Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

S. Peltz · SciRah

Researcher profile · Semantic Scholar

S. Peltz

Share profile

S. Peltz — researcher profile on SciRah

h-index: 48
Works: 143
Citations: 9,573

Most-cited papers

The cap-to-tail guide to mRNA turnover
C. Wilusz, Michael Wormington, S. Peltz
2001Nature reviews. Molecular cell biology810 citations
Semantic Scholar
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
N. Naryshkin, M. Weetall, A. Dakka, J. Narasimhan +44 more
2014Science455 citations
Semantic Scholar
Ataluren treatment of patients with nonsense mutation dystrophinopathy
K. Bushby, R. Finkel, B. Wong, R. Barohn +30 more
2014Muscle and Nerve416 citations Open access
Semantic Scholar
THE 6-MINUTE WALK TEST AND OTHER CLINICAL ENDPOINTS IN DUCHENNE MUSCULAR DYSTROPHY: RELIABILITY, CONCURRENT VALIDITY, AND MINIMAL CLINICALLY IMPORTANT DIFFERENCES FROM A MULTICENTER STUDY
Craig M. Mcdonald, E. Henricson, R. Abresch, J. Florence +8 more
2013Muscle and Nerve327 citations Open access
Semantic Scholar
THE 6-MINUTE WALK TEST AND OTHER ENDPOINTS IN DUCHENNE MUSCULAR DYSTROPHY: LONGITUDINAL NATURAL HISTORY OBSERVATIONS OVER 48 WEEKS FROM A MULTICENTER STUDY
Craig M. Mcdonald, E. Henricson, R. Abresch, J. Florence +8 more
2013Muscle and Nerve296 citations Open access
Semantic Scholar
PTC124 is an orally bioavailable compound that promotes suppression of the human CFTR-G542X nonsense allele in a CF mouse model
M. Du, Xiaoli Liu, E. Welch, S. Hirawat +2 more
2008Proceedings of the National Academy of Sciences of the United States of America270 citations Open access
Semantic Scholar
Human Immunodeficiency Virus Type 1 Latency Model for High-Throughput Screening
Sofiya N. Micheva-Viteva, Annmarie L. Pacchia, Yacov Ron, S. Peltz +1 more
2005Antimicrobial Agents and Chemotherapy263 citations Open access
Semantic Scholar
Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation.
S. Paushkin, Meenal Patel, B. Furia, S. Peltz +1 more
2004Cell235 citations Open access
Semantic Scholar
Ataluren as an agent for therapeutic nonsense suppression
S. Peltz, M. Morsy, E. Welch, A. Jacobson
2012Annual Review of Medicine201 citations Open access
Semantic Scholar
The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay.
C. González, M. Ruiz-Echevarría, S. Vasudevan, Michael F. Henry +1 more
2000Molecules and Cells166 citations Open access
Semantic Scholar
New Ways of Initiating Translation in Eukaryotes?
Robert J. Schneider, V. Agol, R. Andino, F. Bayard +84 more
2001Molecular and Cellular Biology132 citations Open access
Semantic Scholar
Non-stop decay--a new mRNA surveillance pathway.
S. Vasudevan, S. Peltz, C. Wilusz
2002Bioessays118 citations
Semantic Scholar
The Human Immunodeficiency Virus Type 1 Ribosomal Frameshifting Site Is an Invariant Sequence Determinant and an Important Target for Antiviral Therapy
P. Biswas, Xi Jiang, Annmarie L. Pacchia, J. Dougherty +1 more
2004Journal of Virology105 citations Open access
Semantic Scholar
Poly(A)-binding proteins regulate both mRNA deadenylation and decapping in yeast cytoplasmic extracts.
C. Wilusz, M. Gao, Charles L. Jones, J. Wilusz +1 more
2001RNA: A publication of the RNA Society101 citations
Semantic Scholar
Global Analysis of Pub1p Targets Reveals a Coordinate Control of Gene Expression through Modulation of Binding and Stability
R. Duttagupta, Bin Tian, C. Wilusz, D. T. Khounh +4 more
2005Molecular and Cellular Biology90 citations Open access
Semantic Scholar
A newly discovered function for RNase L in regulating translation termination
F. Le Roy, T. Salehzada, C. Bisbal, J. Dougherty +1 more
2005Nature Structural &Molecular Biology72 citations
Semantic Scholar
Nuclear mRNA surveillance.
S. Vasudevan, S. Peltz
2003Current Opinion in Cell Biology72 citations
Semantic Scholar
Derepression of the Her-2 uORF is mediated by a novel post-transcriptional control mechanism in cancer cells.
