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S. Fettner · SciRah

Researcher profile · Semantic Scholar

S. Fettner

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S. Fettner — researcher profile on SciRah

h-index: 16
Works: 28
Citations: 885

Most-cited papers

The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP™) predicts in vivo metabolic inhibition
A. Rakhit, Michael P. Pantze, S. Fettner, H. Jones +4 more
2007European Journal of Clinical Pharmacology125 citations
Semantic Scholar
Phase I trial of 40-kd branched pegylated interferon alfa-2a for patients with advanced renal cell carcinoma.
R. Motzer, A. Rakhit, M. Ginsberg, K. Rittweger +4 more
2001Journal of Clinical Oncology102 citations
Semantic Scholar
Pharmacokinetic and Pharmacodynamic Analysis of Subcutaneous Tocilizumab in Patients With Rheumatoid Arthritis From 2 Randomized, Controlled Trials: SUMMACTA and BREVACTA
Hisham Y. Abdallah, J. Hsu, P. Lu, S. Fettner +6 more
2016Journal of clinical pharmacology90 citations Open access
Semantic Scholar
Effect of food on the pharmacokinetics of erlotinib, an orally active epidermal growth factor receptor tyrosine-kinase inhibitor, in healthy individuals
J. Ling, S. Fettner, B. Lum, M. Riek +1 more
2008Anti-Cancer Drugs88 citations
Semantic Scholar
731 Interim results of a multiple ascending dose study of R1626, a novel nucleoside analog targeting hcv polymerase in chronic HCV patients
S. Roberts, G. Cooksley, D. Shaw, H. Berns +9 more
200654 citations
Semantic Scholar
Safety and Pharmacokinetic Characterization of Nacubactam, a Novel β-Lactamase Inhibitor, Alone and in Combination with Meropenem, in Healthy Volunteers
Navita L. Mallalieu, E. Winter, S. Fettner, Katie Patel +7 more
2020Antimicrobial Agents and Chemotherapy53 citations Open access
Semantic Scholar
Erlotinib in combination with capecitabine and docetaxel in patients with metastatic breast cancer: a dose-escalation study.
C. Twelves, J. Trigo, Rob J. Jones, F. De Rosa +4 more
2008European Journal of Cancer53 citations
Semantic Scholar
A phase Ib dose-escalation study of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer patients.
E. Van Cutsem, C. Verslype, P. Beale, Stephen J. Clarke +6 more
2008Annals of Oncology42 citations Open access
Semantic Scholar
The effect of rifampicin, a prototypical CYP3A4 inducer, on erlotinib pharmacokinetics in healthy subjects
M. Hamilton, J. Wolf, D. Drolet, S. Fettner +3 more
2014Cancer Chemotherapy and Pharmacology41 citations
Semantic Scholar
Down‐regulation of the pharmacokinetic‐pharmacodynamic response to interleukin‐12 during long‐term administration to patients with renal cell carcinoma and evaluation of the mechanism of this “adaptive response” in mice
A. Rakhit, Mitch Yeon, J. Ferrante, S. Fettner +8 more
1999Clinical pharmacology and therapy41 citations
Semantic Scholar
Phase I Evaluation of a 40-kDa Branched-Chain Long-Acting Pegylated IFN-α-2a With and Without Cytarabine in Patients with Chronic Myelogenous Leukemia
M. Talpaz, A. Rakhit, K. Rittweger, S. O'Brien +4 more
2005Clinical Cancer Research34 citations Open access
Semantic Scholar
Phase 1b Dose Escalation Study of Erlotinib in Combination with Infusional 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Advanced Solid Tumors
A. Hanauske, J. Cassidy, J. Sastre, C. Bolling +6 more
2007Clinical Cancer Research23 citations Open access
Semantic Scholar
Pharmacokinetics and pharmacodynamics of tocilizumab after subcutaneous administration in patients with rheumatoid arthritis.
