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D. Kobelt · SciRah

Researcher profile · Semantic Scholar

D. Kobelt

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D. Kobelt — researcher profile on SciRah

h-index: 21
Works: 88
Citations: 1,620

Most-cited papers

Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer.
U. Sack, W. Walther, D. Scudiero, M. Selby +6 more
2011Journal of the National Cancer Institute203 citations Open access
Semantic Scholar
S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction
M. Dahlmann, D. Kobelt, W. Walther, Giridhar Mudduluru +1 more
2016Cancers92 citations Open access
Semantic Scholar
Pro-inflammatory TNF-α and IFN-γ Promote Tumor Growth and Metastasis via Induction of MACC1
D. Kobelt, Chenyu Zhang, Isabelle Ailish Clayton-Lucey, R. Glauben +3 more
2020Frontiers in Immunology84 citations Open access
Semantic Scholar
Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1
M. Juneja, D. Kobelt, W. Walther, Cynthia Voss +10 more
2017PLoS Biology84 citations Open access
Semantic Scholar
MACC1—the first decade of a key metastasis molecule from gene discovery to clinical translation
H. Radhakrishnan, W. Walther, Fabian Zincke, D. Kobelt +5 more
2018Cancer Metastasis Review70 citations
Semantic Scholar
SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival
F. Schmid, Q. Wang, Matthew R. Huska, Miguel Andrade +8 more
2016Oncogene69 citations Open access
Semantic Scholar
Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy
J. Pahle, Lutz Menzel, Nicole Niesler, D. Kobelt +3 more
2017BMC Cancer68 citations Open access
Semantic Scholar
Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors
W. Walther, S. Petkov, ON Kuvardina, J. Aumann +7 more
2011Gene Therapy66 citations
Semantic Scholar
Performance of High Quality Minicircle DNA for In Vitro and In Vivo Gene Transfer
D. Kobelt, M. Schleef, M. Schmeer, J. Aumann +2 more
2012Molecular Biotechnology64 citations
Semantic Scholar
Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors
Marta Holstein, Cristina Mesa-Núñez, Csaba Miskey, E. Almarza +16 more
2018Molecular Therapy62 citations Open access
Semantic Scholar
In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice
A. Pichorner, U. Sack, D. Kobelt, Inken Kelch +5 more
2012Clinical and Experimental Metastasis57 citations
Semantic Scholar
Quantification of mRNA Expression Using Single-Molecule Nanopore Sensing
Yana Rozevsky, T. Gilboa, Xander F. van Kooten, D. Kobelt +3 more
2020ACS Nano52 citations Open access
Semantic Scholar
Novel Jet-Injection Technology for Nonviral Intratumoral Gene Transfer in Patients with Melanoma and Breast Cancer
W. Walther, R. Siegel, D. Kobelt, T. Knösel +7 more
2008Clinical Cancer Research50 citations Open access
Semantic Scholar
Clinical relevance of circulating MACC1 and S100A4 transcripts for ovarian cancer
T. Link, J. Kuhlmann, D. Kobelt, P. Herrmann +6 more
2019Molecular Oncology44 citations Open access
Semantic Scholar
HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model
T. Nguyen-Hoai, D. Kobelt, O. Hohn, M. D. Vu +7 more
2012Oncoimmunology38 citations Open access
Semantic Scholar
Repositioning of drugs for intervention in tumor progression and metastasis: Old drugs for new targets.
Giridhar Mudduluru, W. Walther, D. Kobelt, M. Dahlmann +3 more
2016Drug resistance updates34 citations
Semantic Scholar
Chemosensitization by diverging modulation by short-term and long-term TNF-α action on ABCB1 expression and NF-κB signaling in colon cancer.
W. Walther, D. Kobelt, Lisa Bauer, J. Aumann +1 more
