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B. Gereben · SciRah

Researcher profile · Semantic Scholar

B. Gereben

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B. Gereben — researcher profile on SciRah

h-index: 45
Works: 112
Citations: 7,764

Most-cited papers

Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling.
B. Gereben, A. Zavacki, S. Ribich, Brian W. Kim +4 more
2008Endocrine reviews845 citations Open access
Semantic Scholar
Paradigms of Dynamic Control of Thyroid Hormone Signaling.
A. Bianco, A. Dumitrescu, B. Gereben, M. O. Ribeiro +3 more
2019Endocrine reviews256 citations Open access
Semantic Scholar
The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate
M. Dentice, Amitabha Bandyopadhyay, B. Gereben, I. Callebaut +12 more
2005Nature Cell Biology225 citations Open access
Semantic Scholar
Activation and inactivation of thyroid hormone by deiodinases: Local action with general consequences
B. Gereben, Anikó Zeöld, M. Dentice, D. Salvatore +1 more
2008Cellular and Molecular Life Sciences219 citations Open access
Semantic Scholar
American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models
A. Bianco, G. Anderson, D. Forrest, V. Galton +11 more
2014Thyroid206 citations Open access
Semantic Scholar
Lipopolysaccharide induces type 2 iodothyronine deiodinase in the mediobasal hypothalamus: implications for the nonthyroidal illness syndrome.
C. Fekete, B. Gereben, M. Doleschall, J. Harney +9 more
2004Endocrinology184 citations Open access
Semantic Scholar
Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.
Beatriz C. G. Freitas, B. Gereben, Melany Castillo, I. Kalló +10 more
2010Journal of Clinical Investigation167 citations Open access
Semantic Scholar
Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine.
J. P. S. Werneck de Castro, Tatiana L Fonseca, C. Ueta, Elizabeth A Mcaninch +5 more
2015Journal of Clinical Investigation165 citations Open access
Semantic Scholar
Coordination of hypothalamic and pituitary T3 production regulates TSH expression.
Tatiana L Fonseca, Mayrin Correa-Medina, M. Campos, G. Wittmann +9 more
2013Journal of Clinical Investigation146 citations Open access
Semantic Scholar
The Iodothyronine Selenodeiodinases Are Thioredoxin-fold Family Proteins Containing a Glycoside Hydrolase Clan GH-A-like Structure*
I. Callebaut, Cyntia Curcio-Morelli, J. Mornon, B. Gereben +7 more
2003Journal of Biological Chemistry136 citations Open access
Semantic Scholar
Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation.
Cyntia Curcio-Morelli, A. Zavacki, Marcelo Christofollete, B. Gereben +5 more
2003Journal of Clinical Investigation132 citations Open access
Semantic Scholar
Scope and limitations of iodothyronine deiodinases in hypothyroidism
B. Gereben, Elizabeth A Mcaninch, M. O. Ribeiro, A. Bianco
2015Nature Reviews Endocrinology130 citations Open access
Semantic Scholar
Human Type 3 Iodothyronine Selenodeiodinase Is Located in the Plasma Membrane and Undergoes Rapid Internalization to Endosomes*
M. Baqui, Diego Botero, B. Gereben, C. Curcio +5 more
2003Journal of Biological Chemistry130 citations Open access
Semantic Scholar
Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function
A. Yavari, C. Stocker, S. Ghaffari, E. Wargent +50 more
2016Cell Metabolism106 citations Open access
Semantic Scholar
Ubiquitination-Induced Conformational Change within the Deiodinase Dimer Is a Switch Regulating Enzyme Activity
G. D. Vivek Sagar, B. Gereben, I. Callebaut, J. Mornon +9 more
2007Molecular and Cellular Biology102 citations Open access
Semantic Scholar
The E3 Ubiquitin Ligase TEB4 Mediates Degradation of Type 2 Iodothyronine Deiodinase
A. Zavacki, R. A. Drigo, Beatriz C. G. Freitas, M. Chung +6 more
2009Molecular and Cellular Biology91 citations Open access
Semantic Scholar
Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain
Sungro Jo, Tatiana L Fonseca, Barbara M.L.C. Bocco, G. W. Fernandes +18 more
2018Journal of Clinical Investigation89 citations Open access
Semantic Scholar
Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes.
Elizabeth A Mcaninch, Sungro Jo, Nailliw Z. Preite, E. Farkas +11 more
