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Amy J. Ziemba · SciRah

Researcher profile · Semantic Scholar

Amy J. Ziemba

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Amy J. Ziemba — researcher profile on SciRah

h-index: 14
Works: 28
Citations: 611

Most-cited papers

Disruption of uridine homeostasis links liver pyrimidine metabolism to lipid accumulation[S]
T. T. Le, Amy J. Ziemba, Y. Urasaki, Eugene Hayes +2 more
2013Journal of Lipid Research106 citations Open access
Semantic Scholar
E2 enzyme inhibition by stabilization of a low affinity interface with ubiquitin
Hao Huang, D. Ceccarelli, S. Orlicky, D. St-Cyr +9 more
2013Nature Chemical Biology87 citations Open access
Semantic Scholar
Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein.
J. Huggenvik, Rhett J. Michelson, M. Collard, Amy J. Ziemba +2 more
1998Molecular Endocrinology84 citations Open access
Semantic Scholar
Nuclear DEAF-1-related (NUDR) Protein Contains a Novel DNA Binding Domain and Represses Transcription of the Heterogeneous Nuclear Ribonucleoprotein A2/B1 Promoter*
Rhett J. Michelson, M. Collard, Amy J. Ziemba, Jim Persinger +2 more
1999Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Label-free Evaluation of Hepatic Microvesicular Steatosis with Multimodal Coherent Anti-Stokes Raman Scattering Microscopy
T. T. Le, Amy J. Ziemba, Y. Urasaki, S. Brotman +1 more
2012PLoS ONE41 citations Open access
Semantic Scholar
Peptide nucleic acid conjugates: synthesis, properties and applications.
Zhanna V. Zhilina, Amy J. Ziemba, S. Ebbinghaus
2005Current Topics in Medicinal Chemistry30 citations
Semantic Scholar
A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity
T. Roosild, S. Castronovo, A. Villoso, Amy J. Ziemba +1 more
2011Journal of Structural Biology28 citations Open access
Semantic Scholar
Ubiquitin-conjugating Enzyme Cdc34 and Ubiquitin Ligase Skp1-Cullin-F-box Ligase (SCF) Interact through Multiple Conformations*
Daniella Sandoval, Spencer Hill, Amy J. Ziemba, S. Lewis +2 more
2014Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Tumor growth factor expression in obesity and changes in expression with weight loss: another cause of increased virulence and incidence of cancer in obesity.
D. Cottam, B. Fisher, Amy J. Ziemba, James Atkinson +3 more
2010Surgery for Obesity and Related Diseases24 citations
Semantic Scholar
Development of an Oral Form of Azacytidine: 2′3′5′Triacetyl-5-Azacytidine
Amy J. Ziemba, Eugene Hayes, B. Freeman, T. Ye +1 more
2011Chemotherapy Research and Practice21 citations Open access
Semantic Scholar
Multimodal Mechanism of Action for the Cdc34 Acidic Loop
Amy J. Ziemba, Spencer Hill, Daniella Sandoval, Kristofor J. Webb +2 more
2013Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Differential expression of uridine phosphorylase in tumors contributes to an improved fluoropyrimidine therapeutic activity
D. Cao, Amy J. Ziemba, J. Mccabe, R. Yan +5 more
2011Molecular Cancer Therapeutics17 citations Open access
Semantic Scholar
PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions.
Zhanna V. Zhilina, Amy J. Ziemba, P. Nielsen, S. Ebbinghaus
2006Bioconjugate chemistry17 citations
Semantic Scholar
Repair of triplex-directed DNA alkylation by nucleotide excision repair.
Amy J. Ziemba, L. C. Derosier, Russell Methvin, Chun-Yang Song +6 more
2001Nucleic Acids Research15 citations Open access
Semantic Scholar
Activation of Stat1, IRF-1, and NF-κB is Required for the Induction of Uridine Phosphorylase by Tumor Necrosis Factor-α and Interferon-γ
Laxiang Wan, D. Cao, Jianmin Zeng, Amy J. Ziemba +1 more
2010Nucleosides, Nucleotides & Nucleic Acids11 citations
Semantic Scholar
Targeting and Regulation of the HER-2/neu Oncogene Promoter with Bis-Peptide Nucleic Acids
Amy J. Ziemba, Zhanna V. Zhilina, Yulia Krotova-Khan, L. Staňková +1 more
2005Oligonucleotides10 citations
Semantic Scholar
A bis-alkylating triplex forming oligonucleotide inhibits intracellular reporter gene expression and prevents triplex unwinding due to helicase activity.
Amy J. Ziemba, M. W. Reed, K. Raney, Al Byrd +1 more
2003Biochemistry9 citations
Semantic Scholar
Synthesis and evaluation of a triplex-forming oligonucleotide-pyrrolobenzodiazepine conjugate.
Zhanna V. Zhilina, Amy J. Ziemba, J. Trent, M. W. Reed +5 more
2004Bioconjugate chemistry8 citations
Semantic Scholar
Abstract 52: Overexpression of uridine phosphorylase 2 (UPP2) in tissues of uridine phosphorylase (UPP1) knock-out mice
Yang Gao, Amy J. Ziemba, J. Turner, G. Pizzorno
20102 citations
Semantic Scholar
Tissue expression of Uridine and Thymidine phosphorylases and NF-κB in breast cancer patients by tissue microarray
Mary M. McCarthy, Laxiang Wan, Amy J. Ziemba, H. Kluger +1 more
20071 citations
Semantic Scholar
Abstract 4390: Role of uridine phosphorylase 2 in fluoropyrimidine activation and host toxicity
Amy J. Ziemba, S. Brotman, Yang Gao, M. Hirano +1 more
20110 citations
Semantic Scholar
448 Regulation of uridine phosphorylase-2 redox-control mechanism to improve capecitabine selectivity
G. Pizzorno, Amy J. Ziemba, T. T. Le, S. Brotman +4 more
20100 citations
Semantic Scholar
PL-305: The effect of weight loss surgery on the expression of tumor growth factors in morbid obesity
D. Cottam, B. Fisher, G. Pizzorno, Amy J. Ziemba
20090 citations
Semantic Scholar
Mechanism of PNA Transport to the Nuclear Compartment
L. Staňková, Amy J. Ziemba, Zhanna V. Zhilina, S. Ebbinghaus
2006Annals of the New York Academy of Sciences0 citations
Semantic Scholar
Antigen Effects of Peptide Nucleic Acids on HIF-1α Expression
Zhanna V. Zhilina, Amy J. Ziemba, L. Staňková, Stacey Wood +2 more
20060 citations
Semantic Scholar
Peptide Nucleic Acid Conjugates: Synthesis, Properties and Applications
Zhanna V. Zhilina, Amy J. Ziemba, S. Ebbinghaus
20060 citations
Semantic Scholar
Synthesis of PNA-Alkylator conjugates to target the HER-2/neu promoter
Zhanna V. Zhilina, Amy J. Ziemba, L. Staňková, Meghan C. Boros +2 more
20050 citations
Semantic Scholar
Targeting and regulation of HER-2/neu gene expression using a bis-peptide nucleic acid.
Amy J. Ziemba, Zhanna V. Zhilina, S. Ebbinghaus
20040 citations
Semantic Scholar

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