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L. Loram · SciRah

Researcher profile · Semantic Scholar

L. Loram

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L. Loram — researcher profile on SciRah

h-index: 28
Works: 54
Citations: 3,141

Most-cited papers

Morphine activates neuroinflammation in a manner parallel to endotoxin
Xiao-Hui Wang, L. Loram, Khara M. Ramos, A. J. de Jesus +7 more
2012Proceedings of the National Academy of Sciences of the United States of America450 citations Open access
Semantic Scholar
Opioid activation of Toll-Like receptor 4 contributes to drug reinforcement
M. Hutchinson, A. Northcutt, Takato Hiranita, Xiao-Hui Wang +22 more
2012Journal of Neuroscience277 citations Open access
Semantic Scholar
Toll-Like Receptors in Chronic Pain
L. Nicotra, L. Loram, L. Watkins, M. Hutchinson
2011Experimental Neurology257 citations Open access
Semantic Scholar
Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in rats
L. Loram, P. Sholar, F. Taylor, Julie L. Wiesler +6 more
2012Psychoneuroendocrinology190 citations Open access
Semantic Scholar
Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1β
Susannah S. Lewis, M. Hutchinson, N. Rezvani, L. Loram +4 more
2010Neuroscience188 citations Open access
Semantic Scholar
Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia
M. Hutchinson, A. Northcutt, Li Chao, J. Kearney +8 more
2008Brain, behavior, and immunity188 citations Open access
Semantic Scholar
Enduring Reversal Of Neuropathic Pain By A Single Intrathecal Injection Of Adenosine 2A Receptor Agonists: A Novel Therapy For Neuropathic Pain
L. Loram, Jacqueline A. Harrison, E. Sloane, M. Hutchinson +9 more
2009Journal of Neuroscience112 citations Open access
Semantic Scholar
Effects of Ferric Citrate in Patients with Nondialysis-Dependent CKD and Iron Deficiency Anemia.
S. Fishbane, G. Block, L. Loram, J. Neylan +3 more
2017Journal of the American Society of Nephrology111 citations Open access
Semantic Scholar
(+)-Naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats
Susannah S. Lewis, L. Loram, M. Hutchinson, Chien-Ming Li +5 more
2012Journal of Pain110 citations Open access
Semantic Scholar
Evidence that tricyclic small molecules may possess Toll-like receptor and MD-2 activity
Mark R. Hutchinson, L. Loram, Ying-Ning Zhang, M. Shridhar +10 more
2010Neuroscience101 citations Open access
Semantic Scholar
Release of Plasmid DNA-Encoding IL-10 from PLGA Microparticles Facilitates Long-Term Reversal of Neuropathic Pain Following a Single Intrathecal Administration
R. G. Soderquist, E. Sloane, L. Loram, Jacqueline A. Harrison +10 more
2010Pharmaceutical Research93 citations Open access
Semantic Scholar
Pain intensity and duration can be enhanced by prior challenge: Initial evidence suggestive of a role of microglial priming
Leah E. Hains, L. Loram, Julie L Weiseler, M. Frank +8 more
2010Journal of Pain92 citations Open access
Semantic Scholar
Evidence for a role of heat shock protein-90 (HSP90) in TLR4 mediated pain enhancement in rats
Mark R. Hutchinson, Khara M. Ramos, L. Loram, J. Wieseler +9 more
2009Neuroscience80 citations Open access
Semantic Scholar
Association between serum ferritin and mortality: findings from the USA, Japan and European Dialysis Outcomes and Practice Patterns Study
A. Karaboyas, H. Morgenstern, R. Pisoni, J. Zee +6 more
2018Nephrology, Dialysis and Transplantation74 citations Open access
Semantic Scholar
Differences in the relative involvement of peripherally released interleukin (IL)-6, brain IL-1β and prostanoids in mediating lipopolysaccharide-induced fever and sickness behavior.
L. Harden, I. du Plessis, J. Roth, L. Loram +2 more
2011Psychoneuroendocrinology63 citations
Semantic Scholar
Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy
P. Grace, L. Loram, J. P. Christianson, K. Strand +8 more