2015International Journal of Oncology29 citations Open access
Semantic Scholar
Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker
F. Schmid, M. Dahlmann, Hanna Röhrich, D. Kobelt +4 more
2022British Journal of Cancer28 citations Open access
Semantic Scholar
Nonviral jet-injection gene transfer for efficient in vivo cytosine deaminase suicide gene therapy of colon carcinoma.
W. Walther, U. Stein, I. Fichtner, D. Kobelt +3 more
2005Molecular Therapy26 citations Open access
Semantic Scholar
Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis
B. Kortüm, H. Radhakrishnan, Fabian Zincke, C. Sachse +7 more
2022Oncogene24 citations Open access
Semantic Scholar
Effective Oncoleaking Treatment of Pancreatic Cancer by Claudin-Targeted Suicide Gene Therapy with Clostridium perfringens Enterotoxin (CPE)
J. Pahle, D. Kobelt, J. Aumann, D. Behrens +5 more
2021Cancers23 citations Open access
Semantic Scholar
Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells
Nazli Güllü, D. Kobelt, H. Brim, S. Rahman +7 more
2020Cells21 citations Open access
Semantic Scholar
Real‐world evidence for preventive effects of statins on cancer incidence: A trans‐Atlantic analysis
B. Gohlke, Fabian Zincke, Andreas Eckert, D. Kobelt +12 more
2021medRxiv20 citations Open access
Semantic Scholar
Restoring Treatment Response in Colorectal Cancer Cells by Targeting MACC1-Dependent ABCB1 Expression in Combination Therapy
M. Dahlmann, R. Werner, B. Kortüm, D. Kobelt +2 more
2020Frontiers in Oncology20 citations Open access
Semantic Scholar
Combination of Wnt/β-Catenin Targets S100A4 and DKK1 Improves Prognosis of Human Colorectal Cancer
M. Dahlmann, A. Monks, E. Harris, D. Kobelt +8 more
2021Cancers17 citations Open access
Semantic Scholar
The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis
D. Kobelt, Daniel Perez-Hernandez, C. Fleuter, M. Dahlmann +9 more
2021Oncogene17 citations Open access
Semantic Scholar
MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma
T. Hohmann, Urszula Hohmann, M. R. Kolbe, M. Dahlmann +3 more
2020Cell Communication and Signaling17 citations Open access
Semantic Scholar
Preclinical study on combined chemo‐ and nonviral gene therapy for sensitization of melanoma using a human TNF‐alpha expressing MIDGE DNA vector
D. Kobelt, J. Aumann, M. Schmidt, B. Wittig +6 more
2014Molecular Oncology16 citations Open access
Semantic Scholar
Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases.
K. Brand, O. Bandapalli, C. Franke, D. Kobelt +9 more
2005International Journal of Cancer16 citations
Semantic Scholar
A Seven-Year Storage Report of Good Manufacturing Practice–Grade Naked Plasmid DNA: Stability, Topology, and In Vitro/In Vivo Functional Analysis
W. Walther, M. Schmeer, D. Kobelt, Ruth Baier +6 more
2013Human Gene Therapy Clinical Development15 citations
Semantic Scholar
Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells
Reza Haschemi, D. Kobelt, Elisabeth Steinwarz, Martin Schlesinger +2 more
2021International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
Application Route and Immune Status of the Host Determine Safety and Oncolytic Activity of Oncolytic Coxsackievirus B3 Variant PD-H
A. Hazini, B. Dieringer, K. Klingel, M. Pryshliak +6 more
2021Viruses13 citations Open access
Semantic Scholar
MACC1-Induced Collective Migration Is Promoted by Proliferation Rather Than Single Cell Biomechanics
T. Hohmann, Urszula Hohmann, M. Dahlmann, D. Kobelt +2 more
2022Cancers12 citations Open access
Semantic Scholar
Obesity, colorectal cancer and MACC1 expression: A possible novel molecular association
