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J. Jacków · SciRah

Researcher profile · Semantic Scholar

J. Jacków

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J. Jacków — researcher profile on SciRah

h-index: 16
Works: 57
Citations: 1,543

Most-cited papers

A multi-organ chip with matured tissue niches linked by vascular flow
Kacey Ronaldson-Bouchard, Diogo Teles, K. Yeager, D. Tavakol +22 more
2022Nature Biomedical Engineering440 citations Open access
Semantic Scholar
Tissue engineering of human hair follicles using a biomimetic developmental approach
H. Abaci, A. Coffman, Y. Doucet, James C. Chen +6 more
2018Nature Communications259 citations Open access
Semantic Scholar
CRISPR/Cas9-based targeted genome editing for correction of recessive dystrophic epidermolysis bullosa using iPS cells
J. Jacków, Zong-You Guo, C. Hansen, H. Abaci +8 more
2019Proceedings of the National Academy of Sciences of the United States of America108 citations Open access
Semantic Scholar
Next generation human skin constructs as advanced tools for drug development
HE Abaci, Zong-You Guo, Y. Doucet, J. Jacków +1 more
2017Experimental biology and medicine89 citations Open access
Semantic Scholar
Castration-mediated IL-8 Promotes Myeloid Infiltration and Prostate Cancer Progression
Z. Lopez-Bujanda, Michael C. Haffner, M. Chaimowitz, Nivedita Chowdhury +12 more
2019bioRxiv86 citations Open access
Semantic Scholar
Ectodomain Shedding Generates Neoepitopes on Collagen XVII, the Major Autoantigen for Bullous Pemphigoid
W. Nishie, S. Lamer, A. Schlosser, E. Licărete +5 more
2010Journal of Immunology72 citations Open access
Semantic Scholar
Transmembrane Collagen XVII Modulates Integrin Dependent Keratinocyte Migration via PI3K/Rac1 Signaling
S. Löffek, T. Hurskainen, J. Jacków, F. Sigloch +4 more
2014PLoS ONE68 citations Open access
Semantic Scholar
Recapitulating T cell infiltration in 3D psoriatic skin models for patient-specific drug testing
Jung U. Shin, H. Abaci, Lauren A. Herron, Zong-You Guo +6 more
2020Scientific Reports55 citations Open access
Semantic Scholar
Gene-Corrected Fibroblast Therapy for Recessive Dystrophic Epidermolysis Bullosa using a Self-Inactivating COL7A1 Retroviral Vector.
J. Jacków, M. Titeux, S. Portier, S. Charbonnier +3 more
2016Journal of Investigative Dermatology52 citations Open access
Semantic Scholar
Collagen XVII Shedding Suppresses Re-Epithelialization by Directing Keratinocyte Migration and Dampening mTOR Signaling.
J. Jacków, S. Löffek, A. Nyström, L. Bruckner-Tuderman +1 more
2016Journal of Investigative Dermatology48 citations Open access
Semantic Scholar
Generation of a Functional Non-Shedding Collagen XVII Mouse Model: Relevance of Collagen XVII Shedding in Wound Healing.
J. Jacków, A. Schlosser, R. Sormunen, A. Nyström +4 more
2016Journal of Investigative Dermatology43 citations Open access
Semantic Scholar
Targeting Cancer with CRISPR/Cas9-Based Therapy
K. Balon, A. Sheriff, J. Jacków, Ł. Łaczmański
2022International Journal of Molecular Sciences42 citations Open access
Semantic Scholar
ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation
A. Sheriff, I. Guri, P. Żebrowska, V. Llopis-Hernandez +15 more
2022Scientific Reports40 citations Open access
Semantic Scholar
Deletion of the major bullous pemphigoid epitope region of collagen XVII induces blistering, autoimmunization, and itching in mice.
T. Hurskainen, N. Kokkonen, R. Sormunen, J. Jacków +5 more
2015Journal of Investigative Dermatology38 citations Open access
Semantic Scholar
Coiled Coils Ensure the Physiological Ectodomain Shedding of Collagen XVII*
W. Nishie, J. Jacków, S. Hofmann, C. Franzke +1 more
2012Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Engineering human skin model innervated with itch sensory neuron‐like cells differentiated from induced pluripotent stem cells
