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N. Fissolo · SciRah

Researcher profile · Semantic Scholar

N. Fissolo

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N. Fissolo — researcher profile on SciRah

h-index: 23
Works: 71
Citations: 1,322

Most-cited papers

NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients.
S. Malhotra, C. Costa, H. Eixarch, C. Keller +26 more
2020Brain : a journal of neurology124 citations Open access
Semantic Scholar
Dual inhibition of proteasomal and lysosomal proteolysis ameliorates autoimmune central nervous system inflammation
N. Fissolo, Marianne Kraus, Michael R. Reich, Miriam Ayturan +3 more
2008European Journal of Immunology76 citations
Semantic Scholar
Naturally Presented Peptides on Major Histocompatibility Complex I and II Molecules Eluted from Central Nervous System of Multiple Sclerosis Patients*
N. Fissolo, Sabrina Haag, K. D. de Graaf, O. Drews +3 more
2009Molecular & Cellular Proteomics75 citations Open access
Semantic Scholar
Search for Specific Biomarkers of IFNβ Bioactivity in Patients with Multiple Sclerosis
S. Malhotra, M. F. Bustamante, F. Pérez-Miralles, J. Río +8 more
2011PLoS ONE53 citations Open access
Semantic Scholar
AID expression identifies interfollicular large B cells as putative precursors of mature B-cell malignancies.
G. Moldenhauer, Sergey W. Popov, Beate Wotschke, S. Brüderlein +6 more
2006Blood47 citations Open access
Semantic Scholar
Treatment with MOG-DNA vaccines induces CD4+CD25+FoxP3+ regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitis
N. Fissolo, C. Costa, R. Nurtdinov, M. F. Bustamante +5 more
2012Journal of Neuroinflammation44 citations Open access
Semantic Scholar
Different immunogenicity of H‐2 Kb‐restricted epitopes in natural variants of the hepatitis B surface antigen
R. Schirmbeck, W. Böhm, N. Fissolo, K. Melber +1 more
2003European Journal of Immunology44 citations
Semantic Scholar
Clinical practice of analysis of anti-drug antibodies against interferon beta and natalizumab in multiple sclerosis patients in Europe: A descriptive study of test results
J. Link, R. Ramanujam, Michael Auer, M. Ryner +27 more
2017PLoS ONE41 citations Open access
Semantic Scholar
Implication of the toll‐like receptor 4 pathway in the response to interferon‐β in multiple sclerosis
M. F. Bustamante, N. Fissolo, J. Río, C. Espejo +7 more
2011Annals of Neurology40 citations
Semantic Scholar
Translation from Cryptic Reading Frames of DNA Vaccines Generates an Extended Repertoire of Immunogenic, MHC Class I-Restricted Epitopes1
R. Schirmbeck, P. Riedl, N. Fissolo, F. Lemonnier +2 more
2005Journal of Immunology38 citations
Semantic Scholar
Priming polyvalent immunity by DNA vaccines expressing chimeric antigens with a stress protein‐capturing, viral J‐domain
R. Schirmbeck, M. Kwissa, N. Fissolo, Shereen F. Elkholy +2 more
2002The FASEB Journal38 citations
Semantic Scholar
DNA-based vaccines for multiple sclerosis: current status and future directions.
N. Fissolo, X. Montalban, M. Comabella
2012Clinical Immunology36 citations
Semantic Scholar
CSF SERPINA3 Levels Are Elevated in Patients With Progressive MS
N. Fissolo, Clara Matute-Blanch, Mohamoud Osman, C. Costa +12 more
2021Neurology: Neuroimmunology & Neuroinflammation35 citations Open access
Semantic Scholar
MRI phenotypes with high neurodegeneration are associated with peripheral blood B-cell changes.
M. Comabella, E. Cantó, R. Nurtdinov, J. Río +8 more
2016Human Molecular Genetics34 citations Open access
Semantic Scholar
CSF chitinase 3-like 1 is associated with iron rims in patients with a first demyelinating event
M. Comabella, M. Clarke, S. Schaedelin, M. Tintoré +10 more
2021Multiple Sclerosis33 citations Open access
Semantic Scholar
Role of high mobility group box protein 1 (HMGB1) in peripheral blood from patients with multiple sclerosis
S. Malhotra, N. Fissolo, M. Tintoré, A. Wing +4 more
2015Journal of Neuroinflammation32 citations Open access
Semantic Scholar
Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course
Elia Gil-Varea, E. Urcelay, C. Vilariño-Güell, C. Costa +21 more
