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S. Lippow · SciRah

Researcher profile · Semantic Scholar

S. Lippow

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S. Lippow — researcher profile on SciRah

h-index: 12
Works: 28
Citations: 2,116

Most-cited papers

Isolating and engineering human antibodies using yeast surface display
G. Chao, Wai L. Lau, B. Hackel, Stephen L. Sazinsky +2 more
2006Nature Protocols933 citations
Semantic Scholar
Computational design of antibody-affinity improvement beyond in vivo maturation
S. Lippow, K. Wittrup, B. Tidor
2007Nature Biotechnology363 citations Open access
Semantic Scholar
Progress in computational protein design.
S. Lippow, B. Tidor
2007Current Opinion in Biotechnology203 citations Open access
Semantic Scholar
Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody.
K. Midelfort, H. H. Hernandez, S. Lippow, Bruce Tidor +2 more
2004Journal of Molecular Biology140 citations
Semantic Scholar
Evolution of an interloop disulfide bond in high-affinity antibody mimics based on fibronectin type III domain and selected by yeast surface display: molecular convergence with single-domain camelid and shark antibodies.
D. Lipovšek, S. Lippow, B. Hackel, Melissa W. Gregson +3 more
2007Journal of Molecular Biology109 citations
Semantic Scholar
Improved mutants from directed evolution are biased to orthologous substitutions.
Jennifer R. Cochran, Yong-Sung Kim, S. Lippow, B. Rao +1 more
2006Protein engineering, design & selection : PEDS65 citations
Semantic Scholar
Engineering enzyme specificity using computational design of a defined-sequence library.
S. Lippow, T. Moon, Subhayu Basu, Sang-Hwal Yoon +5 more
2010Chemistry and Biology56 citations Open access
Semantic Scholar
A candidate antibody drug for prevention of malaria
Katherine L Williams, Steve Guerrero, Yevel Flores-Garcia, Dongkyoon Kim +26 more
2024Nature Medicine54 citations Open access
Semantic Scholar
Pairwise selection assembly for sequence-independent construction of long-length DNA
William J. Blake, B. Chapman, Anuradha Zindal, Michael E. Lee +2 more
2010Nucleic Acids Research52 citations Open access
Semantic Scholar
Numerical integration techniques for curved-element discretizations of molecule-solvent interfaces.
J. Bardhan, M. Altman, David J. Willis, S. Lippow +2 more
2007Journal of Chemical Physics46 citations Open access
Semantic Scholar
Creation of a type IIS restriction endonuclease with a long recognition sequence
S. Lippow, P. Aha, M. Parker, William J. Blake +2 more
2009Nucleic Acids Research32 citations Open access
Semantic Scholar
Rotamer Optimization for Protein Design through MAP Estimation and Problem-Size Reduction
Eun-Jong Hong, S. Lippow, B. Tidor, Tomas Lozano-Perez
2009Journal of Computational Chemistry22 citations Open access
Semantic Scholar
Exploring New Frontiers in LAG-3 Biology and Therapeutics
Jun Wang, C. Klein, Jennifer R. Cochran, Jonathan T. Sockolosky +1 more
2025TIPS - Trends in Pharmacological Sciences11 citations Open access
Semantic Scholar
Long-Acting IL-33 Mobilizes High-Quality Hematopoietic Stem and Progenitor Cells More Efficiently Than Granulocyte Colony-Stimulating Factor or AMD3100.
Carsten Alt, Shu-Jun Yuan, Fa-Ye Wu, Basha Stankovich +9 more
2019Biology of Blood and Marrow Transplantation9 citations Open access
Semantic Scholar
Effect of tacticity on the segmental dynamics of polypropylene melts investigated by 13C nuclear magnetic resonance
S. Lippow, Xiaohua Qiu, M. Ediger
20018 citations
Semantic Scholar
Library Construction For Protein Engineering
Daa Lipovek, B. Baynes, Subhayu Basu, Marco A. Mena +1 more
20097 citations
Semantic Scholar
A Curved Panel Integration Technique for Molecular Surfaces
J. Bardhan, M. Altman, S. Lippow, B. Tidor +1 more
20055 citations
Semantic Scholar
Chao, G. et al. Isolating and engineering human antibodies using yeast surface display. Nat. Protoc. 1, 755-768
G. Chao, Wai L. Lau, K. Wittrup, B. Hackel +2 more
20063 citations
Semantic Scholar
Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101
Alexander Scholz, J. Defalco, Yvonne Leung, I. Aydin +28 more
2022Proceedings of the National Academy of Sciences of the United States of America2 citations Open access
Semantic Scholar
Abstract CT203: First-in-human phase 1b study of ATRC-101, a patient-derived antibody with a tumor-specific target, as monotherapy or in combination with pembrolizumab, in patients with solid tumors
J. Benjamin, N. Higgins, C. Millward, J. Defalco +14 more
2021Clinical Trials1 citations
Semantic Scholar
First-in-human phase Ib study of ATRC-101, an engineered version of a patient-derived antibody targeting a tumor-restricted ribonucleoprotein complex.
J. Benjamin, N. Higgins, C. Millward, J. Defalco +14 more
20201 citations
Semantic Scholar
1194 Discovery and pre-clinical development of a novel and differentiated EphA2-targeted antibody in multiple bispecific formats
Maryam M. Bhatti, Michael D. Weiss, Amanda R. Haltom, J. Finn +14 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
689 ATRC-101 Drives Potent Single-Agent Activity in Mouse Syngeneic Tumor Models via a Novel Cellular Mechanism of Action
Yvonne Leung, N. Vad, Anne Ye, Daniel Santos +24 more
20200 citations Open access
Semantic Scholar
469 Cooperation between checkpoint inhibitors targeting the PD-1/PD-L1 axis and ATRC-101, a novel clinical-stage candidate for the treatment of solid tissue malignancies
Amy B. Manning-Boğ, J. Defalco, Alexander Scholz, I. Aydin +21 more
20200 citations Open access
Semantic Scholar
Computational Analysis, Design, and Experimental Validation of Antibody Binding Anity Improvements Beyond In Vivo Maturation
S. Lippow
20070 citations
Semantic Scholar
4m5.3 anti-fluorescein single chain antibody fragment (scFv)
K. Midelfort, H. Hernández, S. Lippow, B. Tidor +2 more
20050 citations
Semantic Scholar
Re-Design of Protein Interfaces : Co-Optimization of Packing and Electrostatic Interactions
Karl J. M. Hanf, B. Joughin, S. Lippow, A. Senes
20020 citations
Semantic Scholar
MIT Open Access Articles Engineering Enzyme Specificity Using Computational Design of a Defined-Sequence Library
S. Lippow, Tae Seok Moon, Subhayu Basu, Sang-Hwal Yoon +5 more
0 citations
Semantic Scholar

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