Zong-You Guo, C. Tong, J. Jacków, Y. Doucet +9 more
2021Bioengineering & Translational Medicine20 citations Open access
Semantic Scholar
Challenges of Gene Editing Therapies for Genodermatoses
I. Brooks, A. Sheriff, Declan Moran, Jing-Bo Wang +1 more
2023International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa
Gernot Neumayer, J. Torkelson, Sheng-Di Li, K. McCarthy +23 more
2023bioRxiv9 citations Open access
Semantic Scholar
Targeting the JAK/STAT3 pathway with Ruxolitinib in a mouse model of recessive dystrophic epidermolysis bullosa-squamous cell carcinoma.
J. Jacków, Avina Rami, R. Hayashi, C. Hansen +8 more
2020Journal of Investigative Dermatology9 citations Open access
Semantic Scholar
Ancestral Patterns of Recessive Dystrophic Epidermolysis Bullosa Mutations in Hispanic Populations Suggest Sephardic Ancestry
E. Warshauer, Adam T. Brown, I. Fuentes, J. Shortt +24 more
2021American Journal of Medical Genetics. Part A7 citations Open access
Semantic Scholar
Reprogramming and Differentiation of Cutaneous Squamous Cell Carcinoma Cells in Recessive Dystrophic Epidermolysis Bullosa
Avina Rami, Ł. Łaczmański, Jagoda Jacków-Nowicka, J. Jacków
2020International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Lineage tracing mediated by cre-recombinase activity.
S. Vorhagen, J. Jacków, Simona Georgina Mohor, G. Tanghe +3 more
2015Journal of Investigative Dermatology5 citations Open access
Semantic Scholar
P07 Optimizing DNA specificity and applicability of base and prime editors on COL7A1 variants causing recessive dystrophic epidermolysis bullosa
I. Brooks, M. Rudnytska, Ruta Gebrezgabher, L. Laczmanski +4 more
2023British Journal of Dermatology2 citations
Semantic Scholar
1415 Induction of human hair growth using vascularized 3D hair follicle constructs
H. Abaci, A. Coffman, Y. Doucet, J.-C. Ch'en +4 more
20182 citations Open access
Semantic Scholar
P21 Tyrosine and serine STAT3 phosphorylation drives cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa as demonstrated using a 3D in vitro model
V. Llopis-Hernandez, K. Balon, Dawei Chen, J. Mellerio +2 more
2023British Journal of Dermatology1 citations
Semantic Scholar
Gene Editing Therapies for Genodermatoses
A. Sheriff, I. Brooks, J. Jacków
2021New Technologies in Dermatological Science and Practice1 citations
Semantic Scholar
1036 Scalable production of CRISPR-corrected autologous iPSC derived skin grafts to treat epidermolysis bullosa
J. Torkelson, C. Hansen, J. Jacków, Z. Guo +12 more
2019Journal of Investigative Dermatology1 citations Open access
Semantic Scholar
190 Biallelic correction of recessive dystrophic epidermolysis bullosa mutations in iPSCs using CRISPR/Cas9- based genome editing
J. Jacków, Z. Guo, E. Abaci, Y. Doucet +3 more
20171 citations Open access
Semantic Scholar
445 Does tyrosine and serine phosphorylation of STAT3 drive cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa?
V. Llopis-Hernandez, K. Balon, J. Mellerio, J. McGrath +1 more
2022Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
296 Nanoneedles for gene editing in Epidermolysis Bullosa
Salman Ahmad Mustfa, M. Dimitrievska, C. Wang, J. McGrath +2 more
2022Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
474 Ratio-dependent adenine base editing engenders highly efficient correction of RDEB mutations with minimal bystander mutations
A. Sheriff, I. Guri, P. Żebrowska, V. L. Hernandez +6 more
2022Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
299 High efficiency and safe base editor correction of recurrent COL7A1 mutations underlying dominant dystrophic epidermolysis bullosa
M. Dimitrievska, J. McGrath, J. Jacków
2022Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