2018Journal of Neuroinflammation30 citations Open access
Semantic Scholar
Enhanced Priming of Multispecific, Murine CD8+ T Cell Responses by DNA Vaccines Expressing Stress Protein-Binding Polytope Peptides1
R. Schirmbeck, N. Fissolo, P. Chaplin, J. Reimann
2003Journal of Immunology29 citations Open access
Semantic Scholar
Serum biomarker levels predict disability progression in patients with primary progressive multiple sclerosis
N. Fissolo, P. Benkert, J. Sastre-Garriga, N. Mongay-Ochoa +32 more
2023Journal of Neurology Neurosurgery & Psychiatry27 citations Open access
Semantic Scholar
Advanced Intercross Line Mapping Suggests That Ncf1 (Ean6) Regulates Severity in an Animal Model of Guillain-Barré Syndrome1
A. Huberle, A. D. Beyeen, Johan Ockinger, Miriam Ayturan +9 more
2009Journal of Immunology27 citations
Semantic Scholar
CSF Chitinase 3–Like 2 Is Associated With Long-term Disability Progression in Patients With Progressive Multiple Sclerosis
M. Comabella, J. Sastre-Garriga, E. Borràs, L. Villar +12 more
2021Neurology: Neuroimmunology & Neuroinflammation26 citations Open access
Semantic Scholar
Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome.
N. Fissolo, S. Schaedelin, L. Villar, J. Lünemann +54 more
2025JAMA Neurology25 citations Open access
Semantic Scholar
Serum neurofilament light chain levels predict long-term disability progression in patients with progressive multiple sclerosis
M. Comabella, J. Sastre-Garriga, Pere Carbonell-Mirabent, N. Fissolo +8 more
2022Journal of Neurology Neurosurgery & Psychiatry24 citations Open access
Semantic Scholar
Immunomodulatory Effects Associated with Cladribine Treatment
N. Fissolo, Laura Calvo-Barreiro, H. Eixarch, U. Boschert +3 more
2021Cells22 citations Open access
Semantic Scholar
DNA vaccines prime CD8+ T cell responses to epitopes of viral antigens produced from overlapping reading frames of a single coding sequence
N. Fissolo, P. Riedl, J. Reimann, R. Schirmbeck
2005European Journal of Immunology22 citations Open access
Semantic Scholar
Development and multi-center validation of a fully automated digital immunoassay for neurofilament light chain: toward a clinical blood test for neuronal injury
David H. Wilson, D. Chan, Lei Chang, Robert Mathis +36 more
2023Clinical Chemistry and Laboratory Medicine21 citations Open access
Semantic Scholar
Serum Neurofilament Levels and PML Risk in Patients With Multiple Sclerosis Treated With Natalizumab
N. Fissolo, B. Pignolet, J. Río, P. Vermersch +16 more
2021Neurology: Neuroimmunology & Neuroinflammation21 citations Open access
Semantic Scholar
Monocyte NOTCH2 expression predicts IFN-β immunogenicity in multiple sclerosis patients.
M. Adriani, Petra Nytrova, Cyprien Mbogning, Signe Hässler +18 more
2018JCI Insight21 citations Open access
Semantic Scholar
Serum Levels of CXCL13 Are Associated With Teriflunomide Response in Patients With Multiple Sclerosis
N. Fissolo, Agustín Pappolla, J. Río, L. Villar +5 more
2022Neurology: Neuroimmunology & Neuroinflammation20 citations Open access
Semantic Scholar
Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II alleles
B. de la Hera, E. Urcelay, D. Brassat, A. Chan +17 more
2014Neurology20 citations Open access
Semantic Scholar
Matrix metalloproteinase 9 is decreased in natalizumab‐treated multiple sclerosis patients at risk for progressive multifocal leukoencephalopathy
N. Fissolo, B. Pignolet, Clara Matute-Blanch, J. Triviño +19 more
2017Annals of Neurology18 citations
Semantic Scholar
Circulating EZH2-positive T cells are decreased in multiple sclerosis patients
S. Malhotra, L. Villar, C. Costa, L. Midaglia +9 more
2018Journal of Neuroinflammation16 citations Open access
Semantic Scholar
Assessment of neuronal and glial serum biomarkers in myelin oligodendrocyte glycoprotein antibody-associated disease: the MULTIMOGAD study
R. Marignier, J. Villacieros-Álvarez, Carmen Espejo, G. Arrambide +40 more
2025Journal of Neurology Neurosurgery & Psychiatry15 citations
Semantic Scholar
Increased cytomegalovirus immune responses at disease onset are protective in the long-term prognosis of patients with multiple sclerosis
