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Guangyao Kong · SciRah

Researcher profile · Semantic Scholar

Guangyao Kong

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Guangyao Kong — researcher profile on SciRah

h-index: 24
Works: 54
Citations: 2,023

Most-cited papers

Elevation of Highly Up-regulated in Liver Cancer (HULC) by Hepatitis B Virus X Protein Promotes Hepatoma Cell Proliferation via Down-regulating p18*
Yumei Du, Guangyao Kong, Xiaona You, Shuai Zhang +4 more
2012Journal of Biological Chemistry356 citations Open access
Semantic Scholar
Upregulated MicroRNA-29a by Hepatitis B Virus X Protein Enhances Hepatoma Cell Migration by Targeting PTEN in Cell Culture Model
Guangyao Kong, Junping Zhang, Shuai Zhang, Changliang Shan +2 more
2011PLoS ONE178 citations Open access
Semantic Scholar
Hepatitis B virus X protein modulates oncogene yes‐associated protein by CREB to promote growth of hepatoma cells
Tao Zhang, Junping Zhang, Xiaona You, Qian Liu +8 more
2012Hepatology175 citations Open access
Semantic Scholar
miR-520b Regulates Migration of Breast Cancer Cells by Targeting Hepatitis B X-interacting Protein and Interleukin-8*
Nan Hu, Jian-Li Zhang, Wenjing Cui, Guangyao Kong +7 more
2011Journal of Biological Chemistry113 citations Open access
Semantic Scholar
MicroRNA-520b Inhibits Growth of Hepatoma Cells by Targeting MEKK2 and Cyclin D1
Wei-Ying Zhang, Guangyao Kong, Junping Zhang, Tao Wang +2 more
2012PLoS ONE88 citations Open access
Semantic Scholar
PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism
Ming-Ming Sun, Leilei Li, Yujia Niu, Yingzhi Wang +24 more
2022Acta Pharmaceutica Sinica B74 citations Open access
Semantic Scholar
Cis-regulatory mechanisms governing stem and progenitor cell transitions
Kirby D. Johnson, Guangyao Kong, Xin Gao, Yuan-I Chang +7 more
2015Science Advances67 citations Open access
Semantic Scholar
Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions.
Jin-Yong Wang, Guangyao Kong, Yangang Liu, Juan Du +9 more
2013Blood67 citations Open access
Semantic Scholar
Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signaling pathway
Hong-Da Li, Xiao-Fen Zhong, Kevin F. Chau, Nicholas J. Santistevan +10 more
2014Nature Communications65 citations Open access
Semantic Scholar
Hepatitis B virus X protein accelerates hepatocarcinogenesis with partner survivin through modulating miR-520b and HBXIP
Wei-Ying Zhang, Zhanping Lu, Guangyao Kong, Yuen Gao +7 more
2014Molecular Cancer59 citations Open access
Semantic Scholar
Loss of Dnmt3a and endogenous KrasG12D/+ cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis
Yuan-I Chang, Xiaona You, Guangyao Kong, E. Ranheim +6 more
2015Leukemia53 citations Open access
Semantic Scholar
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
Guangyao Kong, M. Wunderlich, David T Yang, E. Ranheim +13 more
2014Journal of Clinical Investigation52 citations Open access
Semantic Scholar
Increased transport of acetyl‐CoA into the endoplasmic reticulum causes a progeria‐like phenotype
Yajing Peng, Samantha L. Shapiro, V. C. Banduseela, Inca A. Dieterich +14 more
2018Aging Cell51 citations Open access
Semantic Scholar
Polycomb Group Protein YY1 Is an Essential Regulator of Hematopoietic Stem Cell Quiescence
Zhanping Lu, C. Hong, Guangyao Kong, Anna L. F. V. Assumpcao +4 more
2018Cell Reports50 citations Open access
Semantic Scholar
HBXIP upregulates CD46, CD55 and CD59 through ERK1/2/NF‐κB signaling to protect breast cancer cells from complement attack
Wenjing Cui, Yu Zhao, Changliang Shan, Guangyao Kong +7 more
2012FEBS Letters49 citations
Semantic Scholar