Xiao-Ping Zhang, Ya-Chi Chen, S. Fettner, L. Rowell +3 more
2013International journal of clinical pharmacology and therapeutics20 citations
Semantic Scholar
A phase 1b dose-escalation trial of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer (MCRC) patients
J. Delord, P. Beale, E. Van Cutsem, S. Clarke +6 more
200420 citations
Semantic Scholar
Characterization of AUCs from Sparsely Sampled Populations in Toxicology Studies
Sudhakar M. Pai, S. Fettner, G. Hajian, M. Cayen +1 more
1996Pharmaceutical Research20 citations
Semantic Scholar
Evidence of bioequivalence and positive patient user handling of a tocilizumab autoinjector
S. Fettner, C. Mela, Florian Wildenhahn, M. Tavanti +3 more
2019Expert Opinion on Drug Delivery16 citations Open access
Semantic Scholar
Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer
H. Calvert, C. Twelves, M. Ranson, R. Plummer +6 more
2014Anti-Cancer Drugs15 citations
Semantic Scholar
Pharmacokinetic Interaction Study of Ritonavir-Boosted Saquinavir in Combination with Rifabutin in Healthy Subjects
Xiao-Ping Zhang, S. Fettner, E. Zwanziger, L. Rowell +1 more
2010Antimicrobial Agents and Chemotherapy9 citations Open access
Semantic Scholar
Design and Characterization of R1626, A Prodrug of the HCV Replication Inhibitor R1479 (4′-Azidocytidine) With Enhanced Oral Bioavailability
K. Klumpp, D. Smith, M. Brandl, T. Alfredson +28 more
20079 citations
Semantic Scholar
Safety, tolerability, pharmacokinetics, and pharmacodynamics of a TLR7 agonist prodrug RO6870868 in healthy volunteers
J. Grippo, I. Folitar, S. Passe, Qiu-Di Jiang +3 more
2021Clinical and Translational Science8 citations Open access
Semantic Scholar
Assessment of disease-drug-drug interaction between single-dose tocilizumab and oral contraceptives in women with active rheumatoid arthritis.
Xiao-Ping Zhang, L. Rowell, S. Fettner, C. Lau +1 more
2014International journal of clinical pharmacology and therapeutics8 citations
Semantic Scholar
A phase 1b dose-escalation trial of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer (MCRC) patients.
J. Delord, P. Beale, E. Van Cutsem, S. Clarke +6 more
2004Journal of Clinical Oncology8 citations
Semantic Scholar
The effect of erlotinib on CYP3A4 activity, as quantified by the erythromycin breath test and oral midazolam kinetics in cancer patients: Preliminary results
H. Calvert, C. Twelves, M. Ranson, A. Anthoney +6 more
20054 citations
Semantic Scholar
Pharmacokinetic-pharmacodynamic (PK-PD) modeling for a new antihypertensive agent (neutral metalloendopeptidase inhibitor SCH 42354) in patients with mild to moderate hypertension
S. Fettner, Sudhakar M. Pai, V. Batra, G.-R. Zhu +2 more
2004European Journal of Clinical Pharmacology3 citations
Semantic Scholar
373 Lack of pharmacokinetic interaction between erlotinib, docetaxel and capecitabine in breast cancer patients
A. Rakhit, S. Fettner, S. Davis, R. Abbas +4 more
20032 citations
Semantic Scholar
A171: Tocilizumab Dosing in Juvenile Idiopathic Arthritis: Optimizing for Different Juvenile Idiopathic Arthritis Type and Patient Body Weight
P. Lu, J. Hsu, C. Keane, S. Fettner +5 more
20140 citations
Semantic Scholar
556 Clinical pharmacokinetics of erlotinib in healthy subjects
R. Abbas, S. Fettner, M. Riek, S. Davis +3 more
20030 citations
Semantic Scholar
Ecarin Time Superior to Aptt in Monitoring Peghirudin Effects
R. Velagapudi, J. Badimón, P. Kyrle, M. Sujatta +5 more
19990 citations
Semantic Scholar

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