Researcher profile · Semantic Scholar

Vincent Zecchini

h-index: 19
Works: 37
Citations: 3,502

Most-cited papers

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
C. Massie, A. Lynch, A. Ramos-Montoya, J. Boren +22 more
2011EMBO Journal638 citations Open access
Semantic Scholar
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M. Sciacovelli, E. Gonçalves, T. I. Johnson, Vincent Zecchini +20 more
2016Nature538 citations Open access
Semantic Scholar
The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man.
N. Sharma, C. Massie, A. Ramos-Montoya, Vincent Zecchini +7 more
2013Cancer Cell407 citations Open access
Semantic Scholar
Fumarate induces vesicular release of mtDNA to drive innate immunity
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle J. E. Janssen +23 more
2023Nature306 citations Open access
Semantic Scholar
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer
M. Asim, F. Tarish, H. Zecchini, K. Sanjiv +26 more
2017Nature Communications271 citations Open access
Semantic Scholar
CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?
A. M. Arias, Vincent Zecchini, Keith Brennan
2002Current Opinion in Genetics and Development244 citations
Semantic Scholar
Targeting fumarate hydratase promotes mitochondrial RNA-mediated interferon production
A. Hooftman, Christian G. Peace, D. Ryan, Emily A. Day +24 more
2023Nature210 citations Open access
Semantic Scholar
Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target
M. Asim, C. Massie, F. Orafidiya, N. Pértega-Gomes +36 more
2015Journal of the National Cancer Institute181 citations Open access
Semantic Scholar
An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila.
Vincent Zecchini, Keith Brennan, A. Martinez-Arias
1999Current Biology130 citations Open access
Semantic Scholar
Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells.
Vincent Zecchini, Renae Domaschenz, D. Winton, Phil Jones
2005Genes & Development128 citations Open access
Semantic Scholar
The abruptex mutations of notch disrupt the establishment of proneural clusters in Drosophila.
Keith Brennan, R. Tateson, T. Lieber, J. Couso +2 more
1999Developmental Biology72 citations Open access
Semantic Scholar
Metabolic synthetic lethality in cancer therapy.
Vincent Zecchini, C. Frezza
2017Biochimica et Biophysica Acta - Bioenergetics62 citations Open access
Semantic Scholar
Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer
Vincent Zecchini, B. Madhu, R. Russell, N. Pértega-Gomes +15 more
2014EMBO Journal60 citations Open access
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
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Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues
M. Kamp, J. Surmacki, Marc Segarra-Mondejar, T. Young +6 more
2023bioRxiv39 citations Open access
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Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression
M. Sciacovelli, Aurélien J. F. Dugourd, L. V. Jimenez, Ming Yang +24 more
2022Nature Communications38 citations Open access
Semantic Scholar
Notch receptor encodes two structurally separable functions in Drosophila: A genetic analysis
T. Langdon, P. Hayward, Keith Brennan, Frederik Wirtz-Peitz +5 more
2006Developmental Dynamics26 citations Open access
Semantic Scholar
Nuclear Trafficking and Functions of Endocytic Proteins Implicated in Oncogenesis
J. Borlido, Vincent Zecchini, Ian G. Mills
2009Traffic : the International Journal of Intracellular Transport24 citations
Semantic Scholar
A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer
A. Warren, C. Massie, Kate Watt, Katarina Luko +23 more
2018Oncogene21 citations Open access
Semantic Scholar
Loss of hSef promotes metastasis through upregulation of EMT in prostate cancer
S. Hori, K. Wadhwa, V. Pisupati, Vincent Zecchini +4 more
2017International Journal of Cancer16 citations Open access
Semantic Scholar
Corrigendum: Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M. Sciacovelli, E. Gonçalves, T. I. Johnson, Vincent Zecchini +20 more
2016Nature13 citations Open access
Semantic Scholar
Putting chromatin immunoprecipitation into context
Vincent Zecchini, Ian G. Mills
2009Journal of Cellular Biochemistry13 citations
Semantic Scholar
Intestinal Activation of Notch Signaling Induces Rapid Onset Hepatic Steatosis and Insulin Resistance
Joanna C. Fowler, Vincent Zecchini, Philip H. Jones
2011PLoS ONE12 citations Open access
Semantic Scholar
Nitrogen partitioning between branched-chain amino acids and urea cycle enzymes sustains renal cancer progression
M. Sciacovelli, Aurélien J. F. Dugourd, L. V. Jimenez, Ming Yang +24 more
2021bioRxiv4 citations Open access
Semantic Scholar
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition (vol 537, pg 544, 2016)
M. Sciacovelli, E. Gonçalves, T. I. Johnson, Vincent Zecchini +20 more
20163 citations
Semantic Scholar
Targeting the pro‐survival side‐effects of androgen‐deprivation therapy in prostate cancer
Vincent Zecchini, D. Neal
2013BJU International3 citations Open access
Semantic Scholar
A new inducible mouse model of FH loss.
Vincent Zecchini, Chrysanthi Moschandrea, Farina Schneider, C. Frezza
2026Methods in Cell Biology0 citations
Semantic Scholar
Chemical imaging reveals metabolite distribution in tissues using Raman microspectroscopy
Chun-Chin Wang, Seema Bachoo, Ellie V. Bunce, Mariam-Eleni Oraiopoulou +9 more
2025Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXIII0 citations
Semantic Scholar
Raman micro-spectroscopy reveals the spatial distribution of fumarate in living cells (Conference Presentation)
M. Kamp, J. Surmacki, Vincent Zecchini, K. Chrabąszcz +4 more
2023Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXI0 citations
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Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer
Mohammad Asim, F. Tarish, H. Zecchini, K. Sanjiv +26 more
2017Nature Communications0 citations Open access
Semantic Scholar
Abstract LB-003: Androgen-regulated proteome reveals a therapeutically relevant androgen receptor coactivator target in prostate cancer
M. Asim, C. Massie, A. Warren, Katarina Luko +21 more
20160 citations
Semantic Scholar
Abstract LB-176: The human androgen receptor regulates DNA damage response (DDR) in prostate cancer
M. Asim, H. Zecchini, F. Tarish, C. Massie +22 more
20160 citations
Semantic Scholar
Fumarate is an epigenetic modifier that elicits epithelial-to-1 mesenchymal transition 2
M. Sciacovelli, E. Gonçalves, T. I. Johnson, Vincent Zecchini +24 more
20160 citations
Semantic Scholar
283 Similar expression to FGF (Sef) is an important determinant of the prostate cancer cells' ability to metastasise in vivo
S. Hori, K. Wadhwa, A. Ramos-Montoya, Vincent Zecchini +3 more
20150 citations
Semantic Scholar
Supplementary figure 6 Asim et al
M. Asim, C. Massie, F. Orafidiya, N. Pértega-Gomes +36 more
20150 citations
Semantic Scholar
Abstract B133: Regulation of the androgen receptor function by a metabolic kinase in prostate cancer.
M. Asim, C. Massie, H. Zecchini, A. Baridi +18 more
20130 citations
Semantic Scholar
Abstract 1714: Transcriptional networks downstream of the AR identify clinically relevant prostate cancer targets
C. Massie, A. Lynch, R. Stark, A. Ramos-Montoya +18 more
20100 citations
Semantic Scholar

C. Frezza

×12

A. Lynch×8

M. Asim×8

A. Baridi×8

A. Baniahmad×8

R. Stark×7

P. Rennie×7

M. Sciacovelli×6