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V. Bardwell · SciRah

Researcher profile · Semantic Scholar

V. Bardwell

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V. Bardwell — researcher profile on SciRah

h-index: 47
Works: 93
Citations: 9,404

Most-cited papers

The POZ domain: a conserved protein-protein interaction motif.
V. Bardwell, R. Treisman
1994Genes & Development782 citations Open access
Semantic Scholar
Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation.
C. S. Raymond, Mark W. Murphy, M. O'Sullivan, V. Bardwell +1 more
2000Genes & Development708 citations Open access
Semantic Scholar
DMRT1 prevents female reprogramming in the postnatal mammalian testis
Clinton K. Matson, Mark W. Murphy, A. Sarver, M. Griswold +2 more
2011Nature601 citations Open access
Semantic Scholar
Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development.
C. S. Raymond, Jae R. Kettlewell, B. Hirsch, V. Bardwell +1 more
1999Developmental Biology491 citations Open access
Semantic Scholar
BCoR, a novel corepressor involved in BCL-6 repression.
K. Huynh, W. Fischle, E. Verdin, V. Bardwell
2000Genes & Development489 citations Open access
Semantic Scholar
ETO, a Target of t(8;21) in Acute Leukemia, Interacts with the N-CoR and mSin3 Corepressors
B. Lutterbach, J. Westendorf, B. Linggi, Andrea Patten +9 more
1998Molecular and Cellular Biology465 citations Open access
Semantic Scholar
A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators.
C. S. Raymond, Emily D. Parker, Jae R. Kettlewell, L. Brown +8 more
1999Human Molecular Genetics370 citations
Semantic Scholar
Polycomb Group and SCF Ubiquitin Ligases Are Found in a Novel BCOR Complex That Is Recruited to BCL6 Targets
M. Gearhart, C. Corcoran, J. A. Wamstad, V. Bardwell
2006Molecular and Cellular Biology354 citations Open access
Semantic Scholar
The mammalian Doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells
Clinton K. Matson, Mark W. Murphy, M. Griswold, Shosei Yoshida +2 more
2010Developmental Cell344 citations Open access
Semantic Scholar
The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT
K. Huynh, V. Bardwell
1998Oncogene327 citations Open access
Semantic Scholar
Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR
David Ng, N. Thakker, C. Corcoran, D. Donnai +12 more
2004Nature Genetics323 citations
Semantic Scholar
Critical Residues within the BTB Domain of PLZF and Bcl-6 Modulate Interaction with Corepressors
A. Melnick, G. Carlile, K. Ahmad, C. Kiang +4 more
2002Molecular and Cellular Biology218 citations Open access
Semantic Scholar
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis
W. Béguelin, Matt Teater, M. Gearhart, María Teresa Calvo Fernández +15 more
2016Cancer Cell215 citations Open access
Semantic Scholar
The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency
Anthony D. Krentz, Mark W. Murphy, Shinseog Kim, Matthew S. Cook +9 more
2009Proceedings of the National Academy of Sciences of the United States of America196 citations Open access
Semantic Scholar
A hybrid mechanism of action for BCL6 in B-cells defined by formation of functionally distinct complexes at enhancers and promoters
K. Hatzi, Yan-Wen Jiang, Chuanxin Huang, F. Garrett-Bakelman +16 more
2013Cell Reports171 citations Open access
Semantic Scholar
Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation.
Shinseog Kim, V. Bardwell, D. Zarkower
2007Developmental Biology162 citations Open access
Semantic Scholar
Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer.
A. Ghetu, C. Corcoran, L. Cerchietti, V. Bardwell +2 more
2008Molecules and Cells161 citations Open access
Semantic Scholar
Evolutionary Dynamics of the DM Domain Gene Family in Metazoans
J. Volff, D. Zarkower, V. Bardwell, M. Schartl
2003Journal of Molecular Evolution143 citations
Semantic Scholar
Sexually dimorphic expression of multiple doublesex-related genes in the embryonic mouse gonad.
Shinseog Kim, Jae R. Kettlewell, Robert C Anderson, V. Bardwell +1 more
2003Gene Expression Patterns142 citations
Semantic Scholar
DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary
Anthony D. Krentz, Mark W. Murphy, A. Sarver, M. Griswold +2 more
2011Developmental Biology134 citations Open access
Semantic Scholar
Sexual cell fate reprogramming in the ovary by DMRT1
Robin E. Lindeman, M. Gearhart, A. Minkina, Anthony D. Krentz +2 more
2015Current Biology130 citations Open access
Semantic Scholar
Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis
Mark W. Murphy, A. Sarver, D. Rice, K. Hatzi +5 more
2010Proceedings of the National Academy of Sciences of the United States of America115 citations Open access
Semantic Scholar
Structure of the Polycomb Group protein PCGF1 (NSPC1) in complex with BCOR reveals basis for binding selectivity of PCGF homologs
Sarah E. Junco, Ren-Jing Wang, John C. Gaipa, A. B. Taylor +6 more
2013Structure109 citations Open access
Semantic Scholar
DMRT1 protects male gonadal cells from retinoid-dependent sexual transdifferentiation
A. Minkina, Clinton K. Matson, Robin E. Lindeman, N. Ghyselinck +2 more
2014Developmental Cell108 citations Open access
Semantic Scholar