Asxl1loss cooperates with oncogenic Nras in mice to reprogram immune microenvironment and drive leukemic transformation.
Xiaona You, Fabao Liu, M. Binder, A. Vedder +26 more
2021Blood48 citations Open access
Semantic Scholar
Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis
Guangyao Kong, Yuan-I Chang, A. Damnernsawad, Xiaona You +9 more
2016Leukemia47 citations Open access
Semantic Scholar
Gasotransmitters: Potential Therapeutic Molecules of Fibrotic Diseases
Ying-Qing Chen, Shuo Yuan, Yuying Cao, Guangyao Kong +7 more
2021Oxidative Medicine and Cellular Longevity42 citations Open access
Semantic Scholar
Kras is required for adult hematopoiesis
A. Damnernsawad, Guangyao Kong, Zhi Wen, Yangang Liu +8 more
2016Stem Cells40 citations Open access
Semantic Scholar
Hepatitis B virus X protein activates CD59 involving DNA binding and let-7i in protection of hepatoma and hepatic cells from complement attack.
Changliang Shan, Shuai Zhang, Wenjing Cui, Xiaona You +5 more
2011Carcinogenesis38 citations Open access
Semantic Scholar
Unique dependence on Sos1 in Kras G12D -induced leukemogenesis.
Xiaona You, Guangyao Kong, E. Ranheim, David T Yang +2 more
2018Blood37 citations Open access
Semantic Scholar
p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia.
Jing-Fang Zhang, Guangyao Kong, Adhithi Rajagopalan, Li Lu +17 more
2017Blood35 citations Open access
Semantic Scholar
Notch1 Gene Mutations Target KRAS G12D-expressing CD8+ Cells and Contribute to Their Leukemogenic Transformation*
Guangyao Kong, Juan Du, Yangang Liu, B. Meline +4 more
2013Journal of Biological Chemistry34 citations Open access
Semantic Scholar
The ability of endogenous Nras oncogenes to initiate leukemia is codon-dependent
Guangyao Kong, Yuan-I Chang, Xiaona You, E. Ranheim +3 more
2016Leukemia24 citations Open access
Semantic Scholar
Oncogenic Kras Expression in Postmitotic Neurons Leads to S100A8-S100A9 Protein Overexpression and Gliosis*
Myung‐Jeom Ryu, Yangang Liu, Xiao-Fen Zhong, Juan Du +7 more
2012Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Hepatitis B virus X protein protects hepatoma and hepatic cells from complement‐dependent cytotoxicity by up‐regulation of CD46
Shuai Zhang, Changliang Shan, Wenjing Cui, Xiaona You +5 more
2013FEBS Letters22 citations
Semantic Scholar
Hepatitis B virus X protein promotes hepatoma cell proliferation via upregulation of MEKK2
Guangyao Kong, Junping Zhang, Shuai Zhang, Changliang Shan +2 more
2011Acta Pharmacologica Sinica20 citations Open access
Semantic Scholar
Loss of CD44 attenuates aberrant GM-CSF signaling in Kras G12D hematopoietic progenitor/precursor cells and prolongs the survival of diseased animals
Juan Du, Yangang Liu, B. Meline, Guangyao Kong +9 more
2012Leukemia17 citations Open access
Semantic Scholar
Signaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells
Juan Du, Jin-Yong Wang, Guangyao Kong, Jing Jiang +4 more
2012Stem Cells16 citations Open access
Semantic Scholar
Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation
Yuan-I Chang, A. Damnernsawad, Laura K. Allen, David T Yang +11 more
2014British Journal of Haematology14 citations Open access
Semantic Scholar
NrasQ61R/+ and Kras−/− cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors
Zhi Wen, Grant Yun, Alexander S. Hebert, Guangyao Kong +12 more
2021Blood13 citations Open access
Semantic Scholar
Gasotransmitter CO Attenuates Bleomycin-Induced Fibroblast Senescence via Induction of Stress Granule Formation
Ying-Qing Chen, Feng Jiang, Guangyao Kong, Shuo Yuan +4 more
2021Oxidative Medicine and Cellular Longevity12 citations Open access
Semantic Scholar
Gata2 +9.5 enhancer regulates adult hematopoietic stem cell self-renewal and T-cell development
