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N. Vad · SciRah

Researcher profile · Semantic Scholar

N. Vad

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N. Vad — researcher profile on SciRah

h-index: 11
Works: 38
Citations: 505

Most-cited papers

Pharmacologic screens reveal metformin that suppresses GRP78-dependent autophagy to enhance the anti-myeloma effect of bortezomib
S. Jagannathan, May Abdel-Malek, E. Malek, N. Vad +3 more
2015Leukemia108 citations Open access
Semantic Scholar
MiR-29b replacement inhibits proteasomes and disrupts aggresome+autophagosome formation to enhance the antimyeloma benefit of bortezomib
S. Jagannathan, N. Vad, S. Vallabhapurapu, K. C. Anderson +1 more
2014Leukemia78 citations Open access
Semantic Scholar
Efficacy of Caffeic Acid Phenethyl Ester (CAPE) in skin B16-F0 melanoma tumor bearing C57BL/6 mice
Shashi K. Kudugunti, N. Vad, Ehi Ekogbo, M. Moridani
2011Investigational new drugs60 citations
Semantic Scholar
Pharmacogenomics and chemical library screens reveal a novel SCFSKP2 inhibitor that overcomes Bortezomib resistance in multiple myeloma
E. Malek, May Abdel-Malek, S. Jagannathan, N. Vad +8 more
2016Leukemia59 citations Open access
Semantic Scholar
Biochemical mechanism of Caffeic Acid Phenylethyl Ester (CAPE) selective toxicity towards melanoma cell lines
Shashi K. Kudugunti, N. Vad, Amanda J Whiteside, Bhakti U. Naik +3 more
2010Chemico-Biological Interactions53 citations Open access
Semantic Scholar
Biochemical mechanism of Acetaminophen (APAP) induced toxicity in melanoma cell lines
N. Vad, Garret Yount, Dan H. Moore, J. Weidanz +1 more
2009Journal of Pharmacy and Science38 citations Open access
Semantic Scholar
Biochemical mechanism of acetylsalicylic acid (Aspirin) selective toxicity toward melanoma cell lines
N. Vad, Garret Yount, M. Moridani
2008Melanoma research29 citations
Semantic Scholar
Efficacy of acetylsalicylic acid (aspirin) in skin B16-F0 melanoma tumor-bearing C57BL/6 mice
N. Vad, Shashi K. Kudugunti, Hezhen Wang, G. Bhat +1 more
2014Tumor Biology24 citations
Semantic Scholar
Structure-toxicity relationship of phenolic analogs as anti-melanoma agents: An enzyme directed prodrug approach
N. Vad, Prabodh K. Kandala, S. Srivastava, M. Moridani
2009Chemico-Biological Interactions14 citations Open access
Semantic Scholar
Efficacy of acetaminophen in skin B16-F0 melanoma tumor-bearing C57BL/6 mice.
N. Vad, Shashi K. Kudugunti, D. Graber, N. Bailey +2 more
2009International Journal of Oncology14 citations Open access
Semantic Scholar
Metabolic bioactivation and toxicity of ethyl 4-hydroxybenzoate in human SK-MEL-28 melanoma cells.
N. Vad, Imam H. Shaik, R. Mehvar, M. Moridani
2008Journal of Pharmacy and Science14 citations
Semantic Scholar
MiR-29 b replacement inhibits proteasomes and disrupts aggresome + autophagosome formation to enhance the antimyeloma bene fi t of bortezomib
S. Jagannathan, N. Vad, S. Vallabhapurapu, K. Anderson +1 more
20157 citations
Semantic Scholar
Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101
Alexander Scholz, J. Defalco, Yvonne Leung, I. Aydin +28 more
2022Proceedings of the National Academy of Sciences of the United States of America2 citations Open access
Semantic Scholar
Abstract 153: Long non-coding RNAs deregulated in Multiple Myeloma impact therapeutic response to proteasome inhibitors
E. Malek, R. Karns, A. Jegga, S. Jagannathan +3 more
20151 citations
Semantic Scholar
Abstract 4242: Metformin suppresses GRP78-dependent PI3-Kinase activity in clonogenic side population to enhance the anti-myeloma benefit of bortezomib
James J. Driscoll, S. Jagannathan, M. Abdelmalek, N. Vad +1 more
20151 citations
Semantic Scholar
TM-03THE HSP90 INHIBITOR GANETESPIB IS AN EFFECTIVE THERAPY FOR GLIOBLASTOMA THAT BLOCKS EGFR-DRIVEN TUMOR GROWTH
James J. Driscoll, N. Vad, S. Jagannathan
20141 citations Open access
Semantic Scholar
SC-31RATIONAL DESIGN OF A PI3-KINASE/mTOR INHIBITOR CYTOTOXIC TO BRAIN CANCER STEM CELLS UNDER HYPOXIA
N. Vad, S. Jagannathan, K. Sumita, M. Abdelmalek +1 more
20141 citations Open access
Semantic Scholar
Abstract 1709: Molecular inhibition of autophagy enhances dihydroceramides-induced cell death in glioblastoma multiforme cell lines.
N. Vad, Dong Wang, B. Maurer
20131 citations
Semantic Scholar
Pilot Study on a Far Infrared Ray Emitting Compression Knee Sleeve for Symptom Relief in Knee Osteoarthritis
S. Balkaran, Hannah Asirvatham, N. Vad, Shomaiya Alam +5 more
