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S. Omiya · SciRah

Researcher profile · Semantic Scholar

S. Omiya

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S. Omiya — researcher profile on SciRah

h-index: 18
Works: 42
Citations: 2,873

Most-cited papers

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
Atsuko Nakai, Osamu Yamaguchi, Toshihiro Takeda, Y. Higuchi +10 more
2007Nature Medicine1,526 citations
Semantic Scholar
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
Tomokazu Murakawa, Osamu Yamaguchi, Ayako Hashimoto, S. Hikoso +16 more
2015Nature Communications451 citations Open access
Semantic Scholar
A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy
Tomokazu Murakawa, K. Okamoto, S. Omiya, Manabu Taneike +2 more
2019Cell Reports118 citations Open access
Semantic Scholar
Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice
Jumpei Ito, S. Omiya, Mara Rusu, Hiromichi Ueda +9 more
2021eLife116 citations Open access
Semantic Scholar
Apoptosis Signal-Regulating Kinase 1/p38 Signaling Pathway Negatively Regulates Physiological Hypertrophy
M. Taniike, Osamu Yamaguchi, I. Tsujimoto, S. Hikoso +11 more
2008Circulation67 citations Open access
Semantic Scholar
Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes.
S. Omiya, S. Hikoso, Y. Imanishi, Atsuhiro Saito +11 more
2008Journal of Molecular and Cellular Cardiology66 citations
Semantic Scholar
The I&kgr;B Kinase β/Nuclear Factor &kgr;B Signaling Pathway Protects the Heart From Hemodynamic Stress Mediated by the Regulation of Manganese Superoxide Dismutase Expression
S. Hikoso, Osamu Yamaguchi, Yuko Nakano, Toshihiro Takeda +13 more
2009Circulation Research63 citations Open access
Semantic Scholar
mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy
Manabu Taneike, K. Nishida, S. Omiya, Elham Zarrinpashneh +8 more
2016PLoS ONE51 citations Open access
Semantic Scholar
Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading.
Jota Oyabu, Osamu Yamaguchi, S. Hikoso, Toshihiro Takeda +10 more
2013Biochemical and Biophysical Research Communications - BBRC51 citations
Semantic Scholar
Effect of elevated left ventricular diastolic filling pressure on the frequency of left atrial appendage thrombus in patients with nonvalvular atrial fibrillation.
K. Iwakura, A. Okamura, Y. Koyama, M. Date +12 more
2011American Journal of Cardiology51 citations
Semantic Scholar
Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation.
S. Omiya, Y. Omori, Manabu Taneike, A. Protti +5 more
2016American Journal of Physiology. Heart and Circulatory Physiology48 citations Open access
Semantic Scholar
FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice
T. Misaka, Tomokazu Murakawa, K. Nishida, Y. Omori +8 more
2018Journal of Molecular and Cellular Cardiology42 citations Open access
Semantic Scholar
NF-κB activation in cardiac fibroblasts results in the recruitment of inflammatory Ly6Chi monocytes in pressure-overloaded hearts
Hajime Abe, Y. Tanada, S. Omiya, Mihai-Nicolae Podaru +6 more
2021Science Signaling41 citations Open access
Semantic Scholar
Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure.
Tetsuya Watanabe, Toshihiro Takeda, S. Omiya, S. Hikoso +15 more
2008Journal of the American College of Cardiology37 citations Open access
Semantic Scholar
Ablation of Toll-like receptor 9 attenuates myocardial ischemia/reperfusion injury in mice
Rika Kitazume-Taneike, Manabu Taneike, S. Omiya, T. Misaka +6 more
2019Biochemical and Biophysical Research Communications - BBRC34 citations Open access
Semantic Scholar
Administration of a TLR9 Inhibitor Attenuates the Development and Progression of Heart Failure in Mice
Hiromichi Ueda, Osamu Yamaguchi, Manabu Taneike, Y. Akazawa +8 more
2019JACC: Basic to Translational Science32 citations Open access
Semantic Scholar
Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts
S. Omiya, Y. Omori, Manabu Taneike, Tomokazu Murakawa +8 more
2020Circulation31 citations Open access
Semantic Scholar
AMPK regulates Bcl2-L-13-mediated mitophagy induction for cardioprotection
Tomokazu Murakawa, J. Ito, Mara Rusu, Manabu Taneike +13 more
2024Cell Reports21 citations Open access
Semantic Scholar
Automated assessment of myocardial viability after acute myocardial infarction by global longitudinal peak strain on low-dose dobutamine stress echocardiography.
K. Iwakura, A. Okamura, Y. Koyama, M. Date +14 more
2010Circulation Journal11 citations Open access
Semantic Scholar
Rubicon-regulated beta-1 adrenergic receptor recycling protects the heart from pressure overload
Y. Akazawa, Manabu Taneike, Hiromichi Ueda, Rika Kitazume-Taneike +12 more
2022Scientific Reports8 citations Open access
Semantic Scholar
Lysophosphatidylserine induces necrosis in pressure overloaded male mouse hearts via G protein coupled receptor 34
Ryuta Sugihara, Manabu Taneike, Tomokazu Murakawa, Takahito Tamai +16 more
2023Nature Communications4 citations Open access
Semantic Scholar
Labile iron derived from autophagy-mediated ferritin degradation in cardiomyocytes under pressure overload increases myocardial oxidative stress and develops heart failure in mice
S. Omiya, Jumpei Ito, K. Otsu
20214 citations Open access
Semantic Scholar
Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes
S. Omiya, S. Hikoso, K. Otsu