A. Mehta, C. Trotta, S. Peltz
2006Genes & Development71 citations Open access
Semantic Scholar
Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties
Liang-Xian Cao, M. Weetall, C. Trotta, Katherine Cintron +25 more
2018Molecular Cancer Therapeutics69 citations Open access
Semantic Scholar
Cleavage of pre-tRNAs by the splicing endonuclease requires a composite active site
C. Trotta, S. Paushkin, Meenal Patel, Hong Li +1 more
2006Nature68 citations
Semantic Scholar
Deflazacort vs prednisone treatment for Duchenne muscular dystrophy: A meta‐analysis of disease progression rates in recent multicenter clinical trials
C. McDonald, G. Sajeev, Z. Yao, E. McDonnell +8 more
2019Muscle and Nerve67 citations Open access
Semantic Scholar
Small molecule splicing modifiers with systemic HTT-lowering activity
Anuradha Bhattacharyya, C. Trotta, J. Narasimhan, Kari Wiedinger +20 more
2021Nature Communications66 citations Open access
Semantic Scholar
Role for Upf2p Phosphorylation in Saccharomyces cerevisiae Nonsense-Mediated mRNA Decay
Wei-Rong Wang, I. Cajigas, S. Peltz, M. Wilkinson +1 more
2006Molecular and Cellular Biology59 citations
Semantic Scholar
Deflazacort versus prednisone/prednisolone for maintaining motor function and delaying loss of ambulation: A post HOC analysis from the ACT DMD trial
P. Shieh, J. Mcintosh, Fengbin Jin, Marcio Souza +6 more
2018Muscle and Nerve57 citations Open access
Semantic Scholar
Identification of a Cellular Factor That Modulates HIV-1 Programmed Ribosomal Frameshifting*
Y. Kobayashi, Jianling Zhuang, S. Peltz, J. Dougherty
2010Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Meta-analyses of ataluren randomized controlled trials in nonsense mutation Duchenne muscular dystrophy.
C. Campbell, R. Barohn, E. Bertini, B. Chabrol +31 more
2020Journal of Comparative Effectiveness Research55 citations Open access
Semantic Scholar
The nucleoside analog clitocine is a potent and efficacious readthrough agent
W. Friesen, C. Trotta, Y. Tomizawa, Jin Zhuo +15 more
2017RNA: A publication of the RNA Society49 citations Open access
Semantic Scholar
High-throughput Screening Uncovers a Compound That Activates Latent HIV-1 and Acts Cooperatively with a Histone Deacetylase (HDAC) Inhibitor*
Sofiya N. Micheva-Viteva, Y. Kobayashi, L. Edelstein, Annmarie L. Pacchia +10 more
2011Journal of Biological Chemistry44 citations Open access
Semantic Scholar
The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines
J. Luban, Rachel A. Sattler, Elke Mühlberger, Jason D Graci +20 more
2020bioRxiv43 citations Open access
Semantic Scholar
Nonsense suppression activity of PTC124 (ataluren)
S. Peltz, E. Welch, A. Jacobson, C. Trotta +3 more
2009Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
A Yeast Homologue of Hsp70, Ssa1p, Regulates Turnover of the MFA2 Transcript through Its AU-Rich 3′ Untranslated Region
R. Duttagupta, S. Vasudevan, C. Wilusz, S. Peltz
2003Molecular and Cellular Biology41 citations Open access
Semantic Scholar
The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential
W. Friesen, Briana Johnson, Jairo L. Sierra, Jin Zhuo +17 more
2018PLoS ONE40 citations Open access
Semantic Scholar
p38 Mitogen-Activated Protein Kinase/Hog1p Regulates Translation of the AU-Rich-Element-Bearing MFA2 Transcript
S. Vasudevan, Nicole Garneau, Danny Tu Khounh, S. Peltz
2005Molecular and Cellular Biology32 citations Open access
Semantic Scholar
29 Destabilization of Nonsense-containing Transcripts in Saccharomyces cerevisiae
A. Jacobson, S. Peltz
200032 citations
Semantic Scholar
The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines
J. Luban, Rachel A. Sattler, Elke Mühlberger, Jason D Graci +19 more
2020Virus Research29 citations Open access
Semantic Scholar
Identification of PTC725, an Orally Bioavailable Small Molecule That Selectively Targets the Hepatitis C Virus NS4B Protein
Zheng-Xiang Gu, Jason D Graci, F. Lahser, Jamie J. Breslin +15 more