2025The Open Orthopaedics Journal0 citations Open access
Semantic Scholar
Prevalence of Bone Edema-like Lesions in Patients with Knee Osteoarthritis
David A. Kolin, Antonio Madrazo-Ibarra, Hersh Patel, Arda Dalkir +5 more
2023Journal of Orthopaedics and Sports Medicine0 citations Open access
Semantic Scholar
1194 Discovery and pre-clinical development of a novel and differentiated EphA2-targeted antibody in multiple bispecific formats
Maryam M. Bhatti, Michael D. Weiss, Amanda R. Haltom, J. Finn +14 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
559 Preclinical evaluation of pegylated liposomal Doxorubicin or Doxorubicin with mATRC-101 in the EMT6 syngeneic mouse model
Danhui Zhang, N. Vad, E. Wechsler
2021Journal for ImmunoTherapy of Cancer0 citations Open access
Semantic Scholar
689 ATRC-101 Drives Potent Single-Agent Activity in Mouse Syngeneic Tumor Models via a Novel Cellular Mechanism of Action
Yvonne Leung, N. Vad, Anne Ye, Daniel Santos +24 more
20200 citations Open access
Semantic Scholar
469 Cooperation between checkpoint inhibitors targeting the PD-1/PD-L1 axis and ATRC-101, a novel clinical-stage candidate for the treatment of solid tissue malignancies
Amy B. Manning-Boğ, J. Defalco, Alexander Scholz, I. Aydin +21 more
20200 citations Open access
Semantic Scholar
Abstract 2885: Dihydroceramide increase precedes golgi dispersal, pro-survival autophagy, ER stress, and UPR in fenretinide + safingol treated neuroblastoma cells
N. Vad, Dong Wang, Hwangeui Cho, Dattesh Verlekar +4 more
2018Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 1057: Co-treatment with fenretinide and safingol induced p38 MAPK and/or FOXO3a activated pro-survival autophagy in glioblastoma multiforme cells
N. Vad, Dong Wang, Charles A. Linch, B. Maurer
20170 citations
Semantic Scholar
Abstract 4656: ER stress, unfolded protein response, and autophagy are pro-survival responses to fenretinide + safingol treatment in GBM cells
N. Vad, Dong Wang, B. Maurer
20160 citations
Semantic Scholar
Abstract A18: MicroRNA-29b replacement inhibits proteasomes and disrupts the aggresome-autophagy pathway to enhance the antimyeloma benefit of bortezomib.
S. Jagannathan, N. Vad, M. Abdelmalek, E. Malek +1 more
20150 citations
Semantic Scholar
Correlation of Non-Coding RNA Expression with Response to Proteasome Inhibitors in Multiple Myeloma
E. Malek, T. Latif, A. Jegga, S. Jagannathan +3 more
20140 citations
Semantic Scholar
Microrna-29b Targets PSME4 to Inhibit Proteasome Activity and Prevent the Delivery of Aggresomes to Autophagosomes for Anti-Myeloma Benefit
S. Jagannathan, N. Vad, M. Abdelmalek, E. Malek +1 more
20140 citations
Semantic Scholar
Novel Therapeutic Strategies to Target Protein Quality Control Compartments in Multiple Myeloma
M. Abdelmalek, S. Jagannathan, E. Malek, N. Vad +5 more
20140 citations
Semantic Scholar
Metformin Suppresses the GRP78-Dependent Delivery of Aggresomes to Autophagosomes to Enhance the Anti-Myeloma Benefit of Proteasome Inhibition
S. Jagannathan, N. Vad, M. Abdelmalek, E. Malek +1 more
20140 citations
Semantic Scholar
Abstract 1345: Bioactivation of luteolin as a prodrug by tyrosinase inhibits human glutathione S-transferase and induces toxicity in SK-MEL-28 melanoma cells
R. Balyan, Shashi K. Kudugunti, N. Vad, M. Moridani
20110 citations
Semantic Scholar
Abstract #660: In-vitro and in-vivo investigation of Caffeic acid Phenyl Ethyl Ester (CAPE) prodrug as an anti-melanoma agent
Shashi K. Kudugunti, N. Vad, M. Moridani
20090 citations
Semantic Scholar
Tyrosinase activation of acetylsalicylic acid (Aspirin) leads to acetylsalicylic acid selective toxicity towards melanocytic melanoma cell lines
N. Vad, Garret Yount, M. Moridani
20080 citations
Semantic Scholar
Biochemical mechanism of acetaminophen (APAP) toxicity in human melanocytic melanoma cell lines: a tyrosinase produrg activation approach
N. Vad, Garret Yount, Dan H. Moore, Tiffany Nguyen +2 more
20080 citations
Semantic Scholar
Ethyl 4-hydroxybenzoate toxicity towards human SK-MEL-28 melanoma cell line involves mitochondrial toxicity, intracellular GSH depletion, quinone and reactive oxygen species formation
N. Vad, Imam H. Shaik, R. Mehvar, M. Moridani
20070 citations
Semantic Scholar
Curcumin induced toxicity towards human SK-MEL-28 melanoma cells
N. Vad, M. Moridani
20070 citations
Semantic Scholar

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