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Kirby D. Johnson · SciRah

Researcher profile · Semantic Scholar

Kirby D. Johnson

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Kirby D. Johnson — researcher profile on SciRah

h-index: 35
Works: 83
Citations: 4,130

Most-cited papers

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
Jaeseob Kim, Kirby D. Johnson, Hui-Ju Chen, S. Carroll +1 more
1997Nature546 citations
Semantic Scholar
GATA Switches as Developmental Drivers*
E. Bresnick, Hsiang-Ying Lee, Tohru Fujiwara, Kirby D. Johnson +1 more
2010Journal of Biological Chemistry276 citations Open access
Semantic Scholar
GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome.
Amy P. Hsu, Kirby D. Johnson, E. Falcone, Rajendran Sanalkumar +7 more
2013Blood249 citations Open access
Semantic Scholar
Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.
Kirby D. Johnson, Amy P. Hsu, Myung‐Jeom Ryu, Jin-Yong Wang +9 more
2012Journal of Clinical Investigation203 citations Open access
Semantic Scholar
Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter.
Kirby D. Johnson, Heather M. Christensen, Bryan M. Zhao, E. Bresnick
2001Molecules and Cells192 citations Open access
Semantic Scholar
Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies
E. Bresnick, Koichi R. Katsumura, Hsiang-Ying Lee, Kirby D. Johnson +1 more
2012Nucleic Acids Research187 citations Open access
Semantic Scholar
Coregulator-dependent facilitation of chromatin occupancy by GATA-1.
Saumen Pal, A. Cantor, Kirby D. Johnson, Tyler B. Moran +3 more
2004Proceedings of the National Academy of Sciences of the United States of America156 citations Open access
Semantic Scholar
Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo
Xin Gao, Kirby D. Johnson, Yuan-I Chang, Meghan E. Boyer +3 more
2013Journal of Experimental Medicine153 citations Open access
Semantic Scholar
Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region.
Hogune Im, Jeffrey A. Grass, Kirby D. Johnson, Shin-Il Kim +4 more
2005Proceedings of the National Academy of Sciences of the United States of America144 citations Open access
Semantic Scholar
Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain
Kirby D. Johnson, Jeffrey A. Grass, Meghan E. Boyer, C. Kiekhaefer +3 more
2002Proceedings of the National Academy of Sciences of the United States of America135 citations Open access
Semantic Scholar
Dissecting long-range transcriptional mechanisms by chromatin immunoprecipitation.
Kirby D. Johnson, E. Bresnick
2002Methods127 citations
Semantic Scholar
Developmental control via GATA factor interplay at chromatin domains
E. Bresnick, Melissa L. Martowicz, Saumen Pal, Kirby D. Johnson
2005Journal of Cellular Physiology112 citations Open access
Semantic Scholar
Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation.
Hogune Im, Jeffrey A. Grass, Kirby D. Johnson, Meghan E. Boyer +2 more
2004Methods in molecular biology106 citations
Semantic Scholar
Hematopoietic-specific activators establish an overlapping pattern of histone acetylation and methylation within a mammalian chromatin domain
C. Kiekhaefer, Jeffrey A. Grass, Kirby D. Johnson, Meghan E. Boyer +1 more
2002Proceedings of the National Academy of Sciences of the United States of America101 citations Open access
Semantic Scholar
Interaction of Smad Complexes with Tripartite DNA-binding Sites*
Kirby D. Johnson, H. Kirkpatrick, A. Comer, F. Hoffmann +1 more
1999Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Repression of Dpp Targets by Binding of Brinker to Mad Sites*
H. Kirkpatrick, Kirby D. Johnson, A. Laughon
2001Journal of Biological Chemistry87 citations Open access
Semantic Scholar
Highly Restricted Localization of RNA Polymerase II within a Locus Control Region of a Tissue-Specific Chromatin Domain
Kirby D. Johnson, Jeffrey A. Grass, Changwon Park, Hogune Im +2 more
2003Molecular and Cellular Biology85 citations Open access
Semantic Scholar
Mechanisms of erythrocyte development and regeneration: implications for regenerative medicine and beyond
E. Bresnick, K. Hewitt, Charu Mehta, S. Keleş +2 more
2018Development74 citations Open access
Semantic Scholar