2015Journal of Clinical Endocrinology and Metabolism89 citations Open access
Semantic Scholar
Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism
Steffy W. M. Jansen, A. Akintola, F. Roelfsema, E. van der Spoel +12 more
2015Scientific Reports86 citations Open access
Semantic Scholar
In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases.
Cyntia Curcio-Morelli, B. Gereben, A. Zavacki, Brian W. Kim +4 more
2003Endocrinology75 citations Open access
Semantic Scholar
KISS1R intracellular trafficking and degradation: effect of the Arg386Pro disease-associated mutation.
Suzy D. C. Bianco, Lauren E. Vandepas, Mayrin Correa-Medina, B. Gereben +6 more
2011Endocrinology74 citations Open access
Semantic Scholar
Characterization of the Nuclear Factor-κB Responsiveness of the Human dio2 Gene
Anikó Zeöld, M. Doleschall, Michael C. Haffner, L. P. Capelo +7 more
200670 citations Open access
Semantic Scholar
Distribution and ultrastructural localization of the glucagon-like peptide-1 receptor (GLP-1R) in the rat brain
E. Farkas, A. Szilvásy-Szabó, Yvette Ruska, Richárd Sinkó +6 more
2020Brain Structure and Function69 citations Open access
Semantic Scholar
Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain
S. Remaud, Fernando C. Ortiz, Marine Perret-Jeanneret, M. Aigrot +9 more
2017eLife65 citations Open access
Semantic Scholar
Thyroid Hormone and the Neuroglia: Both Source and Target
P. Mohácsik, Anikó Zeöld, A. Bianco, B. Gereben
2011Journal of Thyroid Research61 citations Open access
Semantic Scholar
Neuronal Hypoxia Induces Hsp40-Mediated Nuclear Import of Type 3 Deiodinase As an Adaptive Mechanism to Reduce Cellular Metabolism
Sungro Jo, I. Kalló, Zsuzsanna Bardóczi, R. Arrojo e Drigo +7 more
2012Journal of Neuroscience59 citations Open access
Semantic Scholar
Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice.
Barbara M.L.C. Bocco, J. P. Werneck-de-Castro, K. C. Oliveira, G. W. Fernandes +10 more
2016Endocrinology58 citations Open access
Semantic Scholar
Tissue-Specific Inactivation of Type 2 Deiodinase Reveals Multilevel Control of Fatty Acid Oxidation by Thyroid Hormone in the Mouse
Tatiana L Fonseca, J. P. Werneck-de-Castro, Melany Castillo, Barbara M.L.C. Bocco +7 more
2014Diabetes58 citations Open access
Semantic Scholar
A Novel Pathway Regulates Thyroid Hormone Availability in Rat and Human Hypothalamic Neurosecretory Neurons
I. Kalló, P. Mohácsik, B. Vida, Anikó Zeöld +16 more
2012PLoS ONE51 citations Open access
Semantic Scholar
Chronic cardiac-specific thyrotoxicosis increases myocardial beta-adrenergic responsiveness.
Suzy D. Carvalho-Bianco, Brian W. Kim, Julie X. Zhang, J. Harney +5 more
2004Molecular Endocrinology51 citations Open access
Semantic Scholar
Thyroid hormone activation by type 2 deiodinase mediates exercise‐induced peroxisome proliferator‐activated receptor‐γ coactivator‐1α expression in skeletal muscle
Barbara M.L.C. Bocco, R. Louzada, D. Silvestre, M. S. Santos +9 more
2016Journal of Physiology50 citations Open access
Semantic Scholar
The thyroid hormone-inactivating deiodinase functions as a homodimer.
G. D. Sagar, B. Gereben, I. Callebaut, J. Mornon +8 more
2008Molecular Endocrinology48 citations Open access
Semantic Scholar
Lasting changes in social behavior and amygdala function following traumatic experience induced by a single series of foot-shocks.
É. Mikics, M. Tóth, P. Varju, B. Gereben +6 more
2008Psychoneuroendocrinology46 citations
Semantic Scholar
Endotoxin-induced inflammation down-regulates l-type amino acid transporter 1 (LAT1) expression at the blood–brain barrier of male rats and mice
G. Wittmann, P. Mohácsik, M. Y. Balkhi, B. Gereben +1 more
2015Fluids and Barriers of the CNS45 citations Open access
Semantic Scholar
Pretranslational Regulation of Type 2 Deiodinase
B. Gereben, D. Salvatore
2005Thyroid45 citations
Semantic Scholar
Triiodothyronine (T3) promotes brown fat hyperplasia via thyroid hormone receptor α mediated adipocyte progenitor cell proliferation
Shengnan Liu, Siyi Shen, Ying Yan, Chao Sun +19 more
2022Nature Communications44 citations Open access
Semantic Scholar
Metabolic Instability of Type 2 Deiodinase Is Transferable To Stable Proteins Independently of Subcellular Localization*