268 ABE8e adenine base editor corrects COL7A1 nonsense mutation efficiently and safely
A. Sheriff, I. Guri, P. Żebrowska, V. Llopis-Hernandez +6 more
2022Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
283 Optimising specificity and applicability of base editing for COL7A1 mutations in recessive dystrophic epidermolysis bullosa
I. Brooks, P. Żebrowska, L. Laczmanski, J. McGrath +1 more
2022Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
165 Allelic specific COL7A1 correction in dominant dystrophic epidermolysis bullosa fibroblasts
S. Tekkela, A. Sheriff, G. Naso, A. Petrova +4 more
2021Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
157 Comparing adenine base editing and CRISPR-Cas9 gene editing strategies to correct recurrent mutations in RDEB primary fibroblasts
A. Sheriff, S. Tekkela, I. Brooks, G. Naso +6 more
2021Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
968 Enhancing the efficiency of engineered hair follicles with master regulators and extrinsic factors
H. Abaci, A. Coffman, Y. Doucet, J.-C. Ch'en +4 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
924 Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in iPS cells for recessive dystrophic epidermolysis bullosa
J. Jacków, Z. Guo, H. Abaci, Y. Doucet +6 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
358 Bioinformatic analysis of keratinocyte differentiation from induce pluripotent stem cells
Z. Guo, J. Jacków, D. DeLorenzo, R. Hayashi +2 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
475 Targeting the JAK/STAT3 pathway with ruxolitinib for RDEB-cSCC therapy
J. Jacków, R. Hayashi, David M. Owens, R. Pérez-Lorenzo +4 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
660 Recapitulating T cell infiltration in psoriasis for patient-specific drug testing models
J. Shin, H. Abaci, L. Herron, Z. Guo +4 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
413 One-step iPSC-reprogramming and genome-editing on primary fibroblasts using CRISPR/Cas9 ribonuleoprotein approach for recessive dystrophic epidermolysis bullosa
R. Hayashi, J. Jacków, C. Hansen, D. DeLorenzo +3 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
147 Ruxolitinib reverses accelerated tumor growth of RDEB-cSCCs in a xenograft mouse model
J. Jacków, C. Hansen, David M. Owens, R. Pérez-Lorenzo +4 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
1039 Novel mouse model of recessive dystrophic epidermolysis bullosa-squamous cell carcinoma
J. Jacków, C. Hansen, R. Hayashi, D. Owens +4 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
1041 Development of human skin spheroid system for psoriatic disease modeling and drug development
Z. Guo, J. Jacków, W. Zeng, C. Hansen +5 more
2019Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
Deposited in DRO : 03 January 2019 Version of attached
H. Abaci, A. Coffman, Y. Doucet, James C. Chen +6 more
20190 citations
Semantic Scholar
1446 Atopic cytokines IL4/13 perturb iPSC-derived itch-specific sensory neurons
Z. Guo, C. Tong, Y. Doucet, H. Abaci +5 more
20180 citations Open access
Semantic Scholar
1448 Development of immune-competent human skin constructs to model inflammatory skin diseases
J. Shin, H. Abaci, Z. Guo, F. Magrelli +4 more
20180 citations Open access
Semantic Scholar
798 Biallelic COL7A1 editing in iPSCs via CRISPR/Cas9 for recessive dystrophic epidermolysis bullosa mutations
J. Jacków, Z. Guo, H. Abaci, Y. Doucet +4 more
20180 citations Open access
Semantic Scholar
198 The JAK1/2 inhibitor ruxolitinib induces cell cycle arrest and apoptosis through inhibiting STAT3 phosphorylation in squamous cell carcinoma
J. Jacków, R. Pérez-Lorenzo, C. Hansen, David M. Owens +1 more
20180 citations Open access
Semantic Scholar

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