20082 citations Open access
Semantic Scholar
Osteochondrogenic Transdifferentiation of Vascular Smooth Muscle Cells and Microenvironmental Dynamics in Medial Arterial Calcification
Y. Nakao, Tomohisa Sakaue, J. Ito, Mika Hamaguchi +13 more
2025bioRxiv1 citations Open access
Semantic Scholar
The I (cid:1) B Kinase (cid:2) /Nuclear Factor (cid:1) B Signaling Pathway Protects the Heart From Hemodynamic Stress Mediated by the Regulation of Manganese Superoxide Dismutase Expression
S. Hikoso, Osamu Yamaguchi, Yuko Nakano, Toshihiro Takeda +13 more
20091 citations
Semantic Scholar
Ferritinophagy maintains cardiac contractility through the regulation of mitochondrial function in cardiomyocytes
J. Ito, Kinya Otsu, S. Omiya
2026Journal of Molecular and Cellular Cardiology Plus0 citations Open access
Semantic Scholar
Oxidized mitochondrial DNA-dependent inflammasome in cardiac fibroblasts induces cardiac dysfunction
S. Omiya, Y. Tanada, J. Ito, Kinya Otsu
2026Journal of Molecular and Cellular Cardiology Plus0 citations Open access
Semantic Scholar
Rubicon-regulated beta-1 adrenergic receptor recycling protects the heart from pressure overload
Y. Akazawa, Manabu Taneike, Hiromichi Ueda, Rika Kitazume-Taneike +12 more
2022Scientific Reports0 citations Open access
Semantic Scholar
Author response: Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice
Jumpei Ito, S. Omiya, Mara Rusu, Hiromichi Ueda +9 more
20200 citations Open access
Semantic Scholar
Regnase-1, a ribonuclease, in cardiomyocytes regulates immune responses in the heart
S. Omiya, K. Otsu
2018Journal of Molecular and Cellular Cardiology0 citations
Semantic Scholar
Abstract 17796: Toll-like Receptor 9 Signaling Pathway Ameliorates Cardiac Rupture After Myocardial Infarction by Promoting the Proliferation of Myofibroblasts
S. Omiya, Y. Omori, K. Nishida, Ajay M. Shah +1 more
2015Circulation0 citations
Semantic Scholar
NO REFLOW PHENOMENON PREDICTS LEFT VENTRICULAR SYSTOLIC DYSFUNCTION BUT DOES NOT PREDICT LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN PATIENTS WITH REPERFUSED THEIR FIRST ACUTE MYOCARDIAL INFARCTION
S. Omiya, K. Iwakura, A. Okamura, K. Fujii
20120 citations Open access
Semantic Scholar
THE SEVERITY OF MYOCARDIAL DAMAGE CONTRIBUTES TO THE AUTONOMIC FUNCTION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
S. Omiya, K. Iwakura, A. Okamura, K. Fujii
20120 citations Open access
Semantic Scholar
IMPROVEMENT OF MITRAL REGURGITATION AFTER CATHETER ABLATION FOR ATRIAL FIBRILLATION
Y. Toyoshima, Koichi Inoue, R. Kimura, A. Doi +15 more
20120 citations Open access
Semantic Scholar
Abstract 14633: Longer Period of Atrial Fibrillation Persistence was Associated with Higher Prevalence of Triggers from the Non-Pulmonary Vein Foci
Koichi Inoue, R. Kimura, Y. Toyoshima, M. Masuda +14 more
20110 citations
Semantic Scholar
Abstract 9420: Detection Of No-Reflow Phenomenon by Three-Dimensional (3D) Myocardial Contrast Echocardiography in Patients with Acute Myocardial Infarction
K. Iwakura, A. Okamura, Y. Koyama, M. Date +13 more
2011Circulation0 citations
Semantic Scholar
MECHANISM OF IMPROVEMENT IN MITRAL REGURGITATION IN THE ACUTE PHASE AFTER CARDIAC RESYNCHRONIZATION THERAPY
M. Imai, K. Iwakura, A. Okamura, Y. Koyama +14 more
20100 citations Open access
Semantic Scholar
REVERSE REMODELING OF LEFT ATRIUM AFTER CATHETER ABLATION TO ATRIAL FIBRILLATION: ITS IMPACT ON LEFT VENTRICULAR FUNCTION AND RECURRENCE
Y. Toyoshima, Koichi Inoue, T. Kurotobi, R. Kimura +14 more
20100 citations Open access
Semantic Scholar
Abstract 2655: Elevated C-reactive Protein is Associated With Left Atrial Appendage Thrombus in Patients With Non-valvular Atrial Fibrillation
K. Iwakura, A. Okamura, T. Kurotobi, Y. Koyama +14 more
20090 citations
Semantic Scholar
Abstract 366: Evaluation of 2-Dimensional Strain and Strain Rate Predicts Myocardial Viability on the Early Stage of Acute Myocardial Infarction
Y. Toyoshima, K. Iwakura, A. Okamura, T. Kurotobi +14 more
20090 citations
Semantic Scholar
Abstract 197: Cardiac-specific Activation of Apoptosis Signal-regulating Kinase 1 Leads to Cardiac Dysfunction with Pathological Hypertrophy
Toshihiro Takeda, K. Otsu, Osamu Yamaguchi, Shinichi Hirotani +10 more
20070 citations
Semantic Scholar
the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice
T. Misaka, Tomokazu Murakawa, K. Nishida, Y. Omori +8 more
0 citations
Semantic Scholar

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K. Otsu×25
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K. Otsu — researcher profile on SciRah
K. Nishida×20
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Manabu Taneike×20
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Osamu Yamaguchi×18
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Osamu Yamaguchi — researcher profile on SciRah

Tomokazu Murakawa

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Y. Higuchi — researcher profile on SciRah

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K. Fujii — researcher profile on SciRah

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S. Hikoso — researcher profile on SciRah

Ajay M. Shah×10

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Toshihiro Takeda×9

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Y. Koyama — researcher profile on SciRah