Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

A. Zavacki · SciRah

Researcher profile · Semantic Scholar

A. Zavacki

Share profile

A. Zavacki — researcher profile on SciRah

h-index: 40
Works: 81
Citations: 9,146

Most-cited papers

Bile acids: natural ligands for an orphan nuclear receptor.
D. Parks, S. Blanchard, R. Bledsoe, Gyan Chandra +7 more
1999Science2,266 citations
Semantic Scholar
Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1 Null Mice
Pei-Hsuan Wu, Paul T. Tarr, K. Lindenberg, J. St-Pierre +17 more
20041,198 citations
Semantic Scholar
Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling.
B. Gereben, A. Zavacki, S. Ribich, Brian W. Kim +4 more
2008Endocrine reviews845 citations Open access
Semantic Scholar
Thyroid hormones and skeletal muscle — new insights and potential implications
D. Salvatore, W. Simonides, M. Dentice, A. Zavacki +1 more
2013Nature Reviews Endocrinology365 citations Open access
Semantic Scholar
LXRs regulate the balance between fat storage and oxidation.
N. Kalaany, K. Gauthier, A. Zavacki, P. Mammen +6 more
2005Cell Metabolism323 citations Open access
Semantic Scholar
Identification of the DNA Binding Specificity and Potential Target Genes for the Farnesoid X-activated Receptor*
B. Laffitte, H. R. Kast, Catherine M. Nguyen, A. Zavacki +2 more
2000Journal of Biological Chemistry285 citations Open access
Semantic Scholar
The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate
M. Dentice, Amitabha Bandyopadhyay, B. Gereben, I. Callebaut +12 more
2005Nature Cell Biology225 citations Open access
Semantic Scholar
Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes
M. Dentice, C. Luongo, Stephen A. Huang, R. Ambrosio +11 more
2007Proceedings of the National Academy of Sciences of the United States of America180 citations Open access
Semantic Scholar
Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.
Beatriz C. G. Freitas, B. Gereben, Melany Castillo, I. Kalló +10 more
2010Journal of Clinical Investigation167 citations Open access
Semantic Scholar
Thyroid Hormone Promotes Postnatal Rat Pancreatic β-Cell Development and Glucose-Responsive Insulin Secretion Through MAFA
Cristina Aguayo-Mazzucato, A. Zavacki, Alejandra Marinelarena, J. Hollister-Lock +6 more
2013Diabetes148 citations Open access
Semantic Scholar
Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse.
A. Zavacki, H. Ying, M. Christoffolete, G. Aerts +5 more
2005Endocrinology146 citations
Semantic Scholar
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.
Jian-Die D. Lin, Pei-Hsuan Wu, Paul T. Tarr, Katrin S. Lindenberg +19 more
2004Cell146 citations Open access
Semantic Scholar
A novel retinoid X receptor-independent thyroid hormone response element is present in the human type 1 deiodinase gene
N. Toyoda, A. Zavacki, A. L. Maia, J. Harney +1 more
1995Molecular and Cellular Biology146 citations Open access
Semantic Scholar
Protein discharge from immature secretory granules displays both regulated and constitutive characteristics.
P. Arvan, Regina Kuliawat, D. Prabakaran, A. Zavacki +3 more
1991Journal of Biological Chemistry142 citations Open access
Semantic Scholar
The deiodinases and the control of intracellular thyroid hormone signaling during cellular differentiation
M. Dentice, A. Marsili, A. Zavacki, P. R. Larsen +1 more
2012Biochimica et Biophysica Acta136 citations Open access
Semantic Scholar
Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation.
Cyntia Curcio-Morelli, A. Zavacki, Marcelo Christofollete, B. Gereben +5 more
2003Journal of Clinical Investigation132 citations Open access
Semantic Scholar
The Arrestin Domain Containing 3 (ARRDC3) Protein Regulates Body Mass and Energy Expenditure
P. Patwari, V. Emilsson, E. Schadt, William A. Chutkow +10 more
2011Cell Metabolism125 citations Open access
Semantic Scholar
The role of the iodothyronine deiodinases in the physiology and pathophysiology of thyroid hormone action
P. R. Larsen, A. Zavacki
2012European Thyroid Journal115 citations Open access