Anikó Zeöld, Lívia Pormüller, M. Dentice, J. Harney +4 more
2006Journal of Biological Chemistry44 citations
Semantic Scholar
Ontogenic redistribution of type 2 deiodinase messenger ribonucleic acid in the brain of chicken.
B. Gereben, J. Pachucki, A. Kollár, Zsolt Liposits +1 more
2004Endocrinology41 citations
Semantic Scholar
Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity
Tatiana L Fonseca, G. W. Fernandes, Elizabeth A Mcaninch, Barbara M.L.C. Bocco +9 more
2015Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain.
C. Fekete, Beatriz C. G. Freitas, Anikó Zeöld, G. Wittmann +7 more
2007Endocrinology35 citations
Semantic Scholar
A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System
E. Farkas, E. Varga, Balázs Kovács, A. Szilvásy-Szabó +22 more
2020iScience34 citations Open access
Semantic Scholar
Interleukin‐6 Receptor α is Co‐localised with Melanin‐Concentrating Hormone in Human and Mouse Hypothalamus
E. Schéle, C. Fekete, P. Egri, T. Füzesi +7 more
2012Journal of neuroendocrinology34 citations Open access
Semantic Scholar
Parallel regulation of thyroid hormone transporters OATP1c1 and MCT8 during and after endotoxemia at the blood-brain barrier of male rodents.
G. Wittmann, Judit Szabon, P. Mohácsik, Shira S Nouriel +3 more
2015Endocrinology33 citations Open access
Semantic Scholar
Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway
M. Christoffolete, M. Doleschall, P. Egri, Zsolt Liposits +3 more
2010Journal of Endocrinology33 citations Open access
Semantic Scholar
Characterization of the nuclear factor-kappa B responsiveness of the human dio2 gene.
Anikó Zeöld, M. Doleschall, Michael C. Haffner, L. P. Capelo +7 more
2006Endocrinology31 citations
Semantic Scholar
Thyroid Hormone Signaling in Male Mouse Skeletal Muscle Is Largely Independent of D2 in Myocytes.
J. P. Werneck-de-Castro, Tatiana L Fonseca, D. Ignácio, G. W. Fernandes +6 more
2015Endocrinology26 citations Open access
Semantic Scholar
Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis.
R. A. Drigo, Tatiana L Fonseca, Melany Castillo, M. Salathe +4 more
2011Molecular Endocrinology26 citations Open access
Semantic Scholar
The type II deiodinase is retrotranslocated to the cytoplasm and proteasomes via p97/Atx3 complex.
R. A. Drigo, P. Egri, Sungro Jo, B. Gereben +1 more
2013Molecular Endocrinology25 citations Open access
Semantic Scholar
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Regulates the Hypothalamo-Pituitary-Thyroid (HPT) Axis via Type 2 Deiodinase in Male Mice.
P. Egri, C. Fekete, Á. Dénes, D. Reglodi +3 more
2016Endocrinology24 citations
Semantic Scholar
American Society for Bone and Mineral Research (ASBMR)
C. Fekete, B. Gereben, M. Doleschall, Harney Jw +8 more
200523 citations Open access
Semantic Scholar

Frequent co-authors

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A. Bianco×30
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A. Bianco — researcher profile on SciRah
C. Fekete×22
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C. Fekete — researcher profile on SciRah
Anikó Zeöld×13
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Anikó Zeöld — researcher profile on SciRah
Zsolt Liposits×12
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Zsolt Liposits — researcher profile on SciRah

×11

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J. Harney — researcher profile on SciRah

Tatiana L Fonseca×10

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Tatiana L Fonseca — researcher profile on SciRah

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A. Zavacki — researcher profile on SciRah

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R. Lechan — researcher profile on SciRah

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P. Egri — researcher profile on SciRah

P. Mohácsik×8

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P. Mohácsik — researcher profile on SciRah

Elizabeth A Mcaninch×7

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Elizabeth A Mcaninch — researcher profile on SciRah

M. O. Ribeiro×6

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M. O. Ribeiro — researcher profile on SciRah