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P. Chaplin · SciRah

Researcher profile · Semantic Scholar

P. Chaplin

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P. Chaplin — researcher profile on SciRah

h-index: 39
Works: 93
Citations: 4,434

Most-cited papers

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA
K. Ewer, T. Rampling, N. Venkatraman, Georgina S. Bowyer +52 more
2015New England Journal of Medicine331 citations Open access
Semantic Scholar
Mouse CD8α+ DCs and human BDCA3+ DCs are major producers of IFN-λ in response to poly IC
H. Lauterbach, B. Bathke, S. Gilles, C. Traidl-Hoffmann +12 more
2010Journal of Experimental Medicine246 citations Open access
Semantic Scholar
Phase 3 Efficacy Trial of Modified Vaccinia Ankara as a Vaccine against Smallpox.
P. Pittman, M. Hahn, Heechoon Lee, Craig D Koca +9 more
2019New England Journal of Medicine218 citations Open access
Semantic Scholar
Modified Vaccinia Virus Ankara Protects Macaques against Respiratory Challenge with Monkeypox Virus
K. Stittelaar, G. van Amerongen, I. Kondova, T. Kuiken +8 more
2005Journal of Virology214 citations Open access
Semantic Scholar
Involvement of caveolae in the uptake of respiratory syncytial virus antigen by dendritic cells
D. Werling, Jayne C. Hope, P. Chaplin, Robert A. Collins +2 more
1999Journal of Leukocyte Biology205 citations
Semantic Scholar
Safety and immunogenicity of IMVAMUNE, a promising candidate as a third generation smallpox vaccine.
J. Vollmar, N. Arndtz, K. Eckl, T. Thomsen +10 more
2006Vaccine172 citations
Semantic Scholar
Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection.
C. Samuelsson, J. Hausmann, H. Lauterbach, M. Schmidt +6 more
2008Journal of Clinical Investigation160 citations Open access
Semantic Scholar
Comparison of lyophilized versus liquid modified vaccinia Ankara (MVA) formulations and subcutaneous versus intradermal routes of administration in healthy vaccinia-naïve subjects
S. Frey, A. Wald, S. Edupuganti, L. Jackson +21 more
2015Vaccine143 citations Open access
Semantic Scholar
A randomized, double-blind, dose-finding Phase II study to evaluate immunogenicity and safety of the third generation smallpox vaccine candidate IMVAMUNE®
A. von Krempelhuber, J. Vollmar, R. Pokorny, Petra Rapp +7 more
2009Vaccine128 citations Open access
Semantic Scholar
Safety and Immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic Smallpox Vaccine in Vaccinia-Naive and Experienced Human Immunodeficiency Virus-Infected Individuals: An Open-Label, Controlled Clinical Phase II Trial
E. Overton, J. Stapleton, I. Frank, S. Hassler +15 more
2015Open Forum Infectious Diseases123 citations Open access
Semantic Scholar
Safety, immunogenicity, and surrogate markers of clinical efficacy for modified vaccinia Ankara as a smallpox vaccine in HIV-infected subjects.
R. Greenberg, E. Overton, D. Haas, I. Frank +6 more
2013Journal of Infectious Diseases122 citations Open access
Semantic Scholar
Clinical and immunologic responses to multiple doses of IMVAMUNE (Modified Vaccinia Ankara) followed by Dryvax challenge.
S. Frey, Frances K. Newman, J. Kennedy, Vera Sobek +7 more
2007Vaccine120 citations Open access
Semantic Scholar
Therapeutic Vaccination of HIV-1-Infected Patients on Haart with a Recombinant HIV-1 Nef-Expressing Mva: Safety, Immunogenicity and Influence on Viral Load during Treatment Interruption
E. Harrer, M. Bauerle, B. Ferstl, P. Chaplin +13 more
2005Antiviral Therapy109 citations Open access
Semantic Scholar
Targeting Improves the Efficacy of a DNA Vaccine against Corynebacterium pseudotuberculosis in Sheep
P. Chaplin, R. De Rose, J. S. Boyle, P. McWaters +4 more
1999Infection and Immunity96 citations Open access
Semantic Scholar
Genomic sequence of chorioallantois vaccinia virus Ankara, the ancestor of modified vaccinia virus Ankara.
Christine Meisinger-Henschel, M. Schmidt, Susanne Lukassen, B. Linke +7 more
2007Journal of General Virology95 citations Open access
Semantic Scholar
A Multicenter, Open-Label, Controlled Phase II Study to Evaluate Safety and Immunogenicity of MVA Smallpox Vaccine (IMVAMUNE) in 18–40 Year Old Subjects with Diagnosed Atopic Dermatitis
R. Greenberg, Y. Hurley, Dinh V. Dinh, S. Mraz +11 more
2015PLoS ONE89 citations Open access