Semantic Scholar
Mice with a Targeted Deletion of the Type 2 Deiodinase Are Insulin Resistant and Susceptible to Diet Induced Obesity
A. Marsili, Cristina Aguayo-Mazzucato, Ting Chen, Aditi Kumar +11 more
2011PLoS ONE109 citations Open access
Semantic Scholar
Ubiquitination-Induced Conformational Change within the Deiodinase Dimer Is a Switch Regulating Enzyme Activity
G. D. Vivek Sagar, B. Gereben, I. Callebaut, J. Mornon +9 more
2007Molecular and Cellular Biology102 citations Open access
Semantic Scholar
The E3 Ubiquitin Ligase TEB4 Mediates Degradation of Type 2 Iodothyronine Deiodinase
A. Zavacki, R. A. Drigo, Beatriz C. G. Freitas, M. Chung +6 more
2009Molecular and Cellular Biology91 citations Open access
Semantic Scholar
Accelerated Postnatal Growth Increases Lipogenic Gene Expression and Adipocyte Size in Low–Birth Weight Mice
E. Isganaitis, J. Jiménez-Chillarón, M. Woo, A. Chow +8 more
2009Diabetes89 citations Open access
Semantic Scholar
Activation of the orphan receptor RIP14 by retinoids.
A. Zavacki, J. Lehmann, W. Seol, T. Willson +2 more
1997Proceedings of the National Academy of Sciences of the United States of America89 citations Open access
Semantic Scholar
Physiological role and regulation of iodothyronine deiodinases: a 2011 update
A. Marsili, A. Zavacki, J. Harney, P. Larsen
2011Journal of Endocrinological Investigation85 citations Open access
Semantic Scholar
Repair-Related Activation of Hedgehog Signaling in Stromal Cells Promotes Intrahepatic Hypothyroidism
B. Bohinc, G. Michelotti, G. Xie, H. Pang +10 more
2014Endocrinology77 citations Open access
Semantic Scholar
Coupled tRNA(Sec)-dependent assembly of the selenocysteine decoding apparatus.
A. Zavacki, J. Mansell, M. Chung, Boris Klimovitsky +2 more
2003Molecules and Cells77 citations Open access
Semantic Scholar
In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases.
Cyntia Curcio-Morelli, B. Gereben, A. Zavacki, Brian W. Kim +4 more
2003Endocrinology75 citations Open access
Semantic Scholar
Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific.
A. Zavacki, J. Harney, G. A. Brent, P. Larsen
1993Molecular Endocrinology66 citations
Semantic Scholar
Type 2 iodothyronine deiodinase levels are higher in slow-twitch than fast-twitch mouse skeletal muscle and are increased in hypothyroidism.
A. Marsili, W. Ramadan, J. Harney, M. Mulcahey +10 more
2010Endocrinology63 citations Open access
Semantic Scholar
The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress
S. Sagliocchi, A. Cicatiello, E. Di Cicco, R. Ambrosio +12 more
2019Redox Biology58 citations Open access
Semantic Scholar
Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2.
Brian W. Kim, A. Zavacki, Cyntia Curcio-Morelli, M. Dentice +3 more
2003Molecular Endocrinology57 citations Open access
Semantic Scholar
Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations.
M. Christoffolete, R. A. Drigo, F. Gazoni, S. M. Tente +5 more
2007Endocrinology55 citations
Semantic Scholar
Differential Growth Rates of Benign vs. Malignant Thyroid Nodules
T. Angell, Chirag M. Vyas, M. Medici, Zhi-Hong Wang +17 more
2017Journal of Clinical Endocrinology and Metabolism52 citations Open access
Semantic Scholar
Antioxidant function of a novel selenoprotein in Drosophila melanogaster
N. Morozova, Erin P. Forry, Elena Shahid, A. Zavacki +3 more
2003Genes to Cells52 citations Open access
Semantic Scholar
A Novel Pathway Regulates Thyroid Hormone Availability in Rat and Human Hypothalamic Neurosecretory Neurons
I. Kalló, P. Mohácsik, B. Vida, Anikó Zeöld +16 more
2012PLoS ONE51 citations Open access
Semantic Scholar
Maternal Thimerosal Exposure Results in Aberrant Cerebellar Oxidative Stress, Thyroid Hormone Metabolism, and Motor Behavior in Rat Pups; Sex- and Strain-Dependent Effects
Z. L. Sulkowski, T. Chen, S. Midha, A. Zavacki +1 more
2011Cerebellum48 citations
Semantic Scholar
Quantitative Analysis of the Benefits and Risk of Thyroid Nodule Evaluation in Patients ≥70 Years Old