Ina Bähr, Lina Jaeschke, K. Nimptsch, J. Janke +5 more
2022International Journal of Oncology12 citations Open access
Semantic Scholar
S100A4 Is a Strong Negative Prognostic Marker and Potential Therapeutic Target in Adenocarcinoma of the Stomach and Esophagus
C. Treese, K. Hartl, M. Pötzsch, Matthias Dahlmann +9 more
2022Cells12 citations Open access
Semantic Scholar
Real-Time Cell Migration Monitoring to Analyze Drug Synergism in the Scratch Assay Using the IncuCyte System.
D. Kobelt, W. Walther, U. Stein
2021Methods in molecular biology11 citations
Semantic Scholar
Circulating MACC1 Transcripts in Glioblastoma Patients Predict Prognosis and Treatment Response
C. Hagemann, Nikolas Neuhaus, M. Dahlmann, A. Kessler +9 more
2019Cancers11 citations Open access
Semantic Scholar
The FeDiNAR Project: Using Augmented Reality to Turn Mistakes into Learning Opportunities
Alexander Atanasyan, D. Kobelt, Marvin Goppold, T. Cichon +1 more
202010 citations
Semantic Scholar
MACC1 revisited – an in-depth review of a master of metastasis
P. Schöpe, Sebastian Torke, D. Kobelt, B. Kortüm +5 more
2024Biomarker Research9 citations Open access
Semantic Scholar
MACC1 Regulates LGR5 to Promote Cancer Stem Cell Properties in Colorectal Cancer
M. Erdem, K. Lee, Markus S. Hardt, Joseph L. Regan +5 more
2024Cancers9 citations Open access
Semantic Scholar
Inhibition of MACC1-Induced Metastasis in Esophageal and Gastric Adenocarcinomas
C. Treese, Jessica Werchan, M. von Winterfeld, E. Berg +8 more
2022Cancers9 citations Open access
Semantic Scholar
Elevated MACC1 Expression in Colorectal Cancer Is Driven by Chromosomal Instability and Is Associated with Molecular Subtype and Worse Patient Survival
V. Vuaroqueaux, Alexandra Musch, D. Kobelt, T. Risch +6 more
2022Cancers9 citations Open access
Semantic Scholar
Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases
O. Bandapalli, Martina Geheeb, D. Kobelt, Katrin Kuehnle +9 more
20069 citations
Semantic Scholar
Systematic Identification of MACC1-Driven Metabolic Networks in Colorectal Cancer
J. Lisec, D. Kobelt, W. Walther, Margarita Mokrizkij +8 more
2021Cancers8 citations Open access
Semantic Scholar
Suicide nanoplasmids coding for ribosome-inactivating proteins.
Hardy Mitdank, Meike Tröger, A. Sonntag, Nima Amini Shirazi +5 more
2021European Journal of Pharmaceutical Sciences7 citations Open access
Semantic Scholar
Small Ones to Fight a Big Problem—Intervention of Cancer Metastasis by Small Molecules
D. Kobelt, M. Dahlmann, Malti Dumbani, Nazli Güllü +4 more
2020Cancers7 citations Open access
Semantic Scholar
Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis.
Shi-Xian Yan, P. Schöpe, Joe Lewis, K. Putzker +13 more
2023Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie6 citations Open access
Semantic Scholar
A Brief Introduction to Current Cancer Gene Therapy.
D. Kobelt, J. Pahle, W. Walther
2022Methods in molecular biology6 citations
Semantic Scholar
Claudin-Targeted Suicide Gene Therapy for Claudin-Overexpressing Tumor Cells by Using Modified Clostridium perfringens Enterotoxin (CPE).
Laura-Sophie Beier, J. Piontek, A. Piontek, J. Protze +2 more
2022Methods in molecular biology5 citations
Semantic Scholar
Intratumoral dispersion, retention, systemic biodistribution, and clearance of a small-size tumor necrosis factor-α-expressing MIDGE vector after nonviral in vivo jet-injection gene transfer.
Nele R. Galling, D. Kobelt, J. Aumann, M. Schmidt +3 more
2012Human Gene Therapy Methods5 citations
Semantic Scholar

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