Semantic Scholar
Boosting T Cell-Mediated Immunity to Tyrosinase by Vaccinia Virus-Transduced, CD34+-Derived Dendritic Cell Vaccination
M. Di Nicola, C. Carlo-Stella, R. Mortarini, P. Baldassari +10 more
2004Clinical Cancer Research86 citations Open access
Semantic Scholar
A randomized phase II trial to compare safety and immunogenicity of the MVA-BN smallpox vaccine at various doses in adults with a history of AIDS.
E. Overton, S. Lawrence, J. Stapleton, H. Weidenthaler +5 more
2020Vaccine80 citations
Semantic Scholar
Modified vaccinia Ankara strains with identical coding sequences actually represent complex mixtures of viruses that determine the biological properties of each strain.
M. Suter, Christine Meisinger-Henschel, M. Tzatzaris, Vanessa Hülsemann +5 more
2009Vaccine73 citations
Semantic Scholar
Fasciola hepatica cathepsin L suppresses sheep lymphocyte proliferation in vitro and modulates surface CD4 expression on human and ovine T cells
Rhoda Prowse, P. Chaplin, H. Robinson, T. Spithill
2002Parasite immunology (Print)70 citations
Semantic Scholar
A Randomized, Double-Blind, Placebo-Controlled Phase II Trial Investigating the Safety and Immunogenicity of Modified Vaccinia Ankara Smallpox Vaccine (MVA-BN®) in 56-80-Year-Old Subjects
R. Greenberg, C. Hay, J. Stapleton, T. Marbury +12 more
2016PLoS ONE66 citations Open access
Semantic Scholar
Safety and Immunogenicity of IMVAMUNE® Smallpox Vaccine Using Different Strategies for a Post Event Scenario
S. Frey, P. Winokur, R. Salata, S. El-Kamary +9 more
2013Vaccine66 citations Open access
Semantic Scholar
A phase I vaccination study with tyrosinase in patients with stage II melanoma using recombinant modified vaccinia virus Ankara (MVA-hTyr)
R. Meyer, C. Britten, U. Siepmann, Barbara Petzold +20 more
2005Cancer Immunology and Immunotherapy64 citations Open access
Semantic Scholar
Efficacy of DNA vaccination by different routes of immunisation in sheep.
R. De Rose, J. Tennent, P. McWaters, P. Chaplin +4 more
2002Veterinary Immunology and Immunopathology62 citations
Semantic Scholar
Prime Boost Vaccination Strategies: CD8 T Cell Numbers, Protection, and Th1 Bias1
T. Woodberry, J. Gardner, S. Elliott, S. Leyrer +3 more
2003Journal of Immunology60 citations Open access
Semantic Scholar
The Vaccinia Virus O1 Protein Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase 1/2 and Promotes Viral Virulence
Marc Schweneker, Susanne Lukassen, Michaela Späth, M. Wolferstätter +6 more
2011Journal of Virology57 citations Open access
Semantic Scholar
Coexpression of Interleukin-12 Chains by a Self-Splicing Vector Increases the Protective Cellular Immune Response of DNA and Mycobacterium bovis BCG Vaccines against Mycobacterium tuberculosis
U. Palendira, A. Kamath, Carl G. Feng, E. Martin +3 more
2002Infection and Immunity57 citations Open access
Semantic Scholar
Introduction of the Six Major Genomic Deletions of Modified Vaccinia Virus Ankara (MVA) into the Parental Vaccinia Virus Is Not Sufficient To Reproduce an MVA-Like Phenotype in Cell Culture and in Mice
Christine Meisinger-Henschel, Michaela Späth, Susanne Lukassen, M. Wolferstätter +7 more
2010Journal of Virology55 citations Open access
Semantic Scholar
Safety and immunogenicity of novel modified vaccinia Ankara-vectored RSV vaccine: A randomized phase I clinical trial.
N. Samy, Daniela Reichhardt, D. Schmidt, Liddy Chen +9 more
2020Vaccine53 citations
Semantic Scholar
Safety and immunogenicity of modified vaccinia Ankara as a smallpox vaccine in people with atopic dermatitis.
F. von Sonnenburg, P. Perona, U. Darsow, J. Ring +6 more
2014Vaccine53 citations
Semantic Scholar
Immediate-Early Expression of a Recombinant Antigen by Modified Vaccinia Virus Ankara Breaks the Immunodominance of Strong Vector-Specific B8R Antigen in Acute and Memory CD8 T-Cell Responses
K. Baur, K. Brinkmann, Marc Schweneker, Juliane Pätzold +6 more
2010Journal of Virology52 citations Open access
Semantic Scholar
Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III trial
E. Overton, S. Lawrence, E. Wagner, Katrin Nopora +9 more
2018PLoS ONE51 citations Open access
Semantic Scholar
Local immune responses to influenza antigen are synergistically enhanced by the adjuvant ISCOMATRIX.
