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S. Dewire · SciRah

Researcher profile · Semantic Scholar

S. Dewire

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S. Dewire — researcher profile on SciRah

h-index: 20
Works: 29
Citations: 5,304

Most-cited papers

β-Arrestins and Cell Signaling
S. Dewire, Seungkirl Ahn, R. Lefkowitz, Sudha K. Shenoy
20071,263 citations Open access
Semantic Scholar
Beta-arrestins and cell signaling.
S. Dewire, Seungkirl Ahn, R. Lefkowitz, Sudha K. Shenoy
2007Annual Review of Physiology707 citations
Semantic Scholar
A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine
S. Dewire, D. Yamashita, D. Rominger, Guodong Liu +9 more
2013Journal of Pharmacology and Experimental Therapeutics629 citations
Semantic Scholar
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
James W. Wisler, S. Dewire, E. Whalen, Jonathan D. Violin +4 more
2007Proceedings of the National Academy of Sciences of the United States of America556 citations Open access
Semantic Scholar
Quantifying Ligand Bias at Seven-Transmembrane Receptors
S. Rajagopal, Seungkirl Ahn, D. Rominger, W. Gowen-MacDonald +4 more
2011Molecular Pharmacology390 citations Open access
Semantic Scholar
Selectively Engaging β-Arrestins at the Angiotensin II Type 1 Receptor Reduces Blood Pressure and Increases Cardiac Performance
Jonathan D. Violin, S. Dewire, D. Yamashita, D. Rominger +5 more
2010Journal of Pharmacology and Experimental Therapeutics373 citations
Semantic Scholar
A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling.
James W. Wisler, S. Dewire, E. Whalen, Jonathan D. Violin +4 more
2007Proceedings of the National Academy of Sciences of the United States of America255 citations
Semantic Scholar
Structure-activity relationships and discovery of a G protein biased μ opioid receptor ligand, [(3-methoxythiophen-2-yl)methyl]({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro-[4.5]decan-9-yl]ethyl})amine (TRV130), for the treatment of acute severe pain.
Xiao-Tao Chen, P. Pitis, Guodong Liu, Catherine C. K. Yuan +8 more
2013Journal of Medicinal Chemistry198 citations Open access
Semantic Scholar
The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factors.
Ling Wang, N. Wakisaka, C. Tomlinson, S. Dewire +3 more
2004Cancer Research180 citations Open access
Semantic Scholar
Biased ligands for better cardiovascular drugs: dissecting G-protein-coupled receptor pharmacology.
S. Dewire, Jonathan D. Violin
2011Circulation Research139 citations Open access
Semantic Scholar
β-Arrestin-mediated Signaling Regulates Protein Synthesis*
S. Dewire, Jihee Kim, E. Whalen, Seungkirl Ahn +2 more
2008Journal of Biological Chemistry104 citations Open access
Semantic Scholar
&bgr;-Arrestins Regulate Atherosclerosis and Neointimal Hyperplasia by Controlling Smooth Muscle Cell Proliferation and Migration
Jihee Kim, Li-Sheng Zhang, K. Peppel, Jiao‐Hui Wu +6 more
2008Circulation Research92 citations Open access
Semantic Scholar
G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics*
Jonathan D. Violin, S. Dewire, W. Barnes, R. Lefkowitz
2006Journal of Biological Chemistry88 citations Open access
Semantic Scholar
Transcriptional Regulation of the K1 Gene Product of Kaposi's Sarcoma-Associated Herpesvirus
Brian S. Bowser, S. Dewire, B. Damania
2002Journal of Virology65 citations Open access
Semantic Scholar
Comparison of the Rta/Orf50 Transactivator Proteins of Gamma-2-Herpesviruses
B. Damania, Joseph H. Jeong, Brian S. Bowser, S. Dewire +2 more
2004Journal of Virology62 citations Open access