2016Brain, behavior, and immunity60 citations Open access
Semantic Scholar
Determinants of ball release speed in schoolboy fast-medium bowlers in cricket.
L. Loram, W. McKinon, S. Wormgoor, G. Rogers +2 more
2005Journal of Sports Medicine and Physical Fitness58 citations
Semantic Scholar
Systemic Administration of an Alpha-7 Nicotinic Acetylcholine Agonist Reverses Neuropathic Pain in Male Sprague Dawley Rats
L. Loram, F. Taylor, K. Strand, S. Maier +10 more
2012Journal of Pain54 citations Open access
Semantic Scholar
Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy
L. Loram, P. Grace, K. Strand, F. Taylor +6 more
2012Brain, behavior, and immunity53 citations Open access
Semantic Scholar
Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation
L. Loram, F. Taylor, K. Strand, M. Frank +4 more
2011Brain, behavior, and immunity53 citations Open access
Semantic Scholar
INTRATHECAL INJECTION OF AN ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONIST ATTENUATES GP120-INDUCED MECHANICAL ALLODYNIA AND SPINAL PRO-INFLAMMATORY CYTOKINE PROFILES IN RATS
L. Loram, Jacqueline A. Harrison, Li Chao, F. Taylor +7 more
2010Brain, behavior, and immunity50 citations Open access
Semantic Scholar
Intrathecal injection of adenosine 2A receptor agonists reversed neuropathic allodynia through protein kinase (PK)A/PKC signaling
L. Loram, F. Taylor, K. Strand, Jacqueline A. Harrison +5 more
2013Brain, behavior, and immunity46 citations Open access
Semantic Scholar
Post-stroke Intranasal (+)-Naloxone Delivery Reduces Microglial Activation and Improves Behavioral Recovery from Ischemic Injury
J. Anttila, Katrina Albert, Emily S. Wires, K. Mätlik +6 more
2018eNeuro42 citations Open access
Semantic Scholar
The time course of inflammatory cytokine secretion in a rat model of postoperative pain does not coincide with the onset of mechanical hyperalgesia.
L. Loram, Andreas C. Themistocleous, L. Fick, P. Kamerman
2007Canadian Journal of Physiology and Pharmacology42 citations
Semantic Scholar
Tramadol is more effective than morphine and amitriptyline against ischaemic pain but not thermal pain in rats.
L. Loram, D. Mitchell, M. Skosana, L. Fick
2007Pharmacological Research40 citations
Semantic Scholar
Sustained reversal of central neuropathic pain induced by a single intrathecal injection of adenosine A2A receptor agonists.
A. Kwilasz, A. Ellis, J. Wieseler, L. Loram +7 more
2018Brain, behavior, and immunity34 citations
Semantic Scholar
Selection, Preparation, and Evaluation of Small- Molecule Inhibitors of Toll-Like Receptor 4
Douglas E Bevan, Alexander J. Martinko, L. Loram, J. A. Stahl +4 more
2010ACS Medicinal Chemistry Letters29 citations Open access
Semantic Scholar
Melanocortin Peptides: Potential Targets in Systemic Lupus Erythematosus
L. Loram, Melissa Elizabeth Culp, Erin Corey Connolly-Strong, S. Sturgill‐Koszycki
2014Inflammation28 citations Open access
Semantic Scholar
PRIOR LAPAROTOMY OR CORTICOSTERONE POTENTIATES LIPOPOLYSACCHARIDE-INDUCED FEVER AND SICKNESS BEHAVIORS
Leah E. Hains, L. Loram, F. Taylor, K. Strand +11 more
2011Journal of Neuroimmunology25 citations Open access
Semantic Scholar
Behavioural, histological and cytokine responses during hyperalgesia induced by carrageenan injection in the rat tail.
L. Loram, A. Fuller, T. Cartmell, B. Mitchell +1 more
2007Physiology and Behavior25 citations
Semantic Scholar
Postoperative Administration of the Analgesic Tramadol, but Not the Selective Cyclooxygenase-2 Inhibitor Parecoxib, Abolishes Postoperative Hyperalgesia in a New Model of Postoperative Pain in Rats
P. Kamerman, A. Koller, L. Loram
2007Pharmacology20 citations
Semantic Scholar
A model of incisional pain: the effects of dermal tail incision on pain behaviours of Sprague Dawley rats.
