholar
Tax as a therapeutic target in ATL
Zeina Dassouki, Umut Şahin, H. El Hajj, F. Jollivet +5 more
2015Retrovirology1 citations Open access
Semantic Scholar
Tax as a therapeutic target in ATL
Zeina Dassouki, Umut Şahin, H. El Hajj, F. Jollivet +5 more
2015Retrovirology1 citations Open access
Semantic Scholar
Proximity-Based Single Cell Analysis of the Bone Marrow Niche Identifies Interleukin-18 As a Quiescence Regulator of Early Hematopoietic Progenitors
L. Silberstein, P. Kharchenko, Y. Kfoury, F. Mercier +5 more
20141 citations
Semantic Scholar
Low levels of HTLV-2 Tax conjugation to ubiquitin and SUMO do not impede Tax-mediated activation of NF-κB
Chloé Journo, Amandine Bonnet, A. Favre-Bonvin, Jocelyn Turpin +7 more
2014Retrovirology1 citations Open access
Semantic Scholar

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