DMRT1 Is Required for Mouse Spermatogonial Stem Cell Maintenance and Replenishment
Teng Zhang, J. Oatley, V. Bardwell, D. Zarkower
2016PLoS Genetics107 citations Open access
Semantic Scholar
An ancient protein-DNA interaction underlying metazoan sex determination
Mark W. Murphy, John K. Lee, S. Rojo, M. Gearhart +8 more
2015Nature Structural &Molecular Biology104 citations Open access
Semantic Scholar
Human Ccr4‐Not complex is a ligand‐dependent repressor of nuclear receptor‐mediated transcription
G. Winkler, K. Mulder, V. Bardwell, E. Kalkhoven +1 more
2006EMBO Journal102 citations Open access
Semantic Scholar
Role of the Transcriptional Corepressor Bcor in Embryonic Stem Cell Differentiation and Early Embryonic Development
J. A. Wamstad, C. Corcoran, Anne M. Keating, V. Bardwell
2008PLoS ONE99 citations Open access
Semantic Scholar
In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures
M. Rahmoun, R. Lavery, Sabine Laurent-Chaballier, N. Bellora +14 more
2017Nucleic Acids Research98 citations Open access
Semantic Scholar
The Polycomb‐associated protein Rybp is a ubiquitin binding protein
Rachele Arrigoni, S. L. Alam, Joseph A. Wamstad, V. Bardwell +2 more
2006FEBS Letters98 citations
Semantic Scholar
Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA
Mark W. Murphy, D. Zarkower, V. Bardwell
2007BMC Molecular Biology94 citations Open access
Semantic Scholar
A non-canonical BCOR-PRC1.1 complex represses differentiation programs in human ESCs
Zheng Wang, M. Gearhart, Yu-Wei Lee, Ishan Kumar +11 more
2018Cell Stem Cell90 citations Open access
Semantic Scholar
The ETO Protein of t ( 8 ; 21 ) AML is a Corepressor for the Bcl-6 B-cell Lymphoma Oncoprotein
N. Chevallier, C. Corcoran, Christine Lennon, Elizabeth Haijek +4 more
200388 citations
Semantic Scholar
BCOR regulates myeloid cell proliferation and differentiation
Qi-yuan Cao, M. Gearhart, S. Gery, Seyedmehdi Shojaee +14 more
2016Leukemia84 citations Open access
Semantic Scholar
Purification of RNA and RNA-protein complexes by an R17 coat protein affinity method.
V. Bardwell, M. Wickens
1990Nucleic Acids Research80 citations Open access
Semantic Scholar
The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis
Teng Zhang, Mark W. Murphy, M. Gearhart, V. Bardwell +1 more
2014Development73 citations Open access
Semantic Scholar
Mice Mutant in the DM Domain Gene Dmrt4 Are Viable and Fertile but Have Polyovular Follicles
J. Balciuniene, V. Bardwell, D. Zarkower
2006Molecular and Cellular Biology71 citations Open access
Semantic Scholar
A Mammal-Specific Doublesex Homolog Associates with Male Sex Chromatin and Is Required for Male Meiosis
Shinseog Kim, S. Namekawa, L. Niswander, Jeremy O. Ward +3 more
2007PLoS Genetics70 citations Open access
Semantic Scholar
A DM domain protein from a coral, Acropora millepora, homologous to proteins important for sex determination
Steven W. Miller, D. Hayward, T. Bunch, David J. Miller +4 more
2003Evolution & Development69 citations
Semantic Scholar
KDM2B recruitment of the Polycomb group complex, PRC1.1, requires cooperation between PCGF1 and BCORL1
Sarah J. Wong, M. Gearhart, A. B. Taylor, David R. Nanyes +8 more
2016Structure61 citations Open access
Semantic Scholar
mRNA Expression Analysis and the Molecular Basis of Neonatal Testis Defects in Dmrt1 Mutant Mice
U. Fahrioglu, Mark W. Murphy, D. Zarkower, V. Bardwell
2006Sexual Development59 citations Open access
Semantic Scholar
Site-directed ribose methylation identifies 2'-OH groups in polyadenylation substrates critical for AAUAAA recognition and poly(A) addition.
V. Bardwell, M. Wickens, S. Bienroth, W. Keller +2 more
1991Cell58 citations
Semantic Scholar
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis
M. Kelly, J. So, A. Rogers, G. Gregory +7 more
2019Nature Communications57 citations Open access
Semantic Scholar
Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line
Anthony D. Krentz, Mark W. Murphy, Teng Zhang, A. Sarver +4 more
2013Developmental Biology55 citations Open access
Semantic Scholar
The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming
Robin E. Lindeman, Mark W. Murphy, Kellie S Agrimson, Rachel L Gewiss +3 more
2021Nucleic Acids Research50 citations Open access
Semantic Scholar
The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis
Giorgio Oliviero, Nayla Munawar, Ariane Watson, G. Streubel +4 more
2015Scientific Reports50 citations Open access
Semantic Scholar
Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome.
Shiro Tara, Yusuke Isshiki, Yaeko Nakajima-Takagi, M. Oshima +11 more
2018Blood49 citations Open access
Semantic Scholar
Characterization of Bcor expression in mouse development.
J. A. Wamstad, V. Bardwell
2007Gene Expression Patterns44 citations Open access
Semantic Scholar
The enzyme that adds poly(A) to mRNAs is a classical poly(A) polymerase
V. Bardwell, D. Zarkower, M. Edmonds, Marvin Wickens
1990Molecular and Cellular Biology43 citations Open access
Semantic Scholar
Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene
M. Lefebure, R. Tothill, E. Kruse, E. Hawkins +22 more
2017Nature Communications41 citations Open access
Semantic Scholar

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