2013Antimicrobial Agents and Chemotherapy22 citations Open access
Semantic Scholar
Ambulatory quantitative waking and sleeping cough assessment in patients with cystic fibrosis.
E. Kerem, M. Wilschanski, Nilsen L. Miller, T. Pugatsch +11 more
2011Journal of Cystic Fibrosis21 citations Open access
Semantic Scholar
Nonsense-mediated mRNA decay in Saccharomyces cerevisiae: a quality control mechanism that degrades transcripts harboring premature termination codons.
C. González, W. Wang, S. Peltz
2001Cold Spring Harbor Symposia on Quantitative Biology20 citations
Semantic Scholar
Characterization of a General Stabilizer Element That Blocks Deadenylation-dependent mRNA Decay*
M. Ruiz-Echevarría, R. Munshi, Julie Tomback, T. Kinzy +1 more
2001Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Discovery of Novel Small Molecule Inhibitors of VEGF Expression in Tumor Cells Using a Cell-Based High Throughput Screening Platform
Liang-Xian Cao, M. Weetall, J. Bombard, H. Qi +14 more
2016PLoS ONE19 citations Open access
Semantic Scholar
Phase 1 Study of Safety, Tolerability, and Pharmacokinetics of PTC299, an Inhibitor of Stress‐Regulated Protein Translation
M. Weetall, T. Davis, G. Elfring, V. Northcutt +10 more
2016Clinical pharmacology in drug development18 citations Open access
Semantic Scholar
P3.51 Results of a Phase 2b, dose-ranging study of ataluren (PTC124®) in nonsense mutation Duchenne/Becker muscular dystrophy (nmDBMD)
R. Finkel, B. Wong, K. Bushby, A. Reha +7 more
201018 citations
Semantic Scholar
Targeting post-transcriptional control for drug discovery
S. Peltz, E. Welch, C. Trotta, T. Davis +1 more
2009RNA Biology17 citations Open access
Semantic Scholar
30 Therapeutic Opportunities in Translation
J. Pelletier, S. Peltz
200717 citations
Semantic Scholar
Toward the Development of a Virus-Cell-Based Assay for the Discovery of Novel Compounds against Human Immunodeficiency Virus Type 1
M. Adelson, Annmarie L. Pacchia, M. Kaul, R. Rando +3 more
2003Antimicrobial Agents and Chemotherapy16 citations Open access
Semantic Scholar
Meta-analyses of deflazacort versus prednisone/prednisolone in patients with nonsense mutation Duchenne muscular dystrophy.
P. Shieh, G. Elfring, P. Trifillis, Claudio L Santos +6 more
2021Journal of Comparative Effectiveness Research13 citations Open access
Semantic Scholar
Mining the GEMS--a novel platform technology targeting post-transcriptional control mechanisms.
Anuradha Bhattacharyya, C. Trotta, S. Peltz
2007Drug Discovery Today13 citations
Semantic Scholar
The relationship between deficit in digit span and genotype in nonsense mutation Duchenne muscular dystrophy
M. Thangarajh, G. Elfring, P. Trifillis, J. Mcintosh +1 more
2018Neurology12 citations Open access
Semantic Scholar
WS7.5 Interim results of the phase 3 open-label study of ataluren in nonsense mutation cystic fibrosis (nmCF)
E. Kerem, M. Wilschanski, I. Sermet-Gaudelus, K. De Boeck +9 more
20137 citations Open access
Semantic Scholar
T.P.7 Small molecule compounds correct alternative splicing of the SMN2 gene and restore SMN protein expression and function
N. Naryshkin, J. Narasimhan, A. Dakka, V. Gabbeta +38 more
20116 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

G. Elfring×13
Invite
G. Elfring — researcher profile on SciRah
J. Colacino×12
Invite
J. Colacino — researcher profile on SciRah
C. Trotta×12
Invite
C. Trotta — researcher profile on SciRah
M. Weetall×11
Invite
M. Weetall — researcher profile on SciRah

×11

Invite

E. Welch — researcher profile on SciRah

Invite

Y. Moon — researcher profile on SciRah

P. Trifillis×7

Invite

P. Trifillis — researcher profile on SciRah

J. Dougherty×7

Invite

J. Dougherty — researcher profile on SciRah

Invite

A. Jacobson — researcher profile on SciRah

N. Naryshkin×6

Invite

N. Naryshkin — researcher profile on SciRah

Invite

J. Babiak — researcher profile on SciRah

Invite

N. Almstead — researcher profile on SciRah