Xiaona You, Yun Zhou, Yuan-I Chang, Guangyao Kong +5 more
2021Blood Advances12 citations Open access
Semantic Scholar
Dnmt3a haploinsufficiency cooperates with oncogenic Kras to promote an early-onset T-cell acute lymphoblastic leukemia.
Yuan-I Chang, Guangyao Kong, E. Ranheim, Po-Shu Tu +2 more
2017American journal of translational research8 citations
Semantic Scholar
Deficiency of β Common Receptor Moderately Attenuates the Progression of Myeloproliferative Neoplasm in NrasG12D/+ Mice*
Jing-Fang Zhang, E. Ranheim, Juan Du, Yangang Liu +3 more
2015Journal of Biological Chemistry6 citations Open access
Semantic Scholar
Gata2 −77 enhancer regulates adult hematopoietic stem cell survival
Xiaona You, Yuan-I Chang, Guangyao Kong, E. Ranheim +5 more
2020Leukemia5 citations Open access
Semantic Scholar
The mystery of oncogenic KRAS: Lessons from studying its wild-type counter part
Yuan-I Chang, A. Damnernsawad, Guangyao Kong, Xiaona You +2 more
2017Small GTPases5 citations Open access
Semantic Scholar
Kras Plays An Important Role In Generating Differentiated Blood Cells
Guangyao Kong, Yangang Liu, Yuan-I Chang, Jing-Fang Zhang +2 more
20133 citations
Semantic Scholar
SYSTEMIC OVEREXPRESSION OF AT-1/SLC33A1 CAUSES A PROGERIA-LIKE PHENOTYPE
Yajing Peng, Samantha L. Shapiro, K. Hewitt, Guangyao Kong +3 more
20172 citations Open access
Semantic Scholar
MYELOID NEOPLASIA NrasG 12 D / 1 promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions
Jin-Yong Wang, Guangyao Kong, Yangang Liu, Juan Du +9 more
20132 citations
Semantic Scholar
Loss of Asxl1 Cooperates with Oncogenic Nras to Drive CMML Progression
Xiaona You, Zhi Wen, Guangyao Kong, Adhithi Rajagopalan +4 more
2019Blood1 citations Open access
Semantic Scholar
Loss of Sos1 Inhibits Oncogenic Kras-Induced Hyperactivation of Wild-Type Ras during Leukemogenesis
Xiaona You, Guangyao Kong, E. Ranheim, Yun Zhou +1 more
20161 citations
Semantic Scholar
Hepatitis B virus X protein accelerates hepatocarcinogenesis with partner survivin through modulating miR-520b and HBXIP
Wei-Ying Zhang, Zhanping Lu, Guangyao Kong, Yuen Gao +7 more
2014Molecular Cancer1 citations Open access
Semantic Scholar
Systemic Notch downregulation promotes KrasG12D‐induced myeloproliferative neoplasm
Xiaona You, Zhi Wen, Yuan-I Chang, E. Ranheim +4 more
2019British Journal of Haematology0 citations
Semantic Scholar
Dnmt3a Haploisufficiency Cooperates with Oncogenic Kras to Promote an Early-Onset T-Cell Leukemia
Yuan-I Chang, Guangyao Kong, Jing Zhang, E. Ranheim
20160 citations
Semantic Scholar
Polycomb group protein Yin Yang 1 controls quiescence and self-renewal potential in hematopoietic stem cells
Xuan Pan, C. Hong, Guangyao Kong
20160 citations Open access
Semantic Scholar
Downregulating Notch Counteracts KrasG12D-Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm
Guangyao Kong, Yuan-I Chang, Jing-Fang Zhang, E. Ranheim +6 more
20160 citations Open access
Semantic Scholar
Abstract B22: Combined MEK and JAK inhibition rescues mutant hematopoietic stem cell function and provides long-term survival in NrasG12D/G12D mice
Guangyao Kong, W. Mark, David T Yang, E. Ranheim +13 more
20140 citations
Semantic Scholar
Abstract A56: Loss of wild-type Kras promotes oncogenic Kras-induced leukemogenesis
Yuan-I Chang, A. Damnernsawad, Guangyao Kong, Yangang Liu +2 more
20140 citations
Semantic Scholar
Downregulating Notch Signaling in KrasG12D/+ Mice Inhibits Both T-Cell Leukemia and Myeloproliferative Neoplasm in a Cell-Autonomous Manner
Guangyao Kong, Yuan-I Chang, E. Ranheim, Yun Zhou +6 more
20140 citations
Semantic Scholar

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