Zhi-Hong Wang, Chirag M. Vyas, Olivia Van Benschoten, Matt A. Nehs +17 more
2018Thyroid43 citations
Semantic Scholar
The selective loss of the type 2 iodothyronine deiodinase in mouse thyrotrophs increases basal TSH but blunts the thyrotropin response to hypothyroidism.
C. Luongo, Cecilia Martin, K. R. Vella, A. Marsili +6 more
2015Endocrinology43 citations Open access
Semantic Scholar
Type II iodothyronine deiodinase provides intracellular 3,5,3'-triiodothyronine to normal and regenerating mouse skeletal muscle.
A. Marsili, D. Tang, J. Harney, Prabhat Singh +4 more
2011American Journal of Physiology. Endocrinology and Metabolism41 citations Open access
Semantic Scholar
Retinoid-X receptor (RXR) differentially augments thyroid hormone response in cell lines as a function of the response element and endogenous RXR content.
J.-H. Hsu, A. Zavacki, J. Harney, G. Brent
1995Endocrinology41 citations
Semantic Scholar
Soy protein diet alters expression of hepatic genes regulating fatty acid and thyroid hormone metabolism in the male rat.
F. Simmen, C. P. Mercado, A. Zavacki, Stephen A. Huang +4 more
2010Journal of Nutritional Biochemistry36 citations
Semantic Scholar
FOR, a Novel Orphan Nuclear Receptor Related to Farnesoid X Receptor*
Y. Seo, S. Sanyal, Han-Jong Kim, D. Won +9 more
2002Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Calcium channel agonists and antagonists: effects of chronic treatment on pituitary prolactin synthesis and intracellular calcium.
P. M. Hinkle, A. E. Jackson, Thomas M. Thompson, A. Zavacki +2 more
1988Molecular Endocrinology35 citations Open access
Semantic Scholar
Disrupted brain thyroid hormone homeostasis and altered thyroid hormone-dependent brain gene expression in autism spectrum disorders.
A. Khan, J. Harney, A. Zavacki, E. Sajdel-Sulkowska
2014Journal of Physiology and Pharmacology34 citations
Semantic Scholar
Type-2 iodothyronine 5'deiodinase (D2) in skeletal muscle of C57Bl/6 mice. II. Evidence for a role of D2 in the hypermetabolism of thyroid hormone receptor alpha-deficient mice.
W. Ramadan, A. Marsili, P. Larsen, A. Zavacki +1 more
2011Endocrinology34 citations Open access
Semantic Scholar
Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway
M. Christoffolete, M. Doleschall, P. Egri, Zsolt Liposits +3 more
2010Journal of Endocrinology33 citations Open access
Semantic Scholar
Thyroid-Stimulating Hormone and Thyroid-Stimulating Hormone Receptor Structure-Function Relationships
A. Zavacki, M. Christoffolete, S. M. Tente, V. Goncalves +8 more
200233 citations
Semantic Scholar
Thyroxine-induced induction of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase
A. Marsili, E. Sánchez, P. Singru, J. Harney +3 more
2011Journal of Endocrinology29 citations Open access
Semantic Scholar
Thyroid Hormone Enhances Angiogenesis and the Warburg Effect in Squamous Cell Carcinomas
C. Miro, A. Nappi, A. Cicatiello, E. Di Cicco +11 more
2021Cancers26 citations Open access
Semantic Scholar
Differential effects of refeeding on melanocortin-responsive neurons in the hypothalamic paraventricular nucleus.
E. Sánchez, P. Singru, Runa Acharya, M. Bodria +4 more
2008Endocrinology26 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

J. Harney×19
Invite
J. Harney — researcher profile on SciRah
A. Bianco×12
Invite
A. Bianco — researcher profile on SciRah
M. Dentice×11
Invite
M. Dentice — researcher profile on SciRah
P. Larsen×10
Invite
P. Larsen — researcher profile on SciRah

×10

Invite

A. Marsili — researcher profile on SciRah

Invite

B. Gereben — researcher profile on SciRah

D. Salvatore×8

Invite

D. Salvatore — researcher profile on SciRah

P. R. Larsen×8

Invite

P. R. Larsen — researcher profile on SciRah

Stephen A. Huang×5

Invite

Stephen A. Huang — researcher profile on SciRah

Anikó Zeöld×5

Invite

Anikó Zeöld — researcher profile on SciRah

M. Christoffolete×5

Invite

M. Christoffolete — researcher profile on SciRah

Brian W. Kim×4

Invite

Brian W. Kim — researcher profile on SciRah