Dynamic Regulation of Histone H3 Methylated at Lysine 79 within a Tissue-specific Chromatin Domain*
Hogune Im, Changwon Park, Qin Feng, Kirby D. Johnson +4 more
2003Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Cis-regulatory mechanisms governing stem and progenitor cell transitions
Kirby D. Johnson, Guangyao Kong, Xin Gao, Yuan-I Chang +7 more
2015Science Advances67 citations Open access
Semantic Scholar
Friend of GATA-1-independent transcriptional repression: a novel mode of GATA-1 function.
Kirby D. Johnson, Meghan E. Boyer, Jeong-Ah Kang, A. Wickrema +2 more
2007Blood65 citations Open access
Semantic Scholar
Context-dependent function of "GATA switch" sites in vivo.
Jonathan W. Snow, Jennifer J. Trowbridge, Kirby D. Johnson, Tohru Fujiwara +4 more
2011Blood56 citations Open access
Semantic Scholar
Controlling Hematopoiesis Through Sumoylation-Dependent Regulation of a GATA Factor
Hsiang-Ying Lee, Kirby D. Johnson, Tohru Fujiwara, Meghan E. Boyer +2 more
2009Molecules and Cells54 citations Open access
Semantic Scholar
Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program
Charu Mehta, Kirby D. Johnson, Xin Gao, I. Ong +4 more
2017Cell Reports53 citations Open access
Semantic Scholar
Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer
Alexandra A. Soukup, Ye Zheng, Charu Mehta, Jun Wu +9 more
2019Journal of Clinical Investigation49 citations Open access
Semantic Scholar
Requirement of an E1A-sensitive Coactivator for Long-range Transactivation by the β-Globin Locus Control Region*
E. Forsberg, Kirby D. Johnson, Tatiana N. Zaboikina, Eric A. Mosser +1 more
1999Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Mechanism governing a stem cell-generating cis-regulatory element
Rajendran Sanalkumar, Kirby D. Johnson, Xin Gao, Meghan E. Boyer +4 more
2014Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Human leukemia mutations corrupt but do not abrogate GATA-2 function
Koichi R. Katsumura, Charu Mehta, K. Hewitt, Alexandra A. Soukup +4 more
2018Proceedings of the National Academy of Sciences of the United States of America45 citations Open access
Semantic Scholar
Differential sensitivities of transcription factor target genes underlie cell type-specific gene expression profiles
Kirby D. Johnson, Shin-Il Kim, Megan E. Boyer, E. Bresnick
2006Proceedings of the National Academy of Sciences of the United States of America44 citations Open access
Semantic Scholar
Hematopoietic Signaling Mechanism Revealed From a Stem/Progenitor Cell Cistrome
K. Hewitt, Duk-Hyoung Kim, Prithvia Devadas, R. Prathibha +8 more
2015Molecules and Cells42 citations Open access
Semantic Scholar
Transcriptional mechanisms underlying hemoglobin synthesis.
Koichi R. Katsumura, A. DeVilbiss, Nathaniel J. Pope, Kirby D. Johnson +1 more
2013Cold Spring Harbor Perspectives in Medicine42 citations Open access
Semantic Scholar
A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis.
Kaisheng Huang, Kirby D. Johnson, Andrei G. Petcherski, T. Vandergon +5 more
2000Gene41 citations
Semantic Scholar
Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories
Kirby D. Johnson, Daniel J Conn, Evgenia Shishkova, Koichi R. Katsumura +11 more
2020Journal of Experimental Medicine39 citations Open access
Semantic Scholar
Relocalizing Genetic Loci into Specific Subnuclear Neighborhoods*
Hsiang-Ying Lee, Kirby D. Johnson, Meghan E. Boyer, E. Bresnick
2011Journal of Biological Chemistry37 citations Open access
Semantic Scholar
p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia.
Jing-Fang Zhang, Guangyao Kong, Adhithi Rajagopalan, Li Lu +17 more
2017Blood35 citations Open access
Semantic Scholar
The Hematopoietic Stem and Progenitor Cell Cistrome: GATA Factor-Dependent cis-Regulatory Mechanisms
K. Hewitt, Kirby D. Johnson, Xin Gao, S. Keleş +1 more
2016Current Topics in Developmental Biology28 citations Open access
Semantic Scholar
Establishment and regulation of chromatin domains: mechanistic insights from studies of hemoglobin synthesis.
E. Bresnick, Kirby D. Johnson, Shin-Il Kim, Hogune Im
2006Progress in Nucleic Acid Research and Molecular Biology28 citations
Semantic Scholar
Blood disease-causing and -suppressing transcriptional enhancers: general principles and GATA2 mechanisms.