Semantic Scholar
Whole-Genome Transcription Profiling of Rhesus Monkey Rhadinovirus
D. Dittmer, Carlos M. González, W. Vahrson, S. Dewire +2 more
2005Journal of Virology48 citations Open access
Semantic Scholar
Kinetics of Expression of Rhesus Monkey Rhadinovirus (RRV) and Identification and Characterization of a Polycistronic Transcript Encoding the RRV Orf50/Rta, RRV R8, and R8.1 Genes
S. Dewire, Michael A. McVoy, B. Damania
2002Journal of Virology47 citations Open access
Semantic Scholar
The Latency-Associated Nuclear Antigen of Rhesus Monkey Rhadinovirus Inhibits Viral Replication through Repression of Orf50/Rta Transcriptional Activation
S. Dewire, B. Damania
2005Journal of Virology40 citations Open access
Semantic Scholar
Rhesus monkey rhadinovirus (RRV): construction of a RRV-GFP recombinant virus and development of assays to assess viral replication.
S. Dewire, E. Money, Stuart P. Krall, B. Damania
2003Virology38 citations Open access
Semantic Scholar
Unexpected Potency Differences between B-Cell–Activating Factor (BAFF) Antagonist Antibodies against Various Forms of BAFF: Trimer, 60-Mer, and Membrane-Bound
A. Nicoletti, C. Kenny, Ashraf M Khalil, Qi Pan +6 more
2016Journal of Pharmacology and Experimental Therapeutics21 citations
Semantic Scholar
. 5 ] decan-9-yl ] ethyl } ) amine ( TRV 130 ) , for the Treatment of Acute Severe Pain
Xiao-Tao Chen, P. Pitis, Guodong Liu, Catherine C. K. Yuan +8 more
20133 citations
Semantic Scholar
Biased Ligands for Better Cardiovascular Drugs Dissecting G-Protein-Coupled Receptor Pharmacology
S. Dewire, Jonathan D. Violin
20113 citations
Semantic Scholar
G-Protein-Dependent and -Independent Signaling Pathways and their Impact on Cardiac Function Compartmentalization of b-Adrenergic Signals in Cardiomyocytes G-Protein-Coupled Receptor Kinases (GRK) as Therapeutic Targets in Cardiovascular Disease Regulators of G-Protein Signaling in the Heart and The
S. Dewire, Jonathan D. Violin
20112 citations
Semantic Scholar
TRV120027, a β-Arrestin Biased Ligand at the Angiotensin II Type 1 Receptor, Produces Unique Pharmacology and Is a Novel Potential Therapy for Heart Failure
Jonathan D. Violin, D. Soergel, S. Dewire, D. Yamashita +4 more
20102 citations
Semantic Scholar
Dissecting G-Protein-Coupled Receptor Pharmacology
S. Dewire, Jonathan D. Violin
20111 citations
Semantic Scholar
1 GRK AND β-ARRESTIN MEDIATED DESENSITIZATION OF THE ANGIOTENSIN II TYPE 1 A RECEPTOR ELUCIDATED BY DIACYLGLYCEROL DYNAMICS
Jonathan D. Violin, S. Dewire, W. Barnes, R. Lefkowitz
20061 citations
Semantic Scholar
International Headache Congress 2015 late breaking abstracts (orals)
L. Maretty, J. Sibbesen, R. Ramachandran, V. Yakimov +22 more
20150 citations
Semantic Scholar
An orally available mu-opioid receptor biased ligand is analgesic with reduced constipation in rodents
Jonathan D. Violin, S. Dewire, Michael Koblish, D. Chen +4 more
20130 citations Open access
Semantic Scholar
Biased Ligands for Better Cardiovascular Drugs Dissecting G-Protein-Coupled Receptor Pharmacology
S. Dewire, Jonathan D. Violin
20110 citations
Semantic Scholar

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Jonathan D. Violin — researcher profile on SciRah
R. Lefkowitz×9
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Seungkirl Ahn×6
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D. Yamashita — researcher profile on SciRah

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Sudha K. Shenoy×4

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