Juliane Weber, L. Loram, B. Mitchell, Andreas C. Themistocleous
2005Journal of Neuroscience Methods20 citations
Semantic Scholar
Neutralisation of muscle tumour necrosis factor alpha does not attenuate exercise-induced muscle pain but does improve muscle strength in healthy male volunteers
T. Rice, I. Chantler, L. Loram
2007British Journal of Sports Medicine19 citations
Semantic Scholar
Adenosine 2A receptor agonism: a single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats
L. Loram, K. Strand, F. Taylor, E. Sloane +4 more
2015Brain, behavior, and immunity13 citations Open access
Semantic Scholar
Fever and inflammatory cytokine response in rats injected subcutaneously with viral double-stranded RNA analog, polyinosinic:polycytidylic acid (Poly-I:C)
P. Kamerman, M. Skosana, L. Loram, B. Mitchell +1 more
20119 citations
Semantic Scholar
Gender and site of injection do not influence intensity of hypertonic saline-induced muscle pain in healthy volunteers.
L. Loram, E. Horwitz, A. Bentley
2009Manual Therapy9 citations
Semantic Scholar
Swimming enhances bone mass acquisition in growing female rats.
J. McVeigh, S. Kingsley, D. Gray, L. Loram
2010Journal of Sports Science and Medicine7 citations
Semantic Scholar
Differences in the contribution of peripherally-released interleukin (IL)-6, brain IL-1beta and prostanoids in mediating lipopolysaccharide-induced fever and sickness behaviour
L. Harden, I. du Plessi, J. Roth, L. Loram +2 more
20106 citations
Semantic Scholar
Ferric citrate controls serum phosphorus in dialysis patients: retrospective data
Debra J. Hain, M. Marinaro, David W. Koeper, M. A. Rosenthal +6 more
2017Clinical Nephrology5 citations Open access
Semantic Scholar
Evidence for a role of heat shock protein-90 (HSP90) in TLR4 mediated pain enhancement in rats
M. Hutchinson, Khara M. Ramos, L. Loram, J. Wieseler +10 more
20095 citations
Semantic Scholar
( 1 )-Naloxone , an Opioid-Inactive Toll-Like Receptor 4 Signaling Inhibitor , ReversesMultipleModels of Chronic Neuropathic Pain in Rats
Susannah S. Lewis, L. Loram, M. Hutchinson, Chien-Ming Li +5 more
20122 citations
Semantic Scholar
Melanocortin Peptides: Potential Targets in Systemic Lupus Erythematosus
L. Loram, Melissa Elizabeth Culp, Erin Corey Connolly-Strong, S. Sturgill‐Koszycki
2014Inflammation1 citations Open access
Semantic Scholar
The Cardiopulmonary effect of passive movement
L. Loram, S. de Charmoy
20021 citations Open access
Semantic Scholar
Initial results of a CRUK phase I/II, first in human trial of the CAR t-cell engager protein aleta-001 in patients who have received anti-CD19 CAR t-cell therapy for the treatment of b-cell malignancies
S. Chaganti, William Townsend, B. Maybury, S. Paneesha +21 more
2025Blood0 citations
Semantic Scholar
A Model of Viral-induced Hyperalgesia in rats
M. Skosana, L. Loram, P. Kamerman
20160 citations
Semantic Scholar
55. The role of the liver in E. coli-induced memory impairments in aged rats
R. Barrientos, T. H. Arnold, L. Loram, Matthew G. Frank +3 more
20130 citations
Semantic Scholar
210. Rethinking CNS innate immune responses: Sex, pain and drugs of abuse
L. R. Watkins, A. Northcutt, L. Loram, Susannah S. Lewis +3 more
20110 citations
Semantic Scholar
MRI Detection of Spinal Lesions in a Rat MS Model
J. Bluth, L. Loram, Mark S. Brown, K. Hasebroock +3 more
20110 citations
Semantic Scholar
Evidence that tricyclic small molecules may possess Toll-like receptor and MD-2 activity
M. Hutchinson, L. Loram, Ying-Ning Zhang, M. Shridhar +12 more
20100 citations
Semantic Scholar
Adenosine 2A receptor agonist produces long-duration reversal of neuropathic pain via sustained release of spinal interleukin-10
L. Loram, P. Sholar, F. Taylor, Jacqueline A. Harrison +5 more
20090 citations Open access
Semantic Scholar

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