E. Bresnick, Kirby D. Johnson
2019Blood Advances26 citations Open access
Semantic Scholar
Hematopoietic Transcriptional Mechanisms: From Locus-Specific to Genome-Wide Vantage Points
A. DeVilbiss, Rajendran Sanalkumar, Kirby D. Johnson, S. Keleş +1 more
2014Experimental Hematology23 citations Open access
Semantic Scholar
A WW Domain-binding Motif within the Activation Domain of the Hematopoietic Transcription Factor NF-E2 Is Essential for Establishment of a Tissue-specific Histone Modification Pattern*
C. Kiekhaefer, Meghan E. Boyer, Kirby D. Johnson, E. Bresnick
2004Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Navigating Transcriptional Coregulator Ensembles to Establish Genetic Networks: A GATA Factor Perspective.
A. DeVilbiss, Nobuyuki Tanimura, S. C. McIver, Koichi R. Katsumura +2 more
2016Current Topics in Developmental Biology18 citations
Semantic Scholar
Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks
M. Jung, Siqi Shen, G. Botten, Thomas Olender +16 more
2023Journal of Clinical Investigation14 citations Open access
Semantic Scholar
GATA2 deficiency elevates interferon regulatory factor-8 to subvert a progenitor cell differentiation program
Kirby D. Johnson, Alexandra A. Soukup, E. Bresnick
2022Blood Advances14 citations Open access
Semantic Scholar
Conditionally pathogenic genetic variants of a hematopoietic disease–suppressing enhancer
Alexandra A. Soukup, D. Matson, P. Liu, Kirby D. Johnson +1 more
2021Science Advances14 citations Open access
Semantic Scholar
GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis
Xin Gao, Tong-Yu Wu, Kirby D. Johnson, Jamie L. Lahvic +3 more
2016Stem Cell Reports14 citations Open access
Semantic Scholar
Restricting genomic actions of innate immune mediators on fetal hematopoietic progenitor cells
Vu L. Tran, P. Liu, Koichi R. Katsumura, Erin Kim +3 more
2023iScience12 citations Open access
Semantic Scholar
Gata2 +9.5 enhancer regulates adult hematopoietic stem cell self-renewal and T-cell development
Xiaona You, Yun Zhou, Yuan-I Chang, Guangyao Kong +5 more
2021Blood Advances12 citations Open access
Semantic Scholar
Epigenetic and genetic mechanisms in red cell biology
K. Hewitt, Rajendran Sanalkumar, Kirby D. Johnson, S. Keleş +1 more
2014Current opinion in hematology12 citations Open access
Semantic Scholar
Requirements for utilization of CREB binding protein by hypersensitive site two of the beta-globin locus control region.
Kirby D. Johnson, J. Norton, E. Bresnick
2002Nucleic Acids Research8 citations Open access
Semantic Scholar
Interferon Regulatory Factor-8-Dependent Innate Immune Alarm Senses GATA2 Deficiency to Alter Hematopoietic Differentiation and Function
Kirby D. Johnson, M. Jung, Vu L. Tran, E. Bresnick
2023Current opinion in hematology7 citations
Semantic Scholar

Frequent co-authors

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E. Bresnick×47
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E. Bresnick — researcher profile on SciRah
Meghan E. Boyer×12
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Meghan E. Boyer — researcher profile on SciRah
S. Keleş×10
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Koichi R. Katsumura×8
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Koichi R. Katsumura — researcher profile on SciRah

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Jing Zhang — researcher profile on SciRah

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K. Hewitt — researcher profile on SciRah

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Rajendran Sanalkumar×6

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Rajendran Sanalkumar — researcher profile on SciRah

Jeffrey A. Grass×6

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Jeffrey A. Grass — researcher profile on SciRah

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Xin Gao — researcher profile on SciRah

Alexandra A. Soukup×6

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Alexandra A. Soukup — researcher profile on SciRah

Yuan-I Chang×5

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Yuan-I Chang — researcher profile on SciRah