I. Brooks

Most-cited papers

1. ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

   A. Sheriff, I. Guri, P. Żebrowska, V. Llopis-Hernandez +15 more

   2022Scientific Reports40 citations Open access

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2. Challenges of Gene Editing Therapies for Genodermatoses

   I. Brooks, A. Sheriff, Declan Moran, Jing-Bo Wang +1 more

   2023International Journal of Molecular Sciences16 citations Open access

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3. Highly efficient bi-allelic correction of homozygous COL7A1 mutation using ABE8e adenine base editor.

   I. Brooks, Yara Alrokh, A. Kazemizadeh, K. Balon +5 more

   2023British Journal of Dermatology2 citations Open access

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4. P07 Optimizing DNA specificity and applicability of base and prime editors on COL7A1 variants causing recessive dystrophic epidermolysis bullosa

   I. Brooks, M. Rudnytska, Ruta Gebrezgabher, L. Laczmanski +4 more

   2023British Journal of Dermatology2 citations

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5. Gene Editing Therapies for Genodermatoses

   A. Sheriff, I. Brooks, J. Jacków

   2021New Technologies in Dermatological Science and Practice1 citations

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6. O14 Next-generation sequencing precision: on- and off-target analysis of gene editing in recessive dystrophic epidermolysis bullosa

   A. Kazemizadeh, I. Brooks, Carina Graham, Yara Alrokh +5 more

   2026British Journal of Dermatology0 citations

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7. O17 Highly efficient base editing of homozygous and heterozygous COL7A1 variants in fibroblasts from patients with recessive dystrophic epidermolysis bullosa using adenine base editor 8e mRNA system delivered via novel lipid nanoparticle formulations

   I. Guri, I. Brooks, Yara Alrokh, Aidni Kazamizadeh +4 more

   2024British Journal of Dermatology0 citations

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8. P09 Next-generation sequencing: on-and off-target analysis of gene editing in fibroblasts from patients with recessive dystrophic epidermolysis bullosa

   A. Kazemizadeh, I. Brooks, I. Guri, Yara Alrokh +4 more

   2024British Journal of Dermatology0 citations

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9. 884 Reproducible correction of COL7A1 nonsense variants with ABE8e adenine base editor

   J. K. Jackow, A. Sheriff, I. Guri, I. Brooks +5 more

   2023Journal of Investigative Dermatology0 citations Open access

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10. 474 Ratio-dependent adenine base editing engenders highly efficient correction of RDEB mutations with minimal bystander mutations

    A. Sheriff, I. Guri, P. Żebrowska, V. L. Hernandez +6 more

    2022Journal of Investigative Dermatology0 citations Open access

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11. 268 ABE8e adenine base editor corrects COL7A1 nonsense mutation efficiently and safely

    A. Sheriff, I. Guri, P. Żebrowska, V. Llopis-Hernandez +6 more

    2022Journal of Investigative Dermatology0 citations Open access

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12. 283 Optimising specificity and applicability of base editing for COL7A1 mutations in recessive dystrophic epidermolysis bullosa

    I. Brooks, P. Żebrowska, L. Laczmanski, J. McGrath +1 more

    2022Journal of Investigative Dermatology0 citations Open access

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13. 157 Comparing adenine base editing and CRISPR-Cas9 gene editing strategies to correct recurrent mutations in RDEB primary fibroblasts

    A. Sheriff, S. Tekkela, I. Brooks, G. Naso +6 more

    2021Journal of Investigative Dermatology0 citations Open access

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