R. Windon, P. Chaplin, P. McWaters, M. Tavarnesi +10 more
2001Vaccine51 citations
Semantic Scholar
The comparative efficacy of CTLA-4 and L-selectin targeted DNA vaccines in mice and sheep.
D. Drew, J. S. Boyle, A. M. Lew, M. Lightowlers +2 more
2001Vaccine50 citations
Semantic Scholar
Broad Antibody and Cellular Immune Response from a Phase 2 Clinical Trial with a Novel Multivalent Poxvirus Based RSV Vaccine.
E. Jordan, S. Lawrence, T. Meyer, D. Schmidt +11 more
2020Journal of Infectious Diseases48 citations
Semantic Scholar
Induction of lymphocyte recruitment in the absence of a detectable immune response.
R. Windon, P. Chaplin, L. Beezum, Alan Coulter +7 more
2000Vaccine47 citations
Semantic Scholar
Phase II Randomized, Double-Blinded Comparison of A Single High Dose (5×108 TCID50) of Modified Vaccinia Ankara Compared To A Standard Dose (1×108 TCID50) in Healthy Vaccinia-Naïve Individuals
S. Frey, P. Winokur, H. Hill, J. Goll +2 more
2014Vaccine45 citations Open access
Semantic Scholar
One- and Two-Dose Vaccinations With Modified Vaccinia Ankara-Bavarian Nordic Induce Durable B-Cell Memory Responses Comparable to Replicating Smallpox Vaccines
Heiko Ilchmann, N. Samy, Daniela Reichhardt, D. Schmidt +8 more
2022Journal of Infectious Diseases43 citations Open access
Semantic Scholar
Optimization and immune recognition of multiple novel conserved HLA-A2, human immunodeficiency virus type 1-specific CTL epitopes.
S. Corbet, H. V. Nielsen, L. Vinner, S. Lauemøller +8 more
2003Journal of General Virology40 citations Open access
Semantic Scholar
Cardiac Safety of Modified Vaccinia Ankara for Vaccination against Smallpox in a Young, Healthy Study Population
E. Zitzmann-Roth, F. von Sonnenburg, S. de la Motte, Nathaly Arndtz-Wiedemann +5 more
2015PLoS ONE39 citations Open access
Semantic Scholar
Evaluation of the efficacy of modified vaccinia Ankara (MVA)/IMVAMUNE® against aerosolized rabbitpox virus in a rabbit model
N. Garza, J. Hatkin, Virginia Livingston, D. Nichols +4 more
2009Vaccine39 citations Open access
Semantic Scholar
Synergistic cancer immunotherapy combines MVA-CD40L induced innate and adaptive immunity with tumor targeting antibodies
J. Medina-Echeverz, M. Hinterberger, M. Testori, M. Geiger +10 more
2019Nature Communications38 citations Open access
Semantic Scholar
A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques
A. Volkmann, G. Koopman, P. Mooij, E. Verschoor +10 more
2022Frontiers in Immunology32 citations Open access
Semantic Scholar
A Novel Naturally Occurring Tandem Promoter in Modified Vaccinia Virus Ankara Drives Very Early Gene Expression and Potent Immune Responses
S. Wennier, K. Brinkmann, Charlotte Steinhäußer, Nicole Mayländer +6 more
2013PLoS ONE31 citations Open access
Semantic Scholar
Enhanced Priming of Multispecific, Murine CD8+ T Cell Responses by DNA Vaccines Expressing Stress Protein-Binding Polytope Peptides1
R. Schirmbeck, N. Fissolo, P. Chaplin, J. Reimann
2003Journal of Immunology29 citations Open access
Semantic Scholar
Dendritic Cells from Mice Neonatally Vaccinated with Modified Vaccinia Virus Ankara Transfer Resistance against Herpes Simplex Virus Type I to Naive One-Week-Old Mice1
M. Franchini, H. Hefti, S. Vollstedt, B. Glanzmann +5 more
2004Journal of Immunology26 citations
Semantic Scholar
Genetic stability of recombinant MVA-BN.
Alexander Timm, C. Enzinger, E. Felder, P. Chaplin
2006Vaccine25 citations
Semantic Scholar
Ovine Interleukin-12: Analysis of Biologic Function and Species Comparison
R. De Rose, Jean-Pierre Y. Scheerlinck, G. Casey, P. Wood +2 more
2000Journal of Interferon and Cytokine Research25 citations
Semantic Scholar
Immunization of Patients with Malignant Melanoma with Autologous CD34+ Cell-Derived Dendritic Cells Transduced Ex Vivo with a Recombinant Replication-Deficient Vaccinia Vector Encoding the Human Tyrosinase Gene: A Phase I Trial
M. Di Nicola, C. Carlo-Stella, A. Anichini, R. Mortarini +13 more
200324 citations
Semantic Scholar
A Recombinant MVA-Based RSV Vaccine Induces T-Cell and Antibody Responses That Cooperate in the Protection Against RSV Infection
K. Endt, Yvonne Wollmann, Jana Haug, Constanze Bernig +7 more
2022Frontiers in Immunology23 citations Open access
Semantic Scholar

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