M. Comabella, M. Tintoré, Augusto Sao-Avilés, Pere Carbonell-Mirabent +5 more
2022Journal of Neurology Neurosurgery & Psychiatry15 citations
Semantic Scholar
Detection and kinetics of persistent neutralizing anti-interferon-beta antibodies in patients with multiple sclerosis. Results from the ABIRISK prospective cohort study.
P. E. Jensen, C. Warnke, Kathleen Ingenhoven, L. Piccoli +39 more
2019Journal of Neuroimmunology13 citations
Semantic Scholar
Contribution of Blood Biomarkers to Multiple Sclerosis Diagnosis
M. Comabella, Agustín Pappolla, E. Monreal, N. Fissolo +31 more
2025Neurology(R) neuroimmunology & neuroinflammation12 citations Open access
Semantic Scholar
Usefulness of serum neurofilament light chain in chronic inflammatory demyelinating polyradiculoneuropathy.
A. Llauradó, C. García-Carmona, J. Restrepo-Vera, J. Alemañ +11 more
2025Journal of Neurological Sciences12 citations Open access
Semantic Scholar
Molecular dynamics and intracellular signaling of the TNF-R1 with the R92Q mutation.
L. Agulló, S. Malhotra, N. Fissolo, X. Montalban +1 more
2015Journal of Neuroimmunology12 citations
Semantic Scholar
Cytomegalovirus immune responses are associated with lower serum NfL and disability accumulation risk at multiple sclerosis onset
Jan D. Luenemann, Augusto Sao-Avilés, M. Tintoré, L. Midaglia +5 more
2024Multiple Sclerosis11 citations
Semantic Scholar
Increased EBNA1-specific antibody response in primary-progressive multiple sclerosis
M. Comabella, H. Hegen, L. Villar, K. Rejdak +28 more
2024Journal of Neurology10 citations Open access
Semantic Scholar
Cerebrospinal fluid mitochondrial DNA levels in patients with multiple sclerosis
N. Fissolo, Laura Cervera-Carles, Luisa María Villar Guimerans, A. Lleó +10 more
2018Multiple Sclerosis10 citations Open access
Semantic Scholar
Association of Complement Factors With Disability Progression in Primary Progressive Multiple Sclerosis
Jan D Lunemann, H. Hegen, L. M. Villar, Konrad Rejdak +27 more
2024Neurology(R) neuroimmunology & neuroinflammation8 citations Open access
Semantic Scholar
Levels of soluble TNF-RII are increased in serum of patients with primary progressive multiple sclerosis.
N. Fissolo, E. Cantó, Á. Vidal-Jordana, J. Castilló +2 more
2014Journal of Neuroimmunology8 citations
Semantic Scholar
Association of magnetic resonance imaging phenotypes and serum biomarker levels with treatment response and long‐term disease outcomes in multiple sclerosis patients
L. Midaglia, À. Rovira, B. Miró, J. Río +5 more
2023European Journal of Neurology7 citations Open access
Semantic Scholar
Molecular signature associated with cladribine treatment in patients with multiple sclerosis
N. Fissolo, Laura Calvo-Barreiro, H. Eixarch, U. Boschert +9 more
2023Frontiers in Immunology6 citations Open access
Semantic Scholar
The CYP24A1 gene variant rs2762943 is associated with low serum 1,25‐dihydroxyvitamin D levels in multiple sclerosis patients
S. Malhotra, L. Midaglia, Omar Chuquisana, N. Patsopoulos +8 more
2023European Journal of Neurology5 citations Open access
Semantic Scholar
DNA Vaccination Techniques.
N. Fissolo, X. Montalban, M. Comabella
2016Methods in molecular biology4 citations
Semantic Scholar
A stress protein-facilitated antigen expression system for plasmid DNA vaccines.
P. Riedl, N. Fissolo, J. Reimann, R. Schirmbeck
2006Methods in Molecular Medicine4 citations
Semantic Scholar
Severity‐Dependent Neuroaxonal Damage Assessed by Serum Neurofilaments in ICANS Patients Undergoing CD19‐Targeted CAR T‐Cell Therapy
A. Vilaseca, H. Ariño, G. Iacoboni, S. Feijoo +10 more
2025European Journal of Neurology3 citations Open access
Semantic Scholar
Clusterin deficiency is associated with a lack of response to teriflunomide in multiple sclerosis
S. Malhotra, N. Fissolo, C. Rodríguez-Rivera, E. Monreal +15 more
2024Clinical and Translational Medicine3 citations Open access
Semantic Scholar

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M. Comabella×37
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S. Malhotra×11
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